公开(公告)号：US20180178038A1

公开(公告)日：2018-06-28

申请号：US15392999

申请日：2016-12-28

申请人： Varian Medical Systems, Inc. ,  Varian Medical Systems Particle Therapy GmbH

发明人： Vladimir ANFEROV ,  Alexander WINNEBECK

IPC分类号： A61N5/10

CPC分类号： A61N5/1077 ,  A61N5/00 ,  A61N5/1081 ,  A61N2005/1087 ,  H05H7/001 ,  H05H7/04 ,  H05H2007/002 ,  H05H2007/007 ,  H05H2007/048

摘要： A compact lightweight gantry for a proton therapy system that has a source-to-axis distance (SAD) of less than 2 m and can deliver a proton beam of superior quality. The reduced SAD leads to reduced requirements on the maximum magnetic fields that can be generated by the bend magnets in the gantry beamline. Correspondingly, lightweight bend magnets can be used. The various components in the gantry beamline are optimized to achieve a beam spot size of approximately 4 mm sigma or less through a pencil beam scanning nozzle disposed downstream of the final bending magnet. In addition, the proton therapy system is configured to operate at a maximum beam energy in the range of 220-230 MeV.

公开(公告)号：US09962560B2

公开(公告)日：2018-05-08

申请号：US14137854

申请日：2013-12-20

申请人： Mevion Medical Systems, Inc.

发明人： Gerrit Townsend Zwart ,  Mark R. Jones ,  James Cooley

IPC分类号： A61N5/10 ,  G21K1/04 ,  H05H13/02 ,  G21K1/10 ,  H05H7/00 ,  H05H7/12

CPC分类号： A61N5/1043 ,  A61N5/1042 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1077 ,  A61N5/1081 ,  A61N5/1083 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/046 ,  G21K1/10 ,  H05H13/02 ,  H05H2007/004 ,  H05H2007/007 ,  H05H2007/122

摘要： A particle therapy system includes a particle accelerator to output a particle beam; and a scanning system for the particle accelerator to scan the particle beam across at least part of an irradiation target. The scanning system is configured to scan the particle beam in two dimensions that are at an angle relative to a direction of the particle beam. A structure defines an edge. The structure is controllable to move in the two dimensions relative to the irradiation target such that at least part of the structure is between at least part of the particle beam and the irradiation target. The structure includes a material that inhibits transmission of the particle beam.

公开(公告)号：US20170157424A1

公开(公告)日：2017-06-08

申请号：US15438854

申请日：2017-02-22

申请人： Mevion Medical Systems, Inc.

发明人： Gerrit Townsend Zwart ,  Mark R. Jones

IPC分类号： A61N5/10 ,  H05H13/02 ,  G21K1/10 ,  G21K1/04

CPC分类号： A61N5/1043 ,  A61N5/1042 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1077 ,  A61N5/1081 ,  A61N5/1083 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/046 ,  G21K1/10 ,  H05H13/02 ,  H05H2007/004 ,  H05H2007/007 ,  H05H2007/122

摘要： A particle therapy system includes a particle accelerator to output a particle beam; and a scanning system for the particle accelerator to scan the particle beam across at least part of an irradiation target. The scanning system is configured to scan the particle beam in two dimensions that are at an angle relative to a direction of the particle beam. A structure defines an edge. The structure is controllable to move in the two dimensions relative to the irradiation target such that at least part of the structure is between at least part of the particle beam and the irradiation target. The structure includes a material that inhibits transmission of the particle beam.

公开(公告)号：US09314649B2

公开(公告)日：2016-04-19

申请号：US14231020

申请日：2014-03-31

申请人： Vladimir Balakin

发明人： Vladimir Balakin

IPC分类号： G21K1/08 ,  A61N5/10 ,  H01J37/141

CPC分类号： A61N5/1082 ,  A61N5/1044 ,  A61N5/1067 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1081 ,  A61N2005/1087 ,  A61N2005/1097 ,  G21K1/093 ,  G21K5/04 ,  H01J37/141 ,  H01J2237/0815 ,  H05H2007/007 ,  H05H2007/082

摘要： A fast magnet switching method and apparatus used to rapidly redirect cations, such as H+ or C6+, in a beam path, such as during or between treatment of individual volumes or voxels of a tumor of the patient, is described. Switching means include rapidly increasing or decreasing applied current to a coil about a magnet, which rapidly alters a magnetic field crossing the charged particle path and redirects a charged particle beam away from the patient, such as to a charged particle beam stop. Means to rapidly induce the current change include: (1) using a separate high voltage power supply and/or (2) opening a switch to redirect current through a resistor. In both cases, the rapid current change to the coil yields a rapid change the magnetic field and a corresponding rapid change in direction of the charged particles in the charged particle cancer therapy system.

