摘要:
The present disclosure relates to an oral electrolyte solution comprising lactoferrin. Lactoferrin may promote intestinal healing during a bout of diarrhea in a pediatric subject, thereby reducing the duration of diarrhea symptoms. Additionally, the oral electrolyte solutions disclosed herein may comprise Lactobacillus rhamnosus GG, vitamin B 3 and/or a source of zinc. The disclosure further relates to methods of reducing the duration of diarrhea symptoms and reducing gastrointestinal irritation in a pediatric subject by providing an oral electrolyte solution comprising lactoferrin.
摘要:
The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.
摘要:
Provided herein are methods for identifying a neurogenesis-modulating compound, comprising: culturing adipose-derived stem cells (ADSCs) in the presence of a candidate compound; and determining the extent of neurogenesis in the ADSCs and systems for identifying a neurogenesis modulating compound. Also provided are methods of promoting neurogenesis in ADSCs.
摘要:
The present disclosure generally provides nutritional compositions that are useful for promoting beneficial bacteria in the gastrointestinal tract of a Cesarean-section (C-section)-delivered infant. The nutritional composition can include a prebiotic composition comprising human milk oligosaccharides (HMO), milk fat globule membrane (MFGM), and galacto-oligosaccharides (GOS) and/or polydextrose (PDX). The present disclosure also provides methods for promoting the growth of beneficial microbiota in the gastrointestinal tract of C-section-delivered infants comprising administering to a C-section-delivered infant the disclosed nutritional composition.
摘要:
A container for particulate material includes a can end including a recessed concavity integrally formed in the can end and open to an inner chamber of the container. An absorptive material is disposed in the concavity. The absorptive material may absorb oxygen, moisture vapor, or both. At least one barrier layer is disposed between the concavity and the chamber.
摘要:
A method for enhancing neurological health and development in a subject involving administering to the subject a nutritional composition including no greater than about 7 g/100 kcal of a fat or lipid source; no greater than about 7 g/100 kcal of a protein or protein equivalent source; at least about 5 g/100 kcal of a carbohydrate; and at least about 9 mg/100 kcal of inositol, wherein the ratio of exogenous inositol to inherent inositol is at least 50:50.
摘要:
Provided is a composition and method for modulating serotonergic receptor expression, reducing anxiety-like behavior and stress-induced inflammatory response in a pediatric subject, the method including administering to the pediatric subject a nutritional composition including lactoferrin from a non-human source and a prebiotic composition including polydextrose and/or galactooligosaccharides. Further provided is a method for reducing constipation in a pediatric subject by providing a nutritional composition including lactoferrin from a non-human source and a prebiotic composition including polydextrose and/or galactooligosaccharides.
摘要:
A composition and method for enhancing brain development in a pediatric subject, the method including administering to the pediatric subject a nutritional composition comprising at least about 0.08 g/100 kcal of stearidonic acid.
摘要:
An ingestible composition including a probiotic contained in a mixture of a phospholipid and a glyceride, useful for nutrition of infants and children.
摘要:
The present disclosure provides a nutritional composition, such as a preterm infant formula that includes a protein source comprising whey protein and hydrolyzed casein protein. The whey protein to hydrolyzed casein ratio may be from about 90:10 to about 50:50 by weight. The hydrolyzed casein may have a degree of hydrolysis of from about 20% to about 80%. Additionally, provided are methods for improved gastric emptying and improved digestibility in a target subject, such as a preterm infant. When administered, the nutritional compositions may promote intestinal transit and absorptive capacity. Consequently, better growth and development, especially neurological development of the target subject may be achieved.