公开(公告)号：US12128120B2

公开(公告)日：2024-10-29

申请号：US18217568

申请日：2023-07-02

申请人： Next Science IP Holdings Pty Ltd

发明人： Matthew F. Myntti

IPC分类号： A61K8/49 ,  A01N25/02 ,  A01N25/08 ,  A01N25/30 ,  A01N37/36 ,  A01N41/04 ,  A01N59/00 ,  A01N59/26 ,  A01N61/00 ,  A61K8/19 ,  A61K8/34 ,  A61K8/365 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/55 ,  A61K8/60 ,  A61K8/86 ,  A61K9/00 ,  A61K9/06 ,  A61K31/14 ,  A61K31/19 ,  A61K31/194 ,  A61K33/00 ,  A61K33/02 ,  A61K33/04 ,  A61K33/20 ,  A61K33/24 ,  A61K33/32 ,  A61K33/42 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/34 ,  A61L26/00 ,  A61P17/02 ,  A61P31/04 ,  A61Q11/00 ,  A61Q17/00 ,  A61K9/08

CPC分类号： A61K8/498 ,  A01N25/02 ,  A01N25/08 ,  A01N25/30 ,  A01N37/36 ,  A01N41/04 ,  A01N59/00 ,  A01N59/26 ,  A01N61/00 ,  A61K8/19 ,  A61K8/34 ,  A61K8/347 ,  A61K8/365 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/416 ,  A61K8/44 ,  A61K8/463 ,  A61K8/466 ,  A61K8/4926 ,  A61K8/4973 ,  A61K8/55 ,  A61K8/602 ,  A61K8/86 ,  A61K9/0014 ,  A61K9/0063 ,  A61K9/06 ,  A61K31/14 ,  A61K31/19 ,  A61K31/194 ,  A61K33/00 ,  A61K33/02 ,  A61K33/04 ,  A61K33/20 ,  A61K33/24 ,  A61K33/32 ,  A61K33/42 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/34 ,  A61L26/0066 ,  A61P17/02 ,  A61P31/04 ,  A61Q11/00 ,  A61Q17/005 ,  A61K9/08 ,  A61L2300/404 ,  A01N37/36 ,  A01N59/26 ,  A01N2300/00 ,  A01N25/02 ,  A01N25/30 ,  A01N59/00 ,  A01N61/00 ,  A01N25/08 ,  A01N25/30 ,  A01N59/00 ,  A01N61/00

摘要： An aqueous composition with a higher-than-neutral pH includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. This composition, as well as an acidic counterpart and solid materials, can be used in a variety of applications such as wound care, oral care, medical equipment reprocessing, healthcare acquired infection and implant treatment.

公开(公告)号：US12128116B2

公开(公告)日：2024-10-29

申请号：US18174082

申请日：2023-02-24

申请人： The Procter & Gamble Company

发明人： Mark Anthony Brown ,  Gemma Zoe Braganza ,  Junichi Yokogi ,  William Randal Belcher ,  Linda Sue Reed ,  Jorge Max Sunkel

IPC分类号： A61K8/00 ,  A61K8/02 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K8/46 ,  A61K8/60 ,  A61Q5/02 ,  A61Q19/10

CPC分类号： A61K8/0241 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K8/342 ,  A61K8/361 ,  A61K8/375 ,  A61K8/416 ,  A61K8/42 ,  A61K8/44 ,  A61K8/463 ,  A61K8/602 ,  A61Q5/02 ,  A61Q19/10 ,  A61K2800/31 ,  A61K2800/41

摘要： A cleansing composition comprising a detersive surfactant; an aqueous carrier; from about 0.5% to about 30% by weight of the cleansing composition of discrete particles comprising anhydrous particles and an aqueous phase, and wherein said anhydrous particles comprise: one or more fatty amphiphile selected from the group consisting of fatty alcohol, fatty ester, fatty acid, fatty amide and mixtures thereof; of one or more secondary surfactants selected from the group consisting of anionic, nonionic, zwitterionic, cationic or mixtures thereof. Wherein the discrete particle of the cleansing composition has a size from about 500 microns to about 7000 microns, and wherein the cleansing composition has a % transmittance of about 75% or higher.

