公开(公告)号：WO2016187456A1

公开(公告)日：2016-11-24

申请号：PCT/US2016/033335

申请日：2016-05-19

Applicant: GRAVITAS MEDICAL, INC.

Inventor： SUTARIA, Saheel ,  BENNETT-GUERRERO, Eliott ,  ELIASON, Braden ,  SPIVY, Arthur ,  BURNETT, Daniel R.

IPC: A61B5/053 ,  A61B5/00 ,  A61B5/03 ,  A61B5/0488 ,  A61B5/103 ,  A61B5/145

CPC classification number: A61B5/4238 ,  A61B5/00 ,  A61B5/01 ,  A61B5/03 ,  A61B5/0422 ,  A61B5/0488 ,  A61B5/05 ,  A61B5/053 ,  A61B5/0536 ,  A61B5/0538 ,  A61B5/065 ,  A61B5/068 ,  A61B5/0816 ,  A61B5/103 ,  A61B5/1073 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/4205 ,  A61B5/4211 ,  A61B5/4233 ,  A61B5/4836 ,  A61B5/6852 ,  A61B5/6898 ,  A61B5/7282 ,  A61B5/746 ,  A61B7/00 ,  A61B7/003 ,  A61B7/04 ,  A61B17/12136 ,  A61B2562/0204 ,  A61B2562/043 ,  A61J15/0084 ,  A61J15/0088 ,  A61M1/008 ,  A61M2205/3324 ,  A61M2210/105 ,  A61M2210/1053

Abstract: Methods and apparatus for guiding medical care based on sensor data from the gastrointestinal tract are described utilizing an apparatus which can be used with enteral feeding. Generally, the apparatus includes an elongated body having a length configured for insertion into a stomach and at least one pair of electrodes located along the length of the elongated body and positionable for placement within the stomach. A controller in electrical communication with the at least one pair of electrodes is included and the control may also be configured to measure a conductivity or impedance between the pair of electrodes and to determine a gastric residual volume of the stomach based on the measured conductivity or impedance.

Abstract translation: 使用可与肠内喂养一起使用的装置描述基于来自胃肠道的传感器数据来指导医疗护理的方法和装置。 通常，该装置包括细长体，其具有构造成用于插入胃的长度和沿着细长主体的长度定位的至少一对电极，并且可定位以放置在胃内。 包括与所述至少一对电极电连通的控制器，并且所述控制还可以被配置为测量所述一对电极之间的电导率或阻抗，并且基于所测量的电导率或阻抗来确定胃的胃残留体积 。

公开(公告)号：WO2015195783A3

公开(公告)日：2016-02-11

申请号：PCT/US2015036201

申请日：2015-06-17

Applicant: ARIA CV INC

Inventor： VOLLMERS KARL ,  SCANDURRA JOHN

IPC: A61M39/02 ,  A61M1/10

CPC classification number: A61M1/1086 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12136 ,  A61B2017/00022 ,  A61B2017/00212 ,  A61B2017/00221 ,  A61B2090/064 ,  A61M1/1044 ,  A61M1/1072 ,  A61M1/125 ,  A61M5/1723 ,  A61M5/5086 ,  A61M25/04 ,  A61M25/0662 ,  A61M25/104 ,  A61M29/02 ,  A61M39/0208 ,  A61M2025/0681 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/3324 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3389 ,  A61M2205/3515 ,  A61M2205/3523 ,  A61M2205/505 ,  A61M2210/12 ,  A61M2230/04

Abstract: A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

Abstract translation: 提供了一种用于治疗心脏病的系统，例如肺动脉高压或右心衰竭，包括可植入组件和用于监测可植入组件的外部组件。 可植入部件可以包括通过导管联接到储存器的柔顺构件，例如球囊。 优选地，顺应性构件适于植入肺动脉中，并且储库适于被皮下植入。 外部部件可以包括临床控制器组件，被配置为运行临床医生的计算机的监视软件，患者监视设备和被配置为在患者的移动设备上运行的移动应用。

公开(公告)号：WO2015071247A1

公开(公告)日：2015-05-21

申请号：PCT/EP2014/074240

申请日：2014-11-11

Applicant: GAMBRO LUNDIA AB

Inventor： HOBRO, Sture

IPC: A61M1/16

CPC classification number: A61M1/1662 ,  A61L2/04 ,  A61L2202/24 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/166 ,  A61M1/1664 ,  A61M1/1686 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3368 ,  A61M2205/3393 ,  A61M2205/36 ,  A61M2205/50 ,  A61M2205/8206

Abstract: A dialysis monitor with a treatment fluid path configured to provide treatment fluid to a dialyzer when dialysis treatment is performed by the dialysis monitor is provided. A battery unit is connected to a controller and at least a portion of the functional elements of the dialysis monitor in order to provide back-up power should the supply of external power be discontinued. Energy of the battery unit is used to provide energy to the heater in preparation for and/or at least partly during thermal disinfection of the treatment fluid path or when starting up the preparation of treatment fluid thereby shortening the time required for the thermal disinfection and the starting up of the preparation of treatment fluid, respectively.