摘要翻译： 描述了用于在诸如患者的肿瘤的个体体积或体素的处理期间或之间的波束路径中快速重定向阳离子（例如H +或C6 +）的快速磁体切换方法和装置。 切换装置包括对围绕磁体的线圈的施加电流迅速增加或减小，其迅速改变穿过带电粒子路径的磁场并将带电粒子束重新定向远离患者，诸如带电粒子束停止。 快速引起电流变化的手段包括：（1）使用单独的高压电源和/或（2）打开开关以使电流重新定向通过电阻器。 在这两种情况下，线圈的快速电流变化都会迅速改变带电粒子癌症治疗系统中带电粒子的磁场和相应的方向快速变化。

公开(公告)号：US20150273242A1

公开(公告)日：2015-10-01

申请号：US14257516

申请日：2014-04-21

申请人： Vladimir Balakin

发明人： Vladimir Balakin

IPC分类号： A61N5/10

CPC分类号： A61N5/1081 ,  A61N5/1044 ,  A61N2005/1087 ,  A61N2005/1095 ,  H05H13/04 ,  H05H2007/002 ,  H05H2007/007

摘要： A rotatable patient positioning apparatus and method of use thereof is described in combination with a rotatable magnet at a termination of a beamline arc. The rotatable patient positioning system optionally: (1) rotates a median of the person in place about a vertical axis and/or (2) rotates the entire person along a path around a vector, such as a vertical axis, where no part of the person intersects the vector. The rotatable targeting magnet rotates independently of a beamline arc at the end of the beamline arc, where the arc is after an accelerator and before the patient in a cancer therapy system. The rotatable targeting magnet directs the charged particle beam, such as vertically, using applied current to the targeting magnet while rotation of the magnet allows scanning across the tumor. The rotatable patient positioning system and targeting magnet combine to target the tumor in three-dimensions.

摘要翻译： 可旋转的患者定位装置及其使用方法与束线弧终止处的可旋转磁体一起进行描述。 可旋转的患者定位系统可选地：（1）使人的中位数围绕垂直轴旋转，和/或（2）沿着诸如垂直轴的矢量周围的路径旋转整个人，其中， 人与矢量相交。 可转动的定向磁体与束线弧的末端处的波束线弧独立地旋转，其中电弧在加速器之后并且在癌症治疗系统中的患者之前。 可旋转定向磁体通过使用施加的电流将带电粒子束（例如垂直）引导到靶向磁体，同时磁体的旋转允许跨越肿瘤扫描。 可旋转的患者定位系统和靶向磁体组合成三维靶向肿瘤。

公开(公告)号：US08787529B2

公开(公告)日：2014-07-22

申请号：US13105114

申请日：2011-05-11

申请人： William S. Graves ,  Franz X. Kaertner ,  David E. Moncton

发明人： William S. Graves ,  Franz X. Kaertner ,  David E. Moncton

IPC分类号： H01J35/02 ,  H05G2/00 ,  B82Y20/00 ,  H05H7/00

CPC分类号： H05G2/00 ,  B82Y20/00 ,  H01J35/02 ,  H01J2235/068 ,  H05G2/008 ,  H05H2007/005 ,  H05H2007/007

摘要： Coherent electronic current, which can be used to generate coherent radiation, is generated by first generating and transmitting an array of discrete electron beamlets from a nanocathode array along a longitudinal axis. The array of electron beamlets is then focused to reduce the spacing that separates the electron beamlets. The transverse-axis spacing of the electron beamlets is then transferred to the longitudinal axis via an emittance exchange beamline, creating a periodically modulated distribution of coherent electronic current. The coherent electronic current can then be directed into a stream of photons to generate coherent radiation.

摘要翻译： 通过首先沿着纵向轴线从纳米阴极阵列产生和传输离散的电子束阵列，产生可用于产生相干辐射的相干电子电流。 然后电子束的阵列被聚焦以减小分离电子束的间隔。 然后电子束的横轴间隔经由发射交换束线转移到纵轴，产生相干电子电流的周期性调制分布。 然后可以将相干电子电流引导到光子流中以产生相干辐射。

公开(公告)号：US12083362B2

公开(公告)日：2024-09-10

申请号：US17058200

申请日：2019-05-24

申请人： WIP INNOVATIONS PTY LTD

发明人： Jonathan Michael Watts

IPC分类号： A61N5/10 ,  H05H7/00 ,  H05H7/22 ,  H05H9/04

CPC分类号： A61N5/1081 ,  A61N5/1075 ,  H05H7/22 ,  H05H9/04 ,  H05H2007/007 ,  H05H2277/11

摘要： The invention relates to a drum assembly for a linear accelerator, the drum assembly comprising a drum having a front face including a front rim and a rear face including a rear rim, one or more support wheels supporting the drum, an arm extending from the front face of the drum and including a beam collimator through which a beam of radiation is emitted to form a radiation isocentre. One or more rear rim members are associated with the rear rim, the rear rim members adapted to substantially offset isocentre distortion due to unintended movement of the drum assembly. The invention also relates to variants thereto and combinations thereof.

