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    Thiazolothiazole derivatives and organic electronic device using the same
    5.
    发明授权
    Thiazolothiazole derivatives and organic electronic device using the same 有权
    噻唑噻唑衍生物和使用其的有机电子器件

    公开(公告)号：US08304555B2

    公开(公告)日：2012-11-06

    申请号：US12308373

    申请日：2007-06-15

    Applicant: Roman Kiselev ,  Seok-Hee Yoon ,  Hyeon Choi ,  Jae-Min Lee

    Inventor： Roman Kiselev ,  Seok-Hee Yoon ,  Hyeon Choi ,  Jae-Min Lee

    IPC: C07D277/04 ,  C07D277/08

    CPC classification number: H01L51/0036 ,  C08G61/123 ,  C08G61/126 ,  C08G2261/124 ,  C08G2261/3142 ,  C08G2261/3246 ,  C08G2261/364 ,  C08G2261/414 ,  C08G2261/43 ,  C08G2261/91 ,  C08G2261/92 ,  H01B1/127 ,  H01L51/0043 ,  H01L51/0545 ,  Y02E10/549

    Abstract: The present invention relates to novel thiazolothiazole derivatives and an organic electronic device such as an organic light emitting device, an organic transistor, and an organic solar cell using the same. In the compound of the invention, various substituents are introduced to the core structure, so as to satisfy the requirements such as suitable energy levels, and electrochemical and thermal stability, and also have amorphous or crystalline property depending on the kind of the substituents, so as to satisfy the characteristics individually required for each of the devices. Further, an organic semiconductor of p-type or n-type can be fabricated by introducing various substituents to the core structure having a property of n-type. Therefore, the compound of the present invention can provide a device having higher stability.

    Abstract translation: 本发明涉及新颖的噻唑并噻唑衍生物和有机电子器件，例如有机发光器件，有机晶体管和使用其的有机太阳能电池。 在本发明的化合物中，各种取代基被引入到核心结构中，以满足诸如合适的能级，电化学和热稳定性的要求，并且还取决于取代基的种类，具有无定形或结晶性质，因此 以满足每个设备单独需要的特性。 此外，可以通过向具有n型性质的核心结构引入各种取代基来制造p型或n型有机半导体。 因此，本发明的化合物可以提供具有较高稳定性的装置。

    Fluorescent dyes
    6.
    发明授权
    Fluorescent dyes 有权
    荧光染料

    公开(公告)号：US07781187B2

    公开(公告)日：2010-08-24

    申请号：US11324394

    申请日：2005-12-30

    Applicant: Susan Marie Gasper ,  Mingqian He ,  Fang Lai ,  Thomas Mark Leslie ,  Helen Samson

    Inventor： Susan Marie Gasper ,  Mingqian He ,  Fang Lai ,  Thomas Mark Leslie ,  Helen Samson

    IPC: G01N33/52 ,  C07D277/08

    CPC classification number: C07D277/64 ,  C09B23/105 ,  C09B23/145 ,  G01N33/582

    Abstract: Fluorescent dyes useful for detecting a target material in biological assays an electron donating moiety which is linked by a conjugated π-electron bridge to an electron accepting moiety. The π-electron bridge includes at least one carbocyclic ring structure or heterocyclic ring structure. The electron accepting moiety is a carboxylic acid, a salt of a carboxylic acid, or has the formula: wherein:X8 is selected from the group consisting of H, CH3, and (CH2)n6-Z2−, where Z2− is a monovalent anion; and n6 is an integer from 1 through 10; andQ3 is O or S.

    Abstract translation: 用于在生物测定中检测靶材料的荧光染料是通过共轭电极桥与电子接受部分连接的给电子部分。 电子电桥包括至少一个碳环结构或杂环结构。 电子接受部分是羧酸，羧酸盐或具有下式：其中：X 8选自H，CH 3和（CH 2）n6-Z 2 - ，其中Z 2 - 为单价 阴离子 n6为1〜10的整数， Q3是O或S.

    Indole compound
    7.
    发明授权
    Indole compound 有权

    公开(公告)号：US07777047B2

    公开(公告)日：2010-08-17

    申请号：US12382622

    申请日：2009-03-19

    Applicant: Tsuneo Yasuma

    Inventor： Tsuneo Yasuma

    IPC: C07D277/08

    CPC classification number: C07D417/14

    Abstract: The purpose of the present invention is to provide a glucokinase activator useful as a pharmaceutical agent such as an agent for the prophylaxis or treatment of diabetes, obesity and the like.The present invention provides a glucokinase activator containing a compound represented by the formula (I): wherein R1 is a hydrogen atom or a halogen atom; R2 is a group represented by wherein each symbol is defined in the specification, or a salt thereof or a prodrug thereof.

    SUBSTITUTE PYRROLIDINE DERIVATIVES
    8.
    发明申请
    SUBSTITUTE PYRROLIDINE DERIVATIVES 审中-公开
    替代吡咯烷衍生物

    公开(公告)号：US20090053175A1

    公开(公告)日：2009-02-26

    申请号：US12196642

    申请日：2008-08-22

    Applicant: Yat Sun Or ,  Ce Wang ,  Jiang Long ,  Lu Ying ,  Yao-Ling Qiu

    Inventor： Yat Sun Or ,  Ce Wang ,  Jiang Long ,  Lu Ying ,  Yao-Ling Qiu

    IPC: A61K38/21 ,  C07D277/08 ,  C07D263/02 ,  C07D307/02 ,  C07D213/02 ,  A61K38/19 ,  A61P31/12 ,  A61K39/00 ,  A61K31/426 ,  A61K31/42 ,  A61K31/341 ,  A61K31/44

    CPC classification number: C07D417/14 ,  A61K38/21 ,  C07D401/14 ,  C07D403/06 ,  C07D405/14 ,  C07D409/14 ,  C07D413/04 ,  C07D417/04 ,  A61K2300/00

    Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention relates to novel antiviral compounds represented herein above, pharmaceutical compositions comprising such compounds, and methods for the treatment or prophylaxis of viral (particularly HCV) infection in a subject in need of such therapy with said compounds.

    Abstract translation: 本发明公开了式（I）化合物或其药学上可接受的盐，酯或前药：其抑制含RNA病毒，特别是丙型肝炎病毒（HCV）。 因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。 本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。 本发明涉及上文所示的新的抗病毒化合物，包含这些化合物的药物组合物，以及用于治疗或预防需要用所述化合物治疗的受试者中的病毒（特别是HCV）感染的方法。

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