公开(公告)号：US11596662B2

公开(公告)日：2023-03-07

申请号：US17239042

申请日：2021-04-23

申请人： LABORATOIRES EXPANSCIENCE

发明人： Sophie Leclere-Bienfait ,  Stéphanie Bredif

IPC分类号： A61K36/185 ,  A61K8/49 ,  A61Q17/04 ,  A61Q19/08 ,  A61Q19/06 ,  A61Q17/00 ,  A61K8/9789 ,  A61P17/16 ,  A61P29/00 ,  A61K8/368 ,  A61K31/192 ,  A61K31/353 ,  A61Q19/00

摘要： The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof.

公开(公告)号：US20230067277A1

公开(公告)日：2023-03-02

申请号：US17793669

申请日：2021-01-20

申请人： BASF SE

发明人： Diego SAMPEDRO ,  Raul LOSANTOS ,  Ignacio FUNES-ARDOIZ ,  Thomas EHLIS ,  Jochen GIESINGER ,  Julie GRUMELARD

IPC分类号： A61K8/40 ,  A61P17/16 ,  A61Q17/04 ,  C07C251/02

摘要： The present invention relates to compounds of formula (I) as defined herein. The compounds are suitable for protection against ultraviolet (UV) radiation. Further, the present invention is concerned with compositions comprising at least one compound of formula (I).

公开(公告)号：US20220387389A1

公开(公告)日：2022-12-08

申请号：US17776048

申请日：2020-11-12

申请人： GSK Consumer Healthcare SARL

发明人： Amit SABHERWAL ,  Thierry ATHANASE ,  Sriman BANERJEE

IPC分类号： A61K31/4164 ,  A61P17/16 ,  A61P11/02 ,  A61K9/00 ,  A61K31/045 ,  A61K31/23 ,  A61K31/35 ,  A61K31/569 ,  A61K36/185 ,  A61K36/22 ,  A61K36/47 ,  A61K36/54 ,  A61K36/758 ,  A61K36/899

摘要： A combination product comprising a dispensing head (10, 10′) mounted on a top of a container (20, 20′) containing a formulation for nasal administration, and a solidified skin-care balm (50) for application around the nose contained in a balm holder element (30, 30″) located on a bottom (24) of the container (20).

公开(公告)号：US20220313757A1

公开(公告)日：2022-10-06

申请号：US17616589

申请日：2020-06-05

申请人： LAC2BIOME S.R.L.

发明人： Andrea BIFFI

IPC分类号： A61K35/747 ,  A61K31/728 ,  A61K8/73 ,  A61K8/99 ,  A61P31/00 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A23L33/135

摘要： A composition is described comprising probiotics (live and viable or inactivated bacterial strains) and hyaluronic acid or a salt thereof and related use in prevention, treatment (therapeutic or cosmetic curative) or attenuation of at least one sign or symptom associated with, or caused by, skin aging. Use of the composition is also described in prevention or treatment (therapeutic or cosmetic curative) or attenuation of at least one sign or symptom associated with or caused by a reduction in the immune defences of the skin or by an inflammation/infection of the skin, such as an inflammation induced or caused by UV rays.

公开(公告)号：US20220287937A1

公开(公告)日：2022-09-15

申请号：US17680116

申请日：2022-02-24

申请人： JPB LABS, INC.

发明人： Andrew Shemin

IPC分类号： A61K8/362 ,  A61K31/194 ,  A61K9/00 ,  A61K45/06 ,  A61K47/44 ,  A61K47/12 ,  A61Q19/08 ,  A61P17/16

摘要： An anti-aging serum to slow the aging process by providing fuel to skin cells through topical application of a precursor Krebs cycle intermediate and associated fuel to dampen the effects of aging brought on by cellular replication and metabolism related irregularities. The serum improves skin experiencing mild to moderate wrinkling and mild to moderate mottled hyperpigmentation helping to achieve a more youthful look.

公开(公告)号：US20220023375A1

公开(公告)日：2022-01-27

申请号：US17495611

申请日：2021-10-06

申请人： Wynn Edison Barker

发明人： Wynn Edison Barker

IPC分类号： A61K36/886 ,  A61K36/889 ,  A61K47/02 ,  A61P17/16 ,  A61K9/00 ,  A61P17/02 ,  A61K47/12 ,  A61K9/107 ,  A61K47/46 ,  A61K47/44

摘要： The disclosure relates to a plant based emollient composition. The composition includes coconut oil and an aloe vera plant extract. The composition is useful alone or as a vehicle for small quantities of herbs, vitamins, medications, minerals, vinegars, essential oils (as examples) added during the composition's liquid phase.

公开(公告)号：US20210251869A1

公开(公告)日：2021-08-19

申请号：US17104155

申请日：2020-11-25

申请人： Amazentis SA

发明人： Christopher L. Rinsch ,  Penelope Andreux ,  Anurag Singh

IPC分类号： A61K8/49 ,  A61P17/02 ,  A61P17/18 ,  A61K31/366 ,  A61P17/04 ,  A61K9/06 ,  A61K9/00 ,  A61P17/00 ,  A61P17/06 ,  A61P17/12 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/02

摘要： The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prevention of a skin condition in a subject, wherein the compound of formula (I) or salt thereof is administered topically. The invention further provides topical compostions of a compound of formula (i) and processes for the preparation of said compositions.

