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    Endoscopic imaging system including removable deflection device
    1.
    发明申请
    Endoscopic imaging system including removable deflection device 审中-公开
    内窥镜成像系统包括可移除的偏转装置

    公开(公告)号：US20050215859A1

    公开(公告)日：2005-09-29

    申请号：US11132464

    申请日：2005-05-18

    申请人： Yem Chin ,  Louis Barbato ,  Michael Banik

    发明人： Yem Chin ,  Louis Barbato ,  Michael Banik

    IPC分类号： A61B1/005 ,  A61B1/012 ,  A61B1/04 ,  A61B1/01 ,  A61B1/06

    CPC分类号： A61B1/0051 ,  A61B1/00071 ,  A61B1/00105 ,  A61B1/0055 ,  A61B1/012 ,  A61B1/06 ,  A61B1/0607 ,  A61B1/0638 ,  A61B1/0676 ,  A61B1/0684

    摘要： A steerable endoscopic sheath has a proximal end, a distal end and a working channel lumen disposed therein. A plurality of solid state light emitting devices such as light emitting diodes are positioned near the distal end of the sheath and are selectively energized to illuminate internal body tissues. An imaging device such as a photo diode or CCD array creates an image from light reflected from the tissue. The distal tip of the endoscopic sheath is selectively moveable with a deflection device that is insertable into the sheath. The deflection device includes a tip deflection mechanism that allows a user to move the tip of the deflection device. With the deflection device inserted in the sheath, movement of the distal tip causes a corresponding movement in the distal tip of the sheath. The distal tip of the sheath has a shape retaining mechanism that allows it to retain the shape imparted by the deflection device once the deflection device is removed from the sheath.

    摘要翻译： 可操纵的内窥镜护套具有设置在其中的近端，远端和工作通道腔。 多个固态发光器件如发光二极管位于护套的远端附近，并且被选择性地通电以照亮内部身体组织。 诸如光电二极管或CCD阵列的成像装置从组织反射的光产生图像。 内窥镜护套的远端可选择性地与可插入护套中的偏转装置一起移动。 偏转装置包括允许使用者移动偏转装置的尖端的尖端偏转机构。 当偏转装置插入护套中时，远侧末端的移动导致护套的远侧末端中的相应运动。 护套的远侧末端具有形状保持机构，一旦偏转装置从护套中移除，其允许其保持由偏转装置赋予的形状。

    Rotating measuring device
    2.
    发明申请
    Rotating measuring device 审中-公开
    旋转测量装置

    公开(公告)号：US20050113701A1

    公开(公告)日：2005-05-26

    申请号：US10723847

    申请日：2003-11-26

    申请人： Yem Chin ,  Louis Barbato

    发明人： Yem Chin ,  Louis Barbato

    IPC分类号： A61B5/00 ,  A61B5/107 ,  G01B9/02 ,  G01D5/353 ,  A61B6/00

    CPC分类号： A61B5/0084 ,  A61B5/1076 ,  G01D5/35303

    摘要： A system for measuring internal body cavities of a patient includes an interferometer having a reference leg and a patient leg that is inserted in the patient. The patient leg directs a beam of coherent light within a body cavity of the patient. Light exiting the patient leg is reflected by a tissue wall and is received by the patient leg where it is combined with light that is reflected through the reference leg. The light in the reference leg and patient leg combines to create fringes indicative of a difference in the optical path length between the two legs. A processor computes the dimensions of the body cavity from the difference in optical path length between the patient leg and the reference leg.

    摘要翻译： 用于测量患者体内腔体的系统包括具有插入患者体内的参考腿和患者腿的干涉仪。 患者腿将一束相干光引导到患者体腔内。 离开患者腿的光被组织壁反射并被患者腿接收，在那里与通过参考腿反射的光结合。 参考腿和患者腿中的光结合以产生指示两条腿之间的光程长度差异的条纹。 处理器根据患者腿和参考腿之间的光程长度的差异来计算体腔的尺寸。

    Vision catheter
    3.
    发明申请
    Vision catheter 审中-公开
    视力导管

    公开(公告)号：US20050027163A1

    公开(公告)日：2005-02-03

    申请号：US10630440

    申请日：2003-07-29

    申请人： Yem Chin ,  Louis Barbato ,  Mark Hamm

    发明人： Yem Chin ,  Louis Barbato ,  Mark Hamm

    IPC分类号： A61B1/005 ,  A61B1/04 ,  A61B1/07 ,  A61B1/00

    CPC分类号： A61B1/0051 ,  A61B1/0008 ,  A61B1/00096 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/00183 ,  A61B1/07

    摘要： A catheter with a small optical fiber or bundle of fibers includes a scanning mechanism constructed with the use of any vibration capable component. Magnetic, piezoelectric or other mechanisms are used to vibrate the end of the fiber and thus create a scanning effect which extends the field of view. This configuration can be used in a catheter with a relatively small diameter. A glass lens or lenses placed in front of the fiber focuses and magnifies the image. A CCD, CMOS, or photodiode camera at the proximal end of the fiber captures the image and transfers it to a computer or processor. A light splitter coupled to a light source provides light through an illumination fiber. The resulting vision catheter is relatively inexpensive and disposable.

