公开(公告)号：US20060240408A1

公开(公告)日：2006-10-26

申请号：US11257833

申请日：2005-10-25

申请人： Yoon-kyoung Cho ,  Sook-young Kim ,  Jin-tae Kim ,  Kyu-sang Lee

发明人： Yoon-kyoung Cho ,  Sook-young Kim ,  Jin-tae Kim ,  Kyu-sang Lee

IPC分类号： C12Q1/70 ,  C12Q1/68

CPC分类号： C12N15/1006 ,  C12Q1/6806 ,  C12Q1/70 ,  Y10S977/924 ,  C12Q2563/155 ,  C12Q2523/308

摘要： Provided is a method of purifying a target substance using silver nanoparticles. The method includes: mixing a sample containing molecules having a thiol group with the silver nanoparticles to obtain a complex of the molecules having the thiol group with the silver nanoparticles; and isolating and removing the complex from the mixture. By using the purification method, PCR amplifiable DNAs can be rapidly purified, and thus, the method can be very efficiently applied to lab-on-chip (LOC).

摘要翻译： 提供了使用银纳米粒子来净化目标物质的方法。 该方法包括：将含有硫醇基的分子的样品与银纳米颗粒混合，得到具有硫醇基的分子与银纳米颗粒的络合物; 并从混合物中分离并除去络合物。 通过使用纯化方法，可以快速纯化PCR扩增的DNA，因此该方法可以非常有效地应用于片上实验（LOC）。

公开(公告)号：US07364857B2

公开(公告)日：2008-04-29

申请号：US11257833

申请日：2005-10-25

申请人： Yoon-kyoung Cho ,  Sook-young Kim ,  Jin-tae Kim ,  Kyu-sang Lee

发明人： Yoon-kyoung Cho ,  Sook-young Kim ,  Jin-tae Kim ,  Kyu-sang Lee

IPC分类号： C12Q1/68

CPC分类号： C12N15/1006 ,  C12Q1/6806 ,  C12Q1/70 ,  Y10S977/924 ,  C12Q2563/155 ,  C12Q2523/308

摘要： Provided is a method of purifying a target substance using silver nanoparticles. The method includes: mixing a sample containing molecules having a thiol group with the silver nanoparticles to obtain a complex of the molecules having the thiol group with the silver nanoparticles; and isolating and removing the complex from the mixture. By using the purification method, PCR amplifiable DNAs can be rapidly purified, and thus, the method can be very efficiently applied to lab-on-chip (LOC).

摘要翻译： 提供了使用银纳米粒子来净化目标物质的方法。 该方法包括：将含有硫醇基的分子的样品与银纳米颗粒混合，得到具有硫醇基的分子与银纳米颗粒的络合物; 并从混合物中分离并除去络合物。 通过使用纯化方法，可以快速纯化PCR扩增的DNA，因此该方法可以非常有效地应用于片上实验（LOC）。

公开(公告)号：US08137523B2

公开(公告)日：2012-03-20

申请号：US11754523

申请日：2007-05-29

申请人： Yoon-kyoung Cho ,  Su-hyeon Kim ,  Chin-sung Park ,  Kyu-sang Lee ,  Jeong-gun Lee

发明人： Yoon-kyoung Cho ,  Su-hyeon Kim ,  Chin-sung Park ,  Kyu-sang Lee ,  Jeong-gun Lee

IPC分类号： G01N27/26 ,  G01N27/447

CPC分类号： B03C5/005 ,  B03C5/026 ,  B03C2201/26

摘要： An apparatus separating a polarizable analyte using dielectrophoresis includes a vessel including a membrane having a plurality of nano- to micro-sized pores, the membrane disposed inside the vessel, electrodes generating spatially non-uniform electric fields in the nano- to micro-sized pores of the membrane when an AC voltage is applied to the electrodes, and a power source applying the AC voltage to the electrodes, wherein a sectional area of the pores varies along a depth of the pores. A method of separating a polarizable material uses the apparatus.

摘要翻译： 使用介电电泳分离可极化分析物的装置包括容器，其包括具有多个纳米至微米尺寸孔的膜，所述膜设置在容器内部，电极在纳米至微孔中产生空间上不均匀的电场 当向电极施加AC电压时，将膜施加到膜上，并且向电极施加AC电压的电源，其中孔的截面积沿着孔的深度而变化。 分离可极化材料的方法使用该装置。

公开(公告)号：US08357957B2

公开(公告)日：2013-01-22

申请号：US12912191

申请日：2010-10-26

申请人： Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

发明人： Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

IPC分类号： H01L29/78

CPC分类号： G01N33/54373 ,  C12Q1/6825 ,  G01N27/4145

摘要： Provided are a FET-based sensor for detecting an ionic material, an ionic material detecting device including the FET-based sensor, and a method of detecting an ionic material using the FET-based sensor. The FET-based sensor includes: a sensing chamber including a reference electrode and a plurality of sensing FETs; and a reference chamber including a reference electrode and a plurality of reference FETs. The method includes: flowing a first solution into and out of the sensing chamber and the reference chamber of the FET-based sensor; flowing a second solution expected to contain an ionic material into and out of the sensing chamber while continuously flowing the first solution into and out of the reference chamber; measuring a current in a channel region between the source and drain of each of the sensing and reference FETs; and correcting the current of the sensing FETs.

