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公开(公告)号：US4810790A
公开(公告)日：1989-03-07
申请号：US106423
申请日：1987-10-09
IPC分类号： C07D239/54 , C07D239/553
CPC分类号： C07D239/553
摘要： A novel 5-fluorouracil derivative of the formula: ##STR1## wherein R.sup.1 is a fluorine-containing C.sub.1 -C.sub.10 organic group which optionally contains sulfur, oxygen and/or nitrogen. The novel 5-fluorouracil derivative is useful as a carcinostatic substance, which has a high carcinostatic activity but which is less toxicity against digestive tract and causes less autonomic imbalance than other known 5-fluorouracil derivatives.
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公开(公告)号：US4876245A
公开(公告)日：1989-10-24
申请号：US136125
申请日：1987-12-21
IPC分类号： C07H17/08
CPC分类号： C07H17/08
摘要： A fluorine-containing macrolide compound of the formula: ##STR1## wherein R.sup.1 is hydroxy or --OR (wherein R is C.sub.1 -C.sub.5 alkyl),R.sup.2 is hydrogen or hydroxy, orR.sup.1 and R.sup.2 together form a cyclic residue of the formula: ##STR2## (wherein R' and R" are independently hydrogen or C.sub.1 -C.sub.5 alkyl), ##STR3## when R.sup.4 is hydrogen or C.sub.1 -C.sub.5 alkyl, or R.sup.3 is ##STR4## when R.sup.4 is ##STR5## (wherein Ph is phenyl), R.sup.5 is hydrogen or C.sub.1 -C.sub.5 alkyl, andR.sup.6 is hydrogen or methyland an antimicrobial agent containing the fluorine-containing macrolide compound (I) as an effective component.
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3.发明申请公开(公告)号：US20050021908A1
公开(公告)日：2005-01-27
申请号：US10783283
申请日：2004-02-20
申请人： Shotaro Ohno , Toshihiko Kawano , Takashi Kitayama , Toshiyuki Haruma , Akinori Ono , Yuichiro Nagashima
发明人： Shotaro Ohno , Toshihiko Kawano , Takashi Kitayama , Toshiyuki Haruma , Akinori Ono , Yuichiro Nagashima
CPC分类号： G06F3/0634 , G06F3/0605 , G06F3/067 , G06F11/2069
摘要： Pairs are formed from a plurality of dispersed volumes and copying between the volumes is conducted by a series of remote operations from a management server. A management server 10 instructs the generation of configuration setting files 23, 30 to host computers 20, 30 selected so as to form copy pairs. If the configuration setting files are generated by host agents 21, 31, the management server 10 instructs copy start to a host computer 20 having a primary volume. The host agent 21 generates a prescribed command via a copy pair control module 22 and causes a storage subsystem 40 to execute copying between the volumes. When copying is completed, the management server 10 acquires the newest storage configuration information from the storage subsystem 40 and updates configuration information DB12.
摘要翻译： 由多个分散的卷形成对，并且通过来自管理服务器的一系列远程操作来进行卷之间的复制。 管理服务器10指示生成配置设置文件23,30以主机选择以形成副本对的计算机20,30。 如果配置设置文件由主机代理21,31生成，则管理服务器10指示复制开始到具有主卷的主计算机20。 主机代理21通过复制对控制模块22生成规定的命令，并使存储子系统40在卷之间执行复制。 当复制完成时，管理服务器10从存储子系统40获取最新的存储配置信息，并更新配置信息DB12。
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4.发明授权DA conversion apparatus to reduce transient noise upon switching of analog signals 失效DA转换装置，以在模拟信号切换时减少瞬态噪声公开(公告)号：US06201490B1
公开(公告)日：2001-03-13
申请号：US09191425
申请日：1998-11-12
IPC分类号： H03M162
CPC分类号： H03M1/0626 , H03M1/70
摘要： A D/A conversion apparatus includes a DSP which receives and converts input digital data with different conversion factors, to generate a plurality of digital data having different levels, selects one of the plurality of the generated digital data, depending upon the signal quality of the input digital data, while attenuating the other digital data to be lower than a predetermined noise level. A plurality of D/A converting devices convert the respective generated digital data into corresponding analog signals. A re-converting device converts the level of each of the analog signals into an original level, based on a corresponding one of the conversion factors with which the input digital data is converted by the DSP. An adding device adds the re-converted analog signals. An attenuating device attenuates, in an input stage of the adding device, medium-to-high frequency components of at least one of the analog signals generated by at least one of the D/A converting devices that receives the attenuated digital data, and corresponding to digital data obtained by converting the input digital data with a smaller conversion factor than that of the digital data selected and generated by the DSP.
