公开(公告)号：WO2012160157A1

公开(公告)日：2012-11-29

申请号：PCT/EP2012/059749

申请日：2012-05-24

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH ,  DAY, Shane Alistair

Inventor： DAY, Shane Alistair

IPC: A61M5/20 ,  A61M5/24 ,  A61M5/31 ,  A61M5/14

CPC classification number: A61M5/31546 ,  A61M5/1407 ,  A61M5/2066 ,  A61M5/2448 ,  A61M5/3146 ,  A61M5/31595 ,  A61M2005/1402 ,  A61M2005/2414 ,  A61M2005/2496

Abstract: A medicament delivery device (10) for the administration of one or more drug agents is described. The device (10) has a priming mode (920, 945) and a drug delivery mode (947) for administering delivery of the drug agents. The device includes a controller (700) operative for controlling the device (10) to perform a priming operation, and a user interface (74) for activation of the priming operation. The controller (700) is operative to perform the priming operation by way of a plurality of intermittent doses of medicament, the number of intermittent doses being dependent on the activation of the user interface (74).

Abstract translation: 描述了用于施用一种或多种药物的药物输送装置（10）。 装置（10）具有用于施用药物的递送的起动模式（920,945）和药物输送模式（947）。 该装置包括可操作用于控制装置（10）执行启动操作的控制器（700）和用于激活启动操作的用户界面（74）。 控制器（700）可操作以通过多个间歇剂量的药物进行启动操作，间歇剂量的数量取决于用户界面（74）的激活。

公开(公告)号：WO2012160156A3

公开(公告)日：2012-11-29

申请号：PCT/EP2012/059747

申请日：2012-05-24

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH ,  EGGERT, Ilona ,  LANGLEY, Christopher, Nigel ,  DAY, Shane, Alistair

Inventor： EGGERT, Ilona ,  LANGLEY, Christopher, Nigel ,  DAY, Shane, Alistair

IPC: A61M5/142 ,  A61M5/20 ,  A61M5/145 ,  A61M5/19 ,  A61M5/168

Abstract: A medicament delivery device is shown for the administration of one or more drug agents. The device has a priming mode and a drug delivery mode for administering delivery of the one or more drug agents. The device comprises a controller configured to set the device in a priming mode when one or more predetermined states of the device are identified and to disable the drug delivery mode during said predetermined state(s). When states of the device are different from said predetermined states, the controller can set the device in the drug delivery mode. A priming mode may still be enabled through a user interface.

公开(公告)号：WO2009022139A1

公开(公告)日：2009-02-19

申请号：PCT/GB2008/002750

申请日：2008-08-13

Applicant: CONSORT MEDICAL PLC ,  WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David

Inventor： WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David

IPC: A61M15/00 ,  B65D83/14 ,  G01F11/00

CPC classification number: A61M15/009 ,  A61M15/0065 ,  A61M15/0071 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0091 ,  A61M15/0093 ,  A61M16/204 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2205/276 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/52 ,  A61M2205/584 ,  A61M2205/8206 ,  B65D83/54 ,  G01F11/022 ,  G01F11/32

Abstract: A metered dose inhaler apparatus, for dispensing a metered dose of a medicinal formulation. The apparatus (200) comprises a housing (201, 202), for receiving a dispensing container (2') of medicinal formulation; a valve actuation means (206), for supplying an electrical actuation signal; and a valve actuator (204), operably-connectable to said dispensing container, for receiving the electrical actuation signal and providing actuation of said dispensing container. Wherein, the metered dose inhaler apparatus comprises dose counter means (207) operable in response to the electrical actuation signal to index the dose counter.

Abstract translation: 用于分配计量剂量的药物制剂的计量剂量吸入器装置。 装置（200）包括用于接收药物配制剂的分配容器（2'）的壳体（201,202） 用于提供电致动信号的阀致动装置（206）; 以及可操作地连接到所述分配容器的阀致动器（204），用于接收电致动信号并提供所述分配容器的致动。 其中，计量剂量吸入器装置包括剂量计数器装置（207），其响应于电致动信号而可操作以对剂量计数器进行索引。

公开(公告)号：WO2012160160A1

公开(公告)日：2012-11-29

申请号：PCT/EP2012/059752

申请日：2012-05-24

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH ,  EGGERT, Ilona ,  LANGLEY, Christopher Nigel ,  DAY, Shane Alistair

Inventor： EGGERT, Ilona ,  LANGLEY, Christopher Nigel ,  DAY, Shane Alistair

IPC: A61M5/24 ,  A61M5/20 ,  A61M5/142 ,  A61M5/34

CPC classification number: A61M5/16831 ,  A61M5/20 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/31576 ,  A61M5/34 ,  A61M2005/14268 ,  A61M2205/14 ,  A61M2205/50 ,  A61M2205/6018

