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公开(公告)号：US08481690B2
公开(公告)日：2013-07-09
申请号：US12512479
申请日：2009-07-30
CPC分类号： G01N33/53 , C07C279/12 , C07K16/44 , G01N33/54366 , G01N33/6812
摘要： Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.
摘要翻译： 检测生物样品中对称二甲基精氨酸（SDMA）的方法。 SDMA类似物用于产生与不对称的二甲基精氨酸，精氨酸和单甲基精氨酸几乎没有或没有交叉反应性的抗SDMA抗体。 类似物具有受保护或游离的硫醇（-SH）基团或羟基（-OH）基团，其允许它们连接到合适的缀合靶标，其可以是例如含蛋白质的标记分子。 抗SDMA抗体可用于诊断免疫测定以诊断SDMA相关疾病和/或疾病。
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公开(公告)号：US20100035274A1
公开(公告)日：2010-02-11
申请号：US12512479
申请日：2009-07-30
IPC分类号： G01N33/53 , C07C237/06 , C07K16/00 , C12M1/34
CPC分类号： G01N33/53 , C07C279/12 , C07K16/44 , G01N33/54366 , G01N33/6812
摘要： Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.
摘要翻译： 检测生物样品中对称二甲基精氨酸（SDMA）的方法。 SDMA类似物用于产生与不对称的二甲基精氨酸，精氨酸和单甲基精氨酸几乎没有或没有交叉反应性的抗SDMA抗体。 类似物具有受保护或游离的硫醇（-SH）基团或羟基（-OH）基团，其允许它们连接到合适的缀合靶标，其可以是例如含蛋白质的标记分子。 抗SDMA抗体可用于诊断免疫测定以诊断SDMA相关疾病和/或疾病。
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公开(公告)号：US09061343B2
公开(公告)日：2015-06-23
申请号：US13215055
申请日：2011-08-22
申请人： Evan D. Watkins , Michael Atkinson
发明人： Evan D. Watkins , Michael Atkinson
CPC分类号： B21D51/2692 , B21D43/05 , B21D51/2638 , B21K21/12
摘要： A machine may include a plurality of stations, e.g., for performing progressive die-necking of open-ended container bodies. A conveyer may be provided to index the open-ended container bodies in a linear manner through the machine from station to station.
摘要翻译： 机器可以包括多个站，例如用于执行开放式容器主体的渐进式缩颈。 可以提供一种输送机，用于以线性方式通过机器从站到站索引开放式容器体。
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公开(公告)号：US20120042708A1
公开(公告)日：2012-02-23
申请号：US13215055
申请日：2011-08-22
申请人： Evan D. Watkins , Michael Atkinson
发明人： Evan D. Watkins , Michael Atkinson
CPC分类号： B21D51/2692 , B21D43/05 , B21D51/2638 , B21K21/12
摘要： A machine may include a plurality of stations, e.g., for performing progressive die-necking of open-ended container bodies. A conveyer may be provided to index the open-ended container bodies in a linear manner through the machine from station to station.
摘要翻译： 机器可以包括多个站，例如用于执行开放式容器主体的渐进式缩颈。 可以提供一种输送机，用于以线性方式通过机器从站到站索引开放式容器体。
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公开(公告)号：US20050033189A1
公开(公告)日：2005-02-10
申请号：US10912838
申请日：2004-08-06
申请人： Rollin McCraty , Michael Atkinson , Doc Childre
发明人： Rollin McCraty , Michael Atkinson , Doc Childre
IPC分类号： A61B5/0476 , A61B5/053 , A61B5/16 , A61B5/04
CPC分类号： A61B5/02405 , A61B5/0476 , A61B5/0531 , A61B5/16 , A61B5/165 , A61B5/4035 , A61B5/486
摘要： Systems and methods for electrophysiological detection and measurement of intuition are disclosed. In one embodiment, one or more electrophysiological properties of one or more individuals are monitored and used as an indication of a future event. In one embodiment, the electrophysiological property may include heart rate variability, brain wave activity, respiration pattern, skin conductance level, etc. In another embodiment, a signal averaging technique is used to generate a waveform that may be used as an indicator of future events.
摘要翻译： 公开了用于电生理检测和直观测量的系统和方法。 在一个实施例中，监测一个或多个个体的一个或多个电生理特性并用作未来事件的指示。 在一个实施例中，电生理特性可以包括心率变异性，脑波活动，呼吸模式，皮肤电导水平等。在另一个实施例中，使用信号平均技术来产生可用作未来事件的指标的波形 。
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6.发明申请Apparatuses for Transportation of Disc in Connection with Recording Data and Apparatus for Such Recording 审中-公开与记录数据相关的盘的运输装置和用于这种记录的装置公开(公告)号：US20090193446A1
公开(公告)日：2009-07-30
申请号：US12021787
申请日：2008-01-29
申请人： Gary Temush , Michael Atkinson , Av Utukuri , Nick Molo , Anthony Gussin , Ted Chen , Jonathan Clarke
发明人： Gary Temush , Michael Atkinson , Av Utukuri , Nick Molo , Anthony Gussin , Ted Chen , Jonathan Clarke
IPC分类号： G11B17/03
CPC分类号： G11B17/10 , G11B17/056
摘要： An apparatus for the transport of discs for duplication of data onto the discs. The apparatus may include a transportation mechanism, control device, power module and optionally a disc recording mechanism and housing. The transportation mechanism may include an arm, and one or more gear assemblies. Further, the apparatus may also include a drawer device and a plurality of disc holders.
