公开(公告)号：US09375738B2

公开(公告)日：2016-06-28

申请号：US14390440

申请日：2013-04-05

Applicant: RPC Formatec GmbH

Inventor： Johannes Krieger

IPC: B05B11/06 ,  A61M11/06 ,  B05B7/00 ,  B05B7/14 ,  A61M15/00 ,  A61M11/00

CPC classification number: B05B11/061 ,  A61M11/007 ,  A61M11/06 ,  A61M15/0015 ,  A61M15/002 ,  A61M15/0045 ,  A61M2205/073 ,  B05B7/0012 ,  B05B7/1486 ,  B05B11/064 ,  B05B11/067

Abstract: A dispenser for discharging an in particular granular or powdery substance by blow-out, has a blow-out duct, and a suction line opening into the blow-out duct for sucking the substance into the blow-out duct. A positive air pressure can be built up in a duct section arranged upstream of the blow-out duct and closed in the direction of the blow-out duct by a valve opening in a pressure-dependent manner, for pressure-controlled formation of a blow-out stream in the blow-out duct. A method for emptying a substance reservoir having a freeze-dried substance sucks the substance out of the substance reservoir, using a suction air stream opening into a blowing stream, and discharges the substance. A sucking/blowing dispenser is used for emptying a substance reservoir having a freeze-dried substance.

Abstract translation: 用于通过吹出排出特定颗粒状或粉状物质的分配器具有吹出管道和通向吹出管道的吸入管线，用于将物质吸入吹出管道。 可以在布置在吹出管道的上游的管道部分中建立正的空气压力，并且以压力依赖的方式通过阀开口沿吹出管道的方向封闭，用于压力控制形成吹气 在吹出管道中流出。 将具有冷冻干燥物质的物质储存器排空的方法使用开放入吹送流的吸入空气流将物质从物质储存器中吸出，并排出物质。 抽吸/分配器用于清空具有冷冻干燥物质的物质储存器。

公开(公告)号：US09095867B2

公开(公告)日：2015-08-04

申请号：US13926568

申请日：2013-06-25

Applicant: Homax Products, Inc.

Inventor： John Kordosh ,  Randal W. Hanson

IPC: A62C11/00 ,  B05B11/00 ,  B05B1/12 ,  B05B1/16 ,  B05B7/14 ,  B05B11/06 ,  B05B1/30

CPC classification number: B05B11/3042 ,  B05B1/12 ,  B05B1/1654 ,  B05B1/169 ,  B05B1/3073 ,  B05B7/1486 ,  B05B11/061 ,  B05B11/062 ,  B05B11/3011

Abstract: A system for coating a target surface employs a bottle for containing the texture material and a spray pump assembly. A resilient member is supported by a pump housing to define an outlet opening. A collar member is supported by the pump housing. The resilient member is normally in an undeformed configuration in which the outlet opening defines a first cross-sectional area. Moving the collar member relative to the pump housing causes the collar member to act on the resilient member to deform the resilient member from the undeformed configuration to a deformed configuration in which the outlet opening defines a second cross-sectional area, where the second cross-sectional area is greater than the first cross-sectional area.

Abstract translation: 用于涂覆目标表面的系统采用用于容纳纹理材料的瓶子和喷雾泵组件。 弹性构件由泵壳体支撑以限定出口开口。 轴环部件由泵壳体支撑。 弹性构件通常处于未变形构造，其中出口开口限定第一横截面积。 使套环部件相对于泵壳体移动导致套环部件作用在弹性部件上，以使弹性部件从未变形的构造变形到变形构型，其中出口开口限定第二横截面积， 截面积大于第一横截面积。

公开(公告)号：US08251958B2

公开(公告)日：2012-08-28

申请号：US12965278

申请日：2010-12-10

Applicant: Vincent J. Sullivan ,  Ronald J. Pettis ,  John A. Mikszta ,  John P. Dekker, III ,  Wendy D. Woodley ,  Anjana Bhuta Wills ,  Matthew S. Ferriter ,  C. Robin Hwang

Inventor： Vincent J. Sullivan ,  Ronald J. Pettis ,  John A. Mikszta ,  John P. Dekker, III ,  Wendy D. Woodley ,  Anjana Bhuta Wills ,  Matthew S. Ferriter ,  C. Robin Hwang

IPC: A61M5/00 ,  A61M37/00 ,  A61M31/00

CPC classification number: A61M37/0015 ,  A61M11/003 ,  A61M11/008 ,  A61M15/0028 ,  A61M15/0031 ,  A61M15/0033 ,  A61M2202/064 ,  A61M2205/073 ,  A61M2205/075 ,  B05B11/061 ,  B05B11/062

Abstract: A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said chamber. At least one burstable membrane retains a medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.