公开(公告)号：US11825590B2

公开(公告)日：2023-11-21

申请号：US17473015

申请日：2021-09-13

申请人： Applied Materials, Inc.

发明人： William Davis Lee ,  Charles T. Carlson

IPC分类号： H05H9/04 ,  H05H7/22 ,  H05H7/00

CPC分类号： H05H9/042 ,  H05H7/001 ,  H05H7/22 ,  H05H2007/007 ,  H05H2007/222

摘要： A drift tube may include a middle portion, arranged as a hollow cylinder, and coupled to receive an RF voltage signal. The drift tube may include a first end portion, adjacent to and electrically connected to the middle portion. The middle portion and the first end portion may define a central opening to conduct an ion beam therethrough, along a direction of beam propagation. The first end portion may include a first focus assembly, and a second focus assembly, where the first focus assembly and the second focus assembly are movable with respect to one another along the direction of beam propagation, from a first configuration to a second configuration.

公开(公告)号：US20150283405A1

公开(公告)日：2015-10-08

申请号：US14246803

申请日：2014-04-07

申请人： Vladimir Balakin

发明人： Vladimir Balakin

IPC分类号： A61N5/10

CPC分类号： A61N5/1082 ,  A61N5/1044 ,  A61N5/1067 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1081 ,  A61N2005/1087 ,  A61N2005/1097 ,  G21K1/093 ,  G21K5/04 ,  H01J37/141 ,  H01J2237/0815 ,  H05H2007/007 ,  H05H2007/082

摘要： A rotatable targeting magnet apparatus and method of use thereof is described where the rotatable targeting magnet rotates independently of a beamline arc at the end of the beamline arc, where the arc is after an accelerator and before the patient in a cancer therapy system. The rotatable targeting magnet directs the charged particle beam, such as vertically, using applied current to the targeting magnet while rotation of the magnet allows scanning across the tumor. Rotation of the patient relative to the charged particle allows distribution of trailing Bragg peak energy within and/or circumferentially about the tumor.

摘要翻译： 描述了一种可旋转靶向磁铁装置及其使用方法，其中可转动的定向磁体独立于束线弧的末端处的光束弧线旋转，其中电弧在加速器之后并且在癌症治疗系统中的患者之前。 可旋转定向磁体通过使用施加的电流将带电粒子束（例如垂直）引导到靶向磁体，同时磁体的旋转允许跨越肿瘤扫描。 患者相对于带电粒子的旋转允许在肿瘤内和/或周向周围分布肿瘤的后布拉格峰能量。

公开(公告)号：US20150273240A1

公开(公告)日：2015-10-01

申请号：US14231020

申请日：2014-03-31

申请人： Vladimir Balakin

发明人： Vladimir Balakin

IPC分类号： A61N5/10 ,  H01J37/141

CPC分类号： A61N5/1082 ,  A61N5/1044 ,  A61N5/1067 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1081 ,  A61N2005/1087 ,  A61N2005/1097 ,  G21K1/093 ,  G21K5/04 ,  H01J37/141 ,  H01J2237/0815 ,  H05H2007/007 ,  H05H2007/082

摘要： A fast magnet switching method and apparatus used to rapidly redirect cations, such as H+ or C6+, in a beam path, such as during or between treatment of individual volumes or voxels of a tumor of the patient, is described. Switching means include rapidly increasing or decreasing applied current to a coil about a magnet, which rapidly alters a magnetic field crossing the charged particle path and redirects a charged particle beam away from the patient, such as to a charged particle beam stop. Means to rapidly induce the current change include: (1) using a separate high voltage power supply and/or (2) opening a switch to redirect current through a resistor. In both cases, the rapid current change to the coil yields a rapid change the magnetic field and a corresponding rapid change in direction of the charged particles in the charged particle cancer therapy system.

摘要翻译： 描述了用于在诸如患者的肿瘤的个体体积或体素的处理期间或之间的波束路径中快速重定向阳离子（例如H +或C6 +）的快速磁体切换方法和装置。 切换装置包括对围绕磁体的线圈的施加电流迅速增加或减小，其迅速改变穿过带电粒子路径的磁场并将带电粒子束重新定向远离患者，诸如带电粒子束停止。 快速引起电流变化的手段包括：（1）使用单独的高压电源和/或（2）打开开关以使电流重新定向通过电阻器。 在这两种情况下，线圈的快速电流变化都会迅速改变带电粒子癌症治疗系统中带电粒子的磁场和相应的方向快速变化。