Abstract: A medicament delivery device is shown for the administration of one or more drug agents. The device comprises a medicament cartridge retainer for holding a medicament cartridge. A dispense interface can be attached to an attachment of the device for facilitating fluidic communication from the device. Further, an interface sensor is configured to provide an output indicative of whether the dispense interface is attached to the attachment. The device also comprises a piston rod for driving a bung of the medicament cartridge, and a drive train for advancing the piston rod to the bung. A controller is configured to control the drive train to advance the piston rod towards the bung when the output of the interface sensor indicates that the dispense interface is not on the attachment. The controller is further configured to disable advancement of the piston rod when the output of the interface sensor indicates that the dispense interface is at least partially on the attachment.

Abstract translation: 示出了用于施用一种或多种药剂的药物递送装置。 该装置包括用于保持药剂盒的药剂盒保持器。 分配接口可以附接到设备的附件，以便于从设备的流体通信。 此外，接口传感器被配置为提供指示分配接口是否附接到附件的输出。 该装置还包括用于驱动药剂盒的塞子的活塞杆和用于将活塞杆推进到塞子的传动系。 当接口传感器的输出指示分配接口不在附件上时，控制器被配置为控制传动系将活塞杆推向塞子。 控制器还被配置为当接口传感器的输出指示分配接口至少部分地在附件上时，禁止活塞杆的前进。

公开(公告)号：WO2012025590A3

公开(公告)日：2012-11-15

申请号：PCT/EP2011064629

申请日：2011-08-25

Applicant: SANOFI AVENTIS DEUTSCHLAND ,  DAY SHANE ALISTAIR ,  YATES BARRY ,  AVERY RICHARD JAMES VINCENT

Inventor： DAY SHANE ALISTAIR ,  YATES BARRY ,  AVERY RICHARD JAMES VINCENT

IPC: A61M5/24 ,  G06F19/00

CPC classification number: A61M5/5086 ,  A61M2205/60 ,  G06F19/3462

Abstract: Disclosed herein are methods and systems for detecting information related to a drug reservoir (320, 1000, 1002, 1006, 1008). According to one example disclosed herein, a method includes a detector feature (100, 500, 600, 700, 904) determining an electrical property related to a coded material (120, 502, 606, 708, 900) for a drug reservoir (320, 1000, 1002, 1006, 1008), wherein the coded material (120, 502, 606, 708, 900) comprises at least one circuit (122, 400, 800, 802, 804a-e, 902, 906, 908). The at least one circuit (122, 400, 800, 802, 804a-e, 902, 906, 908) may be printed onto the drug reservoir (320, 1000, 1002, 1006, 1008). The method further includes determining information related to the drug reservoir (320, 1000, 1002, 1006, 1008) based at least on the determined electrical property.

Abstract translation: 本文公开了用于检测与药物储存器（320,1000,1002,1006,1008）有关的信息的方法和系统。 根据本文公开的一个示例，一种方法包括：确定与用于药物储存器（320）的编码材料（120,502,606,708,900）相关的电特性的检测器特征（100,500,600,700,904） ，其中编码材料（120,502,606,708,900）包括至少一个电路（122,400,800，802,804a-e，902,906,908）。 该至少一个电路（122,400,800,802,804a-e，902,906,908）可以被印刷到药物储存器（320,1000,1002,1006,1008）上。 该方法还包括至少基于所确定的电特性来确定与药物储存器（320,1000,1002,1006,1008）有关的信息。

公开(公告)号：WO2008090317A1

公开(公告)日：2008-07-31

申请号：PCT/GB2008/000195

申请日：2008-01-21

Applicant: CONSORT MEDICAL PLC ,  WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David,

Inventor： WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David,

IPC: F16K11/074

CPC classification number: F16K11/074 ,  B05B3/025 ,  B05B3/026 ,  B05B12/06 ,  B65D83/262 ,  B65D83/54

Abstract: A metering valve (1) for a pressurised dispensing container comprising a metering chamber (5); an inlet (9) to the metering chamber and a separate outlet (10) to the metering chamber; one or more sealing members (7, 8) for sealing the inlet (9) to the metering chamber (5) and the outlet (10) to the metering chamber (5). The one or more sealing members (7, 8) are static and the metering chamber (5) is rotatable between a first position, in which the inlet (9) to the metering chamber is open and the outlet (10) to the metering chamber is closed, and a second position, in which the inlet (9) to the metering chamber is closed and the outlet (10) to the metering chamber is open.

