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    DSP-BASED PACEMAKER WITH IMPROVED EVENT CLASSIFICATION AND MONITORING
    91.
    发明申请
    DSP-BASED PACEMAKER WITH IMPROVED EVENT CLASSIFICATION AND MONITORING 审中-公开
    基于DSP的PACEMAKER具有改进的事件分类和监视

    公开(公告)号：WO00016852A1

    公开(公告)日：2000-03-30

    申请号：PCT/EP1999/006610

    申请日：1999-09-08

    IPC: A61N1/362

    CPC classification number: A61N1/3621 ,  Y10S128/901

    Abstract: There is provided an implantable cardiac pacing system or other cardiac monitoring system, having an enhanced capability of classifying intracardiac signals through a combination of DSP technique and software algorithms. The implantable device has one or more DSP channels corresponding to different signals which are being monitored. Each DSP channel provides for amplification of the incoming signal; conversion from analog to digital form; digital filtering of the converted signals to provide filtered signals; operating on the filtered signals to provide slope signals; determining from the filtered and slope signals whenever an intracardiac event has been detected, e.g., R wave, P wave, etc.; and signal processing of the filtered and slope signals for a predetermined analysis interval after threshold crossing, for generating a plurality of signal parameters. The thus generated signal parameters corresponding to a signal are further operated on by a programmable algorithm to classify the detected event based upon the DSP-generated parameters. By this combination of digital signal processing and programmable software coordinated with each DSP channel, enhanced intracardiac signal classification is achieved.

    Abstract translation: 提供了一种可植入心脏起搏系统或其他心脏监测系统，其具有通过DSP技术和软件算法的组合来增强心脏内信号分类的能力。 该可植入装置具有一个或多个对应于正被监视的不同信号的DSP通道。 每个DSP通道提供输入信号的放大; 从模拟转换为数字形式; 对转换的信号进行数字滤波以提供滤波信号; 对滤波信号进行操作以提供斜率信号; 每当检测到心脏内事件时，例如R波，P波等，从已滤波和斜率信号中确定; 以及在阈值交叉之后的预定分析间隔的滤波和斜率信号的信号处理，用于产生多个信号参数。 由此生成的对应于信号的信号参数进一步由可编程算法进行操作，以便根据DSP生成的参数对检测到的事件进行分类。 通过数字信号处理和与每个DSP通道协调的可编程软件的组合，实现了增强的心内信号分类。

    IMPLANTABLE STIMULATION SYSTEM AND METHOD FOR TERMINATING CARDIAC ARRHYTHMIAS
    92.
    发明申请
    IMPLANTABLE STIMULATION SYSTEM AND METHOD FOR TERMINATING CARDIAC ARRHYTHMIAS 审中-公开
    可植入刺激系统和终止心脏炎症的方法

    公开(公告)号：WO1995009029A2

    公开(公告)日：1995-04-06

    申请号：PCT/US1994010646

    申请日：1994-09-20

    Applicant: SIEMENS PACESETTER, INC.

    Inventor： SIEMENS PACESETTER, INC. ,  WEINBERG, Lisa, P. ,  SHOLDER, Jason, A.

    IPC: A61N00/00

    CPC classification number: A61N1/3621

    Abstract: A cardiac arrhythmia is terminated by stimulating the heart during the narrow "region of susceptibility" or termination window of the arrhythmia cycle based upon a statistically significant starting value. The present invention will store a plurality of successful critically timed intervals and compute a central value (e.g., average, mean, median, etc.) and a measure of variability (sample range, standard deviation, etc.). The measure of variability is used to determine the termination window size. In one embodiment, the present invention then "scans" symmetrically-centrifugally about the statistically significant starting value. In an alternate embodiment, the present invention employs ranked scanning, that is, scanning according to the frequency of occurrence of previously successful starting values. The number and size of steps could be either programmable, or automatically computed by the pulse generator based upon the termination window size. With each successful termination, the statistically significant starting value is updated, thereby providing an intelligent stimulation device which can adapt itself to the patient's ever-changing needs. Histograms of the data could also be displayed on a screen so that the physician could quickly verify the appropriateness of the computed central value and range.

    Abstract translation: 基于具有统计学意义的起始值，在心律失常周期的狭窄“区域”或终止窗口期间刺激心脏来终止心律失常。 本发明将存储多个成功的关键时间间隔并计算中心值（例如，平均值，平均值，中值等）以及可变性度量（样本范围，标准偏差等）。 可变性的度量用于确定终止窗口大小。 在一个实施方案中，本发明随后以关于统计学上显着的起始值的对称地“离心”扫描。 在替代实施例中，本发明使用排序扫描，即根据先前成功的起始值的出现频率进行扫描。 步骤的数量和大小可以是可编程的，或者基于终止窗口大小由脉冲发生器自动计算。 每次成功终止时，更新统计学显着的起始值，从而提供智能刺激装置，以适应患者不断变化的需求。 数据的直方图也可以显示在屏幕上，以便医生可以快速验证计算的中心值和范围的适当性。

    METHOD AND APPARATUS FOR DETECTION AND TREATMENT OF TACHYCARDIA AND FIBRILLATION
    94.
    发明申请
    METHOD AND APPARATUS FOR DETECTION AND TREATMENT OF TACHYCARDIA AND FIBRILLATION 审中-公开
    用于检测和处理TACHYCARDIA和FIBRILLATION的方法和装置

    公开(公告)号：WO1994016767A1

    公开(公告)日：1994-08-04

    申请号：PCT/US1993012221

    申请日：1993-12-15

    Applicant: MEDTRONIC, INC.

