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    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL
    11.
    发明申请
    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL 审中-公开
    用于微流控应用的流量控制器组件和并行执行多项实验的系统

    公开(公告)号：WO2010107302A3

    公开(公告)日：2011-02-24

    申请号：PCT/NL2010000044

    申请日：2010-03-16

    Applicant: AVANTIUM HOLDING B V ,  BODENSTAFF EMILIO RENE ,  MOONEN ROELANDUS HENDRIKUS WILHELMUS

    Inventor： BODENSTAFF EMILIO RENE ,  MOONEN ROELANDUS HENDRIKUS WILHELMUS

    IPC: G05D7/06 ,  F15C1/04

    CPC classification number: G05D7/0694 ,  F15C1/04 ,  F16K99/0001 ,  F16K99/0021 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  Y10T137/6416

    Abstract: The invention pertains to a flow controller assembly for microfluidic applications, which flow controller assembly comprises at least one microfluidic flow controller, which microfluidic flow controller comprises: - a microfluidic chip, which microfluidic chip comprises a channel for accommodating a fluid flow, which channel runs through said microfluidic chip and has a channel inlet that is connectable to a fluid source and a channel outlet that is connectable to a further fluid conduit, - a thermal energy transmitter, which thermal energy transmitter is adapted for heating and/or cooling at least a part of the channel by producing a thermal output, thereby influencing the flow rate of fluid that is present in said channel, - a flow sensor for measuring the flow rate of a fluid running through the flow controller, said flow sensor being adapted to produce flow rate measurement data, - a data control unit, which is connected to the flow sensor by a first data connection which first data connection allows the data control unit to receive flow rate measurement data from the flow sensor, which data control unit is connected to the thermal energy transmitter by a second data connection, which second data connection allows the data control unit to influence the thermal output of the thermal energy transmitter, which data control unit comprises a data processing unit that is adapted to determine the difference between the measured flow rate and a preset desired flow rate and to regulate the thermal output of the thermal energy transmitter in order to obtain or maintain the desired flow rate.

    Abstract translation: 本发明涉及用于微流体应用的流量控制器组件，该流量控制器组件包括至少一个微流体流量控制器，该微流体流量控制器包括： - 微流体芯片，该微流体芯片包括用于容纳流体流动的通道，该通道运行 通过所述微流体芯片并且具有可连接到流体源的通道入口和可连接到另外的流体导管的通道出口， - 热能发射器，所述热能发射器适于加热和/或冷却至少一个 通过产生热输出的一部分通道，从而影响存在于所述通道中的流体的流速;流量传感器，用于测量流过流量控制器的流体的流量，所述流量传感器适于产生流量 速率测量数据， - 数据控制单元，其通过第一数据连接与第一数据连接到流量传感器 连接允许数据控制单元从流量传感器接收流量测量数据，该数据控制单元通过第二数据连接连接到热能发射器，该第二数据连接允许数据控制单元影响热输出 所述热能发射器，所述数据控制单元包括数据处理单元，所述数据处理单元适于确定所测量的流量与预设的所需流速之间的差异，并且调节所述热能发射器的热输出以获得或维持 所需流速。

    FLOW CONTROL
    12.
    发明申请
    FLOW CONTROL 审中-公开
    流量控制

    公开(公告)号：WO2010094542A2

    公开(公告)日：2010-08-26

    申请号：PCT/EP2010/051027

    申请日：2010-01-28

    Applicant: ITI SCOTLAND LIMITED ,  CHAPRON, Julien

    Inventor： CHAPRON, Julien

    IPC: G05D7/06

    CPC classification number: G05D7/0694

    Abstract: Provided is a flow control element for a microfluidic or nanofluidic device, comprising: a) a fluid source; and b) a flow restriction component; wherein the flow restriction component is situated downstream from the fluid source, and the flow restriction component has a hydrodynamic resistance at least 5 times higher than the hydrodynamic resistance of the device. Also provided is an apparatus comprising at least one flow control element and further comprising a microfluidic or nanofluidic device. Additionally provided is the use of the flow control element or apparatus. Further provided is a method of regulating the flow rate of a fluid entering or within a microfluidic or nanofluidic device, which method comprises altering the pressure applied to a fluid within a fluid source of a flow control element or apparatus as defined in any preceding claim.

    Abstract translation: 提供了一种用于微流体或纳流体装置的流量控制元件，包括：a）流体源; 和b）流量限制部件; 其中所述流动限制部件位于所述流体源的下游，并且所述流动限制部件具有比所述装置的流体动力学阻力高至少5倍的流体动力电阻。 还提供了一种包括至少一个流量控制元件并且还包括微流体或纳流体装置的装置。 另外提供了流量控制元件或装置的使用。 进一步提供了一种调节进入或流入微流体或纳流体装置内的流体的流量的方法，该方法包括改变施加到如前述权利要求中任一项所述的流量控制元件或装置的流体源内的流体的压力。

    MICROFLUIDIC MIXING USING FLOW PULSING
    17.
    发明申请
    MICROFLUIDIC MIXING USING FLOW PULSING 审中-公开
    使用流动脉冲的微流控混合

    公开(公告)号：WO2004098757A2

    公开(公告)日：2004-11-18

    申请号：PCT/US2004/014287

    申请日：2004-05-06

    Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGY ,  AUBRY, Nadine, N. ,  GLASGOW, Ian, K.

    Inventor： AUBRY, Nadine, N. ,  GLASGOW, Ian, K.

    IPC: B01F

    CPC classification number: G05D7/0694 ,  G05D11/132 ,  Y10T137/2185

    Abstract: A method of mixing two or more fluids comprising pulsing the flow of two fluids selected from the two or more fluids, reversing the flow of one of the pulsed fluid, bringing into contact the fluids and causing them to mix. A device for mixing the fluids is also provided.

