公开(公告)号：US10294503B2

公开(公告)日：2019-05-21

申请号：US15946286

申请日：2018-04-05

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Thomas Craig Masterman ,  James Lynch

IPC: C12N9/42 ,  C12P5/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/16 ,  C12P7/24 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/56 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P19/12 ,  C12P19/14

Abstract: Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing.

公开(公告)号：US09963730B2

公开(公告)日：2018-05-08

申请号：US15596658

申请日：2017-05-16

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Thomas Craig Masterman ,  James Lynch

IPC: C12P19/14 ,  C12P7/10 ,  C12N9/42 ,  C12P5/02 ,  C12P7/04 ,  C12P7/16 ,  C12P7/24 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/56 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P19/12

CPC classification number: C12P19/14 ,  C12N9/2434 ,  C12N9/2437 ,  C12P5/02 ,  C12P5/023 ,  C12P7/04 ,  C12P7/10 ,  C12P7/16 ,  C12P7/24 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/56 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P19/12 ,  C12P2201/00 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02E50/17 ,  Y02E50/343

Abstract: Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing.

公开(公告)号：US20170137797A1

公开(公告)日：2017-05-18

申请号：US14768126

申请日：2015-08-07

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12N9/2445 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01021

Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.

公开(公告)号：US20190316108A1

公开(公告)日：2019-10-17

申请号：US16456536

申请日：2019-06-28

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/14 ,  C12P19/02

Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.

公开(公告)号：US09683249B2

公开(公告)日：2017-06-20

申请号：US14016461

申请日：2013-09-03

Applicant: Xyleco, Inc.

Inventor： Marshall Medoff ,  Thomas Craig Masterman ,  James Lynch

IPC: C12P19/14 ,  C12P7/10 ,  C12N9/42 ,  C12P5/02 ,  C12P7/04 ,  C12P7/16 ,  C12P7/24 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/56 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P19/12

CPC classification number: C12P19/14 ,  C12N9/2434 ,  C12N9/2437 ,  C12P5/02 ,  C12P5/023 ,  C12P7/04 ,  C12P7/10 ,  C12P7/16 ,  C12P7/24 ,  C12P7/28 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P7/48 ,  C12P7/52 ,  C12P7/56 ,  C12P7/62 ,  C12P19/02 ,  C12P19/04 ,  C12P19/12 ,  C12P2201/00 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02E50/17 ,  Y02E50/343

Abstract: Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a mesh or any combination of these. Containing the material in this manner allows it to be readily added or removed at any point and in any sequence during processing.

公开(公告)号：US20160222366A1

公开(公告)日：2016-08-04

申请号：US14782205

申请日：2015-09-25

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/14 ,  C12P19/02

CPC classification number: C12N9/2445 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01021

Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.

Abstract translation: 本发明涉及包含多肽或多肽的混合物，其具有从包涵体溶解的生物降解活性，并保持生物降解活性，以及​​生产和使用该生物降解活性的方法。 本文描述的本发明提供了用于从宿主细胞分离的用生物降解活性提高重组蛋白的产量的方法。