摘要翻译： 提供了一种用于检测离子材料的基于FET的传感器，包括基于FET的传感器的离子材料检测装置，以及使用基于FET的传感器检测离子材料的方法。 基于FET的传感器包括：感测室，包括参考电极和多个感测FET; 以及包括参考电极和多个参考FET的参考室。 该方法包括：使第一溶液流入和流出基于FET的传感器的感测室和参考室; 使预期含有离子材料的第二溶液流入和流出感测室，同时使第一溶液持续流入和移出参考室; 测量每个感测和参考FET的源极和漏极之间的沟道区域中的电流; 并校正感测FET的电流。

公开(公告)号：US07859029B2

公开(公告)日：2010-12-28

申请号：US11621191

申请日：2007-01-09

申请人： Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

发明人： Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

IPC分类号： H01L29/78

CPC分类号： G01N33/54373 ,  C12Q1/6825 ,  G01N27/4145

摘要： Provided are a FET-based sensor for detecting an ionic material, an ionic material detecting device including the FET-based sensor, and a method of detecting an ionic material using the FET-based sensor. The FET-based sensor includes: a sensing chamber including a reference electrode and a plurality of sensing FETs; and a reference chamber including a reference electrode and a plurality of reference FETs. The method includes: flowing a first solution into and out of the sensing chamber and the reference chamber of the FET-based sensor; flowing a second solution expected to contain an ionic material into and out of the sensing chamber while continuously flowing the first solution into and out of the reference chamber; measuring a current in a channel region between the source and drain of each of the sensing and reference FETs; and correcting the current of the sensing FETs.

摘要翻译： 提供了一种用于检测离子材料的基于FET的传感器，包括基于FET的传感器的离子材料检测装置，以及使用基于FET的传感器检测离子材料的方法。 基于FET的传感器包括：感测室，包括参考电极和多个感测FET; 以及包括参考电极和多个参考FET的参考室。 该方法包括：使第一溶液流入和流出基于FET的传感器的感测室和参考室; 使预期含有离子材料的第二溶液流入和流出感测室，同时使第一溶液持续流入和移出参考室; 测量每个感测和参考FET的源极和漏极之间的沟道区域中的电流; 并校正感测FET的电流。

公开(公告)号：US08293591B2

公开(公告)日：2012-10-23

申请号：US11733539

申请日：2007-04-10

申请人： Jeo-young Shim ,  Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Yeon-ja Cho ,  Chang-eun Yoo

发明人： Jeo-young Shim ,  Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Yeon-ja Cho ,  Chang-eun Yoo

IPC分类号： H01L31/00

CPC分类号： H01L29/78 ,  G01N27/4145

摘要： A field effect transistor for detecting an analyte having a thiol group includes a substrate, a source region and a drain region formed apart from each other on the substrate, the source region and the drain region being doped such that a polarity of the source and drain region is opposite to a polarity of the substrate, a channel region disposed between the source region and the drain region, an insulating layer formed of an electrically insulating material and disposed on the channel region, a gold layer disposed on the insulating layer and a reference electrode disposed apart from the gold layer.

摘要翻译： 用于检测具有硫醇基的分析物的场效应晶体管包括在衬底上彼此分开形成的衬底，源极区和漏极区，源极区和漏极区被掺杂，使得源极和漏极的极性 区域与基板的极性相反，设置在源极区域和漏极区域之间的沟道区域，由电绝缘材料形成并设置在沟道区域上的绝缘层，设置在绝缘层上的金层和参考 电极与金层分开设置。

公开(公告)号：US07914996B2

公开(公告)日：2011-03-29

申请号：US12627022

申请日：2009-11-30

申请人： Kyung-hee Park ,  Kyu-sang Lee ,  Yeon-su Lee ,  Jae-Heup Kim ,  Yeon-a Park ,  Ji-young Cho ,  Ok-kyoung Son ,  Byung-chul Kim ,  Min-sun Kim

发明人： Kyung-hee Park ,  Kyu-sang Lee ,  Yeon-su Lee ,  Jae-Heup Kim ,  Yeon-a Park ,  Ji-young Cho ,  Ok-kyoung Son ,  Byung-chul Kim ,  Min-sun Kim

IPC分类号： C07H21/04 ,  C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/156 ,  C12Q2600/172

摘要： Provided is a polynucleotide including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID NOS: 1-12 and including a nucleotide at position 101 of the nucleotide sequence, or a complementary polynucleotide thereof.

