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公开(公告)号：US20130304089A1
公开(公告)日：2013-11-14
申请号：US13792456
申请日：2013-03-11
Applicant: QUEST PHARMATECH INC.
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
IPC: A61K41/00
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
Abstract translation: 本发明涉及苝醌衍生物，其立体异构体和阻转异构体的化合物。 这些化合物在光动力学或儿子动力学治疗中可以特别用作光敏剂或超声敏剂。 本发明还涉及在光动力学和/或超声动力学治疗中使用这些化合物的各种方法。 所述化合物还可用作治疗各种过度增殖性疾病的治疗剂。
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公开(公告)号：US08747811B2
公开(公告)日：2014-06-10
申请号：US14012865
申请日：2013-08-28
Applicant: Quest Pharmatech, Inc.
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
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公开(公告)号：US08758725B2
公开(公告)日：2014-06-24
申请号：US13792456
申请日：2013-03-11
Applicant: Quest Pharmatech Inc.
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
Abstract translation: 本发明涉及苝醌衍生物，其立体异构体和阻转异构体的化合物。 这些化合物在光动力学或儿子动力学治疗中可以特别用作光敏剂或超声敏剂。 本发明还涉及在光动力学和/或超声动力学治疗中使用这些化合物的各种方法。 所述化合物还可用作治疗各种过度增殖性疾病的治疗剂。
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公开(公告)号：US20100210654A1
公开(公告)日：2010-08-19
申请号：US12530228
申请日：2008-03-07
Applicant: Christa E. Müller , Younis Baqi
Inventor： Christa E. Müller , Younis Baqi
IPC: A61K31/53 , C07C50/20 , A61K31/136 , C07D251/42 , C07D239/42 , A61K31/505 , A61P9/10 , A61P9/00
CPC classification number: C07C309/53 , C07C229/74 , C07C309/46 , C07C323/37 , C07C2603/24 , C07D251/42 , C07D251/44 , C07D251/46 , C07D251/50
Abstract: The present invention relates to novel P2Y12 receptor antagonists useful for treating, alleviating and/or preventing diseases and disorders related to P2Y12 receptor function as well as pharmaceutical compositions comprising such compounds and methods for preparing such compounds. The present invention is further directed to the use of these compounds, alone or in combination with other therapeutic agents, for the alleviation, prevention and/or treatment of diseases and disorders, especially the use as antithrombotic agents for inhibiting platelet aggregation.
Abstract translation: 本发明涉及可用于治疗，减轻和/或预防与P2Y12受体功能相关的疾病和病症的新型P2Y12受体拮抗剂以及包含这些化合物的药物组合物和制备这些化合物的方法。 本发明还涉及这些化合物单独或与其它治疗剂组合用于减轻，预防和/或治疗疾病和病症，特别是用作抗血栓形成剂用于抑制血小板聚集的用途。
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5.发明申请Cu-Mediated Annulation for the Production of 1-Amino-2-Naphthalenecarboxylic Acid Derivatives 有权铜介导的1-氨基-2-萘羧酸衍生物的制备公开(公告)号：US20150011781A1
公开(公告)日：2015-01-08
申请号：US14371059
申请日：2013-01-10
Applicant: Council of Scientific & Industrial Research
IPC: C07C227/12 , C07C229/70 , C07C229/68 , C07D317/70
CPC classification number: C07C227/12 , C07C229/68 , C07C229/70 , C07C229/74 , C07C2603/26 , C07D317/70
Abstract: Invention provides a cheaper and practical protocol for the construction of a wide variety of 1-Amino-2-naphthalene-carboxylic acid derivatives and their structural analogues that proceeds with high yields in a single step via intramolecular cascade cyano ene reaction.
Abstract translation: 本发明提供了用于构建各种各样的1-氨基-2-萘甲酸衍生物及其结构类似物的便宜且实用的方案，其通过分子内级联氰基烯反应在单步中以高产率进行。
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Patent Agency Ranking
公开(公告)号：US20140072512A1
公开(公告)日：2014-03-13
申请号：US14012865
申请日：2013-08-28
Applicant: Quest Pharmatech, Inc.
