公开(公告)号：US08441633B2

公开(公告)日：2013-05-14

申请号：US12915921

申请日：2010-10-29

申请人： Thai V. Truong ,  John M. Choi ,  Scott E. Fraser ,  Willy Supatto ,  David S. Koos

发明人： Thai V. Truong ,  John M. Choi ,  Scott E. Fraser ,  Willy Supatto ,  David S. Koos

IPC分类号： G01J3/40 ,  G01J3/30 ,  G01J1/58 ,  F21V9/16 ,  G01T1/10 ,  G21H3/02 ,  G21K5/00 ,  H01J65/06 ,  H01J65/08

CPC分类号： G02B21/16 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/655 ,  G02B21/002 ,  G02B21/367

摘要： An apparatus for and method of performing multi-photon light sheet microscopy (MP-LISH), combining multi-photon excited fluorescence with the orthogonal illumination of light sheet microscopy are provided. With live imaging of whole Drosophila and zebrafish embryos, the high performance of MP-LISH compared to current state-of-the-art imaging techniques in maintaining good signal and high spatial resolution deep inside biological tissues (two times deeper than one-photon light sheet microscopy), in acquisition speed (more than one order of magnitude faster than conventional two-photon laser scanning microscopy), and in low phototoxicity are demonstrated. The inherent multi-modality of this new imaging technique is also demonstrated second harmonic generation light sheet microscopy to detect collagen in mouse tail tissue. Together, these properties create the potential for a wide range of applications for MP-LISH in 4D imaging of live biological systems.

摘要翻译： 提供了一种多光子激光荧光与光谱显微镜正交照明相结合的多光子光谱显微镜（MP-LISH）的设备和方法。 通过对整个果蝇和斑马鱼胚胎的实时成像，MP-LISH的高性能与目前最先进的成像技术相比，保持生物组织内部的良好信号和高空间分辨率（比单光子光更深两倍） 片状显微镜），在采集速度（比常规双光子激光扫描显微镜快超过一个数量级），并且具有低的光毒性。 这种新的成像技术的固有多模态也被证明了二次谐波发生光片显微镜检测小鼠尾部组织中的胶原蛋白。 共同的，这些属性为MP-LISH在活体生物系统4D成像中的应用提供了广泛的应用。

公开(公告)号：US08000574B2

公开(公告)日：2011-08-16

申请号：US10586527

申请日：2005-01-24

申请人： Scott Charles Buchter ,  Hanne Elisabeth Ludvigsen ,  Matti Kaivola

发明人： Scott Charles Buchter ,  Hanne Elisabeth Ludvigsen ,  Matti Kaivola

IPC分类号： G02B6/02 ,  H01J65/08

CPC分类号： G02F1/365 ,  G02F2001/3528

摘要： A method of generating supercontinuum optical radiation, the method comprising: (a) providing an optical waveguide (22), said optical waveguide exhibiting a dispersion characteristic of guided optical radiation, said dispersion characteristic comprising: (i) a first dispersion parameter (β21) at a first wavelength (λ1), (ii) a second dispersion parameter (β22) at a second shorter wavelengths (λ2), and (iii) a zero-dispersion parameter at a wavelength in between said first and said second shorter wavelengths; said optical waveguide further comprising at least one entrance for receiving optical radiation, and at least one exit for emitting guided optical radiation; (b) applying at least two laser radiation of said first (25) wavelength, (λ1) at a first power (P1) and applying laser radiation of said second (26) shorter wavelength (λ2) at a second power (P2) into said optical waveguide, said laser radiations at least partially overlapping between said at least one entrance and said at least one exit of said optical waveguide; and (c) phase-matching said applied laser radiations by adjusting said first and second powers; a supercontinuum optical radiation source; and use thereof.

摘要翻译： 一种产生超连续谱光辐射的方法，所述方法包括：（a）提供光波导（22），所述光波导呈现引导光辐射的色散特性，所述色散特征包括：（i）第一色散参数（＆bgr; （λ1）的第二色散参数（＆bgr; 22），以及（iii）在所述第一和第二波长处的波长处的零色散参数（λ2） 较短波长; 所述光波导还包括用于接收光辐射的至少一个入口和用于发射引导光辐射的至少一个出射口; （b）以第一功率（P1）施加所述第一波长（25）的至少两个激光辐射（λ1），并以第二功率（P2）将所述第二（26）短波长（λ2）的激光辐射施加到第二功率 所述光波导，所述激光辐射在所述光波导的所述至少一个入口和所述至少一个出口之间至少部分重叠; 以及（c）通过调整所述第一和第二功率来相位匹配所述施加的激光辐射; 超连续光学辐射源; 及其用途。

公开(公告)号：US07202953B1

公开(公告)日：2007-04-10

申请号：US09868845

申请日：1999-12-21

申请人： Juergen Rolf Mueller ,  Karsten Henco ,  Rodney Turner ,  Peter Axhausen ,  Rolf Guenther

