Preparation of cyclopropane esters
    2.
    发明授权
    Preparation of cyclopropane esters 失效
    制备环丙烷酯

    公开(公告)号:US5731475A

    公开(公告)日:1998-03-24

    申请号:US826650

    申请日:1997-04-04

    摘要: There is disclosed a process for the preparation of a lower alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid which comprises the steps of (a) reacting a compound of formula: CF.sub.3 --CXCl--CH(OH)--CH.dbd.C(CH.sub.3).sub.2 (I) wherein X is chloro or bromo, with a tri-lower-alkyl orthoacetate containing up to four carbon atoms in each alkyl groups in the presence of at least a catalytic amount of an acid catalyst at an elevated temperature for a sufficient time to obtain a compound of formula: CF.sub.3 --CXCl--CH.dbd.CH--C(CH.sub.3).sub.2 --CH.sub.2 CO.sub.2 R (III) wherein R is an alkyl group containing up to four carbon atoms, and (b) treating said compound of formula (III) with at least one molar equivalent of a base to obtain said alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid. The products are useful as intermediates for insecticides.

    摘要翻译: 公开了制备3-(2-氯-3,3,3-三氟丙-1-烯-1-基)-2,2-二甲基环丙烷羧酸的低级烷基酯的方法,该方法包括以下步骤: (a)使其中X是氯或溴的式:CF 3 -CClCl-CH(OH)-CH = C(CH 3)2(I)的化合物与含有至多四个碳原子的三低级烷基原乙酸酯反应 每个烷基在至少一种催化量的酸催化剂存在下在升高的温度下持续足够的时间以获得式CF 3 -CClCl-CH = CH-C(CH 3)2 -CH 2 CO 2 R(III)的化合物,其中 R是含有至多4个碳原子的烷基,和(b)用至少一摩尔当量碱处理式(III)化合物,得到所述3-(2-氯-3,3, 3-三氟丙-1-烯-1-基)-2,2-二甲基环丙烷羧酸。 该产品可用作杀虫剂的中间体。

    Preparation of cyclopropane esters
    3.
    发明授权
    Preparation of cyclopropane esters 失效
    制备环丙烷酯

    公开(公告)号:US5723649A

    公开(公告)日:1998-03-03

    申请号:US776549

    申请日:1997-01-31

    CPC分类号: C07C69/743

    摘要: The invention provides an improved process for the preparation of a lower alkyl ester of 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid in which the corresponding lower alkyl ester of a carboxylic acid selected from 6-bromo-6-chloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid and 6,6-dichloro-3,3-dimethyl-7,7,7-trifluorohept-2-enoic acid is treated with an alkali metal lower alkoxylate in the presence of an aromatic hydrocarbon solvent under conditions under which the lower alcohol of the alkoxylate is removed from the reaction mixture by distillation with the aromatic solvent. The products are useful as intermediates in the manufacture of pyrethroid insecticides.

    摘要翻译: PCT No.PCT / GB95 / 02570 Sec。 371日期1997年1月31日 102(e)日期1997年1月31日PCT提交1995年11月2日PCT公布。 WO96 / 16018 PCT出版物 日期:1996年5月30日本发明提供了制备3-(2-氯-3,3,3-三氟丙-1-烯-1-基)-2,2-二甲基环丙烷羧酸的低级烷基酯的改进方法 其中相应的羧酸的低级烷基酯选自6-溴-6-氯-3,3-二甲基-7,7,7-三氟庚-2-烯酸和6,6-二氯-3-三氟甲基 - 二甲基-7,7,7-三氟庚-2-烯酸在芳族烃溶剂存在下用碱金属低级烷氧基化物处理,在该条件下,通过蒸馏从反应混合物中除去烷氧基化物的低级醇, 芳香族溶剂。 该产品可用作制造拟除虫菊酯杀虫剂的中间体。

    Process for the preparation of 1.R, cis cyclopropane di-carboxylic acid
derivatives
    5.
    发明授权
    Process for the preparation of 1.R, cis cyclopropane di-carboxylic acid derivatives 失效
    制备1.R,顺式环丙烷二羧酸衍生物的方法

