Abstract:
The present invention provides a method of producing polymer particles by precipitation polymerisation, the method comprising: providing a reaction solution comprising (i) solvent, (ii) a photo-active compound that upon being subjected to a wavelength of light forms two o-quinodimethane structures, and (iii) a multi-dienophile compound; subjecting the reaction solution to the wavelength of light, which promotes step-growth Diels-Alder polymerisation of the photo-active and multi-dienophile compounds; wherein as a result of the step-growth Diels-Alder polymerisation polymer precipitates from the reaction solution and self-assembles into the polymer particles.
Abstract:
A lighting device providing emitted light with an adjustable correlated color temperature (CCT) is described. The lighting device comprises one or more light emitters and a controller configured to independently control each of the one or more light emitters. Each respective light emitter is configured to provide one or more spectral components of the emitted light, wherein the emitted light comprises a respective photoreceptor-to-photopic luminance activation ratio for each ocular photoreceptor class corresponding to an intended CCT of the emitted light. The respective photoreceptor-to-photopic luminance activation ratios comprise each of (a) a melanopsin (i)-to-photopic-luminance activation ratio; (b) a rhodopsin (R)-to-photopic-luminance activation ratio; (c) a long-wavelength sensitive opsin (L)-to-photopic-luminance activation ratio; (d) a middle-wavelength sensitive opsin (M)-to-photopic-luminance activation ratio; and (e) a short-wavelength sensitive opsin (S)-to-photopic-luminance activation ratio. Each of (a); (b); (c); (d); and (e) are within a defined range of a respective activation ratio of a blackbody radiator with the intended CCT. The emitted light may have variable excitation ratios for the five photoreceptors prompting a biological response matching that of a different blackbody radiator with changes that are invisible to the eye or difficult to perceive.
Abstract:
Provided herein is a method of at least partly removing a biological deposit, such as a dag, from the skin of an animal. The method includes administering to the biological deposit an effective amount of a composition containing a keratinase, and optionally one or both of a reducing agent and a surfactant. Also provided is a composition for use in the aforementioned method as well as a method of making same.
Abstract:
An ophthalmic imaging apparatus comprising: an illumination light source and an optical assembly for directing light from the light source into an eye of a subject; a photosensor array comprising a plurality of photosensors positioned for acquiring images of portions of a fundus of the eye; an objective lens positioned along an imaging axis intersecting a point on the fundus of the eye wherein the objective lens is positioned for refracting light that has been reflected by the fundus to form an image of the fund us on an image plane of the objective lens such that the image plane is positioned away from the photosensor array; and a microlens array comprising a plurality of microlenses wherein the microlens array is spaced away from and positioned behind the image plane and wherein the microlens array is positioned in between the image plane and the photosensor array such that each microlens in the array projects a different view of the image formed at the image plane thereby forming an array of elemental images on the photosensor array.
Abstract:
A method of forming a coating on a substrate is provided comprising forming a lignin solution by at least partially dissolving lignin in a solvent, coating the lignin solution onto the substrate and exposing the lignin coated substrate to a treatment selected from the group consisting of a heat treatment and an acid treatment. The coating provides for improved waterproofing and/or strengthening of the substrate.
Abstract:
A swim training apparatus for training a user during swimming, the apparatus including, an at least semi-rigid body, an attachment mechanism to allow the body to be worn by the user so that at least part of the body contacts the user's torso to thereby provide at least one of resistance training for improving at least one of strength and stability of the user, and posture training for guiding user posture.
Abstract:
This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly FGFR2 variants, which are linked to drug resistance. The disclosure further provides methods of diagnosis and theranosis, and development of new therapeutic agents using these molecules and fragments thereof, and kits for employing these methods and compositions.
Abstract:
The present invention provides methods for producing a transformed sugar cane tissue or cell thereof, said methods comprising: a) inoculating a sugar cane tissue or a cell thereof with an Agrobacterium inoculation suspension, said Agrobacterium comprising a nucleic acid of interest, to obtain an Agrobacterium-inoculated sugar cane tissue or cell thereof; b) co-cultivating said Agrobacterium-inoculated sugar cane tissue or cell thereof on a surface in the absence of co-culture media for a time period sufficient to reduce original weight of said Agrobacterium-inoculated sugar cane tissue or cell thereof; and c) selecting a transformed sugar cane tissue or a cell thereof comprising said nucleic acid of interest. The transformation methods of the invention provide for increased transformation frequency and recovery of transgenic sugar cane plants.
Abstract:
A sugar cane plant cell comprising a recombinant nucleic acid molecule is provided, the recombinant nucleic acid molecule comprising a nucleotide sequence of interest, a promoter and the nucleotide sequence of SEQ ID NO:1, wherein the promoter is downstream of and in operative association with the nucleotide sequence of SEQ ID NO:1 and upstream of and in operative association with the nucleotide sequence of interest, and the nucleotide sequence of interest is expressed at a level at least about 6 times greater than the level of expression of said nucleotide sequence of interest in a control. Additionally, a method of increasing the expression of a nucleotide sequence of interest in a sugar cane plant cell using the recombinant nucleic acid molecule of the invention is provided.
Abstract translation:提供了包含重组核酸分子的甘蔗植物细胞,所述重组核酸分子包含目的核苷酸序列,启动子和SEQ ID NO:1的核苷酸序列,其中所述启动子位于SEQ ID NO:1的下游且与 SEQ ID NO:1的核苷酸序列并与感兴趣的核苷酸序列上游并且与目标核苷酸序列有效结合,并且感兴趣的核苷酸序列的表达水平比所述核苷酸序列的表达水平至少大约6倍 控制权益。 另外,提供了使用本发明的重组核酸分子增加甘蔗植物细胞中目的核苷酸序列的表达的方法。
Abstract:
The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce useful products, such as fermentable sugars.