    Abstract translation: 一种混合两种或更多种流体的方法，包括使选自两种或更多种流体的两种流体的流动脉冲，使脉冲流体中的一种流动的流动反向，使其与流体接触并使它们混合。 还提供了用于混合流体的装置。

    THERMALLY ACTUATED MICROVALVE ASSEMBLY
    19.
    发明申请
    THERMALLY ACTUATED MICROVALVE ASSEMBLY 审中-公开
    热致动微型组件

    公开(公告)号：WO01071226A2

    公开(公告)日：2001-09-27

    申请号：PCT/US2001/008403

    申请日：2001-03-16

    IPC: B81B3/00 ,  B60T8/36 ,  B60T8/42 ,  B60T8/48 ,  F15B13/04 ,  F15B13/042 ,  F15B13/043 ,  F15C4/00 ,  F15C5/00 ,  F16K7/00 ,  F16K31/12 ,  F16K99/00 ,  G05D7/06 ,  F16K

    CPC classification number: F16K99/0001 ,  B60T8/366 ,  B60T8/3695 ,  B60T8/42 ,  B60T8/4275 ,  F15B13/0402 ,  F15B13/0438 ,  F15C5/00 ,  F16K99/0011 ,  F16K99/0059 ,  F16K2099/0076 ,  G05D7/0694 ,  Y10T137/86622 ,  Y10T137/86847 ,  Y10T137/87209

    Abstract: A microvalve device for controlling fluid flow in a fluid circuit (10). The microvalve device comprises a body (12) having a cavity formed therein. The body further has first (20) and second (22) pilot ports placed in fluid communication with the cavity. The body also has first (28) and second (30) primary ports placed in fluid communication with the cavity. Each port is adapted for connection with a designated fluid source. A pilot valve (36) supported by the body is movably disposed in the cavity for opening and closing the first and second pilot ports. An actuator (38) is operably coupled to the pilot valve for moving the pilot valve. A microvalve (40) is positioned by the fluid controlled by the pilot valve. The microvalve is a slider valve having a first end (40a) and a second end (40b). The slider valve is movably disposed in the cavity for movement between a first position and a second position. The first end of the slider valve is in fluid communication with the first and second pilot ports when the first and second pilot ports are open. The second end of the slider valve is in constant fluid communication with the first primary port. When moving between the first and second positions, the slider valve at least partially blocks and unblocks the second primary port for the purpose of variably restricting fluid flow between the primary ports.

    Abstract translation: 一种用于控制流体回路（10）中的流体流动的微型阀装置。 微型阀装置包括其中形成有腔的主体（12）。 主体还具有与空腔流体连通的第一（20）和第二（22）导向口。 主体还具有与腔体流体连通的第一（28）和第二（30）主端口。 每个端口适于与指定的流体源连接。 由主体支撑的先导阀（36）可移动地设置在空腔中，用于打开和关闭第一和第二先导端口。 致动器（38）可操作地联接到先导阀以用于移动先导阀。 微阀（40）由通过先导阀控制的流体定位。 微型阀是具有第一端（40a）和第二端（40b）的滑阀。 滑动阀可移动地设置在空腔中，用于在第一位置和第二位置之间移动。 当第一和第二导向口打开时，滑阀的第一端与第一和第二导向口流体连通。 滑阀的第二端与第一主端口恒定流体连通。 当在第一位置和第二位置之间移动时，为了可变地限制主端口之间的流体流动，滑块阀至少部分地阻塞和解锁第二主端口。

    HANDHELD FLUID HANDLING SYSTEMS AND METHODS
    20.
    发明申请
    HANDHELD FLUID HANDLING SYSTEMS AND METHODS 审中-公开
    手动流体处理系统和方法

    公开(公告)号：WO2015148808A1

    公开(公告)日：2015-10-01

    申请号：PCT/US2015/022761

    申请日：2015-03-26

    Applicant: LI, Zhenyu ,  LI, Baichen

    Inventor： LI, Zhenyu ,  LI, Baichen

    IPC: G01N35/10 ,  C12M1/36 ,  G05D11/02

    CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2200/146 ,  B01L2200/16 ,  B01L2300/024 ,  B01L2300/123 ,  B01L2300/14 ,  B01L2400/0487 ,  B01L2400/0666 ,  F04B43/043 ,  G01N15/1484 ,  G01N35/00871 ,  G01N2035/00237 ,  G01N2035/1034 ,  G05D7/0694 ,  G05D16/2013 ,  G05D16/2026

    Abstract: A handheld system includes a reference pressure source configured to generate a reference pressure. The handheld system also includes a primary pressure source coupled to the reference pressure source. The primary pressure source is configured to generate a primary pressure in a primary pressure range. The primary pressure is less than the reference pressure, and the primary pressure is induced by the reference pressure source. The handheld system also includes a secondary pressure source coupled to the primary pressure source. The secondary pressure source is configured to generate a secondary pressure in a secondary pressure range. The secondary pressure is less than the primary pressure, and the secondary pressure is induced by the primary pressure source.

    Abstract translation: 手持式系统包括被配置为产生参考压力的参考压力源。 手持系统还包括耦合到参考压力源的主压力源。 主压力源被配置为产生主压力范围内的主压力。 初级压力小于参考压力，初级压力由参考压力源引起。 手持系统还包括耦合到主压力源的次级压力源。 次级压力源构造成在次级压力范围内产生次级压力。 二次压力小于一次压力，二次压力由一次压力源引起。

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