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1.发明申请Valencene Synthase Polypeptides, Encoding Nucleic Acid Molecules And Uses Thereof 有权Valencene合酶多肽，编码核酸分子及其用途公开(公告)号：US20150007368A1
公开(公告)日：2015-01-01
申请号：US13999598
申请日：2014-03-11
申请人： Dayal Saran , Grace Eunyoung Park
发明人： Dayal Saran , Grace Eunyoung Park
CPC分类号： C12N9/88 , C12N15/8243 , C12P5/007 , C12P7/26 , C12Y402/03073
摘要： Provided are valencene synthase polypeptides, nucleic acid molecules encoding the valencene synthases, host cells containing the nucleic acids and methods for producing products whose production is catalyzed by the polypeptides. Also provided are methods for producing valencene and nootkatone.
摘要翻译： 提供的是戊烯合酶多肽，编码戊烯合成酶的核酸分子，含有核酸的宿主细胞和用于产生其多肽产生的产物的方法。 还提供了生产戊烯和诺卡酮的方法。
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公开(公告)号：US20140356926A1
公开(公告)日：2014-12-04
申请号：US14121245
申请日：2014-08-13
申请人： Joseph Chappell , Bryan Greenhagen
发明人： Joseph Chappell , Bryan Greenhagen
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03047 , C12Y402/03073
摘要： The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention.
摘要翻译： 本发明涉及倍半萜合酶及其生产和使用的方法。 特别地，本发明提供了包含编码至少一个CVS的柑橘类戊烯合酶（CVS）的核苷酸序列的核酸。 本发明还提供了包含编码形成CVS的1级和2级结构域的氨基酸残基的核苷酸序列的核酸。 本发明还提供制备和使用本发明的核酸和氨基酸的方法。
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公开(公告)号：US20180327723A1
公开(公告)日：2018-11-15
申请号：US15774134
申请日：2016-11-14
申请人： Evolva SA
发明人： Dayal Saran , Jorgen Hansen , Philippe Prochasson , Patrick Roussel , Laura Occhipinti , Alexei Ouspenski , Sumire Honda Malca
CPC分类号： C12N9/1048 , A01N43/16 , A23L29/035 , A61Q13/00 , C12N15/70 , C12P19/44 , C12Y106/02004 , C12Y204/00 , C12Y402/03073
摘要： The invention relates to methods for producing glycosylated nootkatol. In particular, a recombinant host comprising a gene encoding a UDP-glycosyltransferase polypeptide capable of glycosylating nootkatol is disclosed. Glycosylation of nootkatol detoxifies nootkatol, allowing for greater production of (glycosylated-)nootkatol, a precursor of nootkatone, and therefore greater production of nootkatone. The invention also relates to methods of converting non-toxic, glycosylated nootkatol produced by a recombinant host to nootkatol, wherein the nootkatol can subsequently be converted to large quantities of nootkatone to be used in flavorings, perfumes, and/or insect repellents.
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公开(公告)号：US20140075600A1
公开(公告)日：2014-03-13
申请号：US13516545
申请日：2010-12-15
申请人： Jihane Achkar , Theodorus Sonke , Martinus Julius Beekwilder , Hendrik Jan Bouwmeester , Hendrik Jan Bosch
发明人： Jihane Achkar , Theodorus Sonke , Martinus Julius Beekwilder , Hendrik Jan Bouwmeester , Hendrik Jan Bosch
CPC分类号： C12N9/88 , C12P5/007 , C12P7/26 , C12P7/40 , C12Y402/03073
摘要： The present invention relates to a valencene synthase, to a nucleic acid encoding such valencene synthase, to a host cell comprising said encoding nucleic acid sequence and to a method for preparing valencene, comprising converting farnesyl diphosphate to valencene in the presence of a valencene synthase according to the invention.
摘要翻译： 本发明涉及对于包含所述编码核酸序列的宿主细胞的编码这种戊烯合酶的核酸的戊烯合成酶和用于制备戊烯的方法，所述方法包括在戊烯合成酶存在下将法呢基二磷酸酯转化为戊烯， 涉及本发明。
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公开(公告)号：US10000749B2
公开(公告)日：2018-06-19
申请号：US13999598
申请日：2014-03-11
申请人： Evolva, Inc.
