利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

229 records (took 0.015 seconds)

    METHOD FOR MANUFACTURING MULTI-FUNCTIONAL BIO-MATERIAL CONJUGATE USING TWO KINDS OF PARTICLE, AND MULTI-FUNCTIONAL BIO-MATERIAL CONJUGATE MANUFACTURED BY MEANS OF SAME
    91.
    发明申请
    METHOD FOR MANUFACTURING MULTI-FUNCTIONAL BIO-MATERIAL CONJUGATE USING TWO KINDS OF PARTICLE, AND MULTI-FUNCTIONAL BIO-MATERIAL CONJUGATE MANUFACTURED BY MEANS OF SAME 审中-公开
    利用两种粒子制造多功能生物材料共轭物的方法以及通过该方法制造的多功能生物材料共轭物的制造方法

    公开(公告)号：WO2013055142A3

    公开(公告)日：2013-07-04

    申请号：PCT/KR2012008301

    申请日：2012-10-12

    Applicant: KOREA RES INST OF BIOSCIENCE ,  KWANGJU INST SCI & TECH

    Inventor： KIM MIN-GON ,  SUNG YUN JU ,  BYUN JU YOUNG ,  OH YOUNG-KYOUNG ,  JOUNG HYOU-ARM

    IPC: G01N33/553 ,  B82Y15/00 ,  G01N33/569

    CPC classification number: G01N33/54346 ,  B82Y15/00 ,  B82Y40/00 ,  G01N33/54333 ,  G01N33/569 ,  G01N33/587 ,  Y10S977/774

    Abstract: The present invention relates to a method for manufacturing a multi-functional bio-material conjugate, and a multi-functional bio-material conjugate manufactured by means of same, and more specifically, to a method for manufacturing a multi-functional bio-material conjugate used as a biosensor for detecting microorganisms or similar, and a multi-functional bio-material conjugate manufactured by means of same. The method for manufacturing a multi-functional bio-material conjugate comprises: (a) a step for coating protein on a first nano particle having magnetic or fluorescent characteristics; (b) a step for manufacturing a conjugate by adhering a second nano particle having metallic characteristics on the first nano particle, coated with protein; and (c) a step for manufacturing a multi-functional bio-material conjugate by adhering bio-material to the conjugate. By using two kinds of particle, the method for manufacturing a multi-functional bio-material conjugate according to the present invention prevents the precipitation of nano particles, enables bio-material to be easily fixed, and enables the manufacture of a bio-material conjugate having multiple functions. In addition, the multi-functional bio-material conjugate manufactured via said method can be used to detect microorganisms, up to a concentration of 101 cfu.

    Abstract translation: 多功能生物材料缀合物的制造方法和由其制造的多功能生物材料缀合物技术领域本发明涉及一种多功能生物材料缀合物的制造方法以及由其制造的多功能生物材料缀合物，并且更具体地涉及制造多功能生物材料缀合物 用作检测微生物或类似物的生物传感器，以及由其制造的多功能生物材料缀合物。 用于制造多功能生物材料缀合物的方法包括：（a）在具有磁性或荧光特性的第一纳米颗粒上涂布蛋白质的步骤; （b）通过将具有金属特性的第二纳米颗粒粘附在涂布有蛋白质的第一纳米颗粒上来制造缀合物的步骤; 和（c）通过将生物材料粘附到缀合物来制造多功能生物材料缀合物的步骤。 通过使用两种颗粒，根据本发明的制造多功能生物材料缀合物的方法防止了纳米颗粒的沉淀，使生物材料容易固定，并且能够制造生物材料缀合物 具有多种功能。 此外，通过所述方法制造的多功能生物材料偶联物可用于检测浓度高达101cfu的微生物。

    TUBER-TISSUE-SPECIFIC LACCASE PROMOTER DERIVED FROM POTATO, AND USE THEREFOR
    92.
    发明申请
    TUBER-TISSUE-SPECIFIC LACCASE PROMOTER DERIVED FROM POTATO, AND USE THEREFOR 审中-公开
    源自马铃薯的组织特异性漆酶启动子及其用途

    公开(公告)号：WO2013062258A3

    公开(公告)日：2013-06-20

    申请号：PCT/KR2012008417

    申请日：2012-10-16

    Applicant: KOREA RES INST OF BIOSCIENCE

    Inventor： KIM HYUN SOON ,  JEON JAE HEUNG ,  KIM MI SUN

    IPC: C12N15/11 ,  A01H5/10 ,  C12N15/82

    CPC classification number: C07K14/515 ,  C12N15/8226

    Abstract: Provided are: a tuber-tissue-specific laccase promoter derived from potato (Solanum tuberosum); a recombinant plant expression vector comprising the promoter; a plant body that has been genetically modified by means of the recombinant plant expression vector, and seeds thereof; a method of expressing a foreign gene in a fashion specific to tuber tissue in a genetically modified plant body, which method comprises a step of recombining the foreign gene in the recombinant plant expression vector, and a step of genetically modifying the recombinant plant expression vector in the plant body; and a genetically modified plant body wherein a foreign gene produced by means of the method is expressed in a fashion specific to tuber tissue, and seeds thereof.