Abstract translation: 用于皮内递送重组药物的方法和装置。 该装置包括与微型装置例如流体连通的腔室。 微型抛光机或一个或多个微针。 容纳药物的药筒可以位于所述腔室内。 至少一个可爆破膜在壳体内保持药物。 该方法包括以下步骤：将装置定位在患者皮肤上的递送部位，并通过从稀释剂源通过入口端口分配稀释剂来皮内施用药物，以破裂膜，重建药物并将重组的药物通过 皮肤的皮肤区域的微型装置。

公开(公告)号：US20090223516A1

公开(公告)日：2009-09-10

申请号：US12470557

申请日：2009-05-22

Applicant: Robert I. Connelly ,  Vincent J. Sullivan ,  Charles D. Shermer ,  Anjana Bhuta ,  Ronald J. Pettis

Inventor： Robert I. Connelly ,  Vincent J. Sullivan ,  Charles D. Shermer ,  Anjana Bhuta ,  Ronald J. Pettis

IPC: A61M15/00

CPC classification number: A61M15/0028 ,  A61M11/002 ,  A61M11/003 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/004 ,  A61M15/0041 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/075 ,  A61M2207/00 ,  B05B11/061 ,  B05B11/062

Abstract: A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.

Abstract translation: 用于向使用者施用药物的药物输送装置包括药物储存器和每个邻近储存器设置的入口和出口。 邻近入口设置的气室。 该装置包括可操作以将所述气室加压至少规定压力的加压机构。 第一个易碎膜延伸穿过入口端口，并将储存器与气室隔开。 第二个易碎膜延伸穿过出口。 当附加加压机构时，第一和第二膜中的至少一个响应于气室中的规定压力而爆裂，以允许气体流过入口和储存器并且将药物运送通过出口。

公开(公告)号：US07540285B2

公开(公告)日：2009-06-02

申请号：US11369596

申请日：2006-03-07

Applicant: Robert I. Connelly ,  Vincent J. Sullivan ,  Charles D. Shermer ,  Anjana Bhuta ,  Ronald J. Pettis

Inventor： Robert I. Connelly ,  Vincent J. Sullivan ,  Charles D. Shermer ,  Anjana Bhuta ,  Ronald J. Pettis

IPC: A61M15/00

CPC classification number: A61M15/0028 ,  A61M11/002 ,  A61M11/003 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/004 ,  A61M15/0041 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/075 ,  A61M2207/00 ,  B05B11/061 ,  B05B11/062

Abstract: A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port and a gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism to pressurize the gas chamber. The device also contains frangible membranes and may include a piercing member. In use, the frangible membranes in the device are responsive to pressure in the gas chamber and are either pierced or burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.

Abstract translation: 用于向使用者施用药物的药物输送装置包括药物储存器和入口端口以及邻近入口设置的出口和气室。 该装置包括用于对气室加压的加压机构。 该装置还包含易碎膜并且可以包括刺穿构件。 在使用中，装置中的易碎膜响应于气室中的压力，并且被刺穿或爆裂以允许气体流过入口和储存器并且将药物运送通过出口。

公开(公告)号：US20060150969A1

公开(公告)日：2006-07-13

申请号：US11369596

申请日：2006-03-07

Applicant: Robert Connelly ,  Vincent Sullivan ,  Charles Shermer ,  Anjana Bhuta ,  Ronald Pettis

Inventor： Robert Connelly ,  Vincent Sullivan ,  Charles Shermer ,  Anjana Bhuta ,  Ronald Pettis

IPC: A61M11/00

CPC classification number: A61M15/0028 ,  A61M11/002 ,  A61M11/003 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/004 ,  A61M15/0041 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/075 ,  A61M2207/00 ,  B05B11/061 ,  B05B11/062

Abstract: A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.

