公开(公告)号：US12116428B2

公开(公告)日：2024-10-15

申请号：US17872050

申请日：2022-07-25

申请人： Yeda Research and Development Co. Ltd.

发明人： Jacob Klein ,  Weifeng Lin ,  Ronit Goldberg

IPC分类号： C07F9/10 ,  A61K9/00 ,  A61K9/08 ,  A61K9/127 ,  A61P19/02 ,  C08F130/02 ,  A61K47/69

CPC分类号： C08F130/02 ,  A61K9/0051 ,  A61K9/08 ,  A61K9/1273 ,  A61P19/02 ,  C07F9/106 ,  A61K9/0019 ,  A61K47/6909 ,  C08F2438/01

摘要： A polymeric compound is disclosed herein, having the general formula I:




wherein m, n, X, Y, Z and L are as defined herein. Further disclosed herein are lipid bilayers comprising at least one bilayer-forming lipid and the aforementioned polymeric compound, and liposomes comprising such a bilayer, as well as methods, uses and compositions utilizing such bilayers and/or liposomes for reducing a friction coefficient of a surface and/or for inhibiting biofilm formation.

公开(公告)号：US20230151129A1

公开(公告)日：2023-05-18

申请号：US17872050

申请日：2022-07-25

申请人： Yeda Research and Development Co. Ltd.

发明人： Jacob KLEIN ,  Weifeng LIN ,  Ronit GOLDBERG

IPC分类号： C08F130/02 ,  A61K9/127 ,  C07F9/10 ,  A61K9/08 ,  A61P19/02 ,  A61K9/00

CPC分类号： C08F130/02 ,  A61K9/08 ,  A61K9/0051 ,  A61K9/1273 ,  A61P19/02 ,  C07F9/106 ,  A61K9/0019 ,  A61K47/6909 ,  C08F2438/01

摘要： A polymeric compound is disclosed herein, having the general formula I:





wherein m, n, X, Y, Z and L are as defined herein. Further disclosed herein are lipid bilayers comprising at least one bilayer-forming lipid and the aforementioned polymeric compound, and liposomes comprising such a bilayer, as well as methods, uses and compositions utilizing such bilayers and/or liposomes for reducing a friction coefficient of a surface and/or for inhibiting biofilm formation.

公开(公告)号：US20230094929A1

公开(公告)日：2023-03-30

申请号：US17795753

申请日：2021-01-28

申请人： Fujifilm Speciality Ink Systems Limited

发明人： Sarah Canning ,  Jeremy Ward ,  Matthew Kite

IPC分类号： C09D11/38 ,  C08F112/34 ,  C08F116/36 ,  C08F122/10 ,  C08F126/02 ,  C08F116/12 ,  C08F130/02 ,  C08F126/06 ,  C08F128/06

摘要： The present invention provides an inkjet ink comprising: 10-50% by weight of one or more monomers each having a log Poctanol/water value of 5.0 or more, based on the total weight of the ink; a photoinitiator package comprising one or more photoinitiators each having a log Poctanol/water value of less than 4.0, and one or more photoinitiators selected from (I) and mixtures thereof, wherein n is a value from 1 to 10 and a+b+c is a value from 1 to 20; and wherein the one or more photoinitiators each having a log Poctanol/water value of less than 4.0 are present in the ink in an amount of 0.5-4.5% by weight, based on the total weight of the ink. The present invention also provides a method of printing the inkjet ink of the present invention.

公开(公告)号：US11101495B2

公开(公告)日：2021-08-24

申请号：US16275253

申请日：2019-02-13

申请人： Seeo, Inc. ,  Robert Bosch GmbH

发明人： Malar Azagarsamy ,  Kulandaivelu Sivanandan ,  Hany Basam Eitouni ,  Jonathan P. Mailoa ,  Georgy Samsonidze ,  Boris Kozinsky ,  Mordechai Kornbluth

IPC分类号： H01M10/056 ,  H01M10/0525 ,  H01M10/0565 ,  C08F130/02

摘要： New phosphorous-based polyesters have been synthesized. When these polymers are combined with electrolyte salts, such polymer electrolytes have shown excellent electrochemical oxidation stability in lithium battery cells. Their stability along with their excellent ionic transport properties make them especially suitable as electrolytes in high energy density lithium battery cells.

公开(公告)号：US20210147583A1

公开(公告)日：2021-05-20

申请号：US17256387

申请日：2018-12-12

申请人： South China University of Technology

发明人： Li Ren ,  Sa Liu ,  Renjian Xie

IPC分类号： C08B37/08 ,  C08G81/02 ,  C08F130/02 ,  A61P19/02 ,  A61L31/04 ,  A61K31/728

摘要： Disclosed are a hyaluronic acid-based zwitterionic polymer brush, a preparation method thereof, and the use thereof. The structure of the zwitterionic polymer brush is represented by formula (I), wherein n is an integer from 60-150, x is an integer from 589-686, and y is an integer from 125-230. The above-mentioned zwitterionic polymer brush can delay the pathological progress of osteoarthritis, promote cartilage regeneration, and even treat osteoarthritis and improve conditions such as the generation of abraded fragments of implants such as joints and related diseases triggered thereby, and can be combined with cartilage repairing materials to improve the frictional mechanical properties thereof for achieving better repair results. Moreover, the above-mentioned zwitterionic polymer brush can selectively bind to proteins in cartilage and has an excellent lubricating effect. The present invention has the advantages of simple method, convenient operation, easy purification, high yield, and the like.