Abstract translation: 一种用于加压分配容器的计量阀（1），包括计量腔（5）; 到计量室的入口（9）和到计量室的单独出口（10）; 用于将入口（9）密封到计量室（5）和出口（10）到计量室（5）的一个或多个密封构件（7,8）。 一个或多个密封构件（7,8）是静态的，并且计量室（5）可在第一位置和第二位置之间旋转，第一位置与计量室的入口（9）打开，而出口（10） 关闭，并且第二位置，其中计量室的入口（9）关闭并且到计量室的出口（10）是打开的。

公开(公告)号：WO2003047659A1

公开(公告)日：2003-06-12

申请号：PCT/GB2002/005483

申请日：2002-12-05

Applicant: DCA DESIGN INTERNATIONAL LIMITED ,  LANGLEY, Christopher, Nigel ,  DAY, Shane, Alistair ,  GARDNER, Paul, William ,  MOLYNEUX, Brian, Charles

Inventor： LANGLEY, Christopher, Nigel ,  DAY, Shane, Alistair ,  GARDNER, Paul, William ,  MOLYNEUX, Brian, Charles

IPC: A61M5/145

CPC classification number: A61M5/14566 ,  A61M2205/50 ,  A61M2205/6027

Abstract: Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that different forms of medicament do not become confused and that the patient does not receive an incorrect medicament. In order to meet the appropriate standard, certain dimensional restrictions are placed upon the cartridge. A medicament cartridge (2, 2') that meets the requirements of this standard and permits more ready discrimination between medicament cartridges having different contents is provided. The medicament cartridge (2, 2') of the present invention is provided with an electrical element (12) having specified electrical properties located on an external face of a displaceable plunger (6, 6').

Abstract translation: 许多患有糖尿病的患者结合了缓慢和快速作用的胰岛素。 重要的是不同形式的药物不会变得混淆，并且患者不接受不正确的药物。 为了达到适当的标准，某些尺寸限制放置在墨盒上。 提供了满足本标准要求并且允许更容易区分具有不同内容的药剂盒之间的药剂盒（2,2'）。 本发明的药剂盒（2,2'）设置有具有位于可移动柱塞（6,6'）的外表面上的特定电气特性的电气元件（12）。

公开(公告)号：WO2012160159A1

公开(公告)日：2012-11-29

申请号：PCT/EP2012/059751

申请日：2012-05-24

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH ,  EGGERT, Ilona ,  LANGLEY, Christopher Nigel ,  DAY, Shane Alistair ,  JAMES, Aled Meredydd

Inventor： EGGERT, Ilona ,  LANGLEY, Christopher Nigel ,  DAY, Shane Alistair ,  JAMES, Aled Meredydd

IPC: A61M5/24 ,  A61M5/20 ,  A61M5/142 ,  A61M5/34

CPC classification number: A61M5/5086 ,  A61M5/20 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/31543 ,  A61M5/34 ,  A61M2005/14268 ,  A61M2205/14 ,  A61M2205/50 ,  A61M2205/6018 ,  F04C2270/041

Abstract: A medicament delivery device is presented for the administration of one or more drug agents, wherein the device comprises a retainer for holding a medicament cartridge. The retainer is moveable between an open and closed position. A position sensor for generating a position output is indicative of whether the retainer is in the open or closed position. Further, a cartridge sensor generates a cartridge output indicative of whether the retainer is holding a medicament cartridge. A controller controls a predetermined operation of the device in dependence on the output of the position sensor and on the output of the cartridge sensor.

Abstract translation: 呈现用于施用一种或多种药剂的药物输送装置，其中所述装置包括用于保持药剂盒的保持器。 保持器可在打开和关闭位置之间移动。 用于产生位置输出的位置传感器指示保持器是处于打开或关闭位置。 此外，盒式传感器产生指示保持器是否保持药剂盒的盒输出。 控制器根据位置传感器的输出和墨盒传感器的输出来控制设备的预定操作。

公开(公告)号：WO2011089205A3

公开(公告)日：2011-09-29

申请号：PCT/EP2011050797

申请日：2011-01-21

Applicant: SANOFI AVENTIS DEUTSCHLAND ,  DAY SHANE ALISTAIR ,  YATES BARRY ,  AVERY RICHARD JAMES VINCENT

Inventor： DAY SHANE ALISTAIR ,  YATES BARRY ,  AVERY RICHARD JAMES VINCENT

IPC: A61M5/24 ,  G06F19/00 ,  G06K7/10 ,  G06K7/14

CPC classification number: G06K7/10 ,  A61M5/00 ,  A61M5/1452 ,  A61M5/20 ,  A61M5/24 ,  A61M5/2425 ,  A61M5/31525 ,  A61M5/31546 ,  A61M5/31583 ,  A61M5/482 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M2005/2407 ,  A61M2005/2496 ,  A61M2005/3125 ,  A61M2205/12 ,  A61M2205/18 ,  A61M2205/27 ,  A61M2205/276 ,  A61M2205/43 ,  A61M2205/44 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2205/6009 ,  A61M2205/6063 ,  A61M2205/6081 ,  G06F19/3468 ,  G06K7/12 ,  G06K19/06037 ,  G16H20/17

