-
公开(公告)号：WO2013090693A1
公开(公告)日：2013-06-20
申请号：PCT/US2012/069703
申请日：2012-12-14
Applicant: SEMPRUS BIOSCIENCES CORP. , WEAVER, Douglas , ZHANG, Zheng , LI, Jun , SKINNER, Matt , ROTH, Laurence , BOUCHARD, Michael , MARCHESE, Eric W. , DELEAULT, Abby N. , MILLER, Abbe , HUVAL, Chad , LOOSE, Christopher R. , COURY, Arthur J.
Inventor： WEAVER, Douglas , ZHANG, Zheng , LI, Jun , SKINNER, Matt , ROTH, Laurence , BOUCHARD, Michael , MARCHESE, Eric W. , DELEAULT, Abby N. , MILLER, Abbe , HUVAL, Chad , LOOSE, Christopher R. , COURY, Arthur J.
CPC classification number: A61M25/0021 , A61L29/085 , A61L29/14 , A61M25/00 , A61M25/0009 , A61M25/0043 , A61M2025/0019 , A61M2025/0047 , B05D7/22 , B05D7/24 , Y10T428/1352 , Y10T428/1393 , C08L33/14
Abstract: Catheters and a method of preparation thereof comprising a catheter body and at least one connector. The catheter body has an exterior surface and at least one lumen having an aspect ratio of at least 3:1 and an intraluminal surface comprising a hydrophilic polymer layer thereon, the hydrophilic polymer layer has an average dry thickness of at least about 50 nanometers.
Abstract translation: 导管及其制备方法，其包括导管主体和至少一个连接器。 导管体具有外表面和至少一个具有至少3:1的纵横比的内腔和其上包含亲水性聚合物层的管腔内表面，亲水性聚合物层具有至少约50纳米的平均干厚度。
-
2.发明申请
公开(公告)号：WO2011156589A3
公开(公告)日：2012-04-26
申请号：PCT/US2011039790
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP , LI JUN , ZHANG ZHENG , HUVAL CHAD , BOUCHARD MICHAEL , COURY ARTHUR J , LOOSE CHRISTOPHER R
Inventor： LI JUN , ZHANG ZHENG , HUVAL CHAD , BOUCHARD MICHAEL , COURY ARTHUR J , LOOSE CHRISTOPHER R
CPC classification number: C08F255/02 , A61L29/06 , A61L29/085 , A61L33/0088 , C08F291/00 , C08G18/836 , C08G64/42 , C08G77/38 , C08J7/16 , C08J7/18 , C08J2323/12 , C08J2369/00 , C08J2383/04 , C08J2433/14 , Y10T428/24355 , Y10T428/265 , Y10T442/30 , Y10T442/60 , C08F220/00
Abstract: A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37 C in 70 µg/mL fibrinogen derived from human plasma containing 1.4 µg/mL I-125 radiolabeled fibrinogen.
Abstract translation: 一种用于制备和产生的制品的方法，包括具有表面，表面下面的体积的基材和在基材表面上的接枝聚合物层，基底表面和接枝聚合物层的组合，构成具有 在纤维蛋白原结合测定中，纤维蛋白原吸附小于约125ng / cm 2，其中将修饰的表面在37℃下在来自含有1.4μg/ mL I-125放射性标记的纤维蛋白原的人血浆的70μg/ mL纤维蛋白原中温育60分钟。
-
3.发明申请ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING APPLYING A PRIMER COAT 审中-公开具有非浮选表面的制品及其制备方法，包括适用于底漆
公开(公告)号：WO2011156612A2
公开(公告)日：2011-12-15
申请号：PCT/US2011/039815
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP. , SCHULTZ, Karen Ann , ZHANG, Zheng , HUVAL, Chad C. , BOUCHARD, Michael A. , LOOSE, Christopher R.
Inventor： SCHULTZ, Karen Ann , ZHANG, Zheng , HUVAL, Chad C. , BOUCHARD, Michael A. , LOOSE, Christopher R.