    Abstract translation: 提供：来源于马铃薯（Solanum tuberosum）的块茎组织特异性漆酶启动子; 包含该启动子的重组植物表达载体; 已经通过重组植物表达载体进行遗传修饰的植物体及其种子; 以经遗传修饰的植物体中的块茎组织特异性的方式表达外源基因的方法，该方法包括将重组植物表达载体中的外源基因重组的步骤，以及将重组植物表达载体在 植物体; 以及遗传修饰的植物体，其中通过该方法产生的外源基因以特定于块茎组织的方式表达，以及其种子。

    COMPOSITION CONTAINING JETBEAD EXTRACTS
    94.
    发明申请
    COMPOSITION CONTAINING JETBEAD EXTRACTS 审中-公开
    含有JETBEAD提取物的组合物

    公开(公告)号：WO2012138190A3

    公开(公告)日：2013-01-10

    申请号：PCT/KR2012002653

    申请日：2012-04-06

    Applicant: KOREA RES INST OF BIOSCIENCE ,  KIM WON GON ,  HAN BAEK SOO ,  KIM KYOUNG SHIM ,  KIM KWANG SOO ,  KIM CHUN HYUNG ,  JUNG HOE YUN ,  KANG YOUNG MI ,  SOHN MI JIN

    Inventor： KIM WON GON ,  HAN BAEK SOO ,  KIM KYOUNG SHIM ,  KIM KWANG SOO ,  KIM CHUN HYUNG ,  JUNG HOE YUN ,  KANG YOUNG MI ,  SOHN MI JIN

    IPC: A61K36/73 ,  A61K36/86 ,  A61P25/16 ,  A61P25/28

    CPC classification number: A61K36/73 ,  A61K36/738

    Abstract: The present invention relates to a pharmaceutical composition containing jetbead extracts as active ingredients for preventing or treating Parkinson's disease, wherein the jetbead extracts are obtained by performing extraction on the stem of the jetbead using an organic solvent. The present invention also relates to food additives which contain jetbead extracts as active ingredients and which exhibit the effects of preventing or treating Parkinson's disease. The jetbead extracts of the present invention may prevent or treat Parkinson's disease without producing any particular side effects, and therefore can be widely used for more safely treating Parkinson's disease.

    Abstract translation: 本发明涉及含有喷射提取物作为预防或治疗帕金森病的活性成分的药物组合物，其中通过使用有机溶剂在喷射珠的茎上进行萃取而获得喷射珠提取物。 本发明还涉及含有喷射提取物作为活性成分并且具有预防或治疗帕金森病的作用的食品添加剂。 本发明的喷射提取物可以预防或治疗帕金森病，而不产生任何特定的副作用，因此可广泛用于更安全地治疗帕金森病。

    PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ASTHMA CONTAINING MAACKIAIN AS AN ACTIVE INGREDIENT
    96.
    发明申请
    PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ASTHMA CONTAINING MAACKIAIN AS AN ACTIVE INGREDIENT 审中-公开
    用于预防或治疗含有作为活性成分的含麦康宁的哮喘的药物组合物

    公开(公告)号：WO2012128496A3

    公开(公告)日：2012-11-15

    申请号：PCT/KR2012001810

    申请日：2012-03-13

    Applicant: KOREA RES INST OF BIOSCIENCE ,  LEE HYEONG KYU ,  AHN KYUNG SEOP ,  JANG HA YOUNG ,  KIM SEMI ,  OH SEI RYANG ,  KIM DOO-YOUNG ,  KIM JUNG HEE

    Inventor： LEE HYEONG KYU ,  AHN KYUNG SEOP ,  JANG HA YOUNG ,  KIM SEMI ,  OH SEI RYANG ,  KIM DOO-YOUNG ,  KIM JUNG HEE

    IPC: A61K31/36 ,  A61K36/48 ,  A61P11/06

    CPC classification number: A61K31/5585 ,  A61K36/48

    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating asthma containing maackiain as an active ingredient. The maackiain of the present invention can be used to advantage as a composition for preventing, treating and alleviating asthma because it has an outstanding effect in suppressing the production of ovalbumin and in particular IgE in serum and bronchoalveolar lavage fluid and in suppressing the expression of Th2 cytokines in the lungs, in addition to suppressing the volume of active oxygen created in the respiratory tract and suppressing the infiltration of inflammatory cells into the bronchi and relieving respiratory-tract hypersensitivity which constitute problems that cause asthma in in-vivo studies.