摘要翻译： 提供了包含选自SEQ ID NO：1-12的核苷酸序列并且包含核苷酸序列的101位的核苷酸的核苷酸序列的至少10个连续核苷酸或其互补多核苷酸的多核苷酸。

公开(公告)号：US07269108B2

公开(公告)日：2007-09-11

申请号：US10717599

申请日：2003-11-21

申请人： Kyu-sang Lee

发明人： Kyu-sang Lee

IPC分类号： G11B15/05

CPC分类号： G11B19/06 ,  G11B27/105 ,  G11B27/36 ,  G11B2220/213 ,  G11B2220/2545 ,  G11B2220/2562

摘要： A disc drive, and method of automatically ejecting a disc from a disc player. The method comprises selecting a main title from a plurality of titles recorded on the disc and storing a playback time of the main title in a memory, and determining whether the main title is playing, or has played, back. Upon determining that the main title is playing or has played back, the playback time of the main title is compared with a time required for playback of the main title stored in the memory and determining whether playback of the main title has terminated. Upon determining that playback of the main title is terminated, the disc is ejected by driving an unloading device.

摘要翻译： 磁盘驱动器，以及自动从光盘播放器弹出光盘的方法。 该方法包括从记录在盘上的多个标题中选择主标题，并将主标题的播放时间存储在存储器中，以及确定主标题是播放还是播放。 在确定主标题正在播放或已经重放时，将主标题的回放时间与存储在存储器中的主标题的回放所需的时间进行比较，并确定主标题的回放是否已经终止。 在确定主标题的播放被终止时，通过驱动卸载装置来弹出该盘。

公开(公告)号：US08035175B2

公开(公告)日：2011-10-11

申请号：US11613258

申请日：2006-12-20

申请人： Jeo-young Shim ,  Kyu-sang Lee ,  Kyu-tae Yoo ,  Won-seok Chung

发明人： Jeo-young Shim ,  Kyu-sang Lee ,  Kyu-tae Yoo ,  Won-seok Chung

IPC分类号： H01L27/14

CPC分类号： G01N27/4145

摘要： A field effect transistor for detecting ionic material and a method of detecting ionic material using the field effect transistor. The field effect transistor for detecting ionic material includes a substrate formed of a semiconductor material, a source region and a drain region spaced apart from each other in the substrate and doped with an opposite conductivity type to that of the substrate, a channel region interposed between the source region and the drain region, an insulating layer disposed on the channel region and formed of an electrically insulating material, a first reference electrode disposed at an edge of the upper portion of the insulating layer and a second reference electrode disposed to be spaced apart from the insulating layer.

摘要翻译： 用于检测离子材料的场效应晶体管和使用场效应晶体管检测离子材料的方法。 用于检测离子材料的场效应晶体管包括由衬底形成的衬底，源极区和漏极区，在衬底中彼此间隔开并且掺杂有与衬底相反的导电类型，沟道区介于 源极区域和漏极区域，设置在沟道区域上并由电绝缘材料形成的绝缘层，设置在绝缘层的上部的边缘处的第一参考电极和设置成间隔开的第二参考电极 从绝缘层。

公开(公告)号：US20100169107A1

公开(公告)日：2010-07-01

申请号：US12623893

申请日：2009-11-23

申请人： Tae-jin Ahn ,  Kyu-sang Lee ,  Dae-soon Son ,  Kyung-hee Park

发明人： Tae-jin Ahn ,  Kyu-sang Lee ,  Dae-soon Son ,  Kyung-hee Park

IPC分类号： G06F17/30 ,  G06Q99/00 ,  G06F21/00

CPC分类号： G06Q50/22 ,  G16B50/00 ,  G16H10/60

摘要： Provided are a method and an apparatus for managing data indicating personal genome data. The method includes obtaining property information of a first personal genome data, which indicates genome information of an individual, by analyzing a first personal genome data, and generating integrated data by integrating the first personal genome data and a second personal genome data indicating genome data of the individual based on the obtained property information.

摘要翻译： 提供了一种用于管理表示个人基因组数据的数据的方法和装置。 该方法包括：通过分析第一个人基因组数据来获得指示个体的基因组信息的第一个人基因组数据的属性信息，以及通过整合第一个人基因组数据和指示基因组数据的第二个人基因组数据来生成综合数据 个人基于获得的财产信息。