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公开(公告)号：US07252802B2
公开(公告)日：2007-08-07
申请号：US10204062
申请日：2001-02-19
申请人： John Anthony Bonnard
发明人： John Anthony Bonnard
IPC分类号： G01N30/00
CPC分类号： G01N25/26 , G01N25/4806
摘要： An apparatus and method for igniting a sample in a calorimeter. A heating element is used to ignite a solid or liquid substance inside the calorimeter, and the burning substance is allowed to move into contact with a sample in a crucible to ignite the sample.
摘要翻译： 用于在量热计中点燃样品的装置和方法。 加热元件用于点燃量热计内的固体或液体物质，并使燃烧物质与坩埚中的样品接触以点燃样品。
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公开(公告)号：US06644136B1
公开(公告)日：2003-11-11
申请号：US09796733
申请日：2001-03-02
IPC分类号： G01N100
CPC分类号： G01N25/4806 , G01N35/0099 , G01N35/025 , G01N2035/00356 , G01N2035/0465
摘要： The invention relates to a sample tray to be used by an automatic sampler having a sample arm. According to an aspect, the sample tray includes wells that can be accessed by a sample arm along a common arc of rotation, without moving the sample arm in and out. According to another aspect, the sample tray has several concentric rows of wells for holding sample pans and reference pans. Each row of wells lies along an inner circumference of the sample tray. The rows are placed so that when the sample tray is rotated, every well can be located on a common arc of rotation relative to a sample arm. According to another aspect, a well in a sample tray is configured with a pan receiving area and finger receiving areas. Gripper fingers can be extended into the finger receiving areas to access pans of different sizes.
摘要翻译： 本发明涉及一种由具有样品臂的自动采样器使用的样品盘。 根据一个方面，样品托盘包括可以沿着共同的旋转圆弧由样品臂访问的孔，而不移动样品臂进出。 根据另一方面，样品托盘具有几个同心排的孔，用于保持样品盘和参考盘。 每排井位于样品托盘的内圆周上。 这些行被放置成使得当样品托盘旋转时，每个孔可以位于相对于样品臂的公共旋转弧上。 根据另一方面，样品托盘中的孔配置有盘接收区域和手指接收区域。 手指可以延伸到手指接收区域以访问不同尺寸的平底锅。
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公开(公告)号：US20020034210A1
公开(公告)日：2002-03-21
申请号：US09961872
申请日：2001-09-24
IPC分类号： G01N025/00 , G01K017/00
CPC分类号： G01K17/00 , G01N25/4806
摘要： A calorimeter that includes a sample cell, a reference cell, a pressure system that applies a variable pressure to the sample cell, and a pressure controller that controls the pressure applied by the pressure system to the sample cell. By applying identical pressure perturbations to both the sample and reference cells over a range of temperatures, the calorimeter can be used to accurately calculate both the thermal coefficient of expansion of various substances, and the volume change of molecules undergoing a structural transition.
摘要翻译： 包括样品池，参比池，向样品池施加可变压力的压力系统的量热计，以及控制由压力系统施加到样品池的压力的压力控制器。 通过在一定温度范围内对样品和参比细胞施加相同的压力扰动，量热计可用于精确地计算各种物质的热膨胀系数和经历结构转变的分子的体积变化。
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公开(公告)号：US5669554A
公开(公告)日：1997-09-23
申请号：US561194
申请日：1995-11-21
CPC分类号： G05D22/02 , B01F3/022 , G01N25/4806
摘要： The humidity of the atmosphere contacting a sample and the water vapor partial pressure are program controlled and measured in a device having: a sample chamber which is provided with an inlet and an outlet for water vapor and which is capable of controlling a feedback temperature along with the sample stored therein; a warm water chamber for generating saturated water vapor pressure which has a gas inlet and an outlet connected to a pipe and which is capable of controlling the feedback temperature; a humidity program function generator for outputting a target humidity value for the sample chamber for each input time interval; a memory for storing a temperature-saturated water vapor pressure curve; and a calculator for calculating a control target temperature for the warm water chamber for generating the saturated water vapor pressure on the basis of the sample chamber target temperature output from a temperature program function generator, sample chamber target humidity of the sample chamber output from the humidity program function generator and the temperature-saturated water vapor pressure curve.
