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    APPARATUS AND METHOD FOR MEASURING SURFACE TOPOGRAPHY OPTICALLY
    72.
    发明申请
    APPARATUS AND METHOD FOR MEASURING SURFACE TOPOGRAPHY OPTICALLY 审中-公开
    光学测量表面形貌的装置和方法

    公开(公告)号：WO2016001840A1

    公开(公告)日：2016-01-07

    申请号：PCT/IB2015/054910

    申请日：2015-06-30

    申请人： ALIGN TECHNOLOGY, INC.

    发明人： ATIYA, Yossef ,  VERKER, Tal

    IPC分类号： G01B11/24 ,  A61C9/00

    CPC分类号： A61C9/0066 ,  A61B1/00009 ,  A61B1/00011 ,  A61B1/00045 ,  A61B1/0676 ,  A61B1/247 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0088 ,  A61B5/7228 ,  A61B2562/0233 ,  A61C1/088 ,  A61C9/0046 ,  A61C9/0053 ,  G01B11/24 ,  G01B11/30

    摘要： An apparatus is described for determining surface topography of a three-dimensional structure. The apparatus can include a probe (90) and an illumination unit (28,32,34,38) configured to output a plurality of light beams (36). In many embodiments, the apparatus includes a light focusing assembly (42,44). The light focusing assembly can receive and focus each of a plurality of light beams to a respective external focal point. The light focusing assembly can be configured to overlap the plurality of light beams within a focus changing assembly (224,234) in order to move the external focal points along a direction of propagation of the light beams. The apparatus can include a detector (60) having an array of sensing elements configured to measure a characteristic of each of a plurality of light beams returning from the illuminated spots and a processor (24) coupled to the detector and configured to generate data representative of topography of the structure based on the measured characteristic.

    摘要翻译： 描述了一种用于确定三维结构的表面形貌的装置。 该装置可以包括被配置为输出多个光束（36）的探针（90）和照明单元（28,32,34,38）。 在许多实施例中，该装置包括光聚焦组件（42,44）。 光聚焦组件可以将多个光束中的每一个接收并聚焦到相应的外部焦点。 光聚焦组件可以被配置为与聚焦改变组件（224,234）内的多个光束重叠，以便沿着光束的传播方向移动外部焦点。 该装置可以包括检测器（60），其具有被配置成测量从照明点返回的多个光束中的每一个的特性的感测元件的阵列;以及耦合到检测器的处理器（24），并且被配置为产生代表 基于测量特征的结构地形。

    A METHOD FOR DIAGNOSING BIRTHMARKS ON THE SKIN
    73.
    发明申请
    A METHOD FOR DIAGNOSING BIRTHMARKS ON THE SKIN 审中-公开
    用于诊断皮肤上生物标记的方法

    公开(公告)号：WO2015199560A1

    公开(公告)日：2015-12-30

    申请号：PCT/PL2014/000086

    申请日：2014-07-24

    申请人： KTG SP. Z O.O.

    发明人： GROCHOWINA, Marcin

    IPC分类号： A61B5/00

    CPC分类号： A61B5/444 ,  A61B5/0013 ,  A61B5/0077 ,  A61B5/4842 ,  A61B5/7246 ,  A61B2576/02

    摘要： A method of diagnosing birthmarks on the skin with the use of the microprocessor diagnostic system characterized in that the image of skin area recorded by a camera (1) is transmitted to the microprocessor diagnostic system (2), and implemented in its interior algorithms executed by the microprocessor perform image analysis in order to obtain diagnostic information, wherein at first area subjected to testing is typed (3) within which the birthmarks are detected (4), then the coordinates of the birthmarks are determined and they are counted (5) and compared (6) with previous records of the same skin area stored in the database (8), giving the result (7) constituting the material, which is determining the growth of the amount of birthmarks and its dynamics on a given area of the skin.

    摘要翻译： 一种使用微处理器诊断系统来诊断皮肤上的胎记的方法，其特征在于由照相机（1）记录的皮肤区域的图像被传送到微处理器诊断系统（2），并且在其内部算法中实现 微处理器执行图像分析以获得诊断信息，其中在第一区域进行测试（3），其中检测到胎记（4），然后确定胎记的坐标，并对它们进行计数（5）和 将（6）与存储在数据库中的相同皮肤区域的先前记录（8）进行比较，给出构成材料的结果（7），该结果确定胎儿的给定面积上胎记数量及其动力学的增长 。

    HIGH-RESOLUTION METABOLIC NEUROIMAGING
    76.
    发明申请
    HIGH-RESOLUTION METABOLIC NEUROIMAGING 审中-公开
    高分辨率代谢神经元

    公开(公告)号：WO2015073957A1

    公开(公告)日：2015-05-21

    申请号：PCT/US2014/065924

    申请日：2014-11-17

    申请人： ROONEY, William ,  SPRINGER, Charles ,  LI, Xin ,  OREGON HEALTH & SCIENCE UNIVERSITY

    发明人： ROONEY, William ,  SPRINGER, Charles ,  LI, Xin

    IPC分类号： A61B5/055

    CPC分类号： A61B5/0263 ,  A61B5/0013 ,  A61B5/0037 ,  A61B5/0295 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4082 ,  A61B5/4088 ,  A61B5/4866 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/748 ,  G01R33/4828 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/56366

    摘要： Provided herein are methods and apparatuses for determining a level of cellular metabolic activity for a region of interest in order to detect and map on-going gliovascular unit metabolic activity using high-resolution 1H2O MRI. In one example approach, a computer-implemented method includes receiving a first set of DCE-MRI time-course data for a region, wherein a contrast agent is administered prior to imaging, identifying a region of interest from the first set of DCE-MRI time-course data for further analysis, performing shutter-speed pharmacokinetic analysis of the time-course data associated with the region of interest using computer-implemented software to obtain a finite and non-zero mean water molecule capillary lifetime in the region of interest, and indicating a level of cellular metabolic activity in the brain based on the mean water molecule capillary lifetime.

