公开(公告)号：US20240385089A1

公开(公告)日：2024-11-21

申请号：US18789567

申请日：2024-07-30

Applicant: INNOVAPREP LLC

Inventor： Alec D. Adolphson ,  Andrew E. Page ,  John D. Birkenholz ,  David Goad

IPC: G01N1/34 ,  B01L3/00

Abstract: Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening.

公开(公告)号：US12013322B2

公开(公告)日：2024-06-18

申请号：US17194169

申请日：2021-03-05

Applicant: INNOVAPREP LLC

Inventor： Andew Edward Page ,  Zachary A. Packingham ,  David Scott Alburty ,  Alec D. Adolphson

IPC: G01N1/40 ,  B01L3/02 ,  C12Q1/24

CPC classification number: G01N1/4077 ,  B01L3/0275 ,  C12Q1/24 ,  B01L2200/026 ,  B01L2200/0631 ,  B01L2300/0681 ,  B01L2300/161 ,  G01N2001/4088

Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.

公开(公告)号：US20240139724A1

公开(公告)日：2024-05-02

申请号：US18384345

申请日：2023-10-26

Applicant: INNOVAPREP LLC

Inventor： Andrew E. Page ,  David Goad ,  Steven D. Graham

IPC: B01L3/02 ,  A61M5/315 ,  G01N35/10

CPC classification number: B01L3/0217 ,  A61M5/31565 ,  B01L3/0275 ,  G01N35/1004 ,  B01L2300/0681 ,  B01L2400/0487 ,  B01L2400/0622 ,  B01L2400/0644 ,  G01N2035/1006

Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with a rotary distribution valve connected to a syringe pump which maintains control and flow of various fluids to a sample through a retentate port.

公开(公告)号：US20210208032A1

公开(公告)日：2021-07-08

申请号：US17209434

申请日：2021-03-23

Applicant: InnovaPrep LLC

Inventor： Andrew Edward Page ,  Zachary A. Packingham ,  David Scott Alburty ,  Alec D. Adolphson

IPC: G01N1/10 ,  G01N1/34 ,  G01N1/40 ,  G01N1/14

Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

公开(公告)号：US10718696B2

公开(公告)日：2020-07-21

申请号：US15397524

申请日：2017-01-03

Applicant: InnovaPrep LLC

Inventor： Andrew Edward Page ,  David Scott Alburty ,  Alec D. Adolphson ,  Pamela S. Murowchick ,  Zachary A. Packingham

IPC: G01N1/40 ,  G01N1/22 ,  B01D46/00 ,  B01D46/54

Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.

公开(公告)号：US11839837B2

公开(公告)日：2023-12-12

申请号：US17209420

申请日：2021-03-23

Applicant: InnovaPrep LLC

Inventor： David Scott Alburty ,  Michael Lee Hornback ,  Bryan Charles Long ,  Andrew Edward Page

IPC: A47G19/22 ,  B01D19/00 ,  G01N1/40 ,  G01N1/42 ,  C12H1/18 ,  A23L5/20 ,  G01N33/14

CPC classification number: B01D19/0073 ,  A23L5/21 ,  A47G19/22 ,  A47G19/2233 ,  B01D19/00 ,  C12H1/18 ,  G01N1/4005 ,  G01N1/4055 ,  G01N1/42 ,  G01N33/146 ,  A23V2002/00

Abstract: Devices, systems and methods are disclosed which relate to using containers with a multitude of nucleation sites covering a major portion of the inside wall of the container to enable rapid and nearly complete removal of soluble gases from fluid samples, including carbonated beverages and other carbonated fluid samples. A fluid sample is rapidly poured into the described container initiating a catastrophic release of the soluble gas from the sample.

公开(公告)号：US20230358153A1

公开(公告)日：2023-11-09

申请号：US18135104

申请日：2023-04-14

Applicant: INNOVAPREP LLC

Inventor： Steven D. Graham ,  Alec Adolphson ,  Bryan Long

IPC: F01N1/08 ,  F01N1/10 ,  F01N13/00

CPC classification number: F01N1/083 ,  F01N1/10 ,  F01N13/002

Abstract: Devices, systems and methods are described for reducing noise emitted from active aerosol and bioaerosol collection devices. The system includes a noise reducing muffler between the collection component and the air mover and a noise reducing baffle at the outlet of the air mover. The muffler reduces higher frequency noises emitted from the air mover inlet while the baffle reduces lower frequency noises emitted from the air mover outlet. Placement of the muffler between the collection component and the air mover eliminates the potential for loss of particles to the muffler prior to collection.

