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公开(公告)号：WO2014121159A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014345
申请日：2014-02-01
Applicant: MEDTRONIC, INC. , MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
Inventor： MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
IPC: A61M1/14
CPC classification number: A61M1/1619 , A61M1/1605 , A61M1/1609 , A61M1/1696 , A61M1/28 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2230/20
Abstract: A system for measuring at least one fluid characteristic at various stages within a sorbent system has a sorbent cartridge that has at least one material layer and at least one fluid passageway in at least one location in the sorbent system to provide a diverted sample stream from the various stages. At least one fluid characteristic of the diverted sample stream is measured.
Abstract translation: 用于在吸附剂系统内的各个阶段测量至少一种流体特性的系统具有吸附剂筒，其在吸附剂系统中的至少一个位置具有至少一个材料层和至少一个流体通道，以提供从 各个阶段 测量转向的样品流的至少一种流体特性。
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公开(公告)号：WO2014121157A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014343
申请日：2014-02-01
Applicant: MEDTRONIC, INC. , MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
Inventor： MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
CPC classification number: A61M1/1621 , A61M1/1601 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1668 , A61M1/3465 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649
Abstract: A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD having a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject; the controlled compliant flow path having a means for selectively metering in and metering out fluid from the flow path.
Abstract translation: 用于血液透析，血液透析滤过和血液滤过的流动回路，用于治疗病理状况，如终末期肾脏疾病（ESRD，具有用于从水进行血液透析治疗期间所需的用于制备流体的受控顺应流动路径。受控制的顺应性流动路径将水改为任何 用于引发血液透析系统的解决方案之一，用于接触血液的生理上相容的溶液，用于输注到受试者的生理学相容溶液和用于血液冲洗回到受试者的溶液;受控顺应性流动路径，具有用于选择性测量 并从流路计量出流体。
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公开(公告)号：WO2017019642A2
公开(公告)日：2017-02-02
申请号：PCT/US2016/043950
申请日：2016-07-25
Applicant: MEDTRONIC, INC. , LURA, David, B. , HOBOT, Christopher, M. , GERBER, Martin, T. , MEYER, Thomas, E.
Inventor： LURA, David, B. , HOBOT, Christopher, M. , GERBER, Martin, T. , MEYER, Thomas, E.
IPC: A61M1/16
CPC classification number: A61M1/169 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/267 , A61M39/12 , A61M39/223 , A61M2205/3337 , A61M2205/6018 , A61M2209/08 , A61M2209/082
Abstract: The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.
Abstract translation: 本发明涉及用于与可拆卸容器一起使用的流体流动路径和流体连接器，该可分离容器可以坐落在用于透析机中的输液管道中。 可拆卸的容器可以容纳输入物或其他溶质或材料，例如消毒剂或清洁剂，并且可以方便地安置在输液罐中。 根据需要，可拆卸的容器可从输液罐中取出，用于补充，清洗或补给。 输液罐可以定位或坐在透析机的接收室中，并且还可以根据需要移除。 本发明的流体路径和流体连接器提供了所需的流体配件，阀门装置，泵和用于使用输送槽的桨组件。
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公开(公告)号：WO2014121167A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014355
申请日：2014-02-02
Applicant: MEDTRONIC, INC. , PUDIL, Bryant, J. , GERBER, Martin, T. , LURA, David, B , MEYER, Thomas, E.
Inventor： PUDIL, Bryant, J. , GERBER, Martin, T. , LURA, David, B , MEYER, Thomas, E.
IPC: A61M1/14
CPC classification number: A61M1/1696 , A61M1/16 , A61M1/1605 , A61M1/165 , A61M1/287 , A61M1/34 , A61M1/3406 , A61M1/3413 , A61M1/3437 , A61M2205/33 , A61M2205/3324 , A61M2205/50
Abstract: Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer.