摘要翻译： 接触样品的气氛和水蒸气分压的湿度在具有：具有水蒸气入口和出口的样品室的装置中进行程序控制和测量，该样品室能够控制反馈温度以及 样品存储在其中; 用于产生饱和水蒸汽压的温水室，其具有连接到管道的气体入口和出口，并且能够控制反馈温度; 湿度程序功能发生器，用于在每个输入时间间隔内输出样品室的目标湿度值; 用于存储温度饱和水蒸汽压力曲线的记忆体; 以及计算器，用于基于从温度程序函数发生器输出的样品室目标温度，从湿度输出的样品室的样品室目标湿度，计算用于产生饱和水蒸气压的温水室的控制目标温度 程序功能发生器和温度饱和水蒸汽压力曲线。
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公开(公告)号：US10082500B2
公开(公告)日：2018-09-25
申请号：US14626885
申请日：2015-02-19
CPC分类号： G01N33/54306 , B01L3/502784 , B01L7/52 , B01L2200/147 , B01L2300/0636 , B01L2300/0645 , B01L2300/0819 , B01L2300/0867 , B01L2300/0896 , B01L2300/1883 , G01K17/006 , G01N25/4806 , G01N33/54373
摘要： One aspect of the present disclosure relates to a calorimeter for detecting the presence of a target analyte in a fluid sample. The calorimeter can include a support structure, a hermetically-sealed, thermally decoupled central reaction zone associated with the support structure, at least one droplet transport region, and detection electronics. The at least one droplet transport region can be associated with the support structure and configured to merge a reagent droplet with a sample droplet including the fluid sample to form a reaction droplet in the central reaction zone. The detection electronics can be in electrical and/or thermal communication with the central reaction zone and associated with the support structure. The calorimeter can be configured to detect a heat of reaction produced by a reaction event between the target analyte and a capture reagent upon formation of the reaction droplet.
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6.发明申请SYSTEMS AND METHODS FOR SELECTIVE SENSING AND SELECTIVE THERMAL HEATING USING NANOSTRUCTURES 审中-公开使用纳米结构的选择性感测和选择性热加热的系统和方法公开(公告)号：US20160123911A1
公开(公告)日：2016-05-05
申请号：US14530231
申请日：2014-10-31
申请人： Elwha LLC
发明人： Kenneth G. Caldeira , Peter L. Hagelstein , Roderick A. Hyde , Edward K.Y. Jung , Jordin T. Kare , Nathan P. Myhrvold , David Schurig , Clarence T. Tegreene , Thomas Allan Weaver , Charles Whitmer , Lowell L. Wood, JR.
CPC分类号： H05B3/20 , G01K7/16 , G01K11/18 , G01K17/006 , G01N25/4806 , H05B1/0227 , H05B3/145 , H05B2214/04
摘要： Various methods for sensing and/or heating that utilize nanostructures or carbon structures, such as nanotubes, nanotube meshes, or graphene sheets, are disclosed. In some methods, at least a pair of contacts are electrically coupled with a given nanostructure or carbon structure to sense a change or to pass a current for heating.
摘要翻译： 公开了用于感测和/或加热利用纳米结构或碳结构的各种方法，例如纳米管，纳米管网或石墨烯片。 在一些方法中，至少一对触点与给定的纳米结构或碳结构电耦合以感测变化或通过用于加热的电流。
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公开(公告)号：US20130029851A1
公开(公告)日：2013-01-31
申请号：US13481363
申请日：2012-05-25
CPC分类号： G01N25/4806 , B01L3/5027
摘要： A calorimeter device includes various components located on a common substrate. A first (calorimeter) integrated chip device is located on the substrate. This first device has a first microfluidic channel that has first side and a second side. A first heat sensing circuit is located on the first side of the first channel and a second heat sensing circuit is located on the second side of the channel, opposite the first side and facing the first heat sensing circuit. A second integrated chip device is located on the substrate and proximal to the first device. The second device includes a second microfluidic channel having a fourth side and fifth side. A third heat sensing circuit is located on the third side of the second channel. A fourth heat sensing circuit is located on the fourth side of the channel, opposite the third side and facing the third heat sensing circuit.
摘要翻译： 量热器装置包括位于公共基板上的各种部件。 第一（量热计）集成芯片器件位于衬底上。 该第一装置具有第一微流体通道，其具有第一侧和第二侧。 第一热感测电路位于第一通道的第一侧上，并且第二热感测电路位于通道的第二侧上，与第一侧相对并且面向第一热感测电路。 第二集成芯片器件位于衬底上并且靠近第一器件。 第二装置包括具有第四侧和第五侧的第二微流体通道。 第三热感测电路位于第二通道的第三侧。 第四热感测电路位于通道的第四侧，与第三侧相对并面对第三热感应电路。
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公开(公告)号：US20080247441A1
公开(公告)日：2008-10-09
申请号：US11815776
申请日：2006-02-22
申请人： Giuseppe Salvetti , Elpidio Tombari , Carlo Ferrari , Luciano Lepori , Roberto Ambrosetti , Domenico Ricci , Alessandro Barbini , Luca Gasperini , Maria Rosaria Tine , Luca Bernazzani , Enrico Matteoli , Fabio Papucci
发明人： Giuseppe Salvetti , Elpidio Tombari , Carlo Ferrari , Luciano Lepori , Roberto Ambrosetti , Domenico Ricci , Alessandro Barbini , Luca Gasperini , Maria Rosaria Tine , Luca Bernazzani , Enrico Matteoli , Fabio Papucci
IPC分类号： G01K17/00
CPC分类号： G01N25/4806 , G01K17/00
摘要： A structure of calorimeter provides a calorimetric head (1) comprising a calorimetric cell (10) suitable for receiving a sample holding container (20) containing a sample (25) to examine. The cell (10) is arranged according to a first shield (3), or active shield. Outside the active shield (3) a second shield (4), or dynamical shield is present, which comprises a cylindrical hollow body arranged around the active shield (3) for all its length in order to provide a space (5) of determined size. Outside the active shield a thermal bath is present (not shown) at a temperature lower than the first and the second shield (3,4). The dynamic shield (4) allows an effective adjustment of the heat flux through the active shield (3) during calorimetric measures by limiting the heat flux same. In fact, in operative conditions the dynamic shield acts as thermal flywheel and keeps constant the heat flux coming from the active shield (3). More in detail, the presence of the dynamic shield (4) ensures the reduction of the temperature gradient on the active shield (3) and then on the cell (10) containing the sample (20). Furthermore, by keeping the dynamic shield (4) at a suitable temperature difference from the active shield (3), the temperature can be controlled with much less electric power than it would be necessary if the active shield (3) exchanged heat directly with the thermal bath.
