公开(公告)号：WO2013049596A2

公开(公告)日：2013-04-04

申请号：PCT/US2012/057959

申请日：2012-09-28

Applicant: THE PENN STATE RESEARCH FOUNDATION ,  HEDGE, Narasimha ,  DEBROY, Chitrita ,  KAPUR, Vivek

Inventor： HEDGE, Narasimha ,  DEBROY, Chitrita ,  KAPUR, Vivek

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N33/56911 ,  G01N33/6878

Abstract: Methods for the detection, identification and quantification of gram negative bacteria and gram negative bacterial antigens are rapid, efficient and highly specific. Compositions for the detection and identification of highly variable serogroups are provided.

Abstract translation: 用于检测，鉴定和定量革兰氏阴性细菌和革兰氏阴性细菌抗原的方法是快速，有效和高度特异性的。 提供用于检测和鉴定高度可变血清群的组合物。

公开(公告)号：WO2012162681A2

公开(公告)日：2012-11-29

申请号：PCT/US2012/039747

申请日：2012-05-25

Applicant: E. I. DU PONT DE NEMOURS AND COMPANY ,  COBB, Michael W. ,  HARMER, Mark Andrew ,  KAPUR, Vivek ,  LIAUW, Ann Y ,  WILLIAMS, Sharlene Renee

Inventor： COBB, Michael W. ,  HARMER, Mark Andrew ,  KAPUR, Vivek ,  LIAUW, Ann Y ,  WILLIAMS, Sharlene Renee

IPC: C08J9/00

CPC classification number: C08J9/146 ,  B29C44/02 ,  B29C44/3415 ,  B29K2061/00 ,  B29K2105/046 ,  B29K2995/0015 ,  B29K2995/0016 ,  B29L2031/10 ,  B32B5/18 ,  C08J9/0061 ,  C08J9/14 ,  C08J9/141 ,  C08J2203/162 ,  C08J2361/06 ,  C08J2361/12 ,  C08J2497/00 ,  C08J2499/00 ,  E04C2/284 ,  Y10T428/249976

Abstract: Disclosed are foam compositions and processes to form mixed tannin-phenolic foams. The foams comprises a continuous polymeric phase defining a plurality of cells, wherein the continuous polymeric phase comprises a mixed-resin derived from a phenol, a tannin, and a first monomer, and wherein the plurality of cells comprises a plurality of open-cells and a plurality of closed-cells with an open-cell content measured according to ASTM D6226-5, of less than 50%. The foam composition also comprises a discontinuous phase disposed in at least a portion of the plurality of closed-cells, the discontinuous phase comprising one or more blowing agents.

Abstract translation: 公开了形成混合单宁 - 酚醛泡沫的泡沫组合物和方法。 泡沫包括限定多个细胞的连续聚合物相，其中连续聚合物相包含衍生自苯酚，单宁和第一单体的混合树脂，并且其中所述多个细胞包含多个开放细胞和 根据ASTM D6226-5测量的具有开孔含量的多个闭孔小于50％。 所述泡沫组合物还包括设置在所述多个闭孔的至少一部分中的不连续相，所述不连续相包含一种或多种发泡剂。

公开(公告)号：WO2004074310A8

公开(公告)日：2004-12-23

申请号：PCT/IB0306509

申请日：2003-03-06

Applicant: UNIV MINNESOTA ,  US AGRICULTURE ,  KAPUR VIVEK ,  BANNANTINE JOHN P ,  LI LING-LING ,  AMONSIN ALONGKORN ,  ZHANG QING

Inventor： KAPUR VIVEK ,  BANNANTINE JOHN P ,  LI LING-LING ,  AMONSIN ALONGKORN ,  ZHANG QING

IPC: A61K39/04 ,  C07H21/00 ,  C07K20060101 ,  C07K1/00 ,  C07K14/35 ,  C07K16/12 ,  C12N15/31 ,  C12Q1/68 ,  G01N20060101 ,  G01N33/569 ,  A61K49/00 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/00

CPC classification number: C12Q1/689 ,  C12Q2600/16

Abstract: The present invention provides nucleic acid molecules unique to M. paratuberculosis. The invention also provides the polypeptides encoded by the M. paratuberculosis- specific nucleic acid molecules of the invention, and antibodies having specific binding affinity for the polypeptides encoded by the paratuberculosis- specific nucleic acid molecules. The invention further provides for methods of detecting M. paratuberculosis in a sample using nucleic acid molecules, polypeptides, and antibodies of the invention. The invention additionally provides methods of preventing a M. paratuberculosis infection in an animal.

