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    Application methods to rapidly alter disease and injury states using molecular transport of B6
    1.
    发明授权
    Application methods to rapidly alter disease and injury states using molecular transport of B6 有权
    使用B6分子转运快速改变疾病和损伤状态的应用方法

    公开(公告)号：US07550488B2

    公开(公告)日：2009-06-23

    申请号：US11324693

    申请日：2005-12-30

    申请人： Alfred A Nickel

    发明人： Alfred A Nickel

    IPC分类号： A61K31/44 ,  A01N57/00 ,  A01N37/44 ,  A61K31/675 ,  A61K31/195 ,  A61K31/16

    CPC分类号： A61K31/4415 ,  A61K8/673 ,  A61K31/198 ,  A61K31/44 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/06 ,  Y10S514/86 ,  Y10S514/905 ,  Y10S514/936

    摘要： The present invention discloses methods of application employing B5/B6 vitamins in molecular transport creams or gels to deliver B6 in a high dose to bring about therapeutic ways in human or mammal tissues to reverse a disease process or injury to bring about normal function of the affected tissues. Examples of disease changes to normal include, but are not limited to strokes, cellulitis, facial acne, precancerous lesions, nerve injury like paresthesia, periorbital hematoma, pentathol general anesthesia recovery, headaches, improved sight, hypothyroidism, dental pain, dental gingivitis, insect bites, delayed hypersensitivity states, phlebitis of veins and synergism of steroid activity.

    摘要翻译： 本发明公开了在分子运输乳膏或凝胶中使用B5 / B6维生素以高剂量递送B6以在人或哺乳动物组织中产生治疗方法以逆转疾病过程或损伤以产生受影响的正常功能的方法 组织。 疾病变化正常的例子包括但不限于中风，蜂窝组织炎，面部痤疮，癌前病变，神经损伤如感觉异常，眶周血肿，戊糖全身麻醉恢复，头痛，视力改善，甲状腺功能减退，牙痛，牙龈炎，昆虫 叮咬，迟发性超敏反应状态，静脉静脉炎和类固醇活性的协同作用。

    Compositions for the treatment and prevention of cancer
    2.
    发明申请
    Compositions for the treatment and prevention of cancer 审中-公开
    用于治疗和预防癌症的组合物

    公开(公告)号：US20080170997A1

    公开(公告)日：2008-07-17

    申请号：US12077439

    申请日：2008-03-18

    申请人： Gerhard N. Schrauzer

    发明人： Gerhard N. Schrauzer

    IPC分类号： A61K9/12 ,  A61K31/095 ,  A61P35/00

    CPC分类号： A61K47/10 ,  A61K9/0014 ,  A61K9/0031 ,  A61K31/095 ,  A61K47/06 ,  A61K47/12 ,  A61K47/14 ,  A61K47/44 ,  Y10S514/858 ,  Y10S514/859 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/862 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/865 ,  Y10S514/887

    摘要： Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating organic selenium compounds in combination with inert carriers in therapeutically effective amounts of selenium compound. The selenium compounds are medium linear chain dialkyl diselenides and precursors such as alkyl selenols. Preferred compositions employ R—Se—Se—R compounds where R is from 6 to 8 carbon atoms, and most specifically di-n-hexyl diselenide. Commonly used carriers may be purified hydrocarbon fractions, oils, with or without added fat-soluble vitamins, water and emulsifying agents.