Abstract translation: 本发明提供了一种具有治疗流体路径的透析监测器，其被配置为在通过透析监测器进行透析治疗时向透析器提供治疗流体。 电池单元连接到控制器和透析监视器的功能元件的至少一部分，以便在停止供应外部电力时提供备用电力。 电池单元的能量用于向加热器提供能量以及/或至少部分地在处理流体路径的热消毒期间或者当启动处理流体的制备时，从而缩短热消毒所需的时间和 分别开始处理液的制备。

公开(公告)号：WO2015017609A2

公开(公告)日：2015-02-05

申请号：PCT/US2014/049031

申请日：2014-07-31

Applicant: ALCYONE LIFESCIENCES, INC.

Inventor： SINGH, Deep, Arjun ,  ANAND, Pj ,  EAST, Andrew

IPC: A61M31/00 ,  A61M25/02

CPC classification number: A61B5/6849 ,  A61B5/4839 ,  A61B5/6852 ,  A61B5/6868 ,  A61B5/6882 ,  A61B18/1492 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00744 ,  A61B2090/062 ,  A61B2562/0209 ,  A61B2562/166 ,  A61B2562/222 ,  A61M39/0247 ,  A61M2039/025 ,  A61M2039/0261 ,  A61M2039/0273 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2210/0687 ,  A61M2230/005 ,  A61M2230/50 ,  A61N1/0529 ,  A61N1/36017 ,  A61N1/36025

Abstract: Systems and methods for delivering a drug or other therapy over an extended period of time (e.g., several hours, days, weeks, months, years, and so forth) are disclosed herein, as are systems and methods for monitoring various parameters associated with the treatment of a patient. Systems and methods are also disclosed herein that generally involve CED devices with various features for reducing or preventing backflow.

Abstract translation: 本文公开了用于在延长的时间段（例如，数小时，数天，数周，数月，数年等）内递送药物或其他疗法的系统和方法，以及系统和方法 用于监测与治疗患者相关的各种参数的方法。 本文还公开了系统和方法，其通常涉及具有用于减少或防止回流的各种特征的CED装置。

公开(公告)号：WO2014149744A1

公开(公告)日：2014-09-25

申请号：PCT/US2014/020675

申请日：2014-03-05

Applicant: FRESENIUS MEDICAL CARE HOLDINGS, INC.

Inventor： TUCKWELL, Mark David

IPC: A61B5/00 ,  A61M1/00 ,  G01N33/49

CPC classification number: A61M1/16 ,  A61B5/055 ,  A61B5/145 ,  A61M1/1605 ,  A61M1/1619 ,  A61M1/3609 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/50 ,  G01F1/586 ,  G01N27/023 ,  G01N33/49

Abstract: This disclosure relates to medical fluid sensors and related systems and methods. In some aspects, a circuit includes a radio frequency coil tuned to at least one frequency and at least one switching circuit directly connected to the radio frequency coil. The radio frequency coil is characterized by a high impedance.

Abstract translation: 本公开涉及医疗流体传感器及相关系统和方法。 在一些方面，电路包括调谐到至少一个频率的射频线圈和直接连接到射频线圈的至少一个开关电路。 射频线圈的特征在于高阻抗。

公开(公告)号：WO2014121158A1

公开(公告)日：2014-08-07

申请号：PCT/US2014/014344

申请日：2014-02-01

Applicant: MEDTRONIC, INC. ,  MEYER, Thomas, E. ,  LURA, David, B. ,  PUDIL, Bryant, J. ,  GERBER, Martin, T.

Inventor： MEYER, Thomas, E. ,  LURA, David, B. ,  PUDIL, Bryant, J. ,  GERBER, Martin, T.

IPC: A61M1/14 ,  A61M1/16

CPC classification number: A61M1/3627 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/165 ,  A61M1/1658 ,  A61M1/1666 ,  A61M1/3609 ,  A61M1/3626 ,  A61M5/36 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/7536 ,  A61M2209/00 ,  B01D19/0031

Abstract: A degassing module for removal of air and other gases during operation of a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The degassing module has a flow-through first chamber that has a hydrophobic vent membrane that has an exterior and interior side forming a portion of the flow-through chamber. The hydrophobic vent membrane is positioned at a higher elevation on the flow- through chamber than a fluid outlet. Fluid flows through the flow-through chamber in a downward direction relative to the hydrophobic vent membrane. A flow-through chamber has a cross sectional area configured to provide for a downward flow velocity of the fluid to be less than the upward rise velocity of a smallest bubble to be removed from the fluid.