发明人： Juergen Rolf Mueller ,  Karsten Henco ,  Rodney Turner ,  Peter Axhausen ,  Rolf Guenther

IPC分类号： G01N21/55 ,  G01N21/00 ,  G01J3/44 ,  G01J3/30 ,  G01J4/00 ,  G01J1/58 ,  G01B11/14 ,  G02B7/04 ,  G02B27/40 ,  G02B27/64 ,  F21V9/16 ,  G01T1/10 ,  G21H3/02 ,  G21K5/00 ,  H01J65/06 ,  H01J65/08

CPC分类号： G01J3/02 ,  G01J3/0237 ,  G01N21/6408 ,  G01N21/6445 ,  G01N21/6458 ,  G01N21/65 ,  G01N2021/6439 ,  G02B21/006 ,  G02B21/0068 ,  G02B21/0076 ,  G02B21/008

摘要： The invention relates to a method for optically detecting at least one entity which is arranged on a substrate. The at least one entity is scanned with a measuring volume using at least one radiation source and a confocal optic. During a scanning process an auxiliary focus is generated by means of at least one second radiation source and a second optic. Radiation generated by the first radiation source is collimated by a first optic and radiation generated by the second radiation source is collimated by a second optic. A retroreflection from the auxiliary focus is detected by at least one detector and is used to measuring the position of an interface and, thus, for indirectly positioning the measuring volume. The position of the auxiliary focus relative to the measuring volume is adjustable in a defined manner.

摘要翻译： 本发明涉及一种用于光学检测布置在基底上的至少一个实体的方法。 至少一个实体使用至少一个辐射源和共焦光学元件用测量体积扫描。 在扫描过程中，通过至少一个第二辐射源和第二光学器件产生辅助焦点。 由第一辐射源产生的辐射由第一光学器准直，并且由第二光源产生的辐射由第二光学器件准直。 通过至少一个检测器检测来自辅助焦点的回射，并且用于测量界面的位置，并且因此用于间接地定位测量体积。 辅助焦点相对于测量体积的位置可以以一种定义的方式进行调节。

公开(公告)号：US4935632A

公开(公告)日：1990-06-19

申请号：US271436

申请日：1988-11-15

申请人： Douglas Hart

发明人： Douglas Hart

IPC分类号： F21K99/00 ,  G21H3/02 ,  H01J65/08

CPC分类号： F21K99/00 ,  G21H3/02 ,  H01J65/08

摘要： A light assembly comprises a self-luminescent light source, a wave guide and output optics. The self-luminescent light source takes the form of a luminescent concentrator which is activated by beta radiation from tritium which is immobilized in a matrix in which a luminescent material is distributed.

摘要翻译： 灯组件包括自发光光源，波导和输出光学器件。 自发光光源采用发光浓缩器的形式，其由来自氚的β辐射激活，其固定在分布有发光材料的基质中。

公开(公告)号：US4827176A

公开(公告)日：1989-05-02

申请号：US135077

申请日：1987-12-18

申请人： Shinji Inukai ,  Kazuo Honda ,  Akihiro Kamiya

发明人： Shinji Inukai ,  Kazuo Honda ,  Akihiro Kamiya

IPC分类号： H01J61/54 ,  H01J61/18 ,  H01J17/32 ,  H01J65/08

CPC分类号： H01J61/548

摘要： A metal vapor discharge lamp. The metal vapor discharge lamp includes an enclosed discharge tube having a pair of main electrodes mounted at spaced apart locations therein, the discharge tube including a fill of at least a metal vapor and a starting gas, a radiation source including radioactively impregnated ceramic material having a vitrified radioactive outer protection portion and an outer bulb for enclosing the discharge tube and a circuit for electrically generating an arc between the main electrodes.

摘要翻译： 金属蒸汽放电灯。 金属蒸汽放电灯包括封闭的放电管，其具有安装在其间隔开的位置的一对主电极，放电管包括至少金属蒸气和起始气体的填充物，辐射源包括放射性浸渍的陶瓷材料，其具有 玻璃化放射性外保护部分和用于封闭放电管的外灯泡和用于在主电极之间产生电弧的电路。

公开(公告)号：US4445067A

公开(公告)日：1984-04-24

申请号：US265675

申请日：1981-05-20

申请人： Akihiro Inoue ,  Tadao Kanoh ,  Taketo Kamei ,  Akihiro Kamiya ,  Toshihiko Ishigami ,  Akira Kohno ,  Hiroki Sasaki

发明人： Akihiro Inoue ,  Tadao Kanoh ,  Taketo Kamei ,  Akihiro Kamiya ,  Toshihiko Ishigami ,  Akira Kohno ,  Hiroki Sasaki

IPC分类号： H01J7/40 ,  H01J61/54 ,  H01J61/82 ,  H01J65/08

CPC分类号： H01J7/40 ,  H01J61/548 ,  H01J61/82

摘要： A high pressure metal vapor discharge lamp including an arc tube having opposed ends at which are provided respective main electrodes and a fill including mercury and a starting gas, a radioactive source material including a radioactive substance having a half-life less than 1.times.10.sup.4 years sealed in the arc tube, an outer tube enclosing the arc tube and a circuit for starting the arc tube.