    摘要翻译： 具有小光纤或纤维束的导管包括使用任何具有振动能力的部件构成的扫描机构。 使用磁性，压电或其他机构来振动纤维的端部，从而产生延伸视野的扫描效果。 这种构造可以用于具有相对较小直径的导管中。 置于纤维前面的玻璃镜片或镜片聚焦并放大图像。 光纤近端的CCD，CMOS或光电二极管相机捕获图像并将其传输到计算机或处理器。 耦合到光源的光分路器通过照明光纤提供光。 所得到的视觉导管相对便宜并且是一次性的。

    Vision catheter system
    4.
    发明申请
    Vision catheter system 失效
    视力导管系统

    公开(公告)号：US20050197534A1

    公开(公告)日：2005-09-08

    申请号：US10793483

    申请日：2004-03-04

    申请人： Louis Barbato ,  Mark Hamm ,  Yem Chin

    发明人： Louis Barbato ,  Mark Hamm ,  Yem Chin

    IPC分类号： A61B1/04 ,  A61B1/313

    CPC分类号： A61B1/3137

    摘要： A disposable imaging catheter that produces high resolution, color images comparable to those obtained from an endoscope. The device may also be made to function as a guidewire. The device may also include a sheath which slides over the catheter body for stiffening and which may include a working channel for accepting interventional devices, as well as LEDs to illuminate the field of view. The vision catheter system includes a detector assembly, scanning mechanism, and distal objective lens. In one embodiment, a photodetector is mated to a lens/pinhole assembly that allows the detector to read light from a small discrete point. This assembly is then scanned in raster or spiral patterns via electric wire coils that actuate a magnetic scan plate to read the area of interest. By adding a fixed objective lens, such as an aspheric lens that is attached to the distal tip of the catheter body, the field of view or acceptance angle of the system is magnified, yielding a wide angle image similar to that commonly obtained from an endoscope.

    摘要翻译： 一次性成像导管，其产生与从内窥镜获得的那些相当的高分辨率彩色图像。 该装置也可以用作导丝。 该装置还可以包括在导管主体上滑动以用于加强的护套，并且可以包括用于接受介入装置的工作通道以及照亮视场的LED。 视觉导管系统包括检测器组件，扫描机构和远端物镜。 在一个实施例中，光电检测器与透镜/针孔组件配合，允许检测器从小的离散点读取光。 然后通过电磁线圈以光栅或螺旋图案扫描该组件，该电线线圈致动磁扫描板以读取感兴趣的区域。 通过添加诸如安装在导管主体的远端顶端的非球面透镜的固定物镜，系统的视野或接收角度被放大，产生类似于从内窥镜获得的广角图像 。

    Vision catheter
    6.
    发明申请
    Vision catheter 审中-公开
    视力导管

    公开(公告)号：US20050027164A1

    公开(公告)日：2005-02-03

    申请号：US10793482

    申请日：2004-03-04

    申请人： Louis Barbato ,  Mark Hamm ,  Yem Chin

    发明人： Louis Barbato ,  Mark Hamm ,  Yem Chin

    IPC分类号： A61B1/005 ,  A61B1/04 ,  A61B1/07 ,  A61B1/00

    CPC分类号： A61B1/07 ,  A61B1/0008 ,  A61B1/00096 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/00183 ,  A61B1/0051

    摘要： A catheter with a small optical fiber or bundle of fibers includes a scanning mechanism constructed with the use of any vibration capable component. Magnetic, piezoelectric or other mechanisms are used to vibrate the end of the fiber and thus create a scanning effect which extends the field of view. One or more lenses may be utilized, including a lens attached to the distal tip of the image fiber, or a lens attached to the distal tip of the catheter for creating an image plane which can be scanned by the fiber. In one embodiment, multiple light sources may be connected to the fiber for enabling the use of field sequential color techniques for real-time imaging, as well as real-time fluorescent imaging for disease detection. A photodetector assembly connected to the proximal end may contain both filtered and unfiltered detectors for use with both standard imaging and fluorescent imaging. The resulting vision catheter is relatively inexpensive and disposable.

