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    Combined physiological sensor systems and methods
    1.
    发明授权
    Combined physiological sensor systems and methods 有权
    组合生理传感器系统和方法

    公开(公告)号：US09138183B2

    公开(公告)日：2015-09-22

    申请号：US13020704

    申请日：2011-02-03

    申请人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison

    发明人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison

    IPC分类号： A61B5/00 ,  A61B5/1455 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/16

    CPC分类号： A61B5/02055 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02433 ,  A61B5/14552 ,  A61B5/165 ,  A61B5/6814 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/726

    摘要： A combined physiological sensor and methods for detecting one or more physiological characteristics of a subject are provided. The combined sensor (e.g., a forehead sensor) may be used to detect and/or calculate at least one of a pulse blood oxygen saturation level, a regional blood oxygen saturation level, a respiration rate, blood pressure, an electrical physiological signal (EPS), a pulse transit time (PTT), body temperature associated with the subject, a depth of consciousness (DOC) measurement, any other suitable physiological parameter, and any suitable combination thereof. The combined sensor may include a variety of individual sensors, such as electrodes, optical detectors, optical emitters, temperature sensors, and/or other suitable sensors. The sensors may be advantageously positioned in accordance with a number of different geometries. The combined sensor may also be coupled to a monitoring device, which may receive and/or process one or more output signals from the individual sensors to display information about the medical condition of the subject. In addition, several techniques may be employed to prevent or limit interference between the individual sensors and their associated input and/or output signals.

    摘要翻译： 提供组合的生理传感器和用于检测受试者的一种或多种生理特征的方法。 组合的传感器（例如，前额传感器）可用于检测和/或计算脉搏血氧饱和度水平，区域血氧饱和度水平，呼吸速率，血压，电生理信号（EPS ），脉搏传播时间（PTT），与受试者相关的体温，意识深度（DOC）测量，任何其它合适的生理参数及其任何合适的组合。 组合的传感器可以包括各种单独的传感器，例如电极，光学检测器，光发射器，温度传感器和/或其它合适的传感器。 可以根据多个不同的几何形状有利地定位传感器。 组合的传感器还可以耦合到监视设备，监视设备可以接收和/或处理来自各个传感器的一个或多个输出信号以显示关于对象的医疗状况的信息。 此外，可以采用几种技术来防止或限制各个传感器及其相关的输入和/或输出信号之间的干扰。

    Simultaneous measurement of pulse and regional blood oxygen saturation
    3.
    发明授权
    Simultaneous measurement of pulse and regional blood oxygen saturation 有权
    同时测量脉搏和局部血氧饱和度

    公开(公告)号：US08588878B2

    公开(公告)日：2013-11-19

    申请号：US12944945

    申请日：2010-11-12

    申请人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    发明人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/7203 ,  A61B5/726

    摘要： Methods and systems are provided that allow for the simultaneous calculation of pulse and regional blood oxygen saturation. An oximeter system that includes a sensor with a plurality of emitters and detectors may be used to calculate a pulse and/or regional blood oxygen saturation. A plurality of light signals may be emitted from light emitters. A first light signal may be received at a first light detector and a second light signal may be received at a second light detector. A pulse and/or regional blood oxygen saturation value may be calculated based on the received first and/or second light signals. The pulse and regional blood oxygen saturation values may be calculated substantially simultaneously. The calculated pulse and regional blood oxygen saturation values as well as other blood oxygen saturation values may be displayed simultaneously in a preconfigured portion of a display.

    摘要翻译： 提供了允许同时计算脉搏和局部血氧饱和度的方法和系统。 包括具有多个发射器和检测器的传感器的血氧计系统可用于计算脉搏和/或区域血氧饱和度。 可以从发光体发射多个光信号。 可以在第一光检测器处接收第一光信号，并且可以在第二光检测器处接收第二光信号。 可以基于接收的第一和/或第二光信号计算脉搏和/或区域血氧饱和度值。 可以基本上同时计算脉搏和区域血氧饱和度值。 计算出的脉冲和区域血氧饱和度值以及其他血氧饱和度值可以同时显示在显示器的预配置部分中。

    COMBINED PHYSIOLOGICAL SENSOR SYSTEMS AND METHODS
    6.
    发明申请
    COMBINED PHYSIOLOGICAL SENSOR SYSTEMS AND METHODS 有权
    组合生理传感器系统和方法

    公开(公告)号：US20110190600A1

    公开(公告)日：2011-08-04

    申请号：US13020704

    申请日：2011-02-03

    申请人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison

    发明人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison

    IPC分类号： A61B5/00

    CPC分类号： A61B5/02055 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02433 ,  A61B5/14552 ,  A61B5/165 ,  A61B5/6814 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/726

    摘要： A combined physiological sensor and methods for detecting one or more physiological characteristics of a subject are provided. The combined sensor (e.g., a forehead sensor) may be used to detect and/or calculate at least one of a pulse blood oxygen saturation level, a regional blood oxygen saturation level, a respiration rate, blood pressure, an electrical physiological signal (EPS), a pulse transit time (PTT), body temperature associated with the subject, a depth of consciousness (DOC) measurement, any other suitable physiological parameter, and any suitable combination thereof. The combined sensor may include a variety of individual sensors, such as electrodes, optical detectors, optical emitters, temperature sensors, and/or other suitable sensors. The sensors may be advantageously positioned in accordance with a number of different geometries. The combined sensor may also be coupled to a monitoring device, which may receive and/or process one or more output signals from the individual sensors to display information about the medical condition of the subject. In addition, several techniques may be employed to prevent or limit interference between the individual sensors and their associated input and/or output signals.

