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    Antigenic substance inductor, vaccine precursor, vaccine, antibody, neutralizing antibody, antitoxin, idiotype antibody and/or anti-idiotype antibody which is induced by its idiotype antibody
    6.
    发明申请
    Antigenic substance inductor, vaccine precursor, vaccine, antibody, neutralizing antibody, antitoxin, idiotype antibody and/or anti-idiotype antibody which is induced by its idiotype antibody 审中-公开
    由其独特型抗体诱导的抗原物质感应器，疫苗前体，疫苗，抗体，中和抗体，抗毒素，独特型抗体和/或抗独特型抗体

    公开(公告)号：US20020009467A1

    公开(公告)日：2002-01-24

    申请号：US09881664

    申请日：2001-06-18

    发明人： Shozo Koyama ,  Satoshi Tanaka

    IPC分类号： A61K031/66 ,  A61K039/015 ,  A61K031/12

    CPC分类号： A61K39/385 ,  A61K31/122 ,  A61K2039/6012 ,  Y02A50/412 ,  Y10T436/200833

    摘要： This invention provides antigen substance inductors which produce highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin. This invention is to produce and/or manufacture highly selective and/or specific vaccine precursor, vaccine, antibody (including idiotype antibody), neutralizing antibody, antitoxin by quantum thermodynamic and chemical control of molecular functions and morphogenesis, inducing non-functional complex macromolecules which form organism and/or non-organism and which become to be substance with fundamental structure more closed to an induction of the functions, utilizing the fundamental structure of molecule which is indicated in Formula 3-a as a representative molecule. Moreover, by those produced substances, this invention is to produce and/or manufacture antimicrobial agent, antiviral agent, neutralizing antibody, antitoxin, antitumor agent, anti-protozoa agent (malaria, spirochaeta et. al), molecular discriminating agent, antibody as labeled compounds, histocompatible accelerator on tissues or organs, immuno-response accelerator or immuno-response controller, complement chain reaction accelerator. 1

    摘要翻译： 本发明提供了产生高选择性和/或特异性疫苗前体，疫苗，抗体（包括独特型抗体），中和抗体，抗毒素的抗原物质电感器。 本发明是生产和/或制造高选择性和/或特异性疫苗前体，疫苗，抗体（包括独特型抗体），中和抗体，通过量子热力学的抗毒素和分子功能和形态发生的化学控制，诱导非功能性复合大分子 形成生物体和/或非生物体，并且使用式3-a所示的分子的基本结构作为代表性分子，其具有更接近于功能诱导的基本结构的物质。 此外，本发明还涉及生产和/或生产抗微生物剂，抗病毒剂，中和抗体，抗毒素，抗肿瘤剂，抗原生动物（疟疾，螺旋虫等），分子鉴别剂，标记抗体 化合物，组织或器官上的组织相容促进剂，免疫应答加速剂或免疫应答控制剂，补体链反应促进剂。

    Anti-plasmodium compositions and methods of use
    9.
    发明申请
    Anti-plasmodium compositions and methods of use 审中-公开
    抗疟原虫组合物和使用方法

    公开(公告)号：US20020127241A1

    公开(公告)日：2002-09-12

    申请号：US09924154

    申请日：2001-08-07

    发明人： David L. Narum ,  Kim L. Sim

    IPC分类号： A61K039/002 ,  A61K039/015 ,  C12N009/24 ,  C12N015/74

    CPC分类号： C07K14/445 ,  A61K39/00 ,  Y02A50/412

    摘要： Compositions that inhibit the binding of Plasmodium falciparum to erythrocytes include a family of erythrocyte binding proteins (EBPs). The EBPs are paralogues of the P. falciparum binding protein EBA-175. The present invention includes peptides of the paralogues that prevent the binding of P. falciparum. Antibodies specific for each paralogue that also prevent the binding of P. falciparum are also included. Methods of the invention utilize the paralogues, antibodies thereof and peptide compositions for the diagnosis, prevention, and treatment of P. falciparum diseases such as malaria, as well as methods for the detection of P. falciparum in biological samples and culture media.

    摘要翻译： 抑制恶性疟原虫与红细胞结合的组合物包括红细胞结合蛋白家族（EBPs）。 EBP是恶性疟原虫结合蛋白EBA-175的旁系同源物。 本发明包括防止恶性疟原虫结合的旁系同源物的肽。 也包括也阻止恶性疟原虫结合的每个旁系同源物的抗体。 本发明的方法利用旁系同位素，其抗体和肽组合物来诊断，预防和治疗恶性疟原虫疾病如疟疾，以及生物样品和培养基中检测恶性疟原虫的方法。