公开(公告)号：US08543354B2

公开(公告)日：2013-09-24

申请号：US12914969

申请日：2010-10-28

申请人： Ying Luo ,  Rebecca K. Gottlieb ,  Meena Ramachandran ,  Chia-Hung Chiu ,  Nandita Dangui-Patel ,  Michael Kremliovsky ,  Jefferson Rose

发明人： Ying Luo ,  Rebecca K. Gottlieb ,  Meena Ramachandran ,  Chia-Hung Chiu ,  Nandita Dangui-Patel ,  Michael Kremliovsky ,  Jefferson Rose

IPC分类号： G06F17/18

CPC分类号： G01N33/66 ,  A61B5/0017 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7207

摘要： Disclosed are methods, apparatuses, etc. for glucose sensor signal stability analysis. In certain example embodiments, a series of samples of at least one sensor signal that is responsive to a blood glucose level of a patient may be obtained. Based at least partly on the series of samples, at least one metric may be determined to assess an underlying trend of a change in responsiveness of the at least one sensor signal to the blood glucose level of the patient over time. A reliability of the at least one sensor signal to respond to the blood glucose level of the patient may be assessed based at least partly on the at least one metric assessing an underlying trend. Other example embodiments are disclosed herein.

公开(公告)号：US20110320166A1

公开(公告)日：2011-12-29

申请号：US12914969

申请日：2010-10-28

申请人： Ying Luo ,  Rebecca K. Gottlieb ,  Meena Ramachandran ,  Chia-Hung Chiu ,  Nandita Dangui-Patel ,  Michael Kremliovsky ,  Jefferson Rose

发明人： Ying Luo ,  Rebecca K. Gottlieb ,  Meena Ramachandran ,  Chia-Hung Chiu ,  Nandita Dangui-Patel ,  Michael Kremliovsky ,  Jefferson Rose

IPC分类号： G06F19/00 ,  G06F17/18

CPC分类号： G01N33/66 ,  A61B5/0017 ,  A61B5/002 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7207

摘要： Disclosed are methods, apparatuses, etc. for glucose sensor signal stability analysis. In certain example embodiments, a series of samples of at least one sensor signal that is responsive to a blood glucose level of a patient may be obtained. Based at least partly on the series of samples, at least one metric may be determined to assess an underlying trend of a change in responsiveness of the at least one sensor signal to the blood glucose level of the patient over time. A reliability of the at least one sensor signal to respond to the blood glucose level of the patient may be assessed based at least partly on the at least one metric assessing an underlying trend. Other example embodiments are disclosed herein.

摘要翻译： 公开了用于葡萄糖传感器信号稳定性分析的方法，装置等。 在某些示例性实施例中，可以获得响应于患者的血糖水平的至少一个传感器信号的一系列样本。 至少部分地基于一系列样本，可以确定至少一个度量以评估至少一个传感器信号对患者随着时间的血糖水平的响应性的变化的潜在趋势。 可以至少部分地基于评估潜在趋势的至少一个度量来评估至少一个传感器信号对患者的血糖水平的响应的可靠性。 本文公开了其它示例性实施例。

公开(公告)号：US09215995B2

公开(公告)日：2015-12-22

申请号：US13165061

申请日：2011-06-21

申请人： Rebecca K. Gottlieb ,  Chia-Hung Chiu ,  Meena Ramachandran ,  Nandita Dangui-Patel ,  Jefferson Rose ,  Ashwin K. Rao ,  Hsifu Wang ,  Ying Luo

发明人： Rebecca K. Gottlieb ,  Chia-Hung Chiu ,  Meena Ramachandran ,  Nandita Dangui-Patel ,  Jefferson Rose ,  Ashwin K. Rao ,  Hsifu Wang ,  Ying Luo

IPC分类号： A61B5/05 ,  A61B5/1486 ,  A61B5/145 ,  C12Q1/00 ,  A61B5/00 ,  G01N27/30

CPC分类号： A61B5/1486 ,  A61B5/0017 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/726 ,  C12Q1/001 ,  G01N27/307

