公开(公告)号：US20240130948A1

公开(公告)日：2024-04-25

申请号：US18022244

申请日：2021-08-19

申请人： ISP INVESTMENTS LLC

发明人： Feng LING ,  NING Ling ,  BU Tianyun

IPC分类号： A61K8/65 ,  A61Q19/02 ,  A61Q19/08

CPC分类号： A61K8/65 ,  A61Q19/02 ,  A61Q19/08 ,  A61K2800/592

摘要： The present invention relates to compositions and methods for improving the appearance of the skin. Compositions comprises at least water, glycerin, sodium PCA, erythritol, Carrageenan (Chondrus Crispus extract), xanthan Gum; hydrolyzed collagen, hexapeptide-9 and a physiologically acceptable medium. Methods comprise applying the compositions to the skin to improve the appearance of aging skin, increasing skin moisturization, refining skin pores and decreasing aging skin pigmentation defects.

公开(公告)号：US20240059806A1

公开(公告)日：2024-02-22

申请号：US18259972

申请日：2022-01-06

申请人： ISP Investments LLC

发明人： OSAMA M. MUSA ,  Rebecca Roisin GIBSON ,  Steven Peter ARMES

IPC分类号： C08F8/00

CPC分类号： C08F8/00 ,  C08F2438/03

摘要： The invention provides a process for removal of a thio-based end group from a polymer comprising repeating units derived from at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by subjecting the polymer to radiation in a reaction medium devoid of any chemical reagent. Exemplary process involves removal of thio-based end groups from polymers prepared by reversible addition-fragmentation chain transfer polymerization of at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by exposing the polymer to visible radiation in a reaction medium devoid of any chemical reagent.

公开(公告)号：US11766397B2

公开(公告)日：2023-09-26

申请号：US16706677

申请日：2019-12-07

申请人： ISP INVESTMENTS LLC

发明人： Michael Koganov

IPC分类号： A61K8/9789 ,  A61Q19/02

CPC分类号： A61K8/9789 ,  A61Q19/02

摘要： The present invention provides bioactive compositions comprising Ficus serum fraction derived from Ficus cell juice of fresh Ficus leaves and a process of preparing the Ficus serum fraction. The compositions have biological activity capable of reducing skin hyperpigmentation.

公开(公告)号：US20230263712A1

公开(公告)日：2023-08-24

申请号：US18012373

申请日：2021-06-28

申请人： ISP INVESTMENTS LLC

发明人： Hani M. FARES ,  Yevgeniy TUROVSKIY ,  Solomon Howard JACOBSON ,  Philip John OTHS ,  Petros GEBRESELASSIE ,  Joseph TORELLA ,  Karen WINKOWSKI

IPC分类号： A61K8/35 ,  A61Q11/00

CPC分类号： A61K8/35 ,  A61Q11/00 ,  A61K2800/524 ,  A61K2800/92 ,  A61K2800/74

摘要： An oral care antimicrobial composition comprises about 0.1 to about 99.9 wt. % of at least one compound having the structure of




Also disclosed is a process for preparing the composition and methods of use thereof.

公开(公告)号：US20230240953A1

公开(公告)日：2023-08-03

申请号：US18011903

申请日：2021-06-28

申请人： ISP INVESTMENTS LLC

发明人： Solomon Howard JACOBSON ,  Yevgenly TUROVSKIY ,  Joseph TORELLA ,  Karen WINKOWSKI

IPC分类号： A61K8/35

CPC分类号： A61K8/35 ,  A61K2800/74 ,  A61K2800/524

摘要： The present application provides an antimicrobial composition comprising: (a) about 0.01 to about 99.9 wt. % of at least one compound having a structure of formula (I) or formula (II):




wherein R1 is hydrogen, alkyl, alkoxy or hydroxyl; R2 is hydrogen, alkyl or alkoxy; and (b) about 0.1 to about 95% wt. % of one or more antimicrobial compounds not being compounds of formula (I) and formula (II). Also disclosed is a process for preparing the compositions and method of use thereof.

