D-homo-19-norsteroids
    8.
    发明授权
    D-homo-19-norsteroids 失效
    D-homo-19-降胆固醇

    公开(公告)号:US3984476A

    公开(公告)日:1976-10-05

    申请号:US621850

    申请日:1975-10-14

    IPC分类号: C07J63/00 C07C49/45

    CPC分类号: C07J63/008 Y10S514/843

    摘要: D-Homosteroids of the formula ##SPC1##Wherein R.sup.3 .alpha. is hydrogen, R.sup.3 .beta. is hydrogen, lower alkanoyloxy or aroyloxy and R.sup.3 .alpha. and R.sup.3 .beta. taken together are oxo; R.sup.13 is lower alkyl; R.sup.17a .beta. is hydrogen, lower alkanoyl, aroyl or lower alkyl; R.sup.17a .alpha. is hydrogen, lower alkyl, ethynyl, 1-propynyl, vinyl, chloroethynyl, butadiynyl or propadienyl and the dotted line in the A-ring denotes an additional carbon bond in either the 4,5- or 5(10)-position and processes for the preparation thereof are disclosed.The D-homosteroids of the present invention are useful as contraceptives and regulators of the female menstrual cycle.

    摘要翻译: 式中的D-类固醇,其中R3为氢,R3为氢,低级烷酰氧基或芳酰基,R3和R3为一起为氧代; R 13是低级烷基; R17aβ是氢,低级烷酰基,芳酰基或低级烷基; R17aa是氢,低级烷基,乙炔基,1-丙炔基,乙烯基,氯乙炔基,丁二炔基或丙二烯基,A环中的虚线表示在4,5-或5(10) - 位中的另外的碳键, 公开了其制备方法。