    Abstract translation: 本发明涉及用于预防或治疗含有麦角新碱作为活性成分的哮喘的药物组合物。 本发明的麻黄碱可用作预防，治疗和缓解哮喘的组合物，因为其在抑制卵清蛋白尤其是血清和支气管肺泡灌洗液中的IgE的产生方面具有突出的作用，并且抑制Th2的表达 除了抑制呼吸道中产生的活性氧的体积并抑制炎症细胞渗入支气管并缓解呼吸道过敏症，这构成了在体内研究中引起哮喘的问题。

    DIFFERENTIATION AND PROLIFERATION METHOD FOR NATURAL KILLER CELLS FROM CD14-POSITIVE MONOCYTES
    98.
    发明申请
    DIFFERENTIATION AND PROLIFERATION METHOD FOR NATURAL KILLER CELLS FROM CD14-POSITIVE MONOCYTES 审中-公开
    CD14阳性单核细胞天然杀伤细胞的分化和增殖方法

    公开(公告)号：WO2012118349A9

    公开(公告)日：2012-10-11

    申请号：PCT/KR2012001587

    申请日：2012-03-02

    Applicant: KOREA RES INST OF BIOSCIENCE ,  CHOI IN PYO ,  YOON SUK RAN ,  KIM MI-JOUNG

    Inventor： CHOI IN PYO ,  YOON SUK RAN ,  KIM MI-JOUNG

    IPC: C12N5/0783 ,  A61K35/12 ,  A61P35/00 ,  C07K14/54

    CPC classification number: A61K35/51 ,  C12N5/0646 ,  C12N2501/2315 ,  C12N2501/2321

    Abstract: The present invention relates to an effective differentiation and proliferation method for natural killer cells (NK cells) from cord blood, and more specifically, to a method for effectively differentiating and proliferating natural killer cells from cord blood, comprising the following steps: 1) removing CD3, CD34, CD56 and CD19 positive cells from cord blood-derived monocytes to prepare CD3-CD34-CD56-CD19 cells; 2) removing CD14-negative cells from the CD3-CD34-CD56-CD19 cells to prepare CD3-CD34-CD56-CD19-CD14-positive cells; and 3) mixing the CD3-CD34-CD56-CD19-CD14-positive cells with IL-15 and IL-21 and culturing the mixture. The present invention can obtain NK cells with a high purity within a short time by inducing NK cells from the CD14-positive cells, compared with a method inducing NK cells from hematopoietic stem cells. In addition, the present invention can induce NK cells with an excellent cell killing activity within a short time so as to differentiate the same into NK cells with a cancer cell killing properties, and thus can be useful for treatment of cancer cells.

    Abstract translation: 本发明涉及脐血自然杀伤细胞（NK细胞）的有效分化和增殖方法，更具体地说，涉及一种从脐带血中有效分化和增殖自然杀伤细胞的方法，包括以下步骤：1）去除 来自脐带血的单核细胞的CD3，CD34，CD56和CD19阳性细胞以制备CD3-CD34-CD56-CD19细胞; 2）从CD3-CD34-CD56-CD19细胞中除去CD14阴性细胞以制备CD3-CD34-CD56-CD19-CD14阳性细胞; 和3）将CD3-CD34-CD56-CD19-CD14阳性细胞与IL-15和IL-21混合并培养该混合物。 本发明与诱导来自造血干细胞的NK细胞的方法相比，通过从CD14阳性细胞诱导NK细胞可以在短时间内获得高纯度的NK细胞。 另外，本发明能够在短时间内诱导具有优异细胞杀伤活性的NK细胞，从而将其分化成具有癌细胞杀伤性质的NK细胞，因此可用于治疗癌细胞。

    CULTIVATION CONTAINER FOR MASS-PRODUCING LIVING ORGANISMS INCLUDING HEALTHY AND SUPERIOR SEED POTATO
    99.
    发明申请
    CULTIVATION CONTAINER FOR MASS-PRODUCING LIVING ORGANISMS INCLUDING HEALTHY AND SUPERIOR SEED POTATO 审中-公开
    用于生产生物体的生殖容器，包括健康和超级种子POTATO

