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公开(公告)号:WO2008134734A2
公开(公告)日:2008-11-06
申请号:PCT/US2008/062038
申请日:2008-04-30
发明人: SKAFF, Habib , BREITENKAMP, Kurt , SILL, Kevin, N.
CPC分类号: A61K49/1806 , A61K9/1075 , A61K49/1887 , B82Y5/00
摘要: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
摘要翻译: 本发明涉及聚合物化学领域,更具体地涉及封装造影剂及其使用方法。
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公开(公告)号:WO2006074202A2
公开(公告)日:2006-07-13
申请号:PCT/US2006/000144
申请日:2006-01-04
发明人: BREITENKAMP, Kurt , SILL, Kevin N.
IPC分类号: C11D17/00
CPC分类号: C08G73/0233 , C08F283/06 , C08F293/00 , C08F293/005 , C08F297/00 , C08G73/028 , C08L51/08 , C08L53/00 , C08L2666/02
摘要: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
摘要翻译: 本发明涉及聚合物化学领域,更具体地涉及多嵌段共聚物及其制备方法。
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公开(公告)号:WO2006047419A2
公开(公告)日:2006-05-04
申请号:PCT/US2005/038187
申请日:2005-10-24
发明人: BREITENKAMP, Kurt , SILL, Kevin, N. , SKAFF, Habib
IPC分类号: C07F9/113
CPC分类号: C07C323/12 , A61K47/60 , C07C67/08 , C07C67/31 , C07C69/76 , C07C69/92 , C07C205/34 , C07C213/08 , C07C247/10 , C07C271/16 , C07C319/14 , C07D207/452 , C07D209/48 , C07D213/71 , C07F7/1892 , C08G65/2612 , C08G65/2627 , C08G65/329 , C08G65/33337 , C08G65/33396 , C08L2203/02 , C07C215/08
摘要: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
摘要翻译: 本发明提供双官能聚合物,其制备方法及其中间体。 这些化合物可用于各种应用,包括生物活性分子的PEG化。 本发明还提供了使用所述化合物及其组合物的方法。
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公开(公告)号:WO2006045070A3
公开(公告)日:2006-04-27
申请号:PCT/US2005/037972
申请日:2005-10-20
摘要: Amphiphilic Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies.
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5.
公开(公告)号:WO2008134761A2
公开(公告)日:2008-11-06
申请号:PCT/US2008/062113
申请日:2008-04-30
申请人: INTEZYNE TECHNOLOGIES, INC. , BREITENKAMP, Kurt , RIOS-DORIA, Jonathan , BREITENKAMP, Rebecca , SILL, Kevin, N. , SKAFF, Habib
发明人: BREITENKAMP, Kurt , RIOS-DORIA, Jonathan , BREITENKAMP, Rebecca , SILL, Kevin, N. , SKAFF, Habib
CPC分类号: A61K47/645 , A61K47/555 , A61K47/60 , A61K47/62
摘要: The present invention relates to the field of polymer chemistry and more particularly to click- functionalized targeting compounds and methods for using the same.
摘要翻译: 本发明涉及聚合物化学领域,更具体地涉及点击功能化靶向化合物及其使用方法。
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公开(公告)号:WO2006107903A2
公开(公告)日:2006-10-12
申请号:PCT/US2006/012382
申请日:2006-04-03
申请人: INTEZYNE TECHNOLOGIES, INCORPORATED , BREITENKAMP, Kurt , SILL, Kevin , SKAFF, Habib , BREINTENKAMP, Rebecca
CPC分类号: A61K47/34 , A61K9/1075 , A61K9/19 , A61K47/551 , A61K47/62 , A61K47/6907 , C08G69/40 , C08G73/028 , C12N15/88
摘要: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
摘要翻译: 本发明涉及聚合物化学领域,更具体地涉及包含其的多嵌段共聚物和胶束。
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7.PEG-SUBSTITUTED PYRIDINE LIGANDS AND RELATED WATER-SOLUBLE CATALYSTS 审中-公开
标题翻译: PEG取代的吡啶配体和相关的水溶性催化剂公开(公告)号:WO2006045070A2
公开(公告)日:2006-04-27
申请号:PCT/US2005037972
申请日:2005-10-20
发明人: EMRICK TODD S , BREITENKAMP KURT
IPC分类号: C07F7/10
CPC分类号: C07C51/367 , C07D213/68 , C07F15/002 , C07F15/0046 , C08G61/06 , C07C59/42
摘要: Amphiphilic Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies.
摘要翻译: 两亲性VIII族复分解催化剂,可用于一系列聚合反应和其他化学方法。
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8.
公开(公告)号:WO2005025736A1
公开(公告)日:2005-03-24
申请号:PCT/US2004/028668
申请日:2004-09-03
IPC分类号: B01J13/00
CPC分类号: C08G61/08 , A61K9/5089 , B01J13/14 , C08L65/00
摘要: Polymer capsules from amphiphilic graft copolymers comprising reactive, hydrophobic polyolefin backbones, and hydrophilic poly(ethylene glycol) (PEG) grafts are produced by self-assembly of the polymers at the oilwater interface, and crosslinking the assembly with bis-cyclooctene PEG derivatives in conjunction with ring-open metathesis polymerization catalysts. The use of the graft copolymer architecture in capsule synthesis provides significant opportunities to tune both the surface properties, in terms of recognition, and the membrane properties, in terms of mechanical strength, encapsulation, and release.
摘要翻译: 包含反应性疏水性聚烯烃主链和亲水性聚(乙二醇)(PEG)接枝物的两亲性接枝共聚物的聚合物胶囊通过聚合物在油水界面处的自组装,并且将双组分与双环辛烯PEG衍生物结合 与开环易位聚合催化剂。 在胶囊合成中使用接枝共聚物结构提供了在机械强度,包封和释放方面调节表面性能方面,在识别方面以及膜性质方面的重要机会。
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9.SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS 审中-公开
标题翻译: 混合嵌段共聚物的合成从非离子表面活性剂公开(公告)号:WO2009134984A1
公开(公告)日:2009-11-05
申请号:PCT/US2009/042283
申请日:2009-04-30
IPC分类号: C08G65/333 , C08G69/02 , C08G69/08 , C08G69/14
CPC分类号: C08G65/2609 , C08G65/325 , C08G65/3322 , C08G65/3324 , C08G65/33306 , C08G65/33396 , C08G65/3346 , C08G65/337 , C08G69/02 , C08G69/08 , C08G69/14 , C08G69/40 , C08G2650/60
摘要: The present invention provides polymerization initiators and uses thereof.
摘要翻译: 本发明提供聚合引发剂及其用途。
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10.HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS 审中-公开
标题翻译: 具有混合立体化学的混合嵌段共聚物微胶囊用于渗透代谢物公开(公告)号:WO2008134731A1
公开(公告)日:2008-11-06
申请号:PCT/US2008/062033
申请日:2008-04-30
发明人: SILL, Kevin, N. , SKAFF, Habib , BREITENKAMP, Kurt
CPC分类号: C08J3/03 , A61K9/1075 , A61K47/34 , C08G65/2627 , C08G65/325 , C08G65/33341 , C08G73/028 , C08G2261/126 , C08J2377/04 , C08L2203/02 , Y10S930/29 , Y10S977/773 , Y10S977/906
摘要: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
摘要翻译: 本发明涉及聚合物化学领域,更具体地涉及包含其的多嵌段共聚物和胶束。
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