公开(公告)号：US12121601B2

公开(公告)日：2024-10-22

申请号：US17614548

申请日：2021-02-04

申请人： SHANGHAI JIAO TONG UNIVERSITY

发明人： Guangyin Yuan ,  Wenjiang Ding ,  Yueling Li ,  Li Shen ,  Jianxiong Yuan

IPC分类号： A61K8/19 ,  A61K8/25 ,  A61K8/34 ,  A61K8/46 ,  A61K8/73 ,  A61K8/81 ,  A61K8/9789 ,  A61K33/06 ,  A61P1/02 ,  A61Q11/00

CPC分类号： A61K8/19 ,  A61K8/25 ,  A61K8/345 ,  A61K8/463 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61K8/9789 ,  A61K33/06 ,  A61P1/02 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/75

摘要： The-use of magnesium hydride in the preparation of a composition for preventing and treating chronic periodontitis, and a magnesium hydride toothpaste are provided. In the composition or the magnesium hydride toothpaste, magnesium hydride has a weight percentage of 1% to 3%. The toothpaste has the functions of disinfection, anti-inflammation, anti-oxidation, removing tooth stains, improving bad breath, alleviating gingival swelling, bleeding, and recession, and improving periodontitis symptoms. An appropriate amount of magnesium hydride fine particles is added in toothpaste, and the magnesium hydride particles can be hydrolyzed into hydrogen and magnesium ions with anti-inflammatory effects, which can also inhibit alveolar bone resorption. The magnesium hydride-containing composition is safe in use, and can effectively prevent the occurrence and development of periodontal diseases after long-term use.

公开(公告)号：US20240325259A1

公开(公告)日：2024-10-03

申请号：US18292982

申请日：2022-07-19

申请人： V. MANE FILS

发明人： Elsa RAYNAUD ,  Agnes MURATORE

IPC分类号： A61K8/06 ,  A61K8/34 ,  A61K8/41 ,  A61K8/46 ,  A61K8/92 ,  A61Q13/00

CPC分类号： A61K8/068 ,  A61K8/345 ,  A61K8/416 ,  A61K8/466 ,  A61K8/922 ,  A61Q13/00 ,  A61K2800/262 ,  A61K2800/412

摘要： A transparent, aqueous perfume micro-emulsion composition is provided that includes a fragrance material, a solvo-surfactant, an ionic surfactant, optionally a non-ionic surfactant, and water. The solvo-surfactant comprises at least one monoalkyl glycerol ether having a general formula of R—O—CH2—CH(OH)—CH2OH, wherein R is selected from the group consisting of C8 to C12 unbranched alkyls and C6 to C7 unbranched terminal alkenyls. The aqueous perfume microemulsions are stable and may be used in their concentrated form or diluted with water depending on the end use application.

公开(公告)号：US12102708B2

公开(公告)日：2024-10-01

申请号：US18600658

申请日：2024-03-09

申请人： Imam Abdulrahman Bin Faisal University

发明人： Abdul Samad Khan

IPC分类号： A61K8/9789 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/34 ,  A61K8/368 ,  A61K8/46 ,  A61K8/73 ,  A61Q11/00

CPC分类号： A61K8/9789 ,  A61K8/25 ,  A61K8/27 ,  A61K8/29 ,  A61K8/345 ,  A61K8/368 ,  A61K8/463 ,  A61K8/731 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/524

摘要： A tooth paste composition comprising black cumin oil (Nigella sativa) and fluoride-doped bioactive glass, zinc oxide, and/or titanium oxide is disclosed.

公开(公告)号：US20240285485A1

公开(公告)日：2024-08-29

申请号：US18586718

申请日：2024-02-26

申请人： TOSHIKI PIGMENT CO., LTD.

发明人： Kazuyoshi TSUBATA

IPC分类号： A61K8/06 ,  A61K8/31 ,  A61K8/365 ,  A61K8/37 ,  A61K8/46 ,  A61K8/92 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10

CPC分类号： A61K8/064 ,  A61K8/31 ,  A61K8/365 ,  A61K8/37 ,  A61K8/46 ,  A61K8/922 ,  A61K8/927 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61K2800/34

摘要： Provided is a water-in-oil type solid emulsified cosmetic preparation with good feelings from use. The water-in-oil type solid emulsified cosmetic preparation, contains, and being substantially free of silicone compounds, a compound which is pasty at 25° C.; a compound selected from PEG-30 dipolyhydroxystearate, PEG-5 hydrogenated castor oil, PEG-10 hydrogenated castor oil, PEG-20 hydrogenated castor oil, PEG-30 hydrogenated castor oil, PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and a combination of these; a solid oil component having a melting point of 65° C. or more; a low-viscosity liquid oil component having a viscosity of 40 mPa·s or less at 25° C.; and water.