公开(公告)号：US06929005B2

公开(公告)日：2005-08-16

申请号：US09879517

申请日：2001-06-12

Applicant: Vincent J. Sullivan ,  Anjana Bhuta Wills ,  Lawrence A. Monahan ,  Michael W. Trull ,  Christopher J. Knors

Inventor： Vincent J. Sullivan ,  Anjana Bhuta Wills ,  Lawrence A. Monahan ,  Michael W. Trull ,  Christopher J. Knors

IPC: A61J1/06 ,  A61J7/00 ,  A61M11/06 ,  A61M15/00 ,  B05B11/06

CPC classification number: A61M15/0028 ,  A61M11/002 ,  A61M11/003 ,  A61M11/02 ,  A61M15/0025 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/004 ,  A61M15/0041 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/075 ,  A61M2207/00 ,  B05B11/061 ,  B05B11/062

Abstract: A medicament respiratory delivery device including a housing having a chamber, an inlet and an outlet generally coaxially aligned with the chamber, wherein the chamber includes a medicament cartridge having a body including a generally cylindrical passage extending through the opposed ends of the cartridge generally coaxially aligned with the inlet and outlet of the housing having thin burstable polyolefin membranes having a burst pressure of between 1.2 and 10 atmospheres stretched taut over the ends of the cartridge, such that fluid delivered to the inlet ruptures the membranes, entraining medicament contained within the cartridge passage which is delivered to the patient's respiratory system through the outlet. The method of forming the cartridge includes stretching out and bending a membrane to one end of the cartridge, preferably by heat bonding, filling the cartridge with a medicament and sealing the opposed end preferably with a second burstable membrane by stretching out a membrane over a convex surface and heat bonding.

Abstract translation: 一种药物呼吸递送装置，包括具有腔室，大体上与腔室同轴对准的入口和出口的壳体，其中所述腔室包括药剂盒，所述药剂盒具有主体，该主体包括大体上圆柱形的通道，该通道延伸穿过所述药筒的相对端， 壳体的入口和出口具有薄的可爆破的聚烯烃膜，其具有介于盒的端部之间拉伸的介于1.2和10个大气压之间的爆破压力，使得输送到入口的流体破裂膜，夹带在盒通道内的药剂 通过出口将其输送到患者的呼吸系统。 形成盒的方法包括：将膜延伸出并弯曲到盒的一端，优选通过热粘合，用药物填充盒，并优选用第二可爆膜密封相对端，通过在凸起 表面和热粘合。

公开(公告)号：US20050023295A1

公开(公告)日：2005-02-03

申请号：US10902517

申请日：2004-07-29

Applicant: Karl Tempfli

Inventor： Karl Tempfli

IPC: A61M15/00 ,  A61M15/08 ,  B05B11/02 ,  B05B11/06 ,  B65D81/32 ,  B67D5/52

CPC classification number: B05B11/02 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/08 ,  A61M2210/0618 ,  B05B11/061 ,  B65D81/325

Abstract: Dosing device with application rounded cone or top. A dosing device with an application top containing at least one application opening, as well as a supply device which, when operating, leads a first medium through at least one medium channel from a medium reservoir to the application opening is known. According to the invention, at least one discharge opening for at least one further medium is provided in the application top adjacent to the application opening and within the application top at least one flow channel for the at least one further medium leads to the discharge opening.

Abstract translation: 给药装置应用圆锥或顶部。 具有包含至少一个施加开口的施加顶部的计量装置以及当操作时将第一介质通过至少一个介质通道从介质储存器引导到施加开口的供应装置是已知的。 根据本发明，用于至少一个另外的介质的至少一个排出口设置在与施加开口相邻的施加顶部中，并且在施加顶部内，至少一个另外的介质的至少一个流动通道通向排出口。

公开(公告)号：US5388572A

公开(公告)日：1995-02-14

申请号：US143182

申请日：1993-10-26

Applicant: Paul Mulhauser ,  Jeffrey Karg ,  Thomas Foxen ,  Christopher J. Brooks

Inventor： Paul Mulhauser ,  Jeffrey Karg ,  Thomas Foxen ,  Christopher J. Brooks

IPC: B65D83/04 ,  A61M11/00 ,  A61M13/00 ,  A61M15/00 ,  B05B11/00 ,  B05B11/06 ,  B65D83/06 ,  A61M16/00 ,  B05D7/14 ,  B05D83/06

