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公开(公告)号：US20230200883A1
公开(公告)日：2023-06-29
申请号：US17879222
申请日：2022-08-02
Applicant: Fractyl Health, Inc.
Inventor： Jay Caplan , Harith Rajagopalan , J. Christopher Flaherty
IPC: A61B18/14
CPC classification number: A61B18/14 , A61B18/1492 , A61B2018/00494
Abstract: A device for ablating target tissue of a patient with electrical energy is provided. An elongate shaft includes a proximal portion and a distal portion, and a radially expandable element is attached to the distal portion. An ablation element for delivering electrical energy to target tissue is mounted to the radially expandable element. The device can be constructed and arranged to ablate the duodenal mucosa of a patient while avoiding damage to the duodenal adventitial tissue. Systems and methods of treating target tissue are also provided.
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公开(公告)号：US20220354571A1
公开(公告)日：2022-11-10
申请号：US17868076
申请日：2022-07-19
Applicant: Fractyl Health, Inc.
Inventor： Jay Caplan , Harith Rajagopalan , Mark A. Manasas , Christopher James Kadamus , Andrew Coats , Philip S. Levin , J. Christopher Flaherty
Abstract: A device for expanding tissue comprises at least one fluid delivery tube and at least one fluid delivery element in fluid communication with the at least one fluid delivery tube. The at least one fluid delivery tube comprises a proximal end, a distal end, and a lumen therebetween. The device is constructed and arranged to perform a near full circumferential expansion of luminal wall tissue. Systems and methods are also provided, including a system for expanding tissue layers and treating tissue proximate to the expanded tissue layers.
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公开(公告)号：US20220117658A1
公开(公告)日：2022-04-21
申请号：US17516503
申请日：2021-11-01
Applicant: Fractyl Health, Inc.
Inventor： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
Abstract: Systems, devices and methods treat target tissue to provide a therapeutic benefit to the patient. A tissue treatment device comprises a tissue treatment element constructed and arranged to treat target tissue, such as duodenal mucosa and/or submucosal tissue. Patients treated can safely eliminate or reduce their daily insulin intake.
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公开(公告)号：US11878128B2
公开(公告)日：2024-01-23
申请号：US17384421
申请日：2021-07-23
Applicant: Fractyl Health, Inc.
Inventor： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
IPC: A61B18/14 , A61M25/00 , A61B18/02 , A61F5/00 , A61B5/00 , A61B17/00 , A61B18/08 , A61B18/18 , A61M25/04 , A61N7/00 , A61B18/00 , A61B18/06 , A61B18/04 , A61N7/02 , A61B17/02 , A61B90/00 , A61B5/055 , A61B17/34 , A61B17/30 , A61B18/24
CPC classification number: A61M25/00 , A61B5/0036 , A61B5/0084 , A61B5/4255 , A61B5/4836 , A61B5/6852 , A61B5/6885 , A61B17/00234 , A61B18/02 , A61B18/082 , A61B18/1492 , A61B18/1815 , A61F5/0069 , A61F5/0079 , A61M25/04 , A61N7/00 , A61B5/0066 , A61B5/055 , A61B17/00491 , A61B17/0218 , A61B17/3478 , A61B18/06 , A61B18/24 , A61B2017/00004 , A61B2017/00022 , A61B2017/00199 , A61B2017/00269 , A61B2017/00818 , A61B2017/306 , A61B2018/00005 , A61B2018/00011 , A61B2018/00017 , A61B2018/0022 , A61B2018/00029 , A61B2018/00041 , A61B2018/00255 , A61B2018/00285 , A61B2018/00291 , A61B2018/00494 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00744 , A61B2018/00791 , A61B2018/00809 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/00863 , A61B2018/00875 , A61B2018/00982 , A61B2018/0212 , A61B2018/046 , A61B2018/1861 , A61B2090/395 , A61B2090/3908 , A61B2090/3933 , A61B2218/002 , A61B2505/05 , A61B2560/0431 , A61B2562/227 , A61M25/0082 , A61M2210/1053 , A61M2210/1057 , A61M2210/1071 , A61M2210/1408 , A61N7/022
Abstract: A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).
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公开(公告)号：US20230165621A1
公开(公告)日：2023-06-01
申请号：US17859137
申请日：2022-07-07
Applicant: Fractyl Health, Inc.
