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18 条记录 (耗时 0.018 秒)

    Isolation and confirmation of analytes from test devices
    3.
    发明授权
    Isolation and confirmation of analytes from test devices 失效
    从测试设备中分离和确认分析物

    公开(公告)号：US07241626B2

    公开(公告)日：2007-07-10

    申请号：US10712419

    申请日：2003-11-12

    申请人： Jingkun Li

    发明人： Jingkun Li

    IPC分类号： G01N33/53

    CPC分类号： G01N33/558 ,  Y10S436/807

    摘要： Methods, articles, and kits for obtaining elevated concentrations of a substance from a sample that has become bound, for example by providing a positive test result in an immunoassay or other binding assay. The concentrated substance is optionally subjected to further processing or analysis, for example to confirm the identity of the substance, such as a pathogenic organism in a food sample.

    摘要翻译： 用于从已经变得结合的样品中获得物质的浓度升高的方法，制品和试剂盒，例如通过在免疫测定或其它结合测定中提供阳性测试结果。 浓缩物质任选地进行进一步的加工或分析，例如以确认物质，例如食品样品中的致病生物体的身份。

    Cell-based assay for the detection of toxic analytes
    4.
    发明授权
    Cell-based assay for the detection of toxic analytes 有权
    用于检测毒性分析物的基于细胞的检测方法

    公开(公告)号：US07214505B1

    公开(公告)日：2007-05-08

    申请号：US09979699

    申请日：2000-05-05

    申请人： Colin Cooper ,  Edman Tsang ,  Robbie Burch ,  Jay Lewington

    发明人： Colin Cooper ,  Edman Tsang ,  Robbie Burch ,  Jay Lewington

    IPC分类号： C12Q1/02

    CPC分类号： G01N33/52 ,  C12Q1/02 ,  C12Q1/66 ,  C12Q2304/60 ,  G01N2430/10 ,  Y10S435/909

    摘要： Cell-based reagents and methods of using the reagents for detecting analytes are provided. The adsorbing of cells with signal-generating metabolic activity to solid supports has been found to improve the sensitivity of known cell based assays. Signal-generating cells adsorbed to a solid support are introduced to a test agent, and the measured decrease in metabolic signal provides a measure of the toxicity of the test agent.

    摘要翻译： 提供了基于细胞的试剂和使用试剂检测分析物的方法。 已经发现将具有产生信号的代谢活性的细胞吸附到固体支持物上可以提高已知基于细胞的测定的灵敏度。 吸附到固体支持物上的信号发生细胞被引入到测试试剂中，并且所测量的代谢信号的降低提供了测试试剂的毒性的量度。

    Bacteriophages as Selective Agents
    6.
    发明申请
    Bacteriophages as Selective Agents 有权
    噬菌体作为选择剂

    公开(公告)号：US20080213752A1

    公开(公告)日：2008-09-04

    申请号：US12034765

    申请日：2008-02-21

    申请人： James W. Stave ,  George B. Teaney

    发明人： James W. Stave ,  George B. Teaney

    IPC分类号： C12Q1/70 ,  C12N7/00

    CPC分类号： C12Q1/04 ,  C12N2795/00011 ,  C12N2795/00032

    摘要： Compositions containing bacteriophages and methods of using bacteriophages in microorganism detection assays and microbial growth and plating media are disclosed. The lytic ability of these phages to control the growth of non-target populations provides superior sensitivity and specificity to detection assays and reduces false negative and false positive results. The removal of contaminating bacteria reduces the microbial competition for nutrients in the growth media thereby increasing the efficiency and productivity of the culture. The phage treatment of the sample increases the proportion of target microorganisms in the sample over contaminating bacteria thereby requiring less time for enrichment to obtain a significant signal improving overall signal to noise ratio in assays and providing for higher yield of end product in microbiological production systems.

    摘要翻译： 公开了包含噬菌体的组合物和在微生物检测测定和微生物生长和电镀培养基中使用噬菌体的方法。 这些噬菌体控制非目标群体生长的溶解能力为检测测定提供了出色的灵敏度和特异性，并减少了假阴性和假阳性结果。 污染细菌的去除减少了生长培养基中营养物的微生物竞争，从而提高了培养物的效率和生产力。 样品的噬菌体处理增加了样品中目标微生物在污染细菌上的比例，从而需要更少的浓缩时间来获得显着的信号，从而提高了测定中的整体信噪比，并提供了微生物生产系统中最终产品的更高产量。

    Cell-Based Assay for the Detection of Toxic Analytes
    7.
    发明申请
    Cell-Based Assay for the Detection of Toxic Analytes 审中-公开
    用于检测有毒分析物的基于细胞的测定