    摘要翻译： 具有小光纤或纤维束的导管包括使用任何具有振动能力的部件构成的扫描机构。 使用磁性，压电或其他机构来振动纤维的端部，从而产生延伸视野的扫描效果。 可以使用一个或多个透镜，包括附接到图像纤维的远端的透镜，或附接到导管的远侧末端的透镜，用于产生可由光纤扫描的图像平面。 在一个实施例中，多个光源可以连接到光纤，以使得能够使用用于实时成像的场顺序彩色技术，以及用于疾病检测的实时荧光成像。 连接到近端的光电检测器组件可以包含用于标准成像和荧光成像两者的过滤和未过滤的检测器。 所得到的视觉导管相对便宜并且是一次性的。

    Energetically-controlled delivery of biologically active material from an implanted medical device
    8.
    发明申请
    Energetically-controlled delivery of biologically active material from an implanted medical device 有权
    从植入式医疗装置对生物活性材料进行能量控制递送

    公开(公告)号：US20070010871A1

    公开(公告)日：2007-01-11

    申请号：US11514618

    申请日：2006-09-01

    申请人： Mark Hamm ,  Louis Barbato ,  Robert Crowley ,  Wendy Naimark ,  Hatal Patel

    发明人： Mark Hamm ,  Louis Barbato ,  Robert Crowley ,  Wendy Naimark ,  Hatal Patel

    IPC分类号： A61F2/06

    CPC分类号： A61K31/335 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L31/18 ,  A61L2420/08

    摘要： A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer comprising a biologically active material and optionally a polymeric material is disposed on the surface of the medical device. A second coating layer comprising magnetic particles and a polymeric material is disposed on the first coating layer. The second coating layer, which is substantially free of a biologically active material, protects the biologically active material prior to delivery. The system includes the medical device and a source of energy, such as an electromagnetic or mechanical vibrational energy. When the patient is exposed to the energy source, the magnetic particles move out of the second coating layer and create channels therein through which the biologically active material can be released.

    摘要翻译： 能够向体腔患者提供生物活性物质的按需递送的医疗装置和系统以及制造这种医疗装置的方法。 包含生物活性材料和任选的聚合材料的第一涂层设置在医疗装置的表面上。 包含磁性颗粒和聚合物材料的第二涂层设置在第一涂层上。 基本上不含生物活性物质的第二涂层在输送之前保护生物活性物质。 该系统包括医疗装置和能量源，例如电磁或机械振动能量。 当患者暴露于能量源时，磁性颗粒从第二涂层移出并在其中产生通道，通过该通道释放生物活性物质。

    Electronically scanned optical coherence tomography with frequency modulated signals
    9.
    发明申请
    Electronically scanned optical coherence tomography with frequency modulated signals 审中-公开

    公开(公告)号：US20060106320A1

    公开(公告)日：2006-05-18

    申请号：US11284684

    申请日：2005-11-21

    申请人： Louis Barbato

    发明人： Louis Barbato

    IPC分类号： A61B6/00

    CPC分类号： A61B5/0066 ,  A61B5/6852 ,  G01B9/02002 ,  G01B9/02028 ,  G01B9/02091

    摘要： An improved Optical Coherence Domain Reflectometry (OCDR) system is provided. One embodiment of this OCDR system outputs a detector signal carrying image depth information on multiple modulation frequencies, where each modulation frequency corresponds to a different image depth. The image depth information from the detector signal may be resolved by tuning to the desired modulation frequency. Another system for imaging body tissue uses multiple frequency modulators such that the light beam does not travel from an optical fiber to free space.

    Transducer/sensor assembly
    10.
    发明申请
    Transducer/sensor assembly 有权
    传感器/传感器组件

    公开(公告)号：US20050085716A1

    公开(公告)日：2005-04-21

    申请号：US10689767

    申请日：2003-10-20

    申请人： Mark Hamm ,  Louis Barbato ,  Isaac Ostrovsky

    发明人： Mark Hamm ,  Louis Barbato ,  Isaac Ostrovsky

    IPC分类号： A61B5/06 ,  A61B8/12 ,  A61B5/05 ,  A61B8/14

    CPC分类号： A61B8/12 ,  A61B5/06 ,  A61B8/445 ,  A61B8/4461

    摘要： An imaging transducer assembly is combined with a sensor of a medical positioning system, forming a transducer/sensor assembly. In one embodiment, the sensor includes a coil proximally coupled with the imaging transducer. A cable having first and second wires are proximally coupled to the coil. A non-conductive potting layer is wrapped around the coil. Traces are formed in the non-conductive potting layer that are used to electrically couple the imaging transducer with the first and second wires of the cable.

    摘要翻译： 成像传感器组件与医疗定位系统的传感器组合，形成换能器/传感器组件。 在一个实施例中，传感器包括与成像换能器近端耦合的线圈。 具有第一和第二导线的电缆近端耦合到线圈。 线圈周围缠绕着不导电的灌封层。 轨迹形成在非导电灌封层中，用于将成像换能器与电缆的第一和第二线电耦合。