摘要翻译： AD / A转换装置包括DSP，其接收并转换具有不同转换因子的输入数字数据，以产生具有不同电平的多个数字数据，根据输入的信号质量选择多个生成的数字数据中的一个 数字数据，同时将其他数字数据衰减到低于预定噪声电平。 多个D / A转换装置将各自生成的数字数据转换成相应的模拟信号。 再转换装置根据输入数字数据由DSP转换的转换因数之一，将每个模拟信号的电平转换成原始电平。 添加设备添加重新转换的模拟信号。 衰减装置在加法装置的输入级中衰减由至少一个接收衰减的数字数据的D / A转换装置产生的至少一个模拟信号的中至高频分量，以及对应的 通过以比由DSP选择和产生的数字数据的转换因子更小的转换因子转换输入数字数据而获得的数字数据。
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公开(公告)号：US5233993A
公开(公告)日：1993-08-10
申请号：US794049
申请日：1991-11-19
申请人： Toshihiko Kawano
发明人： Toshihiko Kawano
CPC分类号： G01S15/8979 , G01N29/0609 , G01S15/58 , G01S7/52085 , G01S7/52074
摘要： An ultrasonic diagnostic apparatus operates such that the ultrasonic beam transmission and reception is made in the same scanning direction twice at intervals shorter than the frame rate. A subtraction operation is performed between line data obtained by the successive transmissions and receptions. A subtraction image is formed by subtraction image data obtained by scanning in a plurality of scanning directions.
摘要翻译： 超声波诊断装置的操作使得超声波束发送和接收在相同的扫描方向上以比帧速更短的间隔进行两次。 在通过连续传输获得的线数据和接收之间执行减法运算。 通过在多个扫描方向上扫描获得的减法图像数据形成减法图像。
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公开(公告)号：US09060737B2
公开(公告)日：2015-06-23
申请号：US11913852
申请日：2006-05-09
CPC分类号： A61B8/485 , A61B8/08 , A61B8/14 , G01S7/52042 , G01S7/52071 , G01S7/52073 , G01S7/52074
摘要： An image showing the spatial distribution of the hardness of a tissue of an object to be examined from which the influence of the pressure amount is eliminated is displayed.From ultrasonic tomography data measured by pressing the tissue, a physical quantity relating to the distortion of the tissue at measurement points of the tissue is determined.An elasticity image of the tissue is created according to the physical quantity.The physical quantities at the measurement points are indexed by using the physical quantity in a reference region determined in the elasticity image as a reference, and an indexed elasticity image showing the distribution of the index value is created.
摘要翻译： 显示示出了消除了压力量的影响的被检体的组织的硬度的空间分布的图像。 从通过按压组织测量的超声波断层扫描数据，确定与组织测量点处的组织变形相关的物理量。 根据物理量产生组织的弹性图像。 通过使用在弹性图像中确定的参考区域中的物理量作为参考来对测量点处的物理量进行索引，并且创建表示索引值分布的索引弹性图像。
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7.发明授权Floating type analog-to-digital converter using delay units to achieve a wide dynamic range 失效浮动型模数转换器采用延时单元实现宽动态范围
公开(公告)号：US06104329A
公开(公告)日：2000-08-15
申请号：US98160
申请日：1998-06-16
申请人： Toshihiko Kawano
发明人： Toshihiko Kawano
CPC分类号： H03M3/488
摘要： A floating type analog-to-digital converter which is capable of converting an analog signal into a digital signal in a wide dynamic range, while exhibiting stable frequency characteristics due to the presence of symmetric pre-echo and post-echo in the impulse response waveform. An analog signal level adjusting device adjusts the level of an analog signal with different first gains, so as to generate a plurality of analog signals of different levels for analog-to-digital conversion. A plurality of analog-to-digital converters convert respective ones of the plurality of analog signals generated from the analog signal level adjusting device, into respective digital signals, and output the digital signals. A digital signal level adjusting device adjusts the levels of the digital signals with different second gains corresponding to respective inverses of the first gains, and generates the adjusted digital signals, which are then delayed and generated by a delay device. A switching device selects one of the digital signals generated from the delay device, based on the level of one digital signal selected from the digital signals generated from the plurality of analog-to-digital converters, and generates the selected one digital signal.
摘要翻译： 一种浮动型模数转换器，其能够在宽动态范围内将模拟信号转换成数字信号，同时由于在脉冲响应波形中存在对称的预回波和后回波而呈现稳定的频率特性 。 模拟信号电平调整装置利用不同的第一增益调节模拟信号的电平，以产生用于模数转换的不同电平的多个模拟信号。 多个模数转换器将从模拟信号电平调整装置产生的多个模拟信号中的各个模拟信号转换为相应的数字信号，并输出数字信号。 数字信号电平调整装置利用与第一增益的相应反转相对应的不同的第二增益来调整数字信号的电平，并产生经延迟装置延迟和产生的经调整的数字信号。 开关装置基于从从多个模数转换器产生的数字信号中选择的一个数字信号的电平，选择从延迟装置产生的一个数字信号，并产生所选择的一个数字信号。
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公开(公告)号：US5325859A
公开(公告)日：1994-07-05
申请号：US3623
申请日：1993-01-13
申请人： Ken Ishihara , Toshihiko Kawano
发明人： Ken Ishihara , Toshihiko Kawano
CPC分类号： G01S15/899 , A61B5/0456 , A61B8/06 , A61B8/13 , A61B8/463 , G01S15/8979
摘要： An ultrasonic diagnosis apparatus comprises an ultrasonic wave transmitting/receiving unit for transmitting ultrasonic signals to a subject and receiving reflected echo signals reflected from the subject; a unit for controlling the ultrasonic wave transmitting/receiving unit such that the ultrasonic signals repetitively scan the subject at a predetermined scan period; an image memory unit for storing a plurality of image data pieces; a detection unit for detecting biophysical signals of the subject; a unit for setting a reference timing on the basis of the biophysical signals; an image display unit for displaying an image corresponding to the image data piece being delivered out of the image memory unit, the image display unit displaying the image at a predetermined display unit; a unit for controlling the image memory unit so as to store the plurality of image data pieces based on the reflected echo signals, wherein the plurality of image data pieces respectively correspond to two-dimensional images of the subject at different time points and the time points associated with the plurality of image data pieces are sequentially displaced by a first time interval and in synchronism with the reference timing; and a control unit for controlling the memory unit so as to sequentially deliver the plurality of image data pieces stored in the image memory unit at second time intervals longer than the first time interval during scanning of the ultrasonic signals.