CPC classification number: A61L33/0088 , A61L33/027 , B05D3/10 , B05D7/54 , C09D5/1693 , Y10T428/24802 , Y10T428/25 , Y10T428/31504 , Y10T428/31551 , Y10T428/31609
Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve coating the substrate to conceal or reduce flaws on or in the surface of the medical device or other article substrate, and thereafter forming a grafted polymer layer on the treated substrate surface
Abstract translation: 本文描述了用于制备在包括聚合物表面的基底上具有低污损表面的医疗装置和其它制品的方法。 聚合物表面材料可以具有一定范围的聚合物主链和取代基，同时为制品提供高效，生物相容性和非结垢性表面。 该方法包括涂覆基底以隐藏或减少医疗装置或其它制品基底表面上或其表面上的缺陷，然后在经处理的基底表面上形成接枝聚合物层
-
4.发明申请ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING PRETREATMENT OF SUBSTRATES 审中-公开具有非浮选表面的制品及其制备方法，包括底材预处理
公开(公告)号：WO2011156596A2
公开(公告)日：2011-12-15
申请号：PCT/US2011/039799
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP. , ROTH, Laurence A. , ZHANG, Zheng , HUVAL, Chad C. , BOUCHARD, Michael A. , LOOSE, Christopher R.
Inventor： ROTH, Laurence A. , ZHANG, Zheng , HUVAL, Chad C. , BOUCHARD, Michael A. , LOOSE, Christopher R.
CPC classification number: A61L33/0088 , A61L33/027 , B05D3/10 , B05D7/54 , C09D5/1693 , Y10T428/24802 , Y10T428/25 , Y10T428/31504 , Y10T428/31551 , Y10T428/31609
Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface
Abstract translation: 本文描述了用于制备在包括聚合物表面的基底上具有低污损表面的医疗装置和其它制品的方法。 聚合物表面材料可以具有一定范围的聚合物主链和取代基，同时为制品提供高效，生物相容性和非结垢性表面。 该方法包括处理底物以降低基材表面上或在基材中的化学物质的浓度，而不改变装置或制品的体积物理性能，然后在经处理的基材表面上形成接枝聚合物层
-
公开(公告)号：WO2011156590A3
公开(公告)日：2011-12-15
申请号：PCT/US2011/039792
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP. , ZHANG, Zheng , LI, Jun , HUVAL, Chad , BOUCHARD, Michael , COURY, Arthur, J. , LOOSE, Christopher, R.
Inventor： ZHANG, Zheng , LI, Jun , HUVAL, Chad , BOUCHARD, Michael , COURY, Arthur, J. , LOOSE, Christopher, R.
Abstract: The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material.
-
Patent Agency Ranking
公开(公告)号：WO2011156590A2
公开(公告)日：2011-12-15
申请号：PCT/US2011039792
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP , ZHANG ZHENG , LI JUN , HUVAL CHAD , BOUCHARD MICHAEL , COURY ARTHUR J , LOOSE CHRISTOPHER R
Inventor： ZHANG ZHENG , LI JUN , HUVAL CHAD , BOUCHARD MICHAEL , COURY ARTHUR J , LOOSE CHRISTOPHER R
CPC classification number: A61L31/10 , A61L27/34 , A61L27/54 , A61L31/16 , A61L33/0029 , A61L2300/252 , A61L2300/404 , A61L2300/42 , A61L2300/606 , A61L2420/02 , B32B5/022 , B32B5/024 , B32B5/16 , B32B5/26 , B32B5/30 , B32B9/00 , B32B9/005 , B32B9/04 , B32B9/041 , B32B9/043 , B32B9/047 , B32B9/048 , B32B15/04 , B32B15/043 , B32B15/08 , B32B15/14 , B32B15/16 , B32B27/08 , B32B27/12 , B32B27/14 , B32B27/28 , B32B27/281 , B32B27/283 , B32B27/285 , B32B27/286 , B32B27/288 , B32B27/34 , B32B27/36 , B32B27/365 , B32B27/38 , B32B27/40 , B32B2255/10 , B32B2255/26 , B32B2307/538 , B32B2307/7145 , B32B2307/732 , B32B2535/00 , Y10T428/24364 , Y10T428/26 , Y10T428/265 , Y10T428/2962 , Y10T428/31504 , Y10T428/31551 , Y10T428/31598 , Y10T428/31612 , Y10T428/31663 , Y10T428/31678 , Y10T428/31855 , Y10T442/30 , Y10T442/60
