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公开(公告)号:US20200054842A1
公开(公告)日:2020-02-20
申请号:US16610365
申请日:2018-05-03
申请人: ARES TRADING S.A.
摘要: A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.
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公开(公告)号:US20240077481A1
公开(公告)日:2024-03-07
申请号:US18280340
申请日:2022-03-03
申请人: ARES TRADING S.A.
IPC分类号: G01N33/569 , G01N33/564
CPC分类号: G01N33/56972 , G01N33/564 , G01N2800/285 , G01N2800/52 , G01N2800/54
摘要: The invention pertains to improved treatment methods using DMDS, in particular cladribine, for the treatment of autoimmune diseases, in particular multiple sclerosis, and biomarkers, in particular immune cell subtypes, for predicting and/or optimising said treatment methods. The methods described rely on the use of immune cell subtypes, in particular T cells, B cells, NK cells subtypes and their ratios as present in blood samples from the patients for predicting and/or optimising the use of cladribine in the treatment of multiple sclerosis.
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公开(公告)号:US20230406881A1
公开(公告)日:2023-12-21
申请号:US18037787
申请日:2020-11-20
申请人: ARES TRADING S.A.
CPC分类号: C07K1/18 , C07K1/22 , B01D15/203 , B01D15/424 , B01D15/168
摘要: The invention relates to the field of protein purification processes involving several chromatography steps. The invention pertains to a method for purifying a protein, preferably an antibody or fragment thereof or a protein containing said fragment, from a complex solution, wherein said method comprises at least two chromatography steps which are performed using buffers comprising or consisting of the same chemical compounds. The invention is particularly useful for large scale production and purification of recombinant proteins.
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公开(公告)号:US20230024124A1
公开(公告)日:2023-01-26
申请号:US17782201
申请日:2019-12-20
申请人: Ares Trading S.A.
发明人: Maxime ETTORI , Craig NELSON , Michael NOBLE , John SOMERVILLE
IPC分类号: A61M37/00
摘要: Transdermal drug delivery devices are described herein such as a microneedle array patch, to be placed on the skin for transdermal delivery of a medicament. The transdermal drug delivery device for delivery of a bioactive agent through mammalian skin comprises an array of microneedles and a means to actuate the microneedles, wherein the actuation means actuates the microneedles separately.
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公开(公告)号:US20220077888A1
公开(公告)日:2022-03-10
申请号:US17415906
申请日:2018-12-19
申请人: Ares Trading S.A.
发明人: Alessandro Macor , Wim Saelen , Charles Henderson , Peter Relph
IPC分类号: H04B1/707 , H04B5/00 , G06K7/00 , G06K19/077 , G06K19/07
摘要: There is described a communication system (1) comprising a central unit (3) and a communication element (20). The central unit (3) comprises at least one RF antenna (4), a transmitter (6) configured to transmit a RF signal and a receiver (8) configured to receive a backscattered RF signal. The communication element (20) comprises a RF antenna (22) and a modulator (23) configured to backscatter the RF signal. The communication element (20) comprises a means for modulating the backscattered RF signal into a spread spectrum backscattered RF signal, and a means for supplying power.
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公开(公告)号:US10583118B2
公开(公告)日:2020-03-10
申请号:US16020304
申请日:2018-06-27
申请人: Ares Trading S.A.
发明人: Nicoletta Maxia
IPC分类号: A61K31/4045 , A61K9/00 , A61K31/165 , C12N5/071 , A61B17/435 , A61B17/42
摘要: The present invention refers to the use of N-acetyl-5-methoxytryptamine (melatonin) and/or an analogue thereof, for use in the medical or veterinary field in the assisted reproduction for promoting the mechanism of implantation of the embryo, and in particular for the prevention of implantation failure into the uterus, by topical administration of an effective amount in a mammalian subject female in need of such treatment, and related compositions, culture media and medical devices.
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公开(公告)号:US20180303798A1
公开(公告)日:2018-10-25
申请号:US16020304
申请日:2018-06-27
申请人: Ares Trading S.A.
发明人: Nicoletta Maxia
IPC分类号: A61K31/4045 , A61K9/00 , C12N5/071 , A61K31/165 , A61B17/435 , A61B17/42
CPC分类号: A61K31/4045 , A61B17/435 , A61B2017/4216 , A61K9/0034 , A61K9/0039 , A61K31/165 , C12N5/0682 , C12N2501/825
摘要: The present invention refers to the use of N-acetyl-5-methoxytryptamine (melatonin) and/or an analogue thereof, for use in the medical or veterinary field in the assisted reproduction for promoting the mechanism of implantation of the embryo, and in particular for the prevention of implantation failure into the uterus, by topical administration of an effective amount in a mammalian subject female in need of such treatment, and related compositions, culture media and medical devices.