    Inventor： MEDTRONIC, INC. ,  KEIMEL, John, G.

    IPC: A61N01/365

    CPC classification number: A61N1/3621 ,  A61N1/3962

    Abstract: An apparatus for detecting, identifying and treating tachyarrhythmias. Tachyarrhythmias are detected and identified by the use of overlapping ranges of intervals. Provisional identification of tachyarrhythmia is accomplished by measuring and tracking intervals within two overlapping or adjacent interval ranges. Further classification and identification of tachyarrhythmias is accomplished by determining the relative numbers of intervals within a preceding series falling within a third interval range, overlapping one or both of the other interval ranges. In response to identification of the tachyarrhythmia, an appropriate therapy is selected and delivered.

    Abstract translation: 一种用于检测，识别和治疗快速性心律失常的装置。 通过使用重叠的间隔范围来检测和鉴定快速性心律失常。 通过测量和跟踪两个重叠或相邻间隔范围内的间隔来实现快速性心律失常的临床鉴定。 快速心律失常的进一步分类和识别是通过确定前一系列中间隔在第三间隔范围内的间隔的相对数量来完成的，该间隔与其他区间范围中的一个或两个重叠。 响应于快速性心律失常的鉴定，选择并递送适当的治疗。

    SYSTEMS AND METHODS FOR TREATING CARDIAC ARRHYTHMIAS
    99.
    发明申请
    SYSTEMS AND METHODS FOR TREATING CARDIAC ARRHYTHMIAS 审中-公开
    治疗心脑血管病的系统与方法

    公开(公告)号：WO2016126613A1

    公开(公告)日：2016-08-11

    申请号：PCT/US2016/015991

    申请日：2016-02-01

    Applicant: CARDIAC PACEMAKERS, INC.

    Inventor： KOOP, Brendan E.

    IPC: A61N1/39 ,  A61N1/362 ,  A61N1/372 ,  A61N1/375 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/0464

    CPC classification number: A61N1/3962 ,  A61B5/042 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/686 ,  A61B5/7246 ,  A61N1/3621 ,  A61N1/3624 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3756 ,  A61N1/3925 ,  A61N1/3987

    Abstract: Systems and methods for treating cardiac arrhythmias are disclosed. In one embodiment, an SICD comprises two or more electrodes, a charge storage device, and a controller operatively coupled to two or more of the electrodes and the charge storage device. In some embodiments, the controller is configured to monitor cardiac activity of the heart of the patient, detect an occurrence of a cardiac arrhythmia based on the cardiac activity, and determine a type of the detected cardiac arrhythmia from two or more types of cardiac arrhythmias. If the determined type of cardiac arrhythmia is one of a first set of cardiac arrhythmia types, the controller sends an instruction for reception by an LCP to initiate the application of ATP therapy by the LCP. If the determined type of cardiac arrhythmia is not one of the first set cardiac arrhythmia types, the controller does not send the instruction.

    Abstract translation: 公开了用于治疗心律失常的系统和方法。 在一个实施例中，SICD包括两个或更多个电极，电荷存储装置和可操作地耦合到两个或更多个电极和电荷存储装置的控制器。 在一些实施例中，控制器被配置为监测患者心脏的心脏活动，基于心脏活动检测心律失常的发生，并且从两种或多种类型的心律不齐确定检测到的心律失常的类型。 如果确定的心律失常类型是第一组心律失常类型之一，则控制器发送由LCP接收的指令以开始由LCP应用ATP治疗。 如果确定的心律失常类型不是第一组心律失常类型之一，则控制器不发送指令。

    ANTI-TACHYARRHYTHMIA SHOCK DETECTION
    100.
    发明申请
    ANTI-TACHYARRHYTHMIA SHOCK DETECTION 审中-公开
    抗TACHYARRHYTHMIA触发检测

    公开(公告)号：WO2016118814A1

    公开(公告)日：2016-07-28

    申请号：PCT/US2016/014443

    申请日：2016-01-22

    Applicant: MEDTRONIC, INC.

    Inventor： REINKE, James D. ,  ROLINE, Glenn M. ,  HOSSAIN, Shohan T. ,  HEINKS, Michael W.

    IPC: A61N1/37 ,  A61N1/36 ,  A61N1/39

    CPC classification number: A61N1/3962 ,  A61N1/3621 ,  A61N1/3624 ,  A61N1/37 ,  A61N1/3756 ,  A61N1/3937

    Abstract: An implantable pacemaker detects delivery of an anti-tachyarrhythmia shock by another device. The implantable pacemaker delivers cardiac stimulation therapy within a patient. The implantable pacemaker senses, via the electrode pair, an electrical signal. The implantable pacemaker detects the anti-tachyarrhythmia shock based on the sensed electrical signal by detecting DC voltage polarization across the electrode pair within the patient. The implantable pacemaker alters the cardiac stimulation therapy based on the detected anti-tachyarrhythmia shock.

    Abstract translation: 植入式起搏器检测另一装置的抗快速性心律失常性休克的传递。 植入式起搏器在患者体内提供心脏刺激治疗。 植入式起搏器通过电极对感测电信号。 可植入心脏起搏器通过检测患者内的电极对上的直流电压偏振来检测基于感测到的电信号的抗快速性心律失常性休克。 植入式起搏器基于检测到的抗快速性心律失常休克改变心脏刺激疗法。

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