Abstract translation: 用于在血液透析治疗期间管理透析液的pH的系统和方法。 系统和方法调节透析液pH和缓冲液浓度，以在进入透析器的透析液中产生预定的总碳酸氢盐缓冲液浓度。
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15.发明申请MODULAR FLUID THERAPY SYSTEM HAVING JUMPERED FLOW PATHS AND SYSTEMS AND METHODS FOR CLEANING AND DISINFECTION 审中-公开具有流体流动和系统的模块化流体治疗系统和清洁和消毒方法
公开(公告)号：WO2014121166A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014352
申请日：2014-02-01
Applicant: MEDTRONIC, INC. , MEYER, Thomas, E. , LURA, David, B. , PUDIL, Bryant, J. , GERBER, Martin, T. , DANIELS, Mark, F.
Inventor： MEYER, Thomas, E. , LURA, David, B. , PUDIL, Bryant, J. , GERBER, Martin, T. , DANIELS, Mark, F.
CPC classification number: A61M1/16 , A61M1/1605 , A61M1/165 , A61M1/169 , A61M1/1696 , A61M1/3413 , A61M1/3437 , A61M1/3609 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2209/06
Abstract: Systems and methods for cleaning and disinfecting a medical therapy device that delivers any one of hemodialysis, hemodiafiltration, and hemofiltration. The system has a base module that has at least one segment of a controlled compliant flow path and at least one pair of jumpered ports configured on the base module. One or more components have connections connectable to the jumpered ports of the base module to provide for fluid communication between the segment of the controlled compliant flow path in the base module and a flow path defined by the one or more components. The base module is connected to the one or more components that define a flow path configurable for carrying out in part at least one function performed during any one of hemodialysis, hemodiafiltration or hemofiltration.
Abstract translation: 用于清洁和消毒输送血液透析，血液透析滤过和血液滤过中的任何一种的医疗治疗装置的系统和方法。 该系统具有基本模块，该基本模块具有被控制的兼容流动路径的至少一个段和配置在基本模块上的至少一对跳接端口。 一个或多个组件具有可连接到基本模块的跨接端口的连接，以提供在基本模块中受控制的兼容流动路径的段与由一个或多个组件限定的流动路径之间的流体连通。 基座模块连接到一个或多个部件，其限定可以部分地执行血液透析，血液透析过滤或血液滤过中的任何一个期间执行的至少一个功能的流路。
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Patent Agency Ranking
公开(公告)号：WO2013025844A2
公开(公告)日：2013-02-21
申请号：PCT/US2012/051011
申请日：2012-08-15
Applicant: MEDTRONIC, INC. , KELLY, Thomas D. , LYU, SuPing , PUDIL, Bryant J. , MEYER, Thomas E.
Inventor： KELLY, Thomas D. , LYU, SuPing , PUDIL, Bryant J. , MEYER, Thomas E.
CPC classification number: A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1696 , A61M1/3609 , A61M1/3612 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/50 , A61M2230/207
Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.
Abstract translation: 用于进行具有或使用透析器，对照组分，吸附剂盒和流体储存器的肾替代疗法的设备，系统和方法，所述透析器，对照组分，吸附剂盒和流体储存器被构造为适于佩戴或携带的重量和尺寸 由需要治疗的个体进行披露。 该系统具有受控的符合性透析回路，其中控制泵控制流体穿过透析膜的双向移动。 提供第一吸附剂盒用于具有活性炭和氧化锆的便携式处理模块。 该系统还提供了对含有脲酶的吸附剂盒的入口和出口电导率的监测，以提供量化或监测通过可拆卸的尿素去除模块去除尿素的设施。
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公开(公告)号：WO2014121164A1
公开(公告)日：2014-08-07
申请号：PCT/US2014/014350
申请日：2014-02-01
Applicant: MEDTRONIC, INC. , MEYER, Thomas, E. , LURA, David, B. , PUDIL, Bryant, J. , GERBER, Martin, T.
Inventor： MEYER, Thomas, E. , LURA, David, B. , PUDIL, Bryant, J. , GERBER, Martin, T.
CPC classification number: A61M1/1621 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/165 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1676 , A61M1/169 , A61M1/1696 , A61M1/3413 , A61M1/3437 , A61M1/3609 , A61M1/3626 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3649 , A61M1/365 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2209/06 , A61M2230/65
Abstract: Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.
