摘要:
A microfluidic device can include an upstream passage, a sample passage, a bifurcating passage, and a combining passage. The upstream passage can be configured to provide a focusing stream. The sample passage can be configured to provide a sample stream. The bifurcating passage can include a specified bifurcating flow resistance. The combining passage can be configured to create a combined stream from the focusing stream and the sample stream, where the focusing stream can direct the sample stream away from the upstream passage and toward the bifurcating passage. A first portion of the combined stream can be discharged through the bifurcating passage. The main discharge can be configured to discharge a second portion of the combined stream. The main discharge can include a main discharge resistance that is selectable to vary the main discharge resistance relative to the bifurcating flow resistance.
摘要:
A microfluidic optoelectronic tweezers (OET) device can comprise dielectrophoresis (DEP) electrodes that can be activated and deactivated by controlling a beam of light directed onto photosensitive elements that are disposed in locations that are spaced apart from the DEP electrodes. The photosensitive elements can be photodiodes, which can switch the switch mechanisms that connect the DEP electrodes to a power electrode between an off state and an on state.
摘要:
Die Erfindung bezieht sich auf ein Flüssigkeits-Anaiysegerät (10) mit einem Basssgerät (12) und einem separaten austauschbaren Fiuidikmodul (14), mit einer zweigeteilten mikrofluidischen Flüssigkeits-Membranpumpe (20, 21, 22; 80). Das Flüssigkeits-Anaiysegerät (10) weist eine Pumpenkammer (34) und eine Pumpmembran (54) mit einem mit der Pumpmembran (54) in Wirkverbindung verbundenen ferromagnetischen Verdrängermitte! (40) auf. Die Pumpkammer (34), die Pumpmembran (54) und das Verdrängermittel (40) sind an dem Fiuidikmodul (14) vorgesehen. Es Ist ein Magneteiement (50) an der Pumpkammer (34) abgewandten Seite der Pumpmembran (54) vorgesehen, das ein veränderbares Magnetfeld erzeugt. Durch das Magnetfeld wird das Verdrängermittel (40) und die hierdurch bewegte Pumpenmembran (54) zur Erzeugung einer Pumpbewegung der Pumpmembran (54) zwischen einer Saugposition und einer Ausstoßposition bewegt, wobei das Magneteiement (50) an dem Basisgerät (12) vorgesehen ist.
摘要:
The present invention relates generally to the control of fluid flow rate and direction on a microfluidic device. In particular, the present invention provides an integrated valveless microfluidic device, where directional fluid control is controlled using off-chip remote valve switching and fluid flow rate changes are controlled using on-chip flow-rate changing fluid reservoirs. The present invention provides methods and systems for directional fluid control and control of fluid flow rate in an integrated microfluidic device which enables processes with different flow rates to be performed on one device without the need of on-chip valves.
摘要:
An implantable device (200) for delivering a therapeutic agent to a patient is provided. The device includes a reservoir (390) configured to contain a liquid comprising the therapeutic agent. The device further includes a cannula (110) in fluid communication with the reservoir. The cannula has an outlet configured to be in fluid communication with the patient. The device further includes a first electrode and a second electrode, at least one of the first electrode and the second electrode is planar. The device further includes a material in electrical communication with the first and second electrodes. A voltage applied between the first electrode and the second electrode produces gas from the material, the gas forcing the liquid to flow from the reservoir to the outlet.
摘要:
A valve apparatus includes a substrate, a main flow channel formed in the substrate, a control channel formed in the substrate such that the main flow channel and the control channel meet at a junction, a bi-phase material within the control channel, a heating element adjacent the control channel and the junction, the heating element being controllable to generate sufficient energy to cause the bi-phase material to transition from a solid phase to a liquid phase, and a pumping mechanism for forcing the bi-phase material either into or out of the junction when the bi-phase material is in the liquid phase.
摘要:
A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.
摘要:
System to measure blood coagulation related parameters comprising one first channel (6) adapted to contain a blood sample; said system containing, at least partially, an expandable material which is able to increase its volume when activated by an exciting source; said system furthermore comprising several excitable regions distributed close to said first channel (6), in such a way that, when one of said excitable region is activated, said expandable material increases to such an extend that the channel cross section is reduced to a location situated at or near to said excitable region.
摘要:
Microfluidic shunt valves are disclosed having a deflectable element capable of being held in a closed position to occlude the passage of fluid between an inlet and outlet and, when not held in the closed position, the deflectable element is adapted to oscillate in response to fluid pressure pulses and thereby facilitate fluid passage through the valve. Controls for activating the deflectable element to permit fluid passage are also included.
摘要:
Complex fluidic micro electromechanical systems (MEMS) are incorporated into high purity chemical delivery systems, while maintaining valve (1) sealing integrity, quality and performance of the system. In particular, fluidic MEMS systems are incorporated into high purity chemical delivery systems for semiconductor fabrication processes.