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公开(公告)号：US20070197597A1
公开(公告)日：2007-08-23
申请号：US11469599
申请日：2006-09-01
IPC分类号： A61K31/452 , C07D405/02
CPC分类号： C07F7/10 , C07D211/26 , C07D211/52 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/53 , C07D405/06
摘要： This invention is directed to processes for the preparation of a compound of the formula I or salt thereof, that is useful as a tryptase inhibitor, to intermediates useful in the preparation of such a compound, to processes for the preparation of such intermediates, and to the use of such intermediates for the preparation of such a compound.
摘要翻译： 本发明涉及制备式I化合物或其盐的方法，其可用作类胰蛋白酶抑制剂，可用于制备这种化合物的中间体，制备这种中间体的方法，以及 使用这样的中间体制备这种化合物。
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公开(公告)号：US20210121577A1
公开(公告)日：2021-04-29
申请号：US17064482
申请日：2020-10-06
IPC分类号： A61K47/38 , A61K31/192 , A61K31/522 , A61K9/20
摘要： The invention relates to a film coated tablet for the treatment of acute pain containing 400 mg of ibuprofen, 100 mg of caffeine, 50 to 100 mg of one or more disintegrating agents and to a process for the preparation of the film coated tablet according to the invention.
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公开(公告)号：US20110015400A1
公开(公告)日：2011-01-20
申请号：US12895068
申请日：2010-09-30
IPC分类号： C07D405/06
CPC分类号： C07F7/10 , C07D211/26 , C07D211/52 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/53 , C07D405/06
摘要： This invention is directed to processes for the preparation of a compound of the formula I or salt thereof, that is useful as a tryptase inhibitor, to intermediates useful in the preparation of such a compound, to processes for the preparation of such intermediates, and to the use of such intermediates for the preparation of such a compound.
摘要翻译： 本发明涉及制备式I化合物或其盐的方法，其可用作类胰蛋白酶抑制剂，可用于制备这种化合物的中间体，制备这种中间体的方法，以及 使用这样的中间体制备这种化合物。
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公开(公告)号：US20240350733A1
公开(公告)日：2024-10-24
申请号：US18758133
申请日：2024-06-28
发明人： Stephan Riedel
CPC分类号： A61M5/20 , A61M5/321 , A61M5/3257 , A61M2005/2013 , A61M2005/3247 , A61M2005/3267 , A61M2205/6081
摘要： Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device.
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公开(公告)号：US12102802B2
公开(公告)日：2024-10-01
申请号：US18619408
申请日：2024-03-28
CPC分类号： A61M5/31 , A61M5/24 , A61M5/321 , A61M2005/2407 , A61M2005/2414 , A61M2005/2437 , A61M5/3202
摘要： Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
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公开(公告)号：US12083326B2
公开(公告)日：2024-09-10
申请号：US17527748
申请日：2021-11-16
发明人： Stefan Wendland , Michael Harms
CPC分类号： A61M5/3213 , A61M5/3202 , A61M5/3219 , A61M5/50 , A61M2005/312 , A61M2005/3217 , A61M2205/273
摘要： The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed.
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公开(公告)号：US12070584B2
公开(公告)日：2024-08-27
申请号：US17574449
申请日：2022-01-12
发明人： Frank Erbstein , Paul Richard Draper , Robert Frederick Veasey , David Aubrey Plumptre , Joseph Butler
CPC分类号： A61M5/3155 , A61M5/20 , A61M5/31568 , A61M5/24 , A61M2005/3126 , A61M2205/3306 , A61M2205/3317 , A61M2205/3327 , A61M2205/3561 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581
摘要： A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
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公开(公告)号：US20240238528A1
公开(公告)日：2024-07-18
申请号：US18619525
申请日：2024-03-28
CPC分类号： A61M5/31 , A61M5/24 , A61M5/321 , A61M2005/2407 , A61M2005/2414 , A61M2005/2437 , A61M5/3202
摘要： Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
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公开(公告)号：US20240238527A1
公开(公告)日：2024-07-18
申请号：US18619408
申请日：2024-03-28
CPC分类号： A61M5/31 , A61M5/24 , A61M5/321 , A61M2005/2407 , A61M2005/2414 , A61M2005/2437 , A61M5/3202
摘要： Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
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公开(公告)号：US20240238523A1
公开(公告)日：2024-07-18
申请号：US18622358
申请日：2024-03-29
CPC分类号： A61M5/2033 , A61M5/50 , A61M2005/206 , A61M2005/208 , A61M5/326
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).
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