    摘要翻译： 本文提供了用于确定感兴趣区域的细胞代谢活动水平的方法和装置，以便使用高分辨率1H2O MRI来检测和映射正在进行的心血管单位代谢活动。 在一个示例性方法中，计算机实现的方法包括接收用于区域的第一组DCE-MRI时间段数据，其中在成像之前施用造影剂，从第一组DCE-MRI识别感兴趣区域 用于进一步分析的时间过程数据，使用计算机实现的软件执行与感兴趣区域相关联的时间线数据的快门速度药代动力学分析，以获得感兴趣区域中的有限和非零平均水分子毛细管寿命， 并基于平均水分子毛细管寿命指示脑中的细胞代谢活性水平。

    DIAGNOSTIC DEVICE FOR DERMATOLOGY WITH MERGED OCT AND EPILUMINESCENCE DERMOSCOPY
    77.
    发明申请
    DIAGNOSTIC DEVICE FOR DERMATOLOGY WITH MERGED OCT AND EPILUMINESCENCE DERMOSCOPY 审中-公开
    具有合并OCT和透明性皮肤病的诊断装置

    公开(公告)号：WO2015063313A1

    公开(公告)日：2015-05-07

    申请号：PCT/EP2014/073644

    申请日：2014-11-04

    申请人： DERMALUMICS S.L.

    发明人： BARRIGA RIVERA, Alejandro ,  RUBIO GUIVERNAU, José Luis ,  MARGALLO BALBÁS, Eduardo

    IPC分类号： A61B5/00

    CPC分类号： A61B5/444 ,  A61B5/0013 ,  A61B5/0017 ,  A61B5/0022 ,  A61B5/0035 ,  A61B5/0066 ,  A61B5/0077 ,  A61B5/7246 ,  A61B5/7425 ,  A61B2576/02 ,  G01B9/02091 ,  G06F19/00 ,  G16H40/67

    摘要： Systems and methods for use of the imaging system are presented. In an embodiment, the imaging system includes a first optical path, a second optical path, a plurality of optical elements, a detector, and a processor. The first optical path guides a first beam of radiation associated with epiluminescence while the second optical path guides a second beam of radiation associated with optical coherence tomography. The plurality of optical elements transmit the first and second beams of radiation onto a sample. The detector generates optical data associated with the first and second beams of radiation returning from the sample. The optical data associated with the first and second beams of radiation correspond to substantially non-coplanar regions of the sample. The processor correlates the optical data of the first beam with the optical data of the second beam and generates an image of the sample.

    摘要翻译： 介绍了使用成像系统的系统和方法。 在一个实施例中，成像系统包括第一光路，第二光路，多个光学元件，检测器和处理器。 第一光路引导与外发光相关联的第一辐射束，而第二光路引导与光学相干断层摄影相关联的第二辐射束。 多个光学元件将第一和第二辐射束发射到样品上。 检测器产生与从样品返回的第一和第二辐射束相关联的光学数据。 与第一和第二辐射束相关联的光学数据对应于样品的基本非共面区域。 处理器将第一光束的光学数据与第二光束的光学数据相关联，并生成样本的图像。

    DETECTION OF A LEADING STROKE RISK INDICATOR
    80.
    发明申请
    DETECTION OF A LEADING STROKE RISK INDICATOR 审中-公开
    检测引导风险指标

    公开(公告)号：WO2014209303A1

    公开(公告)日：2014-12-31

    申请号：PCT/US2013/047947

    申请日：2013-06-26

    申请人： INTEL CORPORATION

    发明人： THOMPSON, Jonathan

    IPC分类号： A61B5/02

    CPC分类号： A61B5/7246 ,  A61B5/0013 ,  A61B5/004 ,  A61B5/02007 ,  A61B5/7235 ,  A61B5/7275 ,  A61B5/7282 ,  G06F19/00

    摘要： Embodiments of a system and method for detecting a leading stroke risk indicator using low-cost, non-contact visual computing methods are generally described herein. In some embodiments, a video camera is arranged to capture a video of a face of a subject to be evaluated for having a stroke risk indicator. A memory is provided for storing data. A processor is coupled to the memory and is arranged to analyze processed image data associated with the video of the face of the subject captured by the video camera. The processor is further arranged to determine whether the processed image data exhibits a leading indicator for carotid artery stenosis.

    摘要翻译： 本文通常描述使用低成本，非接触式视觉计算方法来检测引导笔划风险指标的系统和方法的实施例。 在一些实施例中，摄像机布置成捕获要评估的对象的脸部的视频以具有行程风险指示符。 提供用于存储数据的存储器。 处理器耦合到存储器并且被布置成分析与由摄像机捕获的被摄体的面部的视频相关联的经处理的图像数据。 处理器还被布置成确定处理的图像数据是否表现出颈动脉狭窄的前导指示符。