摘要翻译： 热量计的结构提供了一种量热头（1），其包括适于接收包含待检样品（25）的样品保持容器（20）的量热池（10）。 电池（10）根据第一屏蔽（3）或主动屏蔽来布置。 在主动屏蔽（3）的外部，存在第二屏蔽（4）或动力屏蔽，其包括围绕主动屏蔽（3）全部长度布置的圆柱形中空体，以便提供确定尺寸的空间（5） 。 在主动屏蔽之外，在低于第一和第二屏蔽（3,4）的温度下存在热浴（未示出）。 动态屏蔽（4）允许通过限制热通量在量热测量中有效调节通过主动屏蔽（3）的热通量。 事实上，在操作条件下，动态屏蔽作为热飞轮并保持来自主动屏蔽（3）的热通量恒定。 更详细地说，动态屏蔽（4）的存在确保了活性屏蔽（3）上的温度梯度的降低，然后降低包含样品（20）的电池（10）。 此外，通过将动态屏蔽（4）保持在与有源屏蔽（3）的适当温度差的温度下，可以比主动屏蔽（3）直接与 温泉浴。
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公开(公告)号：US09164049B2
公开(公告)日：2015-10-20
申请号：US13584382
申请日：2012-08-13
申请人： Juergen Blumm , Thomas Denner
发明人： Juergen Blumm , Thomas Denner
CPC分类号： G01N25/4806 , G01N5/04
摘要： A temperature-control device for thermoanalytical analyses, including a housing, one heating element, one protective sheath disposed in the housing, wherein the protective sheath is connectable to a gas supply. The heating element is partially arranged inside the protective sheath.
摘要翻译： 一种用于热分析分析的温度控制装置，包括壳体，一个加热元件，设置在壳体中的一个保护鞘，其中保护套可连接到气体供应。 加热元件部分地布置在保护套内。
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公开(公告)号：US20150160205A1
公开(公告)日：2015-06-11
申请号：US14626885
申请日：2015-02-19
IPC分类号： G01N33/543
CPC分类号： G01N33/54306 , B01L3/502784 , B01L7/52 , B01L2200/147 , B01L2300/0636 , B01L2300/0645 , B01L2300/0819 , B01L2300/0867 , B01L2300/0896 , B01L2300/1883 , G01K17/006 , G01N25/4806 , G01N33/54373
摘要： One aspect of the present disclosure relates to a calorimeter for detecting the presence of a target analyte in a fluid sample. The calorimeter can include a support structure, a hermetically-sealed, thermally decoupled central reaction zone associated with the support structure, at least one droplet transport region, and detection electronics. The at least one droplet transport region can be associated with the support structure and configured to merge a reagent droplet with a sample droplet including the fluid sample to form a reaction droplet in the central reaction zone. The detection electronics can be in electrical and/or thermal communication with the central reaction zone and associated with the support structure. The calorimeter can be configured to detect a heat of reaction produced by a reaction event between the target analyte and a capture reagent upon formation of the reaction droplet.
摘要翻译： 本公开的一个方面涉及一种用于检测流体样品中目标分析物的存在的量热计。 量热计可以包括支撑结构，与支撑结构相关联的气密密封的热解耦中心反应区，至少一个液滴传输区和检测电子。 所述至少一个液滴传送区域可以与所述支撑结构相关联并且被配置为将试剂液滴与包含所述流体样品的样品液滴合并以在所述中央反应区域中形成反应液滴。 检测电子设备可以与中心反应区域进行电和/或热连通并与支撑结构相关联。 热量计可以被配置为在形成反应液滴时检测由目标分析物和捕获试剂之间的反应事件产生的反应热。
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