    公开(公告)号：WO2012081848A3

    公开(公告)日：2012-10-11

    申请号：PCT/KR2011009143

    申请日：2011-11-29

    Applicant: KOREA RES INST OF BIOSCIENCE ,  JOUNG HYOUK ,  KIM HYUN KUG ,  KIM HYUN SOON ,  YOUM JUNG WON ,  JEON JAE HEUNG

    Inventor： JOUNG HYOUK ,  KIM HYUN KUG ,  KIM HYUN SOON ,  YOUM JUNG WON ,  JEON JAE HEUNG

    IPC: C12M1/22 ,  C12M1/04 ,  C12M1/12 ,  C12M3/02

    CPC classification number: C12M23/10 ,  A01H4/001 ,  C12M37/04

    Abstract: The present invention relates to a cultivation container for living organisms, and more particularly, to a cultivation container for living organisms which does not become contaminated by external air when cultivating live tissue, and which allows safe and convenient addition or replacement of a medium. The cultivation container for living organisms, according to the present invention, comprises: an outer body, which is provided with an accommodation space having an open top and a coupling protrusion which is formed on the outer circumferential surface; an inner body, which is provided in the accommodation space of the outer body, and has an open top so as to accommodate the medium therein; an inner cover, which couples to the upper portion of the inner body, and is formed with protrusions on the upper surface and a medium insertion hole; and an outer cover, which couples to the upper portion of the outer body, and is formed with a coupling groove that corresponds to the coupling protrusion on the inner circumferential surface and an insertion concave groove that corresponds to the protrusion on the lower surface of the upper portion.

    Abstract translation: 本发明涉及活体生物培养容器，更具体地说，涉及一种生物体培养容器，其在培养活组织时不会被外界空气污染，并且允许安全和方便地添加或更换培养基。 根据本发明的活体生物培养容器包括：外体，其具有开口顶部的容纳空间和形成在外周表面上的联接突起; 内体，其设置在所述外主体的容纳空间中，并且具有开口顶部，以便容纳所述介质; 内盖，其连接到所述内体的上部，并且在所述上表面上形成有突起和介质插入孔; 以及外罩，其与外筒体的上部连结，并且形成有与内周面上的连结突起对应的连结槽，以及对应于下表面上的突出部的插入凹槽 上部。

    Ipomoea batatas-derived ibor-ins gene mutation, and use thereof
    100.
    发明申请
    Ipomoea batatas-derived ibor-ins gene mutation, and use thereof 审中-公开
    来自IPOMOEA BATATAS的IBOR-INS基因的突变及其用途

    公开(公告)号：WO2012070795A3

    公开(公告)日：2012-10-11

    申请号：PCT/KR2011008671

    申请日：2011-11-14

    Applicant: KOREA RES INST OF BIOSCIENCE ,  KWAK SANG SOO ,  LEE HAENG SOON ,  AHN YOUNG OCK ,  JEONG JAE CHEOL ,  KIM SUN HA

    Inventor： KWAK SANG SOO ,  LEE HAENG SOON ,  AHN YOUNG OCK ,  JEONG JAE CHEOL ,  KIM SUN HA

    IPC: A01H5/00 ,  A01H5/10 ,  C12N15/29 ,  C12N15/82

    CPC classification number: C07K14/415 ,  C12N15/825 ,  C12N15/8273

    Abstract: The present invention relates to a method for producing: an IbOr-Ins gene mutation in which a certain sequence is artificially inserted into an Ipomoea batatas-derived IbOrange gene; a recombinant vector including the gene mutation; a host cell mutated by the recombinant vector; and a transformed plant body that has an improved carotenoid content and resistance to saline stress by means of the mutation of the recombinant vector in a plant cell. The present invention also relates to a method for producing a transformed plant body having increased resistance to saline stress using the transformed plant body or seeds thereof produced by the above method and having an improved carotenoid content and resistance to saline stress, and using an Ipomoea batatas-derived IbOrange gene. The invention also relates to a transformed plant body produced by the above method and having increased resistance to saline stress, and to the seeds thereof.

    Abstract translation: 本发明涉及一种产生：IbOr-Ins基因的突变，其中某种序列被人工插入来源于Ipomoea batatas的IbOrange基因中; 包含基因突变的重组载体; 由重组载体突变的宿主细胞; 以及由于重组载体在植物细胞中的突变而具有改善的类胡萝卜素含量和抗盐胁迫性的转化的植物体。 本发明还涉及使用由上述方法生产的转化的植物体或其种子生产具有提高的抗盐胁迫性的转化植物体的方法， 改善的类胡萝卜素和盐胁迫抗性，以及来自Ipomoea batatas的IbOrange基因的使用。 本发明还涉及通过上述方法生产并具有增加的对盐胁迫的抗性的转化植物体及其种子。

Patent Agency Ranking