Abstract translation: 本发明提供了副结核分枝杆菌特有的核酸分子。 本发明还提供了由本发明的副结核分枝杆菌特异性核酸分子编码的多肽，以及对由副结核分支特异性核酸分子编码的多肽具有特异性结合亲和力的抗体。 本发明还提供了使用本发明的核酸分子，多肽和抗体检测样品中副结核分枝杆菌的方法。 本发明另外提供了防止动物中副结核分枝杆菌感染的方法。

公开(公告)号：WO2004018638A8

公开(公告)日：2004-10-28

申请号：PCT/US0326488

申请日：2003-08-21

Applicant: UNIV MINNESOTA ,  KAPUR VIVEK ,  GADGIL MUGDHA

Inventor： KAPUR VIVEK ,  GADGIL MUGDHA

IPC: C07K14/47 ,  C07K14/705 ,  C12N9/10 ,  C07H21/04 ,  C07K17/00 ,  C12N15/00 ,  C12Q1/48

CPC classification number: C07K14/705 ,  C07K14/47

Abstract: Applicants have discovered previously uncharacterized genes and proteins that are involved in iron transport and/or metabolism. Accordingly, the present invention provides proteins involved in iron transport and/or metabolism and polynucleotides encoding those proteins. The present invention also provides expression cassettes containing the polynucleotides. The present invention also provides cells containing the expression cassettes, polypeptides, and/or polynucleotides of the invention.

Abstract translation: 申请人已经发现了先前未表征的参与铁转运和/或代谢的基因和蛋白质。 因此，本发明提供了参与铁运输和/或代谢的蛋白质和编码这些蛋白质的多核苷酸。 本发明还提供含有多核苷酸的表达盒。 本发明还提供含有本发明的表达盒，多肽和/或多核苷酸的细胞。

公开(公告)号：WO2012162656A3

公开(公告)日：2014-08-28

申请号：PCT/US2012039687

申请日：2012-05-25

Applicant: DU PONT ,  COBB MICHAEL W ,  GALANTE VINCENT ,  HARMER MARK ANDREW ,  KAPUR VIVEK ,  WILLIAMS SHARLENE RENEE

Inventor： COBB MICHAEL W ,  GALANTE VINCENT ,  HARMER MARK ANDREW ,  KAPUR VIVEK ,  WILLIAMS SHARLENE RENEE

IPC: C08J9/12 ,  B32B5/18

CPC classification number: C08J9/12 ,  B32B5/022 ,  B32B5/024 ,  B32B5/18 ,  B32B7/12 ,  B32B13/045 ,  B32B15/046 ,  B32B15/18 ,  B32B15/20 ,  B32B21/047 ,  B32B27/065 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B29/007 ,  B32B2250/40 ,  B32B2255/26 ,  B32B2266/02 ,  B32B2266/0214 ,  B32B2266/0228 ,  B32B2266/0278 ,  B32B2266/06 ,  B32B2266/08 ,  B32B2266/104 ,  B32B2266/126 ,  B32B2307/304 ,  B32B2419/00 ,  C08G65/40 ,  C08J9/141 ,  C08J9/146 ,  C08J2205/052 ,  C08J2397/00 ,  C08J2399/00 ,  C08J2459/00 ,  Y10T428/249976

Abstract: Disclosed are foam compositions and processes to form closed-cell tannin-based foams. The process comprises forming an agglomerate-free solution comprising a tannin, a first monomer, a second monomer, and water, wherein the first monomer comprises formaldehyde, paraformaldehyde, furfural, glyoxal, acetaldehyde, 5-hydroxymethylfurfural, acroleim, levulinate esters, sugars, 2,5-furandicarboxylic acid, 2,5-furandicarboxylic aldehyde, urea, difurfural (DFF), or mixtures thereof, and the second monomer comprises furfuryl alcohol, glycerol, sorbitol, lignin, or mixtures thereof. The process also comprises mixing one or more blowing agents with the agglomerate-free solution to form a pre-foam mixture and mixing an acid catalyst with the pre-foam mixture to form a foam composition. The process comprises adding a surfactant to at least one of the agglomerate-free solution, pre-foam mixture, or the foam composition. The process further comprises processing the foam composition to form a tannin-based foam.