摘要翻译： 一种用于传输用于将数据复制到盘上的盘的装置。 该装置可以包括运输机构，控制装置，功率模块和可选的盘记录机构和壳体。 输送机构可以包括臂和一个或多个齿轮组件。 此外，该装置还可以包括抽屉装置和多个盘保持器。
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7.发明申请Amino Acid Vitamin Ester Compositions for Controlled Delivery of Pharmaceutically Active Compounds 有权用于控制药物活性化合物递送的氨基酸维生素酯组合物公开(公告)号：US20090023678A1
公开(公告)日：2009-01-22
申请号：US12171353
申请日：2008-07-11
IPC分类号： A61K31/7076 , A61K47/16 , A61K31/44 , A61K31/713 , A61K47/12 , A61K31/7052
CPC分类号： A61K45/06 , A61K8/67 , A61K31/198 , A61K31/223 , A61K31/59 , A61K31/7088 , A61K2300/00
摘要： The invention relates to pharmaceutical compositions that provide sustained-release of a pharmaceutically active compound and to methods of treating or preventing a condition in an animal by administering the pharmaceutical compositions to the animal. When the pharmaceutical compositions are administered to an animal by injection, they form a drug depot that releases the pharmaceutically active compound over time. The pharmaceutical compositions can also be administered orally.
摘要翻译： 本发明涉及通过向动物施用药物组合物来提供药物活性化合物的持续释放的药物组合物和治疗或预防动物病症的方法。 当通过注射将药物组合物施用于动物时，它们形成随时间释放药物活性化合物的药物贮库。 药物组合物也可以口服给药。
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公开(公告)号：US20070270668A1
公开(公告)日：2007-11-22
申请号：US11881171
申请日：2007-07-25
申请人： Doc Childre , Rollin McCraty , Michael Atkinson , David Joffe
发明人： Doc Childre , Rollin McCraty , Michael Atkinson , David Joffe
IPC分类号： A61B5/00
CPC分类号： A61B5/0452 , A61B5/02405 , A61B5/16 , A61B5/4035 , A61B5/486
摘要： A coherence value or category for an animal subject is calculated, and a corresponding coherence indication is provided to a human subject. In one embodiment, the beat-to-beat changes in the animal subject's heart rate is monitored, and used to calculate a coherence value, which may be representative of a coherence category. The coherence value may be determined by the power distribution of the heart rate variability data for the animal subject. In another embodiment, the degree of synchronization between an animal subject's coherence and an associated human subject's coherence may be determined and provided as feedback.
摘要翻译： 计算动物受试者的相干值或类别，并向人类对象提供对应的相干指示。 在一个实施例中，监测动物受试者的心率的搏动到搏动的变化，并且用于计算可以代表相干类别的相干值。 相干值可以由动物对象的心率变异性数据的功率分布来确定。 在另一个实施例中，动物受试者的一致性和相关的人类受试者的一致性之间的同步程度可以被确定并提供为反馈。
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公开(公告)号：US20120034710A1
公开(公告)日：2012-02-09
申请号：US13198092
申请日：2011-08-04
IPC分类号： G01N33/577 , H01J49/26
CPC分类号： G01N33/74 , C07K16/26 , G01N33/543 , G01N33/545 , G01N33/577 , G01N33/6848 , G01N2333/58 , G01N2800/32 , G01N2800/325 , G01N2800/50 , G01N2800/52 , G01N2800/7019
摘要： A method for determining the amount of NT-proBNP in blood samples from animals. The method includes detecting degradation products of NT-proBNP by various methods, including using antibodies, kits and device.
摘要翻译： 一种确定动物血样中NT-proBNP量的方法。 该方法包括通过各种方法检测NT-proBNP的降解产物，包括使用抗体，试剂盒和装置。
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公开(公告)号：US08096156B2
公开(公告)日：2012-01-17
申请号：US11980283
申请日：2007-10-29
申请人： Christopher J. Olson , Harold Cook, Jr. , Michael Atkinson , Randy Worwag , Peter Kubisa , Chris Reynolds , Larry Patchen
发明人： Christopher J. Olson , Harold Cook, Jr. , Michael Atkinson , Randy Worwag , Peter Kubisa , Chris Reynolds , Larry Patchen
CPC分类号： B23Q7/02 , B21D51/2615 , B21D51/2692
摘要： Apparatus and method for forming (e.g. die necking) open ends of open-ended metal container bodies. An exemplary embodiment provides a number of movable holders for container bodies that move the container bodies along a path extending through the apparatus. A motor advances the holders and container bodies along the path in steps with pauses between each step. Each step advances one or more container bodies (and preferably two or more). One or more groups of work stations positioned adjacent to the path provides tool sets for carrying out a forming operation on one (and preferably two or more) container bodies simultaneously. Individual container bodies, or more preferably groups of two or more, are subjected to one or more forming operations during passage along the path (preferably the periphery of one or more star wheels).
摘要翻译： 用于形成（例如模头颈缩）开放式金属容器体的开口端的装置和方法。 示例性实施例提供了用于容器主体的多个可移动保持器，其沿着延伸穿过设备的路径移动容器主体。 电机沿着路径逐步推进保持器和容器主体，并在每个步骤之间暂停。 每个步骤前进一个或多个容器体（优选两个或更多个）。 与路径相邻设置的一组或多组工作台提供了用于在一个（优选两个或更多个）容器主体上同时进行成形操作的工具组。 在通过路径（优选一个或多个星形轮的周边）的过程中，单独的容器体，或者更优选两个或更多个的组经受一个或多个成形操作。
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