CPC classification number: B05B11/3091 ,  A61M11/02 ,  A61M15/0026 ,  A61M15/0045 ,  A61M15/0048 ,  A61M15/0075 ,  A61M15/0091 ,  B05B11/061 ,  A61M2202/064 ,  A61M2205/073

Abstract: A dry powder inhalator for delivering a precise dose of a medicament contains a mesh disc impregnated with a series of spaced, medicament doses about the disc periphery. The inhalator is armed by manually retracting a finger pull extending downwardly from the bottom of the inhalator housing or rotating the bottom of the housing. The user inserts a mouthpiece on the housing into the mouth and inhales. This causes a chamber in the housing under a diaphragm to evacuate, thereby pulling the diaphragm down onto a knock out lever. The pivoting of the lever enables release of a piston into a cylinder which first compresses, and then dispenses a reduced volume of air at high pressure in a burst up through the medicament disc. When the burst of air hits the impregnated disc, the dose is forced out of the mesh's interstices, producing a cloud of the drug in its powdered form, which is inhaled by the user.

Abstract translation: 用于递送精确剂量的药物的干粉吸入器包含浸渍有围绕盘周边的一系列间隔的药物剂量的网片盘。 通过手动收回从吸入器壳体的底部向下延伸的或者旋转壳体的底部的手指拉力来吸入吸入器。 用户将口罩插入外壳进入口腔并吸入。 这使得在隔膜下的壳体中的腔室被排出，从而将隔膜向下拉到敲击杆上。 杠杆的枢转使得活塞能够释放到气缸中，该气缸首先压缩，然后在高压下通过药物盘突发地分配减小体积的空气。 当爆裂的空气撞击浸渍的盘时，剂量被迫离开网状物的间隙，产生由粉末形式的药物的云，其由用户吸入。

公开(公告)号：US4119244A

公开(公告)日：1978-10-10

申请号：US778717

申请日：1977-03-17

Applicant: Peter Funke

Inventor： Peter Funke

IPC: B05B11/00 ,  B67D1/04 ,  F04B33/00 ,  F04B39/00 ,  F04F1/06 ,  G01F11/02 ,  B65D83/14

CPC classification number: F04B39/0016 ,  B05B11/061 ,  B67D1/0425 ,  F04B33/00 ,  F04F1/06 ,  G01F11/028

Abstract: An arrangement has a hand-operated piston pump mountable on a neck of a bottle, and having a first portion outwardly embracing the neck and a second portion inwardly extending into the neck of the bottle. The first portion of the piston pump overlaps the neck over at least a part of its height and is supported by the same. The second portion is formed as a ring-shaped collar. For sealingly connecting the second portion to the neck of the bottle, there is provided as a rubber stopper located between the outer surface of the second portion of the piston pump and the inner surface of the neck of the bottle. The second portion may be provided with an inner thread which can mesh with an outer thread of the neck serving for screwing on a threaded cap. A member is further provided for detachably connecting a drink container to the arrangement so that the liquid withdrawing from the bottle travels directly into the container. The piston pump is a compressed air-operated pump and has an interruptable system of channels provided with an air inlet valve and an air outlet valve. The air inlet valve is formed on a piston of the piston pump, and the air outlet valve is formed on the second piston of the latter.

Abstract translation: 一种装置具有可安装在瓶颈上的手动活塞泵，并且具有向外包围颈部的第一部分和向内延伸进瓶颈部的第二部分。 活塞泵的第一部分在其高度的至少一部分上与颈部重叠并且由其支撑。 第二部分形成为环形领。 为了将第二部分密封地连接到瓶的颈部，设置有位于活塞泵的第二部分的外表面和瓶颈的内表面之间的橡胶塞。 第二部分可以设置有可以与颈部的外螺纹啮合的内螺纹，用于螺纹拧在螺纹盖上。 进一步设置用于将饮料容器可拆卸地连接到该装置的构件，使得从瓶中取出的液体直接进入容器。 活塞泵是一种压缩空气操作的泵，并且具有可中断的通道系统，该系统具有进气阀和排气阀。 进气阀形成在活塞泵的活塞上，空气出口阀形成在后者的第二活塞上。