    摘要翻译： 提供组合的生理传感器和用于检测受试者的一种或多种生理特征的方法。 组合的传感器（例如，前额传感器）可用于检测和/或计算脉搏血氧饱和度水平，区域血氧饱和度水平，呼吸速率，血压，电生理信号（EPS ），脉搏传播时间（PTT），与受试者相关的体温，意识深度（DOC）测量，任何其它合适的生理参数及其任何合适的组合。 组合的传感器可以包括各种单独的传感器，例如电极，光学检测器，光发射器，温度传感器和/或其它合适的传感器。 可以根据多个不同的几何形状有利地定位传感器。 组合的传感器还可以耦合到监视设备，监视设备可以接收和/或处理来自各个传感器的一个或多个输出信号以显示关于对象的医疗状况的信息。 此外，可以采用几种技术来防止或限制各个传感器及其相关的输入和/或输出信号之间的干扰。

    SYSTEMS AND METHODS FOR COMBINED PHYSIOLOGICAL SENSORS
    7.
    发明申请
    SYSTEMS AND METHODS FOR COMBINED PHYSIOLOGICAL SENSORS 审中-公开
    用于组合生理传感器的系统和方法

    公开(公告)号：US20110112382A1

    公开(公告)日：2011-05-12

    申请号：US12944950

    申请日：2010-11-12

    申请人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    发明人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0478 ,  A61B5/02427 ,  A61B5/14551 ,  A61B2562/182

    摘要： Systems and methods are provided for monitoring the physiological state of a subject. One or more physiological parameters of a subject may be determined from a photoplethysmograph (PPG) signal or signals obtained using at least one PPG sensor. In some embodiments, an electrical physiological signal (EPS) sensor may be located in or near a PPG sensor. A sensor configuration including both PPG sensors and EPS sensors may be advantageously used to detect a PPG signal or signals in combination with one or more EPS signal or signals. To reduce potential interference between an EPS sensor and a PPG sensor, fiber-optic input and output lines may be used to transmit optical signals from light generating circuitry and light detecting circuitry. In some embodiments, the generating and detecting circuitry may be located remotely from one another and may further be located remotely from the EPS sensor, PPG sensor, or both.

    摘要翻译： 提供了用于监测受试者的生理状态的系统和方法。 受试者的一个或多个生理参数可以从光电容积描记器（PPG）信号或使用至少一个PPG传感器获得的信号来确定。 在一些实施例中，电生理信号（EPS）传感器可以位于PPG传感器中或附近。 包括PPG传感器和EPS传感器的传感器配置可以有利地用于检测与一个或多个EPS信号或信号相结合的PPG信号或信号。 为了减少EPS传感器和PPG传感器之间的潜在干扰，光纤输入和输出线路可用于从光生成电路和光检测电路传输光信号。 在一些实施例中，生成和检测电路可以彼此远离地定位，并且可以进一步远离EPS传感器，PPG传感器或两者。

    SYSTEMS AND METHODS FOR MONITORING DEPTH OF CONSCIOUSNESS
    8.
    发明申请
    SYSTEMS AND METHODS FOR MONITORING DEPTH OF CONSCIOUSNESS 有权
    监测深度深度的系统和方法

    公开(公告)号：US20120203087A1

    公开(公告)日：2012-08-09

    申请号：US13364766

    申请日：2012-02-02

    申请人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison ,  James N. Watson

    发明人： Edward M. McKenna ,  Bo Chen ,  Youzhi Li ,  Paul Stanley Addison ,  James N. Watson

    IPC分类号： A61B5/00 ,  A61B6/00 ,  A61B5/04 ,  A61B5/1455 ,  A61B5/021

    CPC分类号： A61B5/14551 ,  A61B5/04001 ,  A61B5/0476 ,  A61B5/40 ,  A61B5/4821 ,  A61B5/7239 ,  A61B5/7264 ,  G06F19/00 ,  G16H50/20 ,  G16H50/30

    摘要： During patient monitoring, a depth of consciousness (DOC) measure, such as a bispectral index, may be used in conjunction with additional information obtained from an awareness metric derived from one or more physiological signals, such as a photoplethysmograph signal. In an embodiment, a DOC measure may be combined with information from an awareness metric to produce a combined DOC measure. In an embodiment, information from an awareness metric derived from one or more physiological signals may be used to provide an indication of confidence in a DOC measure. In an embodiment, a DOC measure may be used to provide an indication of confidence in a depth of consciousness assessment based on an awareness metric. In an embodiment, one or the other of a DOC measure and an awareness metric may be used to provide an indication of a patient's depth of consciousness (e.g., by one “overriding” the other).