摘要： Embodiments of the invention provide amperometric analyte sensors having multiple related structural elements (e.g. sensor arrays comprising a working, counter and reference electrode) and algorithms designed for use with such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

摘要翻译： 本发明的实施例提供了具有多个相关结构元件（例如包括工作，计数器和参考电极的传感器阵列）和被设计用于这种传感器的算法的电流分析物传感器。 尽管可以在多种情况下使用创新的实施例，但是本发明的典型实施例包括用于糖尿病管理的葡萄糖传感器。

公开(公告)号：US20110319734A1

公开(公告)日：2011-12-29

申请号：US13165061

申请日：2011-06-21

申请人： Rebecca K. Gottlieb ,  Chia-Hung Chiu ,  Meena Ramachandran ,  Nandita Dangui-Patel ,  Jefferson Rose ,  Ashwin K. Rao ,  Hsifu Wang ,  Ying Luo

发明人： Rebecca K. Gottlieb ,  Chia-Hung Chiu ,  Meena Ramachandran ,  Nandita Dangui-Patel ,  Jefferson Rose ,  Ashwin K. Rao ,  Hsifu Wang ,  Ying Luo

IPC分类号： A61B5/145

CPC分类号： A61B5/1486 ,  A61B5/0017 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/726 ,  C12Q1/001 ,  G01N27/307

摘要： Embodiments of the invention provide amperometric analyte sensors having multiple related structural elements (e.g. sensor arrays comprising a working, counter and reference electrode) and algorithms designed for use with such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

摘要翻译： 本发明的实施例提供了具有多个相关结构元件（例如包括工作，计数器和参考电极的传感器阵列）和被设计用于这种传感器的算法的电流分析物传感器。 尽管可以在多种情况下使用创新的实施例，但是本发明的典型实施例包括用于糖尿病管理的葡萄糖传感器。

公开(公告)号：US20120283538A1

公开(公告)日：2012-11-08

申请号：US13102390

申请日：2011-05-06

申请人： Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

发明人： Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

IPC分类号： A61B5/1468

CPC分类号： A61B5/14735 ,  A61B5/14532 ,  G01N27/3272

摘要： Embodiments of the invention provide analyte sensors and sensor systems such as amperometric glucose sensors used in the management of diabetes as well as optimized methods for monitoring analytes using such sensors and sensor systems.

摘要翻译： 本发明的实施方案提供分析物传感器和传感器系统，例如用于糖尿病管理的电流葡萄糖传感器以及使用这种传感器和传感器系统监测分析物的优化方法。

公开(公告)号：US09008744B2

公开(公告)日：2015-04-14

申请号：US13102390

申请日：2011-05-06

申请人： Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

发明人： Jefferson Rose ,  Ashwin K. Rao ,  Ning Yang ,  Chia-Hung Chiu ,  Ying Luo ,  Rebecca K. Gottlieb

IPC分类号： A61B5/05 ,  A61B5/1473 ,  A61B5/145 ,  G01N27/327

CPC分类号： A61B5/14735 ,  A61B5/14532 ,  G01N27/3272

摘要： Embodiments of the invention provide analyte sensors and sensor systems such as amperometric glucose sensors used in the management of diabetes as well as optimized methods for monitoring analytes using such sensors and sensor systems.

摘要翻译： 本发明的实施方案提供分析物传感器和传感器系统，例如用于糖尿病管理的电流葡萄糖传感器以及使用这种传感器和传感器系统监测分析物的优化方法。

公开(公告)号：US20110230735A1

公开(公告)日：2011-09-22

申请号：US13047431

申请日：2011-03-14

申请人： Katherine T. Wolfe ,  Ameya S. Kantak ,  Eric Allan Larson ,  Daniel E. Pesantez ,  Dongjuan Xi ,  Chia-Hung Chiu ,  Rajiv Shah

发明人： Katherine T. Wolfe ,  Ameya S. Kantak ,  Eric Allan Larson ,  Daniel E. Pesantez ,  Dongjuan Xi ,  Chia-Hung Chiu ,  Rajiv Shah

IPC分类号： A61B5/145 ,  G01N27/26 ,  G01N33/50

CPC分类号： A61B5/14865 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/6848

摘要： Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.