公开(公告)号：US20230146816A1

公开(公告)日：2023-05-11

申请号：US17984204

申请日：2022-11-09

Applicant: INNOVAPREP LLC

Inventor： Michael Fischer ,  Bryan Long ,  Steven D. Graham ,  Sidney J. Spry ,  Alec Adolphson ,  John D. Birkenholz ,  Andrew E. Page ,  David S. Alburty

IPC: B01L3/00

CPC classification number: B01L3/505

Abstract: Devices, systems, and methods are disclosed which relate to using a use large area surface sampler with invertible bag for collection of biological and non-biological particles prior to subsequent analysis. The large area surface sampler with invertible bag uses an inverted bag with bonded sampling material to first serve as a sampling device followed by the bag being turned right side out and the captured particles being extracted inside of the bag. The device includes measures for sealing liquid in the sampling material using a protective cup at time of manufacture. This enables users to simply remove the protective cup and perform wet surface sampling prior to turning the bag right side out and removing captured particles from the sampling material with repeated compressions. The described device, systems and methods allow users to capture and elute surface samples for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required.

公开(公告)号：US08677839B2

公开(公告)日：2014-03-25

申请号：US12814972

申请日：2010-06-14

Applicant: Andrew Edward Page ,  David Scott Alburty ,  Zachary A. Packingham ,  Pamela S. Murowchick ,  Alec D. Adolphson

Inventor： Andrew Edward Page ,  David Scott Alburty ,  Zachary A. Packingham ,  Pamela S. Murowchick ,  Alec D. Adolphson

IPC: G01N1/00

CPC classification number: G01N1/02 ,  G01N2001/028 ,  G01N2001/1445

Abstract: Novel rapid, efficient sample collection systems, devices and methods are disclosed which remove and capture particles, and especially biological particles from surfaces into a liquid sample. The devices were developed primarily for obtaining samples of biological contamination from environmental surfaces. Biological particles, as described here, include bacteria, viruses, and other microorganisms, and other particles of biological origin including nucleic acids, proteins, and toxins.

Abstract translation: 公开了新颖的快速，有效的样品收集系统，装置和方法，其将颗粒，特别是生物颗粒从表面去除和捕获到液体样品中。 这些装置主要用于从环境表面获得生物污染的样品。 如本文所述的生物颗粒包括细菌，病毒和其它微生物以及生物来源的其它颗粒，包括核酸，蛋白质和毒素。

公开(公告)号：US20140076071A1

公开(公告)日：2014-03-20

申请号：US14084403

申请日：2013-11-19

Applicant: INNOVAPREP LLC

Inventor： Andrew Edward Page ,  David Scott Alburty ,  Alec D. Adolphson ,  Pamela S. Murowchick ,  Zachary A. Packingham

IPC: G01N1/22

CPC classification number: G01N1/4077 ,  B01D46/0032 ,  B01D46/0067 ,  B01D46/543 ,  G01N1/2205 ,  G01N1/2273 ,  G01N2001/4088

Abstract: Devices, systems and methods are disclosed which relate to using a wet foam elution method for removal of particles from a flat filter. Particles are captured from the atmosphere onto the flat filter. The flat filter is then placed into an extractor which passes a stream of wet foam through the flat filter. Expansion of the foam works to efficiently remove captured particles. The foam flows from the filter along with the captured particles into a sample container. Once in the sample container, the foam quickly breaks down leaving an analysis ready liquid sample.

Abstract translation: 公开了涉及使用湿泡沫洗脱法从扁平过滤器去除颗粒的装置，系统和方法。 颗粒从大气中捕获到扁平过滤器上。 然后将扁平过滤器放入提取器中，该提取器将湿泡沫流通过扁平过滤器。 泡沫的膨胀用于有效去除捕获的颗粒。 泡沫从捕获的颗粒与过滤器一起流入样品容器。 一旦在样品容器中，泡沫快速分解，留下分析就绪的液体样品。