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公开(公告)号:US09527853B2
公开(公告)日:2016-12-27
申请号:US14406386
申请日:2013-06-14
申请人: Ares Trading S.A.
发明人: Ben Whittaker , Chris Steele , David Hardick , Dale Mitchell , Vincent Pomel , Anna Quattropani , Dirk Beher
IPC分类号: C07D401/00 , C07D419/00 , C07D487/00 , C07D249/16 , C07D403/00 , A61K31/535 , A61K31/41 , A61K31/415 , C07D487/04 , C07D471/04 , C07D498/04 , A61K31/4192 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/5383 , A61K45/06
CPC分类号: C07D487/04 , A61K31/4192 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/5383 , A61K45/06 , C07D471/04 , C07D498/04
摘要: The present invention provides fused bicyclic triazole derivatives of Formula (I) useful as gamma secretase modulators (GSM), for the treatment of Alzheimer's disease and related diseases.
摘要翻译: 本发明提供用作γ-分泌酶调节剂(GSM)的用于治疗阿尔茨海默病和相关疾病的式(I)的稠合双环三唑衍生物。
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公开(公告)号:US20160317668A1
公开(公告)日:2016-11-03
申请号:US15105622
申请日:2014-12-23
申请人: ARES TRADING S.A.
CPC分类号: A61K47/36 , A61K9/0019 , A61K9/0024 , A61K38/1825 , A61K47/02 , A61L27/52 , A61L27/54 , A61L2300/414 , A61L2430/06
摘要: The invention relates to the field of pharmaceutical formulations. More particularly it is directed to xyloglucan hydrogels comprising Fibroblast Growth Factor 18 (FGF-18) compound and to methods of producing such hydrogels. The hydrogels of the invention can be used, once formed in situ, for the treatment of cartilage disorders such as osteoarthritis or cartilage injury.
摘要翻译: 本发明涉及药物制剂领域。 更具体地,涉及包含成纤维细胞生长因子18(FGF-18)化合物的木葡聚糖水凝胶以及制备这种水凝胶的方法。 本发明的水凝胶一旦在原位形成,可以用于治疗软骨疾病如骨关节炎或软骨损伤。
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公开(公告)号:US20160246943A1
公开(公告)日:2016-08-25
申请号:US15031770
申请日:2014-10-25
申请人: ARES TRADING S.A.
发明人: COLIN LAKE , ANDREW PATERSON , SIMON EXELL , ERIC CHANIE , GEORGIOS KOUVAS
IPC分类号: G06F19/00
摘要: Patient care system comprising a medical device (1) for administering a medical treatment to a patient (15a) and a server system (6) configured to receive and transmit data via a communications network (16) to, respectively from users including patients (15a) and health care professionals (15b), the server system further configured to process and store data related to patient care. The server system comprises a database (6c) configured to encrypt and store encrypted data related to patient care, an application server (6b) including patient care software components for disease management (36) and patient information management (32), a communication server (6a) including a web server software application for data transfer through the internet, the patient care software components operable to receive medical device usage data comprising data on the usage of said medical device transferred through the communications network, and further operable to process said medical device usage data in conjunction with patient data (32c) to generate a report (32f) or a plurality of reports related to the treatment of the patient, the reports being accessible remotely via the communications network by registered users of the patient care system as a function of respective roles and privileges of the registered user stored in the server system.
摘要翻译: 包括用于向患者(15a)施用医疗的医疗装置(1)和被配置为经由通信网络(16)将数据经由通信网络(16)接收并发送到包括患者(15a)的用户的服务器系统 )和保健专业人员(15b),服务器系统进一步配置为处理和存储与患者护理有关的数据。 服务器系统包括被配置为加密和存储与患者护理有关的加密数据的数据库(6c),包括用于疾病管理(36)和患者信息管理(32)的患者护理软件组件的应用服务器(6b),通信服务器 6a)包括用于通过因特网进行数据传输的web服务器软件应用程序,所述病人护理软件组件可操作以接收包括关于通过通信网络传送的所述医疗设备的使用的数据的医疗设备使用数据,并且还可操作以处理所述医疗设备 使用数据结合患者数据(32c)以生成报告(32f)或与患者治疗相关的多个报告,所述报告可以通过病人护理系统的注册用户经由通信网络远程访问作为功能 存储在服务器系统中的注册用户的各自角色和特权。
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