Inventor： Michael Biasella , Sara Morneau , Jay Caplan , Michelle Riches , Philip Levin , Ryan Cahill , Keith Boudreau , Harith Rajagopalan , Brendan Zarechian , Jeffrey Lesica , R. Maxwell Flaherty , J. Christopher Flaherty
IPC: A61B18/04
CPC classification number: A61B18/04 , A61B2018/00494
Abstract: Systems, devices and methods for performing medical procedures in the intestine of a patient are provided. A medical device for performing a treatment and/or a diagnostic procedure can include an elongate shaft assembly comprising at least a shaft assembly first section comprising a distal section of the shaft assembly, and a shaft assembly second section proximal to the first section, and a functional assembly positioned on the shaft assembly first section. Additional sections of the shaft assembly can be included, and each section can comprise a different construction, such as to achieve a different stiffness as described herein. Variable stiffness along the length of the shaft assembly can be provided to aid in translation of the device through the patient's GI tract (e.g. through the stomach and into the small intestine), as described herein.
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Patent Agency Ranking
公开(公告)号：US12201342B2
公开(公告)日：2025-01-21
申请号：US17864855
申请日：2022-07-14
Applicant: Fractyl Health, Inc.
Inventor： Philip S. Levin , Jay Caplan , Harith Rajagopalan , Mark A. Manasas , Andrew Coats , J. Christopher Flaherty
Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
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公开(公告)号：US12178502B2
公开(公告)日：2024-12-31
申请号：US17868076
申请日：2022-07-19
Applicant: Fractyl Health, Inc.
Inventor： Jay Caplan , Harith Rajagopalan , Mark A. Manasas , Christopher James Kadamus , Andrew Coats , Philip S. Levin , J. Christopher Flaherty
Abstract: A device for expanding tissue comprises at least one fluid delivery tube and at least one fluid delivery element in fluid communication with the at least one fluid delivery tube. The at least one fluid delivery tube comprises a proximal end, a distal end, and a lumen therebetween. The device is constructed and arranged to perform a near full circumferential expansion of luminal wall tissue. Systems and methods are also provided, including a system for expanding tissue layers and treating tissue proximate to the expanded tissue layers.
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公开(公告)号：US12089887B2
公开(公告)日：2024-09-17
申请号：US17192671
申请日：2021-03-04
Applicant: Fractyl Health, Inc.
Inventor： Jay Caplan , Philip S. Levin , Andrew Coats , Harith Rajagopalan , Mark A. Manasas , J. Christopher Flaherty
IPC: A61M25/10 , A61B18/00 , A61B18/04 , A61B18/06 , A61B17/00 , A61B18/02 , A61B18/14 , A61B18/24 , A61N7/02
CPC classification number: A61B18/04 , A61B18/06 , A61M25/1002 , A61B2017/00269 , A61B2018/00017 , A61B2018/0022 , A61B2018/00494 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/046 , A61B2018/048 , A61B18/1492 , A61B18/24 , A61M2025/105 , A61N7/022
Abstract: A device for ablating target tissue of a patient with an ablative fluid is provided. An elongate shaft includes a proximal portion and a distal portion, and at least one fluid delivery element is attached to the distal portion. The device can be configured to ablate the duodenal mucosa of a patient while avoiding damage to the duodenal adventitial tissue. Systems and methods of treating target tissue are also provided.
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公开(公告)号：US20230233250A1
公开(公告)日：2023-07-27
申请号：US17942914
申请日：2022-09-12
Applicant: Fractyl Health, Inc.
Inventor： Harith Rajagopalan , Jay Caplan , Craig M. Gardner , J. Christopher Flaherty
IPC: A61B18/14
CPC classification number: A61B18/1492 , A61B2018/00494
Abstract: Systems, devices and methods treat target tissue to provide a therapeutic benefit to the patient. A tissue treatment device comprises a tissue treatment element constructed and arranged to treat target tissue, such as duodenal mucosa and/or submucosal tissue. Patients treated can safely eliminate or reduce their daily insulin intake.
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公开(公告)号：US20230172649A1
公开(公告)日：2023-06-08
申请号：US17864855
申请日：2022-07-14
Applicant: Fractyl Health, Inc.
Inventor： Philip S. Levin , Jay Caplan , Harith Rajagopalan , Mark A. Manasas , Andrew Coats , J. Christopher Flaherty
CPC classification number: A61B18/082 , A61B18/04 , A61B2018/00023
Abstract: A system for treatment target tissue comprises an ablation device and an energy delivery unit. The ablation device comprises an elongate tube with an expandable treatment element. The system delivers a thermal dose of energy to treat the target tissue. Methods of treating target tissue are also provided.
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