    公开(公告)号:US5026862A

    公开(公告)日:1991-06-25

    申请号:US416718

    申请日:1989-10-03

    CPC分类号: C07F9/657181

    摘要: A novel process for the preparation of compounds in all their possible isomeric forms of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 18 carbon atoms, an easily cleavable derivative of the alcohol R-OH and a residue of an alcohol used in the pyrethrinoid series and when Y is --COOR' or --COSR', W is hydrogen and W is halogen when Y is --COOR' and R' is selected from the group consisting of hydrogen, optionally unsaturated alkyl of 1 to 18 carbon atoms and optionally substituted with at least one functional group, aryl optionally substituted with at least one functional group and heterocycle optionally substituted with at least one functional group and when W is hydrogen, the double bond has Z configuration and when W is halogen, the double bond has the E configuration comprising reacting a compound of the formula ##STR2## wherein R has the above definition with a compound of the formula ##STR3## wherein W and Y have the above definitions and A is alkylene of 1 to 18 carbon atoms attached to the two oxygen atoms fixed on the phosphorus atom to obtain a compound of formula I with the double bond having the Z configuration when W is hydrogen and having the E configuration when W is halogen, the cyclopropane and the carboxyl of Y being in both cases in the cis position with respect to the double bond and novel intermediates.

    摘要翻译: 一种用于制备其所有可能的式I化合物的化合物的新方法,其中R选自氢,1至18个碳原子的烷基,醇的易裂解衍生物R-OH 和在拟除虫菊酯类中使用的醇的残基,当Y是-COOR'或-COSR'时,W是氢,当Y是-COOR'时W是卤素,R'选自氢,任选不饱和的 任选被至少一个官能团取代的芳基和任选被至少一个官能团取代的杂环,当W是氢时,该双键具有Z构型,并且当 W是卤素,双键具有E构型,其包括使式II的化合物其中R具有上述定义与式III的化合物反应,其中W和Y具有上述定义 并且A是与固定在磷原子上的两个氧原子连接的1至18个碳原子的亚烷基,以便当W是氢时具有Z构型的双键并且当W是卤素时具有E构型的式I化合物 在两种情况下,Y的环丙烷和羧基在双键的顺式位置和新的中间体。

    Fluorobenzyl esters
    6.
    发明授权
    Fluorobenzyl esters 失效
    氟苄酯

    公开(公告)号:US5017606A

    公开(公告)日:1991-05-21

    申请号:US536078

    申请日:1990-06-11

    申请人: Michael J. Robson

    发明人: Michael J. Robson

    CPC分类号: A01N53/00 C07C33/483

    摘要: Fluorobenzyl esters of the formula: ##STR1## wherein X represents the residue of any carboxylic acid of formula X-COOH which forms an insecticidally active ester with a 3-phenoxybenzyl alcohol, and R, R.sup.6 and R.sup.7 are each selected from hydrogen, halogen and alkyl of up to four carbon atoms, provided that at least one of R, R.sup.6 and R.sup.7 represents halogen, and further provided that R and R.sup.6 are not both bromine when R.sup.7 is hydrogen. The compounds are useful for combatting insect and acarine pests.

    摘要翻译: 式(I)的氟苄基酯,其中X表示与3-苯氧基苄醇形成杀虫活性酯的式X-COOH的任何羧酸的残基,R,R6和R7各自选自氢 卤素和至多四个碳原子的烷基,条件是R,R 6和R 7中的至少一个表示卤素,并且进一步规定当R 7为氢时R和R 6不同时为溴。 这些化合物可用于防治昆虫和螨类害虫。

    Halogenated esters
    8.
    发明授权
    Halogenated esters 失效
    卤代酯

    公开(公告)号:US4853414A

    公开(公告)日:1989-08-01

    申请号:US114732

    申请日:1987-10-30

    CPC分类号: C07C43/23 A01N53/00

    摘要: Compounds of formula (I), useful as insecticides and knockdown agents: ##STR1## where Y is C.sub.1-6 alkoxy, Z is halo or C.sub.1-6 alkoxy; R is --(CH.sub.2).sub.p --(O).sub.m --R.sup.3 where m and p may be 0 or 1; R.sup.3 is C.sub.1-6 alkyl, phenyl or benzyl, or when m is 0, R.sup.3 is C.sub.1-6 alkenyl, haloalkenyl, alkynyl or haloalkynyl, and either (a) A and B are both C.sub.1-4 alkyl or (b) A is hydrogen and B is (R.sup.1)(R.sup.2)C.dbd.CH-- where R.sup.1 and R.sup.2 are selected from methyl, chloro, bromo, fluoro and trifluoromethyl.

    摘要翻译: 用作杀虫剂和敲低剂的式(I)化合物:其中Y是C 1-6烷氧基,Z是卤素或C 1-6烷氧基; R是 - (CH 2)p - (O)m -R 3,其中m和p可以是0或1; R3是C1-6烷基,苯基或苄基,或当m是0时,R3是C1-6链烯基,卤代烯基,炔基或卤代炔基,(a)A和B都是C1-4烷基或(b)A是 氢和B是(R 1)(R 2)C = CH-,其中R 1和R 2选自甲基,氯,溴,氟和三氟甲基。