    摘要翻译： 提供组合物用于局部治疗由治疗有效量的硒化合物组成的乳液，霜剂，喷雾剂，栓剂或缓释透皮贴剂，其含有脂溶性，皮肤渗透性有机硒化合物与惰性载体的组合。 硒化合物是中等直链二烷基二硒化物和前体，例如烷基硒。 优选的组合物使用其中R为6至8个碳原子的R-Se-Se-R化合物，最特别的是二正己基二硒化物。 通常使用的载体可以是纯化的烃馏分，油，具有或不具有添加的脂溶性维生素，水和乳化剂。

    Compositions for the treatment and prevention of cancer
    3.
    发明申请
    Compositions for the treatment and prevention of cancer 失效
    用于治疗和预防癌症的组合物

    公开(公告)号：US20020197304A1

    公开(公告)日：2002-12-26

    申请号：US10179712

    申请日：2002-06-24

    发明人： Gerhard N. Schrauzer

    IPC分类号： A61K031/095 ,  A61K009/70

    CPC分类号： A61K47/10 ,  A61K9/0014 ,  A61K9/0031 ,  A61K31/095 ,  A61K47/06 ,  A61K47/12 ,  A61K47/14 ,  A61K47/44 ,  Y10S514/858 ,  Y10S514/859 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/862 ,  Y10S514/863 ,  Y10S514/864 ,  Y10S514/865 ,  Y10S514/887

    摘要： Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating organic selenium compounds in combination with inert carriers in therapeutically effective amounts of selenium compound. The selenium compounds are medium linear chain dialkyl diselenides and precursors such as alkyl selenols. Preferred compositions employ RnullSenullSenullR compounds where R is from 6 to 8 carbon atoms, and most specifically di-n-hexyl diselenide. Commonly used carriers may be purified hydrocarbon fractions, oils, with or without added fat-soluble vitamins, water and emulsifying agents.

    摘要翻译： 提供组合物用于局部治疗由治疗有效量的硒化合物组成的乳液，霜剂，喷雾剂，栓剂或缓释透皮贴剂，其含有脂溶性，皮肤渗透性有机硒化合物与惰性载体的组合。 硒化合物是中等直链二烷基二硒化物和前体，例如烷基硒。 优选的组合物使用其中R为6至8个碳原子的R-Se-Se-R化合物，最特别的是二正己基二硒化物。 通常使用的载体可以是纯化的烃馏分，油，具有或不具有添加的脂溶性维生素，水和乳化剂。

    Use of stereoisomers of calendula gylcosides for the treatment of psoriasis
    9.
    发明授权
    Use of stereoisomers of calendula gylcosides for the treatment of psoriasis 有权
    使用金盏花苷的立体异构体治疗牛皮癣

    公开(公告)号：US06313099B1

    公开(公告)日：2001-11-06

    申请号：US09355056

    申请日：2000-01-24

    申请人： Solomon Habtemariam ,  William Howard Stimson ,  Alexander Irvine Gray ,  Chaman Lal Anand ,  Peter George Waterman

    发明人： Solomon Habtemariam ,  William Howard Stimson ,  Alexander Irvine Gray ,  Chaman Lal Anand ,  Peter George Waterman

    IPC分类号： A61K3170

    CPC分类号： C07H15/20 ,  Y10S514/86 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/864

    摘要： Use of stereoisomeric glycosidic compounds of formula (I) as pharmaceutical agents against psoriasis, compounds therefor and pharmaceutical formulations thereof wherein R1 and R2 are independently selected from —H, —OH, (1) and (2) and related esters and ethers thereto; R3 is selected from —H, (3), (4), (5), (6), (7) and (8) and related esters and ethers thereto; R4 is (9); R5 is selected from the group —CH3, —CHO, —COOH, —CH2OH and related esters and ethers thereto; R6 is selected from —OH, (10), (11), (12), (13) and (14) in the preparation of a medicament for the treatment of disease involving hyperproliferation of dermis cells.

    摘要翻译： 使用式（I）的立体异构糖苷化合物作为抗银屑病的药物，其化合物及其药物组合物，其中R1和R2独立地选自-H，-OH，（1）和（2）及其相关的酯和醚; R3选自-H，（3），（4），（5），（6），（7）和（8）及其相关的酯和醚; R4是（9）; R5选自-CH 3，-CHO，-COOH，-CH 2 OH及其相关酯和醚; R 6选自-OH，（10），（11），（12），（13）和（14）在制备用于治疗涉及真皮细胞过度增殖的疾病的药物中的用途。