公开(公告)号：US20200332033A1

公开(公告)日：2020-10-22

申请号：US16919138

申请日：2020-07-02

申请人： Yeda Research and Development Co. Ltd.

发明人： Jacob KLEIN ,  Weifeng LIN ,  Ronit GOLDBERG

IPC分类号： C08F130/02 ,  A61K9/127 ,  C07F9/10 ,  A61K9/08 ,  A61P19/02 ,  A61K9/00

摘要： A polymeric compound is disclosed herein, having the general formula I: wherein m, n, X, Y, Z and L are as defined herein. Further disclosed herein are lipid bilayers comprising at least one bilayer-forming lipid and the aforementioned polymeric compound, and liposomes comprising such a bilayer, as well as methods, uses and compositions utilizing such bilayers and/or liposomes for reducing a friction coefficient of a surface and/or for inhibiting biofilm formation.

公开(公告)号：US10760000B2

公开(公告)日：2020-09-01

申请号：US16111683

申请日：2018-08-24

申请人： International Business Machines Corporation

发明人： Scott B. King ,  Brandon M. Kobilka ,  Joseph Kuczynski ,  Jason T. Wertz

IPC分类号： C07F9/40 ,  C09K21/12 ,  C08K5/5333 ,  C09K21/14 ,  C07F9/12 ,  C08F230/02 ,  C07F9/145 ,  C08K5/5337 ,  C08F130/02 ,  C08K5/5373 ,  C08K5/5353 ,  C08K5/5357 ,  C08F30/02 ,  C08G59/30 ,  C08G79/02 ,  C08G59/04 ,  C08G73/02 ,  C08G69/02 ,  C08G59/02 ,  C08G63/08 ,  C07F9/14 ,  C07F9/655 ,  C08K5/52 ,  C08G59/32 ,  C08G79/06 ,  C08G69/26 ,  C08G63/13 ,  C08G63/692 ,  C08G63/12

摘要： A process of forming a resveratrol-based flame retardant small molecule with a phosphonate/phosphinate molecule that includes a chloride group and a terminal functional group.

公开(公告)号：US10584282B2

公开(公告)日：2020-03-10

申请号：US15539524

申请日：2015-12-24

申请人： KURARAY CO., LTD.

发明人： Masahiko Ota ,  Yasutaka Inubushi ,  Ryoichi Sasaki ,  Yasushi Morihara ,  Masakazu Nakaya

IPC分类号： B32B9/00 ,  B82Y20/00 ,  B82Y40/00 ,  C09K11/02 ,  C09D129/04 ,  H01L33/62 ,  C09K11/70 ,  C09D143/02 ,  C08F130/02 ,  C09D7/40 ,  C09D5/22 ,  C09D171/02 ,  C09K11/08 ,  H01L33/50 ,  B82Y30/00 ,  H01L33/48 ,  H01L33/58

摘要： The present invention relates to a fluorescent quantum dot-containing electronic device including a protective sheet. The protective sheet includes a multilayer structure (W) including a base (X) and a layer (Y) stacked on the base (X), the layer (Y) contains a reaction product (D) of an aluminum-containing compound (A) and a phosphorus compound (B), and the reaction product (D) has an average particle diameter of 5 to 50 nm.

公开(公告)号：US10251982B2

公开(公告)日：2019-04-09

申请号：US15429835

申请日：2017-02-10

申请人： BioInteractions Ltd.

发明人： Fanny Burrows ,  John E. Mckendrick ,  Alan Rhodes ,  Simon J. Onis ,  Shivpal S. Sandhu

IPC分类号： C08F18/22 ,  A61L33/00 ,  C08F222/02 ,  A61L27/34 ,  A61L31/10 ,  C07F9/10 ,  C07F9/6574 ,  A61L29/08 ,  A61L29/14 ,  A61L29/16 ,  A61L31/14 ,  A61L31/16 ,  A61L33/06 ,  C08F230/02 ,  C07F9/09 ,  C08F220/18 ,  C08F220/28 ,  C09D133/14 ,  G02B1/04 ,  C07F9/40 ,  C07F9/06 ,  C07F9/08 ,  C07F9/32 ,  C07F9/36 ,  C08F130/02 ,  C08F122/02 ,  C08F30/02 ,  C08F8/40 ,  C08F8/30 ,  C08F16/14 ,  C08F216/14 ,  C08F116/14

摘要： New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers exhibiting improved biocompatibility, haemocompatibility, hydrophilicity non-thrombogenicity, anti-bacterial ability, and mechanical strength, as well as suitability as a drug delivery platform.

公开(公告)号：US20190002609A1

公开(公告)日：2019-01-03

申请号：US16064498

申请日：2016-12-22

申请人： Yeda Research and Development Co. Ltd.

发明人： Jacob KLEIN ,  Weifeng LIN ,  Ronit GOLDBERG

IPC分类号： C08F130/02 ,  A61K9/127 ,  A61K9/00 ,  C07F9/10

CPC分类号： C08F130/02 ,  A61K9/0019 ,  A61K9/0051 ,  A61K9/08 ,  A61K9/1273 ,  A61K47/6909 ,  A61P19/02 ,  C07F9/106 ,  C08F2438/01

摘要： A polymeric compound is disclosed herein, having the general formula I: wherein m, n, X, Y, Z and L are as defined herein. Further disclosed herein are lipid bilayers comprising at least one bilayer-forming lipid and the aforementioned polymeric compound, and liposomes comprising such a bilayer, as well as methods, uses and compositions utilizing such bilayers and/or liposomes for reducing a friction coefficient of a surface and/or for inhibiting biofilm formation.