发明人： Dayal Saran , Grace Eunyoung Park
CPC分类号： C12N9/88 , C12N15/8243 , C12P5/007 , C12P7/26 , C12Y402/03073
摘要： Provided are valencene synthase polypeptides, nucleic acid molecules encoding the valencene synthases, host cells containing the nucleic acids and methods for producing products whose production is catalyzed by the polypeptides. Also provided are methods for producing valencene and nootkatone.
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6.发明申请EXPRESSION CONSTRUCTS AND USES THEREOF IN THE PRODUCTION OF TERPENOIDS IN YEAST 审中-公开表达结构及其在YEAST生产季戊四醇酯中的应用公开(公告)号：US20130302861A1
公开(公告)日：2013-11-14
申请号：US13893367
申请日：2013-05-14
IPC分类号： C12P5/00
CPC分类号： C12P5/007 , C07K2319/07 , C12N9/1085 , C12N9/88 , C12Y402/03024 , C12Y402/03073
摘要： A method of producing at least one terpene in a yeast cell is disclosed. The method comprises exogenously expressing within the mitochondria of the yeast cell or directing localization thereto a terpene synthase.
摘要翻译： 公开了一种在酵母细胞中生产至少一种萜烯的方法。 该方法包括在酵母细胞的线粒体内外源表达或引导其定位于萜烯合酶。
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公开(公告)号：US20100216186A1
公开(公告)日：2010-08-26
申请号：US12259497
申请日：2008-10-28
申请人： Joseph Chappell , Bryan Greenhagen
发明人： Joseph Chappell , Bryan Greenhagen
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03047 , C12Y402/03073
摘要： The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention.
摘要翻译： 本发明涉及倍半萜合酶及其生产和使用的方法。 特别地，本发明提供了包含编码至少一个CVS的柑橘类戊烯合酶（CVS）的核苷酸序列的核酸。 本发明还提供了包含编码形成CVS的1级和2级结构域的氨基酸残基的核苷酸序列的核酸。 本发明还提供制备和使用本发明的核酸和氨基酸的方法。
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公开(公告)号：US20150079649A1
公开(公告)日：2015-03-19
申请号：US14127630
申请日：2012-06-21
申请人： Theodorus Sonke , Rene M. De Jong
发明人： Theodorus Sonke , Rene M. De Jong
CPC分类号： C12N9/88 , C07K16/40 , C12P7/26 , C12Y402/03073
摘要： The present invention relates to a novel valencene synthase, to a nucleic acid encoding such valencene synthase, to a host cell comprising said encoding nucleic acid sequence and to a method for preparing valencene, comprising converting farnesyl diphosphate to valencene in the presence of a valencene synthase according to the invention.
摘要翻译： 本发明涉及一种新型的戊烯合酶，涉及编码这种戊烯合酶的核酸，包含所述编码核酸序列的宿主细胞和一种制备戊烯的方法，包括在戊烯合成酶存在下将法呢基二磷酸酯转化为戊烯 根据本发明。
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公开(公告)号：US20120196340A1
公开(公告)日：2012-08-02
申请号：US13385794
申请日：2012-03-06
申请人： Joseph Chappell , Bryan Greenhagen
发明人： Joseph Chappell , Bryan Greenhagen
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03047 , C12Y402/03073
摘要： The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention.
摘要翻译： 本发明涉及倍半萜合酶及其生产和使用的方法。 特别地，本发明提供了包含编码至少一个CVS的柑橘类戊烯合酶（CVS）的核苷酸序列的核酸。 本发明还提供了包含编码形成CVS的1级和2级结构域的氨基酸残基的核苷酸序列的核酸。 本发明还提供制备和使用本发明的核酸和氨基酸的方法。
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公开(公告)号：US20060218661A1
公开(公告)日：2006-09-28
申请号：US10899356
申请日：2004-07-26
申请人： Joe Chappell , Bryan Greenhagen
发明人： Joe Chappell , Bryan Greenhagen
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03047 , C12Y402/03073
摘要： The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention.
摘要翻译： 本发明涉及倍半萜合酶及其生产和使用的方法。 特别地，本发明提供了包含编码至少一个CVS的柑橘类戊烯合酶（CVS）的核苷酸序列的核酸。 本发明还提供了包含编码形成CVS的1级和2级结构域的氨基酸残基的核苷酸序列的核酸。 本发明还提供制备和使用本发明的核酸和氨基酸的方法。
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