Abstract translation: 用于控制受试者和受控顺应流动路径之间的流体运动和流体体积的系统和方法。 受控制的柔性流动路径具有用于选择性地计量来自受控制的顺应流动路径的流体的计量装置。 体外流路与跨过半透膜的受控顺应性流动路径流体连通，其中体外流路具有第一末端和第二末端。
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18.发明申请
公开(公告)号：WO2013019994A3
公开(公告)日：2013-04-25
申请号：PCT/US2012049398
申请日：2012-08-02
Applicant: MEDTRONIC INC , KELLY THOMAS D , LYU SUPING , PUDIL BRYANT J , MEYER THOMAS E
Inventor： KELLY THOMAS D , LYU SUPING , PUDIL BRYANT J , MEYER THOMAS E
CPC classification number: A61M1/3482 , A61M1/1696 , A61M2202/0021 , A61M2202/0413
Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.
Abstract translation: 公开了用于执行肾脏替代疗法的系统和方法，其具有或使用透析器，控制组件，吸附剂盒和流体储存器，其被配置为适于被需要治疗的个体穿戴或携带的重量和尺寸。 用于执行肾脏替代治疗的系统具有受控的依从性透析电路，其中控制泵控制流体穿过透析膜的双向运动。 透析电路和用于循环血液的体外循环通过透析膜流体连通。 在体外循环和透析回路之间移动的流体通量由控制泵运行的速率改变，从而可以控制超滤速率和对流间隙。 该系统提供对吸附剂盒的入口和出口导电性的监测，以提供量化或监测吸附剂盒去除尿素的设施。
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公开(公告)号：WO2017019642A3
公开(公告)日：2017-03-09
申请号：PCT/US2016043950
申请日：2016-07-25
Applicant: MEDTRONIC INC , LURA DAVID B , HOBOT CHRISTOPHER M , GERBER MARTIN T , MEYER THOMAS E
Inventor： LURA DAVID B , HOBOT CHRISTOPHER M , GERBER MARTIN T , MEYER THOMAS E
IPC: A61M1/16
CPC classification number: A61M1/169 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/267 , A61M39/12 , A61M39/223 , A61M2205/3337 , A61M2205/6018 , A61M2209/08 , A61M2209/082
Abstract: The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.
Abstract translation: 本发明涉及用于可拆卸容器的流体流动路径和流体连接器，所述可拆卸容器可安放在输注容器中用于透析机中。 可拆卸的容器可以包含输注液或其他溶质或材料，例如消毒剂或清洁剂，并且可以方便地坐在输注容器中。 根据需要，可以将可分离的容器从输注容器中取出以进行补充，清洁或再补给。 输注容器可以被放置或安置在透析机的接收室中，并且也可以根据需要被移除。 本发明的流体路径和流体连接器提供了用于使用注入液盒的所需的流体配件，阀装置，泵和桨叶组件。
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20.发明申请
公开(公告)号：WO2015080895A1
公开(公告)日：2015-06-04
申请号：PCT/US2014/065950
申请日：2014-11-17
Applicant: MEDTRONIC, INC. , PUDIL, Bryant, J. , GERBER, Martin, T. , LURA, David, B. , MEYER, Thomas, E.
Inventor： PUDIL, Bryant, J. , GERBER, Martin, T. , LURA, David, B. , MEYER, Thomas, E.
CPC classification number: A61M1/14 , A61M1/1605 , A61M1/1696 , A61M2205/3306 , A61M2205/3334 , A61M2205/50 , B01J20/00 , B01J20/0211 , B01J20/0292 , B01J20/06 , B01J20/08 , B01J20/20 , B01J20/28052 , B01J20/3433 , B01J39/08 , B01J39/12 , B01J2220/42 , B01J2220/46 , B01J2220/62
Abstract: A detachable module for optionally recharging sorbent materials, including zirconium phosphate, with an optional bypass and conduits for a sorbent cartridge. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged.
Abstract translation: 可拆卸模块，用于可选地对包括磷酸锆在内的吸附剂材料进行再充电，其中可选旁路和用于吸附剂盒的导管。 吸附剂盒可以具有包含连接每个模块的连接器的一个或多个模块。 一个或多个模块可以是可重复使用的，并且其中的吸附剂材料被再充电。
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