公开(公告)号：US20230015456A1

公开(公告)日：2023-01-19

申请号：US17939193

申请日：2022-09-07

申请人： ISP INVESTMENTS LLC

发明人： Corinne COQUET

IPC分类号： A61K8/92 ,  A61K8/9789 ,  A61K8/37 ,  A61K8/66 ,  A61Q19/08 ,  C11B15/00 ,  A61K8/97

摘要： The invention relates to a method for obtaining the water-insoluble fraction of Carica papaya sap, enriched with Carica papaya lipase, the water-insoluble fraction obtainable by this method, a method for the preparation of an activated fat and/or an activated wax by means of said water-insoluble fraction of the Carica papaya sap, the activated fat and/or the activated wax capable of being obtained by this method, a composition combining said activated fat and/or said activated wax, as well as the cosmetic use of these products.

公开(公告)号：US20220387290A1

公开(公告)日：2022-12-08

申请号：US17613841

申请日：2020-02-18

申请人： ISP INVESTMENTS LLC

发明人： Donald I PRETTYPAUL ,  Diane M. KENNEDY ,  Hani M. FARES

IPC分类号： A61K8/81 ,  A61K8/06 ,  A61K8/35 ,  A61K8/365 ,  A61K8/40 ,  A61Q17/04

摘要： Disclosed herein is a sunscreen composition(s) comprising (i) at least one sunscreen active ingredient(s); (ii) at least one copolymer of vinyl pyrrolidone (VP) and styrene; and (iii) at least one pharmaceutically or cosmetically or dermatologically acceptable excipient. Also disclosed is a method of protecting human skin and animal skin against damages caused by ultra-violet (UV) radiations from the sun rays.

公开(公告)号：US20220030862A1

公开(公告)日：2022-02-03

申请号：US17297628

申请日：2019-12-02

申请人： ISP INVESTMENTS LLC

发明人： Meiyan GUO ,  Karen WINKOWSKI ,  Najeeb H. HAKIMI ,  Raman PREMACHANDRAN ,  Xin QU

IPC分类号： A01N43/28 ,  A01N31/14 ,  A01N37/28 ,  A01N31/02

摘要： Described herein is a synergistic preservative composition used for providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds selected from the group consisting of propanediol, capryl hydroxamic acid, and isopropyl methyl phenol; and (iii) about 0.1 wt. % to 99.0 wt. % of phenoxyethanol, a preservative compound, and wherein, the composition provides synergy having Synergy Index (SI) value of the total composition from about 0.05 to about 1.0. Also described is a process for preparing said synergistic preservative composition and method of using the same.

公开(公告)号：US11224222B2

公开(公告)日：2022-01-18

申请号：US15561222

申请日：2016-03-25

申请人： ISP Investments LLC

发明人： Raman Premachandran ,  Kalpa Metha ,  Jyoti Gupta ,  Najeeb H. Hakimi ,  Karen W Winkowski

IPC分类号： A61K8/35 ,  A01N43/16 ,  A61Q19/00 ,  A61K8/49 ,  A01N25/02 ,  A61Q5/02

摘要： What is described herein is a stable and reduced-yellowing/non-yellowing synergistic preservative composition comprising: (i) about 0.1 wt. % to about 40 wt. % of dehydroacetic acid (DHA); and about 0.1 wt. % to about 99.9 wt. % of at least one aprotic solvent. Also described herein are aqueous and non-aqueous based preservative compositions for various end-user applications, and processes for preparing and using such compositions to reduce yellowing of DHA when added to the end-user applications.

公开(公告)号：US20210347978A1

公开(公告)日：2021-11-11

申请号：US17277686

申请日：2019-09-17

申请人： ISP INVESTMENTS LLC

发明人： Thomas DURIG ,  Paul C. GILLETTE ,  Michael A. TALLON

IPC分类号： C08L39/06 ,  C08L31/04 ,  A61K45/06 ,  A61K47/32 ,  A61K47/10

摘要： A peroxide stable polymer composition comprises a mixture of polyvinylpyrrolidone/vinyl acetate copolymer (PVP/VA) and butylated hydroxy anisole (BHA), an antioxidant. Products or applications comprising said stable polymer composition and a process for the preparation thereof are disclosed in the present application.