Abstract: A method (900, 1000) and system (100, 700) for detecting information related to a drug reservoir (400, 800). The method (900, 1000) includes transmitting energy (103) at a coded material (120) disposed on a drug reservoir (400, 800), where the energy (103) has at least one predefined characteristic. The coded material (120) identifies information related to the drug reservoir (400, 800). The coded material (120) modifies the energy (103) and emits the modified energy (105) to a receiver (107, 707). The method (900, 1000) further includes receiving at the receiver (107, 707) the modified energy (105). The method (900, 1000) further includes determining information related to the drug reservoir (400, 800) based on the modified energy (105) as the drug reservoir (400, 800) is loaded into a drug delivery device (600, 1100).

Abstract translation: 一种用于检测与药物储存器（400,800）有关的信息的方法（900,1000）和系统（100,700）。 方法（900,1000）包括以设置在药物储存器（400,800）上的编码材料（120）传输能量（103），其中能量（103）具有至少一个预定特征。 编码材料（120）识别与药物储存器（400,800）有关的信息。 编码材料（120）修改能量（103）并将修改的能量（105）发射到接收器（107,707）。 方法（900,1000）还包括在接收器（107,707）处接收修改的能量（105）。 方法（900,1000）还包括当药物储存器（400,800）装载到药物输送装置（600,1100）中时，基于修改的能量（105）确定与药物储存器（400,800）有关的信息， 。

公开(公告)号：WO2011067187A1

公开(公告)日：2011-06-09

申请号：PCT/EP2010/068358

申请日：2010-11-29

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH ,  DAY, Shane Alistair ,  DE SAUSMAREZ LINTELL, Daniel Thomas ,  WIMPENNY, Steven ,  JONES, Christopher ,  O'HARE, Aidan Michael ,  YATES, Barry ,  VEASEY, Robert ,  SMITH, Christopher James ,  BOYD, Malcolm ,  LEAK, David Martin ,  KEATING, Carmen Patricia ,  SANDERS, David ,  MARSHALL, Elizabeth Anne

Inventor： DAY, Shane Alistair ,  DE SAUSMAREZ LINTELL, Daniel Thomas ,  WIMPENNY, Steven ,  JONES, Christopher ,  O'HARE, Aidan Michael ,  YATES, Barry ,  VEASEY, Robert ,  SMITH, Christopher James ,  BOYD, Malcolm ,  LEAK, David Martin ,  KEATING, Carmen Patricia ,  SANDERS, David ,  MARSHALL, Elizabeth Anne

IPC: A61M5/172 ,  A61M5/142 ,  A61M5/315 ,  A61M5/00

CPC classification number: A61M5/19 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/1723 ,  A61M5/20 ,  A61M5/24 ,  A61M5/31511 ,  A61M5/31525 ,  A61M5/31546 ,  A61M5/31583 ,  A61M5/3202 ,  A61M5/3294 ,  A61M5/3295 ,  A61M5/347 ,  A61M2005/2407 ,  A61M2005/2411 ,  A61M2005/2496 ,  A61M2005/3126 ,  A61M2005/31518 ,  A61M2005/31588 ,  A61M2205/14 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/6063 ,  A61M2205/6072 ,  A61M2205/8206

Abstract: A computerized electro-mechanical drug delivery device (10) configured to deliver at least one dose of two or more medicaments. The device comprises a control unit (300). An electro-mechanical drive unit (500, 600) is operably coupled to the control unit and a primary reservoir (90) for a first medicament and a secondary reservoir (100) for a fluid agent, e.g. a second medicament. An operator interface (60) is in communication with the control unit (300). A single dispense assembly (200) is configured for fluid communication with the primary (90) and the secondary (100) reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile (860), the control unit (300) is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament.

Abstract translation: 一种计算机化的机电药物递送装置（10），其被配置为递送至少一个剂量的两种或更多种药物。 该装置包括控制单元（300）。 机电驱动单元（500,600）可操作地联接到控制单元和用于第一药剂的主储存器（90）和用于流体剂的第二储存器（100） 第二种药物。 操作者接口（60）与控制单元（300）通信。 单个分配组件（200）被配置为与初级（90）和次级（100）储存器流体连通。 操作面板的激活设定来自主贮存器的第一剂量，并且基于第一剂量和治疗剂量分布（860），控制单元（300）被配置为确定流体试剂的剂量或范围。 或者，控制单元确定或计算第三药剂的剂量或范围。