公开(公告)号：US11077145B2

公开(公告)日：2021-08-03

申请号：US15562382

申请日：2016-04-01

申请人： STEMMEDICARE CO., LTD.

发明人： Jang Ho Lee

IPC分类号： A61K35/28 ,  C07K14/50 ,  C07K14/525 ,  C07K14/475 ,  C07K14/49 ,  C07K14/78 ,  C07K14/435 ,  C07K14/54 ,  C12N5/00 ,  C07K14/47 ,  A61P17/16 ,  A61K9/00 ,  A61K38/39 ,  C07K14/545

摘要： The present invention relates to the method for mass production of mesenchymal stem cell-derived proteins including various growth factors and cytokines, a mesenchymal stem cell conditioned medium containing a large amount of protein and produced by the above production method, cosmetic composition and pharmaceutical composition including the above conditioned medium for skin regeneration, anti-wrinkle, alopecia treatment, prevention of hair loss and promotion of hair growth. The method for mass production of the mesenchymal stem cell-derived protein of the present invention can greatly increase the amount of various growth factors and proteins which are known to be not expressed from mesenchymal stem cells or expressed only in very small amounts by the existing culture method, and the mesenchymal stem cell conditioned medium prepared by the above method contains a large amount of various kinds of cytokines and growth factors so that it has the excellent effect on skin regeneration, wrinkle improvement, prevention of hair loss, alopecia treatment and hair growth promotion.

公开(公告)号：US20210145945A1

公开(公告)日：2021-05-20

申请号：US17086500

申请日：2020-11-02

申请人： Suzanne J. Paxton-Pierson

发明人： Suzanne J. Paxton-Person

IPC分类号： A61K38/48 ,  A61K33/18 ,  A61K31/122 ,  A61K9/00 ,  A61K31/593 ,  A61K31/465 ,  A61K36/889 ,  A61K31/191 ,  A61K31/375 ,  A61K36/738 ,  A61K31/714 ,  A61K36/16 ,  A61K31/765 ,  A61K33/10 ,  A61K36/82 ,  A61K33/30 ,  A61K31/5685 ,  A61K33/34 ,  A61K36/68 ,  A61K33/44 ,  A61K36/185 ,  A61K31/015 ,  A61K9/70 ,  A61K36/53 ,  A61K31/353 ,  A61K31/198 ,  A61K36/55 ,  A61K31/404 ,  A61K35/02 ,  A61K31/519 ,  A61K33/08 ,  A61K33/26 ,  A61K31/734 ,  A61K9/48 ,  A61K36/736 ,  A61P17/06 ,  A61K33/42 ,  A61K31/197 ,  A61K33/06 ,  A61P17/16 ,  A61K31/194 ,  A61K31/385 ,  A61K38/44 ,  A61K36/05 ,  A61K31/295

摘要： Radioprotection, Radiomitigation and Radiorecovery: Timed use of more widely available antiradiation agents in a kit for subjects affected by ionizing radiation, radiomimetic exposure and radio contamination. The method in the form of strategically timed preemptive and post-irradiation compositions; radioprotection, radiomitigation and radiorecovery formulations are comprised of various available anticorporation, antioxidant, decorporation, multi-mechanistic, pro-survival, pro-hematopoietic, anti-fibrotic and other novel ingredients in synergistic mixtures to be used in critically-timed manners. Radioprotection, radiomitigation and radiorecovery of a mammal prior to, during, just after or well-after exposure to ionizing radiation energy—alpha, beta, neutron, gamma, X-ray and damaging radiofrequency radiation—for long or short periods of time, and exposure to or contamination by radioactive elements or compounds such as radioiodine, radiostrontium, radiophosphorus, radiocobalt, radiocadmium, radiopollonium, radioradium, radiocesium, radiouranium, radioamericium, radiopollonium, radiocerium, radioindium, and the like. Radiomimetic protective method for mucosal exposure is also described.

公开(公告)号：US10973755B2

公开(公告)日：2021-04-13

申请号：US15918979

申请日：2018-03-12

申请人： TCI CO., LTD

发明人： Yung-Hsiang Lin ,  Cheng-Shing Li

IPC分类号： A61K8/96 ,  A61K36/82 ,  A61P17/02 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/08 ,  A61K8/9789

摘要： A method for protecting skin is provided. The method comprises administering to a subject in need a composition, wherein the composition comprises an effective amount of a Camellia sinensis callus extract, and the extract is a polar solvent extract of calluses of Camellia sinensis leaves. The method is especially for nursing skin, repairing skin, improving skin condition, delaying skin aging, assisting in maintaining content of collagen in skin, against photodamage, preventing skin lesions, and/or promoting wound healing.