Abstract translation: 公开了形成闭孔单宁单体泡沫的泡沫组合物和方法。 该方法包括形成包含单宁，第一单体，第二单体和水的无聚集体溶液，其中第一单体包含甲醛，多聚甲醛，糠醛，乙二醛，乙醛，5-羟甲基糠醛，丙烯酰胺，乙酰丙酸酯，糖， 2,5-呋喃二羧酸，2,5-呋喃二羧醛，脲，二氟乙酸（DFF）或其混合物，第二单体包括糠醇，甘油，山梨糖醇，木质素或其混合物。 该方法还包括将一种或多种发泡剂与无附聚物溶液混合以形成预泡沫混合物并将酸催化剂与预泡沫混合物混合以形成泡沫组合物。 该方法包括向至少一种无附聚物溶液，预泡沫混合物或泡沫组合物中加入表面活性剂。 该方法还包括加工泡沫组合物以形成单宁类泡沫。

公开(公告)号：WO2012162645A3

公开(公告)日：2013-03-28

申请号：PCT/US2012039668

申请日：2012-05-25

Applicant: DU PONT ,  HARMER MARK ANDREW ,  KAPUR VIVEK ,  WILLIAMS SHARLENE RENEE

Inventor： HARMER MARK ANDREW ,  KAPUR VIVEK ,  WILLIAMS SHARLENE RENEE

IPC: C08J9/12 ,  B32B5/18

CPC classification number: C08J9/12 ,  B32B5/022 ,  B32B5/024 ,  B32B5/18 ,  B32B7/12 ,  B32B13/045 ,  B32B15/046 ,  B32B15/18 ,  B32B15/20 ,  B32B21/047 ,  B32B27/065 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B29/007 ,  B32B2250/40 ,  B32B2255/26 ,  B32B2266/02 ,  B32B2266/0214 ,  B32B2266/0228 ,  B32B2266/0278 ,  B32B2266/06 ,  B32B2266/08 ,  B32B2266/104 ,  B32B2266/126 ,  B32B2307/304 ,  B32B2419/00 ,  C08G65/40 ,  C08J9/141 ,  C08J9/146 ,  C08J2205/052 ,  C08J2397/00 ,  C08J2399/00 ,  C08J2459/00 ,  Y10T428/249976

Abstract: Disclosed are foam compositions and processes to form closed-cell tannin-based foams. The process comprises forming an agglomerate-free solution comprising a tannin, a monomer, and water, wherein the monomer comprises furfural, glyoxal, acetaldehyde, 5-hydroxymethylfurfural, acrolein, levulinate esters, sugars, 2,5-furandicarboxylic acid, 2,5-furandicarboxylic aldehyde, urea, difurfural (DFF), furfuryl alcohol, glycerol, sorbitol, lignin, or mixtures thereof. The process also comprises mixing one or more blowing agents with the agglomerate-free solution to form a pre-foam mixture and mixing an acid catalyst with the pre-foam mixture to form a foam composition. The process comprises adding a surfactant to at least one of the agglomerate-free solution, pre-foam mixture, or the foam composition. The process further comprises processing the foam composition to form a tannin-based foam.

Abstract translation: 公开了形成闭孔单宁单体泡沫的泡沫组合物和方法。 该方法包括形成包含鞣酸，单体和水的无聚集体溶液，其中单体包含糠醛，乙二醛，乙醛，5-羟甲基糠醛，丙烯醛，乙酰丙酸酯，糖，2,5-呋喃二羧酸，2,5 （DFF），糠醇，甘油，山梨糖醇，木质素或其混合物。 该方法还包括将一种或多种发泡剂与无附聚物溶液混合以形成预泡沫混合物并将酸催化剂与预泡沫混合物混合以形成泡沫组合物。 该方法包括向至少一种无附聚物溶液，预泡沫混合物或泡沫组合物中加入表面活性剂。 该方法还包括加工泡沫组合物以形成单宁类泡沫。

公开(公告)号：WO2012162678A2

公开(公告)日：2012-11-29

申请号：PCT/US2012/039741

申请日：2012-05-25

Applicant: E. I. DU PONT DE NEMOURS AND COMPANY ,  COBB, Michael W. ,  HARMER, Mark Andrew ,  KAPUR, Vivek ,  LIAUW, Ann Y ,  WILLIAMS, Sharlene Renee

Inventor： COBB, Michael W. ,  HARMER, Mark Andrew ,  KAPUR, Vivek ,  LIAUW, Ann Y ,  WILLIAMS, Sharlene Renee

IPC: C08J9/14

CPC classification number: C08L61/06 ,  B32B5/18 ,  B32B2250/03 ,  B32B2250/40 ,  B32B2266/0285 ,  B32B2266/06 ,  B32B2266/08 ,  B32B2305/022 ,  B32B2307/304 ,  B32B2307/3065 ,  B32B2307/72 ,  C08J9/146 ,  C08J2203/162 ,  C08J2205/052 ,  C08J2361/06 ,  Y10T428/249976