Abstract translation: 用于在输送任何一种血液透析，血液透析滤过和血液滤过的医疗治疗装置的操作期间去除空气和其它气体的脱气模块。 脱气模块具有流过第一室，其具有疏水排气膜，其具有形成流通室的一部分的外部和内侧。 疏水排气膜在流通室上的位置比流体出口更高。 流体相对于疏水通气膜沿向下的方向流过流通室。 流通室具有被配置为提供流体的向下流动速度的横截面积小于要从流体移除的最小气泡的向上升速。

公开(公告)号：WO2013175547A1

公开(公告)日：2013-11-28

申请号：PCT/JP2012/062912

申请日：2012-05-21

Applicant: 愛知時計電機 株式会社 ,  鈴木 英之

Inventor： 鈴木　英之

IPC: G01F1/58 ,  A61M1/14

CPC classification number: G01F1/58 ,  A61M1/16 ,  A61M1/1647 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/3368 ,  G01F1/588 ,  G01F15/02

Abstract: 　ベース（４１）は、複数の流路（３３，３４）と、流路（３３，３４）に流れる流体の流量を検出するための検出部（５３１，５４１）とを備えている。ベース（４１）において流路（３３，３４）間には、流路（３３，３４）間の熱伝導を遮断するための遮断部（５７）が設けられている。遮断部（５７）は、ベース（４１）に形成された溝（５８）からなる。

Abstract translation: 底座（41）设置有多个流动通道（33,34）和检测部分（531,541），用于检测在流动通道（33,34）中流动的各个流体的流量。 基部（41）在流动通道（33,34）之间设置有阻挡部分（57），以阻止流动通道（33,34）之间的热传导。 阻挡部（57）由形成在基座（41）上的槽（58）构成。

公开(公告)号：WO2012138604A3

公开(公告)日：2013-05-10

申请号：PCT/US2012031840

申请日：2012-04-02

Applicant: FRESENIUS MED CARE HLDG INC ,  ASH STEPHEN R ,  SULLIVAN THOMAS A ,  CARR DAVID ,  BEIRIGER MICHAEL JAMES

Inventor： ASH STEPHEN R ,  SULLIVAN THOMAS A ,  CARR DAVID ,  BEIRIGER MICHAEL JAMES

IPC: A61M1/16

CPC classification number: G01N33/0067 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/1696 ,  A61M1/305 ,  A61M1/3612 ,  A61M2205/3306 ,  A61M2205/3324 ,  A61M2230/202 ,  A61M2230/208 ,  G01N21/3504 ,  G01N33/4925 ,  G01N2033/0068 ,  Y10T436/117497 ,  Y10T436/171538 ,  Y10T436/175383 ,  Y10T436/204998

Abstract: In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.

Abstract translation: 在本发明的一个方面，一种方法包括确定使用与透析系统相关联的CO 2传感器流过透析系统的透析液中的二氧化碳（CO 2）的量，使用与透析系统相关的pH传感器测定pH 水平的透析液，以及至少部分地基于在气体中测定的CO 2的测定量和透析液的测定的pH水平来计算透析液中的碳酸氢盐水平。

公开(公告)号：WO2013025844A3

公开(公告)日：2013-05-02

申请号：PCT/US2012051011

申请日：2012-08-15

Applicant: MEDTRONIC INC ,  KELLY THOMAS D ,  LYU SUPING ,  PUDIL BRYANT J ,  MEYER THOMAS E

Inventor： KELLY THOMAS D ,  LYU SUPING ,  PUDIL BRYANT J ,  MEYER THOMAS E

IPC: A61M1/16 ,  A61M1/10 ,  A61M1/34 ,  A61M1/38

CPC classification number: A61M1/16 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/1696 ,  A61M1/3609 ,  A61M1/3612 ,  A61M2205/15 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2230/207

Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.

Abstract translation: 公开了用于执行肾脏替代疗法的装置，系统和方法，其具有或使用透析器，控制组件，吸附剂盒和流体储存器，其被配置为适于被需要治疗的个体穿戴或携带的重量和尺寸。 该系统具有受控的依从性透析电路，其中控制泵控制流体穿过透析膜的双向运动。 第一吸附剂盒被提供用于具有活性炭和氧化锆的便携式处理组件中。 该系统还提供用于监测含有脲酶的吸附剂盒的入口和出口导电性，以提供通过可拆卸的尿素去除模块量化或监测尿素去除的设施。

公开(公告)号：WO2012148781A1

公开(公告)日：2012-11-01

申请号：PCT/US2012/034303

申请日：2012-04-19

Applicant: MEDTRONIC, INC. ,  SOYKAN, Orhan ,  PUDIL, Bryant, J. ,  MEYER, Thomas, E.

Inventor： SOYKAN, Orhan ,  PUDIL, Bryant, J. ,  MEYER, Thomas, E.

IPC: A61M1/14 ,  B01D61/42

CPC classification number: B01D61/54 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/1613 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/52 ,  B01D61/246 ,  B01D61/32 ,  B01D61/422 ,  B01D61/44

Abstract: A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.

Abstract translation: 描述了用于在多种模式中操作并用于在患者血液和透析液之间维持已知梯度的钾离子或其它电解质的透析装置。 透析装置能够用于血液透析或腹膜透析，并且透析装置能够在临床环境之外的透析液净化单元或能够在临床环境中供应的水的供给下进行操作。 该透析装置具有含有用于测量患者血液和透析液中的一种或多种中的钾离子浓度的钾敏感电极的成分传感器，以及至少在以下方式调节透析液中的钾离子浓度的输液泵 部分来自组合传感器的数据。