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
IPC: C07C229/74 , A61K41/00 , C07D241/38 , C07D209/94
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
Abstract translation: 本发明涉及苝醌衍生物，其立体异构体和阻转异构体的化合物。 这些化合物在光动力学或儿子动力学治疗中可以特别用作光敏剂或超声敏剂。 本发明还涉及在光动力学和/或超声动力学治疗中使用这些化合物的各种方法。 所述化合物还可用作治疗各种过度增殖性疾病的治疗剂。
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7.发明授权Cu-mediated annulation for the production of 1-amino-2-naphthalenecarboxylic acid derivatives 有权Cu介导的1-氨基-2-萘甲酸衍生物的制备公开(公告)号：US09233911B2
公开(公告)日：2016-01-12
申请号：US14371059
申请日：2013-01-10
Applicant: Council of Scientific & Industrial Research
IPC: C07C227/12 , C07C229/68 , C07C229/70 , C07C229/74 , C07D317/70
CPC classification number: C07C227/12 , C07C229/68 , C07C229/70 , C07C229/74 , C07C2603/26 , C07D317/70
Abstract: Invention provides a cheaper and practical protocol for the construction of a wide variety of 1-Amino-2-naphthalene-carboxylic acid derivatives and their structural analogues that proceeds with high yields in a single step via intramolecular cascade cyano ene reaction.
Abstract translation: 本发明提供了用于构建各种各样的1-氨基-2-萘甲酸衍生物及其结构类似物的便宜且实用的方案，其通过分子内级联氰基烯反应在单步中以高产率进行。
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公开(公告)号：US08506931B2
公开(公告)日：2013-08-13
申请号：US11722423
申请日：2006-07-28
Applicant: Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
IPC: A61K49/00
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
Abstract translation: 本发明涉及苝醌衍生物，其立体异构体和阻转异构体的化合物。 这些化合物在光动力学或儿子动力学治疗中可以特别用作光敏剂或超声敏剂。 本发明还涉及在光动力学和/或超声动力学治疗中使用这些化合物的各种方法。 所述化合物还可用作治疗各种过度增殖性疾病的治疗剂。
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公开(公告)号：US20100047178A1
公开(公告)日：2010-02-25
申请号：US11722423
申请日：2006-07-28
Applicant: Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
Inventor： Sanjay K. Sharma , Thomas Woo , Selvaraj Naicker
IPC: A61K49/06 , C07D487/00 , A61K31/403 , C07C211/57 , A61K31/135 , C07D241/36 , A61K31/498 , A61K39/395 , A61K38/02 , A61K9/127 , A61K49/00 , A61P35/00 , G01N33/53
CPC classification number: C07C229/74 , A61K8/415 , A61K8/492 , A61K41/0033 , A61K41/0057 , A61K49/00 , A61K2800/434 , A61Q9/04 , C07C225/32 , C07C2603/54 , C07D209/94 , C07D241/38 , C07D241/52
Abstract: The present invention relates to compounds which are perylenequinone derivatives, their stereoisomers and atropisomers. These compounds can be particularly useful as photosensitizers or sononsensitizers in photodynamic or sonodynamic therapy. The invention also relates to various methods for using these compounds in photodynamic and/or sonodynamic therapy. The compounds also are useful as therapeutic agents for treating various hyperproliferative disorders.
Abstract translation: 本发明涉及苝醌衍生物，其立体异构体和阻转异构体的化合物。 这些化合物在光动力学或儿子动力学治疗中可以特别用作光敏剂或超声敏剂。 本发明还涉及在光动力学和/或超声动力学治疗中使用这些化合物的各种方法。 所述化合物还可用作治疗各种过度增殖性疾病的治疗剂。
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公开(公告)号：US5864048A
公开(公告)日：1999-01-26
申请号：US903660
申请日：1997-07-31
Applicant: Guido Di Napoli
Inventor： Guido Di Napoli
IPC: A61K20060101 , A61K31/165 , A61K31/22 , A61K31/235 , C07C20060101 , C07C50/26 , C07C65/40 , C07C67/31 , C07C67/313 , C07C69/017 , C07C69/90 , C07C69/95 , C07C205/25 , C07C205/42 , C07C229/52 , C07C229/66 , C07C229/74 , C07C233/54 , C07C235/84 , C07C245/20
CPC classification number: C07C69/95 , A61K8/355 , A61Q19/00 , C07C229/66 , C07C229/74 , C07C233/33 , C07C235/84 , C07C69/18 , C07C2103/24
Abstract: The present description relates to new anthraquinone-derivatives endowed with inhibitory activity of the serine proteinase enzymes, useful for the treatment of rheumatoid arthritis, acute respiratory syndrome of adult, and pulmonary emphysema, and to new processes for the preparation of rhein derivatives.
Abstract translation: 本说明书涉及可用于治疗类风湿性关节炎，成人急性呼吸综合征和肺气肿的丝氨酸蛋白酶抑制活性的新型蒽醌衍生物以及制备大黄酸衍生物的新方法。
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