公开(公告)号：US12053536B2

公开(公告)日：2024-08-06

申请号：US17713611

申请日：2022-04-05

申请人： Colgate-Palmolive Company

发明人： Xiang Chen ,  Suman Chopra

IPC分类号： A61K8/22 ,  A61K8/36 ,  A61K8/46 ,  A61K8/60 ,  A61K8/81 ,  A61K8/86 ,  A61Q11/00

CPC分类号： A61K8/22 ,  A61K8/361 ,  A61K8/463 ,  A61K8/60 ,  A61K8/8176 ,  A61K8/86 ,  A61Q11/00 ,  A61K2800/30 ,  A61K2800/31 ,  A61K2800/882

摘要： Disclosed herein are oral care compositions comprising an oral care composition comprising a peroxide whitening complex present in an amount to provide from about 3.0% to about 8% of hydrogen peroxide by weight of the composition; a block copolymer of ethylene oxide and propylene oxide in an amount from about 0.01% to about 8% by weight of the composition; a stearate in an amount from about 0.3% to about 5% by weight of the composition; and a humectant in an amount from about 60% to about 90% by weight of the composition. Methods of making and using the oral care compositions are also provided.

公开(公告)号：US20240252406A1

公开(公告)日：2024-08-01

申请号：US18561318

申请日：2022-05-18

申请人： Conopco, Inc., d/b/a UNILEVER

发明人： Hasiba BEKTO ,  Lei HUANG

IPC分类号： A61K8/34 ,  A61K8/06 ,  A61K8/37 ,  A61K8/46 ,  A61K8/49 ,  A61K8/81 ,  A61Q19/08

CPC分类号： A61K8/347 ,  A61K8/06 ,  A61K8/37 ,  A61K8/375 ,  A61K8/46 ,  A61K8/4926 ,  A61K8/8147 ,  A61Q19/08

摘要： A cosmetic composition comprises resorcinol, functionalized heteroaromatic compound, and a retinoic acid precursor. An effective way to improve the color stability of compositions comprising such skin benefit agents is desired. It has been found that alkylresorcinol, functionalized heteroaromatic compound, and retinoic acid precursor in combination with antioxidant, compatible oil and emulsifying polymer provide for improved color stability of the composition. The inventive composition thus relates to a composition comprising a synergistic combination of emulsifying polymer with alkylresorcinols, functionalized heteroaromatic compounds CA and retinoidsin combination with antioxidant and compatible oil.

公开(公告)号：US12048854B2

公开(公告)日：2024-07-30

申请号：US18148724

申请日：2022-12-30

申请人： Colgate-Palmolive Company

发明人： Suman Chopra ,  Dennis Ontumi ,  Prakasarao Mandadi ,  Venda Porter Maloney

IPC分类号： A61Q11/00 ,  A61K8/02 ,  A61K8/22 ,  A61K8/24 ,  A61K8/34 ,  A61K8/46 ,  A61K8/81 ,  A61K8/86 ,  A61K8/90

CPC分类号： A61Q11/00 ,  A61K8/0216 ,  A61K8/22 ,  A61K8/24 ,  A61K8/345 ,  A61K8/463 ,  A61K8/8176 ,  A61K8/8182 ,  A61K8/86 ,  A61K8/90 ,  A61K2800/28 ,  A61K2800/31 ,  A61K2800/52 ,  A61K2800/57 ,  A61K2800/87

摘要： Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with particular co-polymers as additional excipients; including some embodiments which further comprise a calcium abrasive.

公开(公告)号：US20240238175A1

公开(公告)日：2024-07-18

申请号：US18614050

申请日：2024-03-22

申请人： Colgate-Palmolive Company

发明人： Guisheng PAN ,  Suman CHOPRA

IPC分类号： A61K8/25 ,  A61K8/02 ,  A61K8/19 ,  A61K8/46 ,  A61Q11/00 ,  C01B33/18 ,  C03C15/00 ,  C03C17/22 ,  C03C17/23 ,  C09C1/30 ,  C09K3/14

CPC分类号： A61K8/25 ,  A61K8/022 ,  A61K8/0241 ,  A61K8/0245 ,  A61K8/0258 ,  A61K8/19 ,  A61K8/466 ,  A61Q11/00 ,  C01B33/18 ,  C03C15/00 ,  C03C17/22 ,  C03C17/23 ,  C09C1/3054 ,  C09K3/1436 ,  C09K3/1445 ,  A61K2800/28 ,  A61K2800/621 ,  A61K2800/651 ,  A61K2800/92 ,  C01P2004/61 ,  C01P2004/84

摘要： The present invention relates to core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core is etched with metal silicate, the core shell silica particles prepared by: i) admixing an amount of silica particles in water with an amount of a base, wherein the base comprises a monovalent metal ion, to produce core shell silica particles, each core shell silica particle comprising a silica core, and a surface of the silica core etched with a silicate of the monovalent metal ion; and ii) reacting the core shell silica particles formed in step i) with a metal salt comprising a second metal ion, to form core shell silica particles comprising silicate of the second metal ion on the surface of the silica core.