    摘要翻译： 在患者监视期间，可以结合从源自一个或多个生理信号（诸如光电体积描记信号）的意识度量获得的附加信息结合使用意识深度（DOC）测量，例如双谱指数。 在一个实施例中，DOC测量可以与来自感知度量的信息组合以产生组合的DOC测量。 在一个实施例中，可以使用来自一个或多个生理信号的意识度量的信息来提供在DOC测量中的置信度。 在一个实施例中，DOC测量可以用于基于意识度量提供意识深度评估深度的置信度。 在一个实施例中，可以使用DOC测量和意识度量中的一个或另一个来提供患者的意识深度的指示（例如，通过一个“覆盖”另一个）。

    SIMULTANEOUS MEASUREMENT OF PULSE AND REGIONAL BLOOD OXYGEN SATURATION
    9.
    发明申请
    SIMULTANEOUS MEASUREMENT OF PULSE AND REGIONAL BLOOD OXYGEN SATURATION 有权
    脉搏和区域血氧饱和度的同时测量

    公开(公告)号：US20110112387A1

    公开(公告)日：2011-05-12

    申请号：US12944945

    申请日：2010-11-12

    申请人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    发明人： Youzhi Li ,  Bo Chen ,  Edward M. McKenna ,  Paul Stanley Addison

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14551 ,  A61B5/7203 ,  A61B5/726

    摘要： Methods and systems are provided that allow for the simultaneous calculation of pulse and regional blood oxygen saturation. An oximeter system that includes a sensor with a plurality of emitters and detectors may be used to calculate a pulse and/or regional blood oxygen saturation. A plurality of light signals may be emitted from light emitters. A first light signal may be received at a first light detector and a second light signal may be received at a second light detector. A pulse and/or regional blood oxygen saturation value may be calculated based on the received first and/or second light signals. The pulse and regional blood oxygen saturation values may be calculated substantially simultaneously. The calculated pulse and regional blood oxygen saturation values as well as other blood oxygen saturation values may be displayed simultaneously in a preconfigured portion of a display.

    摘要翻译： 提供了允许同时计算脉搏和局部血氧饱和度的方法和系统。 包括具有多个发射器和检测器的传感器的血氧计系统可用于计算脉搏和/或区域血氧饱和度。 可以从发光体发射多个光信号。 可以在第一光检测器处接收第一光信号，并且可以在第二光检测器处接收第二光信号。 可以基于接收的第一和/或第二光信号计算脉搏和/或区域血氧饱和度值。 可以基本上同时计算脉搏和区域血氧饱和度值。 计算出的脉冲和区域血氧饱和度值以及其他血氧饱和度值可以同时显示在显示器的预配置部分中。

    Signal processing systems and methods for analyzing multiparameter spaces to determine physiological states
    10.
    发明授权
    Signal processing systems and methods for analyzing multiparameter spaces to determine physiological states 有权
    用于分析多参数空间以确定生理状态的信号处理系统和方法

    公开(公告)号：US08660625B2

    公开(公告)日：2014-02-25

    申请号：US12242915

    申请日：2008-10-01

    申请人： Paul Stanley Addison ,  James Nicholas Watson ,  Edward M. McKenna

    发明人： Paul Stanley Addison ,  James Nicholas Watson ,  Edward M. McKenna

    IPC分类号： A61B5/026 ,  A61B5/0452

    CPC分类号： G06K9/00536 ,  A61B5/14551 ,  A61B5/7207 ,  A61B5/726 ,  G06K9/00516 ,  G16H50/20

    摘要： The present disclosure relates to signal processing systems and methods, and more particularly, to systems and methods for analyzing multiparameter spaces to determine changes in a physiological state. In embodiments, a first signal and a second signal may be obtained, from which a first plurality of values of a physiological parameter may be determined. At least one of the signals also may be used to generate a scalogram derived at least in part from the signal. A second plurality of values may be determined based at least in part on a feature in the scalogram. The first and second plurality of values may then be associated, and a physiological state may be analyzed using the associated first and second values. In an embodiment, the signals may be PPG signals and the associated first and second values may include a parameter scatter plot that may permit a user to determine changes in a patient's ventilation state over time.

    摘要翻译： 本公开涉及信号处理系统和方法，更具体地，涉及用于分析多参数空间以确定生理状态的变化的系统和方法。 在实施例中，可以获得可以确定生理参数的第一多个值的第一信号和第二信号。 信号中的至少一个也可用于产生至少部分地从该信号导出的标尺图。 可以至少部分地基于缩放图中的特征来确定第二多个值。 然后可以将第一和第二多个值相关联，并且可以使用相关联的第一和第二值分析生理状态。 在一个实施例中，信号可以是PPG信号，并且相关联的第一和第二值可以包括参数散点图，其可以允许用户随时间确定患者通气状态的变化。