Abstract: The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material
Abstract translation: 本发明一般涉及具有包含接枝聚合物材料的非结垢表面的制品，例如医疗装置。 表面抗生物材料的粘附
-
公开(公告)号：WO2016196694A1
公开(公告)日：2016-12-08
申请号：PCT/US2016/035361
申请日：2016-06-01
Applicant: MILLER, Benjamin, Aaron , JUSTMAN, Jason, D. , BOUCHARD, Lora, Clark , BOUCHARD, Michael, Ellery , COTLOVE, Kevin, James , GITCHELL, Matthew, Keith , HAISCH, Stacia, Lynn , KERSTEN, Jonathan, David , MARCHIO, Matthew, Karl , PULLIAM, Peter, Arthur , SMITH, George, Allen , TIBBETTS, Todd, Christopher
Inventor： MILLER, Benjamin, Aaron , JUSTMAN, Jason, D. , BOUCHARD, Lora, Clark , BOUCHARD, Michael, Ellery , COTLOVE, Kevin, James , GITCHELL, Matthew, Keith , HAISCH, Stacia, Lynn , KERSTEN, Jonathan, David , MARCHIO, Matthew, Karl , PULLIAM, Peter, Arthur , SMITH, George, Allen , TIBBETTS, Todd, Christopher
IPC: G06F17/00
CPC classification number: G06F17/30058
Abstract: Techniques are described herein for optimizing the presentation of content through obtaining viewership metrics, generating multiple renditions of presentations of content, and selecting optimized renditions of content. One aspect includes associating a request for viewership metrics with a presentation of content, publishing the presentation of content, and receiving information of the viewership metrics associated with the presentation. Another aspect includes copying a presentation of a content item, creating a second presentation of the content item for publishing over one or more channels, and linking the presentation of the content item to the second presentation of the content item, such that a change to one propagates to the other of the presentation of the content item or the second presentation of the content item. In yet another aspect, a content rendition may be selected for presentation based on performance of the rendition out of multiple renditions in an auction.
Abstract translation: 本文描述了通过获得观看度量来优化内容呈现，生成多个呈现内容的呈现以及选择优化的内容再现的技术。 一方面包括将观众指标的请求与呈现内容相关联，发布内容呈现以及接收与呈现相关联的观众度量度量的信息。 另一方面包括复制内容项目的呈现，创建用于在一个或多个频道上发布的内容项目的第二呈现，以及将内容项目的呈现链接到内容项目的第二呈现，使得改变为一个 传播到内容项目的呈现或内容项目的第二呈现中的另一个。 在另一方面，可以基于在拍卖中的多个再现中的演绎的性能来选择内容再现来呈现。
-
8.发明申请ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME WITHOUT ALTERING BULK PHYSICAL PROPERTIES 审中-公开具有非浮选表面的制品及其制备方法，不改变物理性质
公开(公告)号：WO2011156603A3
公开(公告)日：2012-04-26
申请号：PCT/US2011039806