摘要翻译： 本发明的实施例提供了具有优化的元件和/或元件构造的分析物传感器以及用于制造和使用这种传感器的方法。 本发明的典型实施方案包括用于治疗糖尿病的葡萄糖传感器。

公开(公告)号：US10448872B2

公开(公告)日：2019-10-22

申请号：US13047431

申请日：2011-03-14

申请人： Katherine T. Wolfe ,  Ameya S. Kantak ,  Eric Allan Larson ,  Daniel E. Pesantez ,  Dongjuan Xi ,  Chia-Hung Chiu ,  Rajiv Shah

发明人： Katherine T. Wolfe ,  Ameya S. Kantak ,  Eric Allan Larson ,  Daniel E. Pesantez ,  Dongjuan Xi ,  Chia-Hung Chiu ,  Rajiv Shah

IPC分类号： A61B5/1486 ,  A61B5/145 ,  A61B5/00

摘要： Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US20120170786A1

公开(公告)日：2012-07-05

申请号：US12983332

申请日：2011-01-03

申请人： Hsiang-Chih Yu ,  Chia-Hung Chiu

发明人： Hsiang-Chih Yu ,  Chia-Hung Chiu

IPC分类号： H04R1/10

CPC分类号： H04R5/033 ,  H04R17/00

摘要： A piezoelectric ceramic loudspeaker headphone structure includes a positioning frame, a steel sheet and a vibrating member. A step portion is disposed in an inner edge at the rear of the positioning frame. The steel sheet has an area approximately equal to that of the positioning frame and is disposed with a sound-making member stacked by a plurality of ceramic material layers. A lead wire is welded to the sound-making member. The vibrating member is a sheet body and has an area approximately equal to that of the step portion of the positioning frame. The steel sheet is disposed at a front edge of the positioning frame. The vibrating member is embedded in the step portion of the positioning frame, and thus a sound-making module is formed. The sound-making module is assembled to a headphone, and after the sound-making member receives an audio signal, a sound is guided out through response of the vibrating member. Therefore, the headphone is free of magnetism without influencing electronic products such as i-pad, i-phone, mobile phones or notebook computers, and is thinned due to omitting voice coils, which thus can be conveniently carried along.

摘要翻译： 压电陶瓷扬声器耳机结构包括定位框架，钢板和振动构件。 台阶部分设置在定位框架后部的内边缘。 钢板的面积大致等于定位框架的面积，配置有由多个陶瓷材料层堆叠的声音构件。 引线焊接到声音构件。 振动构件是片体，并且具有与定位框架的台阶部分大致相等的区域。 钢板设置在定位框架的前缘。 振动部件嵌入定位架的台阶部，形成发声模块。 声音模块被组装到耳机，并且在声音构件接收音频信号之后，通过振动构件的响应引导声音。 因此，耳机没有磁性而不影响诸如i-pad，i-phone，手机或笔记本电脑的电子产品，并且由于省略音圈而变薄，因此可以方便地携带。

公开(公告)号：US08394463B1

公开(公告)日：2013-03-12

申请号：US12692001

申请日：2010-01-22

申请人： Chia-Hung Chiu ,  Marco Sillus ,  Barry Pham ,  Ly Phou ,  Gil Bruso ,  Christopher R. Enegren ,  Heath Jensen ,  Michael Paul Minor ,  Rajiv Shah

发明人： Chia-Hung Chiu ,  Marco Sillus ,  Barry Pham ,  Ly Phou ,  Gil Bruso ,  Christopher R. Enegren ,  Heath Jensen ,  Michael Paul Minor ,  Rajiv Shah

IPC分类号： C08J7/16

CPC分类号： G01N27/3272 ,  C08J3/246

摘要： Embodiments of the invention provide methods of crosslinking various compounds and materials made by these methods. Materials made by embodiments of the invention include glucose sensors used in the management of diabetes.

摘要翻译： 本发明的实施方案提供了交联通过这些方法制备的各种化合物和材料的方法。 由本发明的实施方案制备的材料包括用于治疗糖尿病的葡萄糖传感器。