METHOD OF PREPARATION OF PRODUCTS WHICH ABSORB WATER INTERMOLECULARLY
    93.
    发明申请
    METHOD OF PREPARATION OF PRODUCTS WHICH ABSORB WATER INTERMOLECULARLY 审中-公开
    吸收水分子内产物的制备方法

    公开(公告)号:WO99021897A1

    公开(公告)日:1999-05-06

    申请号:PCT/GR1998/000027

    申请日:1998-10-23

    Abstract: A method of crosslinking polystyrene polymers and co-polymers for the formation of macroplegmatic materials of an Mc 30,000 to 50,000 is described. The materials forming an insoluble gel which is shaped in an extruder to 3 to 5 cm pieces and is subject to sulphonation with dense sulphuric acid, with oleum sulphuric acid with sulphur trioxide and with chlorosulphonic acid, and the introduction of sulphonic groups to a high density and with the introduction of nitric group and with the introduction of carboxylic group with the copolymer styrene-acrylonitrile. The chlorosulfonic group promotes sulphonation and crosslinking with the formation of bridges with the sulfone group which is controlled with a 10-20 % of acetic acid present as regulator and an insoluble volume of gel is formed which following drainage of the solvent and after remaining to ripen for 4-7 hours it is treated with ethanol or propanol to extract the unreacted chlorosulphonic acid then is neutralised with sodium or potassium hydroxide subjected to an extruder for the preparation of 3-5 cm products. Following neutralisation and shrinkage to a 10 % water content and the products produced are deodorised at a temperature of 160 DEG C under vacuum and are converted to materials which absorb water inside their molecules up to 300 times their weight; having an inorganic content of 72-75 % they exhibit a high degree of stability in the ground, they do not degrade and can be used indefinitely for water absorption-release so that they operate as fertility promoters to any type of soil leading to an increase of green growth, and to the planting of trees and forests and to advance food production.

    Abstract translation: 描述了将聚苯乙烯聚合物和共聚物交联以形成Mc 30,000至50,000的主要物质材料的方法。 形成不溶性凝胶的材料,其在挤出机中成形为3至5cm,并且用致密硫酸与发烟硫酸与三氧化硫和氯磺酸进行磺化,并且将磺基引入高密度 并引入硝酸和引入羧基与共聚物苯乙烯 - 丙烯腈。 氯磺基团促进磺化和交联,形成与磺基组的桥接,其中用作为调节剂的10-20%的乙酸控制,形成不溶性体积的凝胶,随后引入溶剂并保持成熟 4-7小时,用乙醇或丙醇处理以提取未反应的氯磺酸,然后用经过挤出机的氢氧化钠或氢氧化钾中和以制备3-5cm的产物。 中和收缩至10%含水量后,所生产的产品在真空下在160℃的温度下进行除臭,并转化为吸收其分子内水分达到其重量的300倍的物质; 无机含量为72-75%,它们在地面表现出高度的稳定性,它们不会降解,并且可以无限期地用于吸水释放,使得它们作为生育促进剂作用于任何类型的土壤,导致增加 绿色增长,种植树木和森林,促进粮食生产。

    MODIFICATION OF POLYPEPTIDES
    95.
    发明申请
    MODIFICATION OF POLYPEPTIDES 审中-公开
    多肽的改性

    公开(公告)号:WO1996040792A1

    公开(公告)日:1996-12-19

    申请号:PCT/DK1996000250

    申请日:1996-06-07

    Inventor: NOVO NORDISK A/S

    Abstract: The invention relates to a process for producing polymer-polypeptide conjugates with reduced immunogenicity comprising the steps of: a) generating a polymer halogen formiate; and b) conjugating at least one polymer-halogen formiate to at least one attachment group on the polypeptide (Pep). The invention also relates to a polymer-polypeptide conjugate with reduced immunogenicity, an activated polymer for conjugating polypeptides (Pep), and the use of said process for reducing the immunogenicity of polypeptides used for pharmaceutical and/or industrial applications. Finally it is the object of the invention to provide the use of said polymer-polypeptide conjugate for a number of therapeutic and industrial purposes, such as the use in pharmaceuticals, personal care products and detergent compositions.

    Abstract translation: 本发明涉及具有降低的免疫原性的聚合物 - 多肽缀合物的制备方法,包括以下步骤:a)产生聚合物卤素甲酸酯; 和b)将至少一种聚合物 - 卤素甲酸酯与多肽(Pep)上的至少一个连接基团缀合。 本发明还涉及具有降低的免疫原性的聚合物 - 多肽缀合物,用于缀合多肽的活化聚合物(Pep),以及用于降低用于制药和/或工业应用的多肽的免疫原性的所述方法的用途。 最后,本发明的目的是提供所述聚合物 - 多肽缀合物在许多治疗和工业目的中的用途,例如在药物,个人护理产品和洗涤剂组合物中的用途。

    PROCESS FOR PRODUCING POLYOLEFIN HAVING TERMINAL FUNCTIONAL GROUP
    97.
    发明申请
    PROCESS FOR PRODUCING POLYOLEFIN HAVING TERMINAL FUNCTIONAL GROUP 审中-公开
    生产具有终端功能团的聚烯烃的方法

    公开(公告)号:WO1996011958A1

    公开(公告)日:1996-04-25

    申请号:PCT/JP1995002081

    申请日:1995-10-12

    CPC classification number: C08F8/00 C08F110/06 C08F8/18

    Abstract: A process for producing a polyolefin having a terminal functional group in an industrially advantageous manner, comprising the step (A) of producing a terminally modified polyolefin of the general formula P-AlR R (wherein P represents a polymer chain, and R and R represent each a C1-C10 hydrocarbon group, etc.) in the presence of an olefin polymerization catalyst prepared from a solid titanium catalyst component (a), an organoaluminum compound (b), and optionally an organosilicon compound (c) and the step (B) of either conducting a substitution reaction between the -AlR R group of the polyolefin obtained in the step (A) and a compound having a functional structure, or conducting a substitution reaction between the -AlR R group of the polyolefin obtained in the step (A) and a compound having a structure capable of forming a functional group by solvolysis, followed by the solvolysis of the reaction product to yield a polyolefin of the general formula P-X (wherein P is as defined above, and X represents a functional group). The obtained polyolefin is useful as, for example, a compatibilizer for polymer blends and a starting material for molecular design.

    Abstract translation: 一种以工业上有利的方式制备具有末端官能团的聚烯烃的方法,包括制备通式为P-AlR 1 R 2的末端改性聚烯烃的步骤(A)(其中P表示聚合物链 在由固体钛催化剂组分(a),有机铝化合物(b)制备的烯烃聚合催化剂存在下,R 1和R 2各自代表C1-C10烃基等) 任选的有机硅化合物(c)和在步骤(A)中获得的聚烯烃的-AlR 1 R 2基团与具有官能结构的化合物之间进行取代反应的步骤(B),或 在步骤(A)中获得的聚烯烃的-AlR 1 R 2基团与通过溶剂分解形成官能团的结构的化合物之间进行取代反应,然后将反应产物溶解分解成 得到通式PX的聚烯烃(其中P i s,X表示官能团)。 所得聚烯烃可用作例如聚合物共混物的增容剂和用于分子设计的原料。

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