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP , WEAVER DOUGLAS J K , LI JUN , ZHANG ZHENG , DELEAULT ABBY N , MARCHESE ERIC W , NGUYEN PHU C , HUVAL CHAD C , BOUCHARD MICHAEL A , COURY ARTHUR J , LOOSE CHRISTOPHER R
Inventor： WEAVER DOUGLAS J K , LI JUN , ZHANG ZHENG , DELEAULT ABBY N , MARCHESE ERIC W , NGUYEN PHU C , HUVAL CHAD C , BOUCHARD MICHAEL A , COURY ARTHUR J , LOOSE CHRISTOPHER R
CPC classification number: A61L33/0088 , A61L33/027 , B05D3/10 , B05D7/54 , C09D5/1693 , Y10T428/24802 , Y10T428/25 , Y10T428/31504 , Y10T428/31551 , Y10T428/31609
Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface
Abstract translation: 本文描述了用于制备在包括聚合物表面的基底上具有低污损表面的医疗装置和其它制品的方法。 聚合物表面材料可以具有一定范围的聚合物主链和取代基，同时为制品提供高效，生物相容性和非结垢性表面。 该方法包括处理底物以降低基材表面上或在基材中的化学物质的浓度，而不改变装置或制品的体积物理性能，然后在经处理的基材表面上形成接枝聚合物层
-
9.发明申请ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME INCLUDING PRETREATMENT OF SUBSTRATES 审中-公开具有非污染表面的制品及其制备方法，包括预处理基质
公开(公告)号：WO2011156596A3
公开(公告)日：2012-04-26
申请号：PCT/US2011039799
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP , ROTH LAURENCE A , ZHANG ZHENG , HUVAL CHAD C , BOUCHARD MICHAEL A , LOOSE CHRISTOPHER R
Inventor： ROTH LAURENCE A , ZHANG ZHENG , HUVAL CHAD C , BOUCHARD MICHAEL A , LOOSE CHRISTOPHER R
CPC classification number: A61L33/0088 , A61L33/027 , B05D3/10 , B05D7/54 , C09D5/1693 , Y10T428/24802 , Y10T428/25 , Y10T428/31504 , Y10T428/31551 , Y10T428/31609
Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface.
Abstract translation: 本文描述了用于制备在包含聚合物表面的基底上具有低污垢表面的医疗装置和其他制品的方法。 聚合物表面材料可具有一定范围的聚合物主链和取代基，同时为制品提供高效，生物相容且不结垢的表面。 该方法涉及处理基材以降低基材表面上或基材中的化学物质的浓度，而不改变装置或制品的整体物理性质，并且此后在处理过的基材表面上形成接枝聚合物层。
-
10.发明申请ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME WITHOUT ALTERING BULK PHYSICAL PROPERTIES 审中-公开具有非浮选表面的制品及其制备方法，不改变物理性质
公开(公告)号：WO2011156603A2
公开(公告)日：2011-12-15
申请号：PCT/US2011039806
申请日：2011-06-09
Applicant: SEMPRUS BIOSCIENCES CORP , WEAVER DOUGLAS J K , LI JUN , ZHANG ZHENG , DELEAULT ABBY N , MARCHESE ERIC W , NGUYEN PHU C , HUVAL CHAD C , BOUCHARD MICHAEL A , COURY ARTHUR J , LOOSE CHRISTOPHER R
Inventor： WEAVER DOUGLAS J K , LI JUN , ZHANG ZHENG , DELEAULT ABBY N , MARCHESE ERIC W , NGUYEN PHU C , HUVAL CHAD C , BOUCHARD MICHAEL A , COURY ARTHUR J , LOOSE CHRISTOPHER R
CPC classification number: A61L33/0088 , A61L33/027 , B05D3/10 , B05D7/54 , C09D5/1693 , Y10T428/24802 , Y10T428/25 , Y10T428/31504 , Y10T428/31551 , Y10T428/31609
Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface
Abstract translation: 本文描述了用于制备在包括聚合物表面的基底上具有低污损表面的医疗装置和其它制品的方法。 聚合物表面材料可以具有一定范围的聚合物主链和取代基，同时为制品提供高效，生物相容性和非结垢性表面。 该方法包括处理底物以降低基材表面上或在基材中的化学物质的浓度，而不改变装置或制品的体积物理性能，然后在经处理的基材表面上形成接枝聚合物层
-
-
-
-
-
-
-
-
-
Search Results
23
records
(took 0.03 seconds)