摘要翻译： 一种高压金属蒸汽放电灯，包括具有相对端的电弧管，各电主管设有相应的主电极和包括汞和起始气体的填充物，包括半衰期小于1×104年的放射性物质的放射源材料密封在 电弧管，封闭电弧管的外管和用于启动电弧管的电路。

公开(公告)号：US2155449A

公开(公告)日：1939-04-25

申请号：US23671538

申请日：1938-10-24

申请人： SEAMAN ELLSWORTH F

发明人： SEAMAN ELLSWORTH F

IPC分类号： F21V9/16 ,  G09F13/14 ,  G09F13/16 ,  H01J65/08

CPC分类号： G09F13/16 ,  F21V9/16 ,  G09F13/14 ,  H01J65/08

公开(公告)号：US2028241A

公开(公告)日：1936-01-21

申请号：US73070534

申请日：1934-06-15

申请人： UNITED STATES RADIUM CORP

发明人： PAUL JOHN E

IPC分类号： F21V9/16 ,  H01J65/08

CPC分类号： F21V9/16 ,  H01J65/08

公开(公告)号：US09921161B1

公开(公告)日：2018-03-20

申请号：US14991016

申请日：2016-01-08

申请人： Daniel Feldkhun

发明人： Daniel Feldkhun

IPC分类号： H01J65/08 ,  G01N21/64 ,  G02B21/16 ,  G02B21/36

CPC分类号： G01N21/6458 ,  G02B21/0032 ,  G02B21/14 ,  G02B21/16 ,  G02B21/365 ,  G02B27/58

摘要： Methods and systems are provided for estimating locations of sub-wavelength-sized emitters, which may be sparsely arrayed among inactive emitters, in one or more dimensions to synthesize a super-resolved image. The emitter emits light in response to structured illumination, which may be acousto-optically generated. The structured illumination is translated, and a detector, such as a camera pixel, senses the emitted linear or nonlinear response, producing a periodic signal. A processor computes a phase of the signal using phase shifting interferometry and uses it to estimate the emitter location with resolution finer than a quarter of the illumination wavelength. Modulation depth and/or amplitude of the signal may be used to estimate emitter size and/or evaluate location fidelity. Optical sectioning or extended depth of field may be provided by controlling spatial coherence of the illumination. Encoding and decoding emitter locations with non-periodic patterns is also described.

公开(公告)号：US09187034B2

公开(公告)日：2015-11-17

申请号：US13833396

申请日：2013-03-15

申请人： International Automotive Components Group North America, Inc.

发明人： Sassan Tarahomi ,  Zachary Seguin

IPC分类号： F21V9/16 ,  G01J1/58 ,  G01T1/10 ,  G21H3/02 ,  G21K5/00 ,  H01J65/06 ,  H01J65/08 ,  B60Q3/00 ,  B60Q3/02 ,  B60R13/02 ,  F21K2/00 ,  C09K11/02

CPC分类号： C09K11/025 ,  B60Q3/68 ,  B60Q3/745 ,  B60R13/02 ,  B60R2013/0287 ,  C09K11/08 ,  F21K2/00

摘要： A component of a motor vehicle comprising a photoluminescent interior member formed of a plastic composition, wherein the plastic composition comprises at least one polymer and a plurality of additives comprising at least one photoluminescent material and at least a first ultraviolet protector, wherein the at least one photoluminescent material absorbs electromagnetic radiation in a first ultraviolet range of an electromagnetic spectrum, and thereafter emits electromagnetic radiation in a visible radiation range of the electromagnetic spectrum, and wherein the first ultraviolet protector is an ultraviolet absorber, wherein the ultraviolet absorber absorbs electromagnetic radiation in a second ultraviolet range of the electromagnetic spectrum and does not absorb electromagnetic radiation in the first ultraviolet range of the electromagnetic spectrum.

摘要翻译： 一种机动车辆的组件，包括由塑料组合物形成的光致发光内部构件，其中塑料组合物包含至少一种聚合物和多种添加剂，其包含至少一种光致发光材料和至少第一紫外线保护剂，其中至少一种 光致发光材料在电磁光谱的第一紫外线范围内吸收电磁辐射，然后在电磁光谱的可见光辐射范围内发射电磁辐射，其中第一紫外线保护器是紫外线吸收剂，其中紫外线吸收剂吸收电磁辐射 电磁波谱的第二紫外线范围，并且不吸收电磁波谱的第一紫外线范围内的电磁辐射。