    公开(公告)号：US20080113401A1

    公开(公告)日：2008-05-15

    申请号：US11742173

    申请日：2007-04-30

    申请人： Colin Cooper ,  Jay Lewington ,  Edman Tsang ,  Robbie Burch

    发明人： Colin Cooper ,  Jay Lewington ,  Edman Tsang ,  Robbie Burch

    IPC分类号： C12Q1/02

    CPC分类号： G01N33/52 ,  C12Q1/02 ,  C12Q1/66 ,  C12Q2304/60 ,  G01N2430/10 ,  Y10S435/909

    摘要： Assays for detecting potentially toxicdanalytes utilize a preparation of eukaryotic or prokaryotic cells which have signal-generating metabolic activity. The sensitivity of such assays is significantly improved by the employment of a particulate solid-phase adsorbent e.g. silica gel, which can be preliminarily mixed either with the suspected toxic analyte or with the cellular reagent. It is found that the presence of either the adsorbent-analyte combination or the adsorbent-cellular reagent combination results in an amplification of the decrease of the intensity of the generated signal, thereby improving the detection capability of the assay, particularly with respect to low concentrations of toxicants.

    摘要翻译： 用于检测潜在毒性分析物的测定法利用具有信号产生代谢活性的真核细胞或原核细胞的制备物。 通过使用颗粒状固相吸附剂，可以显着改善这种测定的灵敏度。 硅胶，其可以预先与疑似有毒分析物或细胞试剂混合。 发现吸附剂 - 分析物组合或吸附剂 - 细胞试剂组合的存在导致产生的信号强度的降低的扩增，从而提高了测定的检测能力，特别是在低浓度下 的毒物。

    Method of processing and testing powdered samples using immunochromatographic strip tests
    8.
    发明授权
    Method of processing and testing powdered samples using immunochromatographic strip tests 失效
    使用免疫色谱条纹试验处理和测试粉末样品的方法

    公开(公告)号：US07354776B2

    公开(公告)日：2008-04-08

    申请号：US10149866

    申请日：2000-12-14

    申请人： Tara Ann Kennedy ,  Alan Bruce McQuillin

    发明人： Tara Ann Kennedy ,  Alan Bruce McQuillin

    IPC分类号： G01N33/538

    CPC分类号： G01N33/558 ,  G01N33/68 ,  G01N2033/0091 ,  Y10S435/805 ,  Y10S435/97 ,  Y10S436/807 ,  Y10S436/81 ,  Y10T436/25

    摘要： A method and kit for processing and testing powdered samples are provided herein. The powdered sample is combined with a fluid to produce a slurry or liquid suspension, and the slurry is contacted with an immunochromatographic test strip containing detectable reagents that are immunoreactive with an analyte to be detected in the sample. The method is particularly useful for the analysis of agricultural products or crops, such as the identification of recombinant grains.

    摘要翻译： 本文提供了一种加工和测试粉末样品的方法和试剂盒。 将粉末状样品与流体混合以产生浆液或液体悬浮液，并将浆液与含有可与样品中待检测分析物免疫反应的可检测试剂的免疫色谱测试条接触。 该方法对农产品或作物的分析特别有用，例如重组颗粒的鉴定。

    Compositions and Methods for the Detection of Water Treatment Polymers
    9.
    发明申请
    Compositions and Methods for the Detection of Water Treatment Polymers 有权
    组合物和水处理聚合物检测方法

    公开(公告)号：US20080062417A1

    公开(公告)日：2008-03-13

    申请号：US11852825

    申请日：2007-09-10

    申请人： James W. Stave ,  Matthew H. Knight

    发明人： James W. Stave ,  Matthew H. Knight

    IPC分类号： G01J3/44

    CPC分类号： G01N21/65 ,  C02F1/008 ,  C02F1/5209 ,  G01J3/44 ,  G01N21/658 ,  G01N33/1826 ,  G01N2021/653

    摘要： Compositions and methods utilizing Raman Spectroscopy to detect and determine, directly or indirectly, the concentration of water treatment polymers in water or methods for measuring or quantifying the amount of water treatment polymer in a sample, such as an industrial, commercial, or municipal water sample, are provided. The compositions contain water treatment polymers that have been modified to include one or more Raman-active functional groups. The methods utilize Raman spectroscopy to detect the presence or amount of water treatment polymer either directly or indirectly. The method provides the ability to detect or measure the amount of active water treatment polymer remaining in the sample.

    摘要翻译： 使用拉曼光谱法的组合物和方法直接或间接地检测和测定水中水处理聚合物的浓度或测量或定量样品中的水处理聚合物的量的方法，例如工业，商业或城市水样品 ，提供。 该组合物含有经过改性以包括一个或多个拉曼活性官能团的水处理聚合物。 该方法利用拉曼光谱法直接或间接地检测水处理聚合物的存在或量。 该方法提供检测或测量残留在样品中的活性水处理聚合物的量的能力。