摘要翻译： 超声波诊断装置包括：超声波发送接收部，其向对象发送超声波信号，并接收从被检体反射的反射回波信号; 用于控制所述超声波发射/接收单元的单元，使得所述超声波信号以预定扫描周期重复地扫描所述对象; 图像存储单元，用于存储多个图像数据片; 用于检测所述对象的生物物理信号的检测单元; 基于生物物理信号设定基准定时的单元; 图像显示单元，用于显示与从所述图像存储单元传送出的图像数据片段对应的图像，所述图像显示单元在预定显示单元处显示所述图像; 用于基于反射的回波信号来控制图像存储单元以便存储多个图像数据的单元，其中多个图像数据分别对应于在不同时间点和时间点的对象的二维图像 与所述多个图像数据片段相关联地顺序地移位第一时间间隔并与所述参考时序同步; 以及控制单元，用于控制存储单元，以便在扫描超声波信号期间以比第一时间间隔更长的第二时间间隔顺序地传送存储在图像存储单元中的多个图像数据。
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公开(公告)号：US20090216123A1
公开(公告)日：2009-08-27
申请号：US11913852
申请日：2006-05-09
IPC分类号： A61B8/14
CPC分类号： A61B8/485 , A61B8/08 , A61B8/14 , G01S7/52042 , G01S7/52071 , G01S7/52073 , G01S7/52074
摘要： An image showing the spatial distribution of the hardness of a tissue of an object to be examined from which the influence of the pressure amount is eliminated is displayed.From ultrasonic tomography data measured by pressing the tissue, a physical quantity relating to the distortion of the tissue at measurement points of the tissue is determined.An elasticity image of the tissue is created according to the physical quantity.The physical quantities at the measurement points are indexed by using the physical quantity in a reference region determined in the elasticity image as a reference, and an indexed elasticity image showing the distribution of the index value is created.
摘要翻译： 显示示出了消除了压力量的影响的被检体的组织的硬度的空间分布的图像。 从通过按压组织测量的超声波断层扫描数据，确定与组织测量点处的组织变形相关的物理量。 根据物理量产生组织的弹性图像。 通过使用在弹性图像中确定的参考区域中的物理量作为参考来对测量点处的物理量进行索引，并且创建表示索引值分布的索引弹性图像。
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10.发明申请公开(公告)号：US20080307176A1
公开(公告)日：2008-12-11
申请号：US12050699
申请日：2008-03-18
申请人： Shotaro OHNO , Toshihiko Kawano , Takashi Kitayama , Toshiyuki Haruma , Akinori Ono , Yuichiro Nagashima
发明人： Shotaro OHNO , Toshihiko Kawano , Takashi Kitayama , Toshiyuki Haruma , Akinori Ono , Yuichiro Nagashima
IPC分类号： G06F12/16
CPC分类号： G06F3/0634 , G06F3/0605 , G06F3/067 , G06F11/2069
摘要： Pairs are formed from a plurality of dispersed volumes and copying between the volumes is conducted by a series of remote operations from a management server. A management server 10 instructs the generation of configuration setting files 23, 30 to host computers 20, 30 selected so as to form copy pairs. If the configuration setting files are generated by host agents 21, 31, the management server 10 instructs copy start to a host computer 20 having a primary volume. The host agent 21 generates a prescribed command via a copy pair control module 22 and causes a storage subsystem 40 to execute copying between the volumes. When copying is completed, the management server 10 acquires the newest storage configuration information from the storage subsystem 40 and updates configuration information DB12.
摘要翻译： 由多个分散的卷形成对，并且通过来自管理服务器的一系列远程操作来进行卷之间的复制。 管理服务器10指示生成配置设置文件23,30以主机选择以形成复制对的计算机20,30。 如果配置设置文件由主机代理21,31生成，则管理服务器10指示复制开始到具有主卷的主计算机20。 主机代理21通过复制对控制模块22生成规定的命令，并使存储子系统40在卷之间执行复制。 当复制完成时，管理服务器10从存储子系统40获取最新的存储配置信息，并更新配置信息DB12。
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