Abstract: Disclosed are foam compositions and processes to form closed-cell phenolic foams. The foams comprises a continuous polymeric phase defining a plurality of cells, wherein the continuous polymeric phase comprises a phenol-formaldehyde resole derived from a phenol and formaldehyde, and wherein the plurality of cells comprises a plurality of open-cells and a plurality of closed-cells with an open-cell content measured according to ASTM D6226-5, of less than 50%. The foam composition also comprises a discontinuous phase disposed in at least a portion of the plurality of closed-cells, the discontinuous phase comprising 1,1,1,4,4,4-hexafluoro-2-butene

Abstract translation: 公开了形成闭孔酚醛泡沫的泡沫组合物和方法。 所述泡沫包括限定多个细胞的连续聚合物相，其中所述连续聚合物相包含衍生自苯酚和甲醛的苯酚 - 甲醛甲阶酚醛树脂，并且其中所述多个细胞包含多个开放细胞和多个闭合细胞， 具有根据ASTM D6226-5测量的开孔含量小于50％的细胞。 所述泡沫组合物还包括设置在所述多个闭孔中的至少一部分中的不连续相，所述不连续相包含1,1,1,4,4,4-六氟-2-丁烯

公开(公告)号：WO2006078280A2

公开(公告)日：2006-07-27

申请号：PCT/US2005/014682

申请日：2005-04-29

Applicant: E.I. DUPONT DE NEMOURS AND COMPANY ,  TRENTACOSTA, Joseph, D. ,  KAPUR, Vivek

Inventor： TRENTACOSTA, Joseph, D. ,  KAPUR, Vivek

IPC: A41D31/00 ,  B01D69/02 ,  B01D69/12 ,  B32B5/00 ,  B32B5/02

CPC classification number: B01D69/12 ,  A41D27/28 ,  A41D31/0016 ,  A41D2400/22 ,  A62B17/006 ,  B01D39/1692 ,  B01D69/02 ,  B01D2239/0241 ,  B01D2239/0407 ,  B01D2239/0414 ,  B01D2239/0442 ,  B01D2239/0471 ,  B01D2325/08 ,  B01D2325/26 ,  B01D2325/48 ,  B01J20/28033 ,  B32B3/266 ,  B32B5/26 ,  B32B2250/02 ,  B32B2250/20 ,  B32B2255/02 ,  B32B2255/205 ,  B32B2255/26 ,  B32B2255/28 ,  B32B2437/00 ,  B32B2571/02 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0025 ,  F16K99/0051 ,  F16K2099/008 ,  G05D21/02 ,  G05D22/02 ,  G05D23/19 ,  G05D23/192 ,  Y10S251/904 ,  Y10T428/24322 ,  Y10T428/24331 ,  Y10T428/24339 ,  Y10T436/163333

Abstract: The present invention relates to a porous adaptive membrane structure that has movable membranes. The structure can be made to change its gas, liquid or particulate permeability in response to surrounding environmental conditions. The application of this invention is includes protective apparel that is comfortable to wear wherein the level of protection provided is based on conditions in the environment. Hence, the protective apparel is highly breathable and comfortable in a non-hazardous environment but impermeable or only semipermeable in a hazardous environment.

Abstract translation: 本发明涉及一种具有可移动膜的多孔适应膜结构。 可以根据周围环境条件改变其气体，液体或微粒的渗透性。 本发明的应用包括穿着舒适的防护服，其中所提供的防护等级是基于环境条件。 因此，防护服在非危险环境中具有高透气性和舒适性，但在危险环境中不透水或仅渗透半透明。

公开(公告)号：WO2004074310A3

公开(公告)日：2006-02-23

申请号：PCT/IB0306509

申请日：2003-03-06

Applicant: UNIV MINNESOTA ,  US AGRICULTURE ,  KAPUR VIVEK ,  BANNATINE JOHN P ,  LI LING-LING ,  AMONSIN ALONGKORN ,  ZHANG QING

Inventor： KAPUR VIVEK ,  BANNATINE JOHN P ,  LI LING-LING ,  AMONSIN ALONGKORN ,  ZHANG QING

IPC: A61K39/04 ,  C07H21/00 ,  C07K20060101 ,  C07K1/00 ,  C07K14/35 ,  C07K16/12 ,  C12N15/31 ,  C12Q1/68 ,  G01N20060101 ,  G01N33/569 ,  A61K49/00 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/00

CPC classification number: C12Q1/689 ,  C12Q2600/16

Abstract: The present invention provides nucleic acid molecules unique to M. paratuberculosis. The invention also provides the polypeptides encoded by the M. paratuberculosis- specific nucleic acid molecules of the invention, and antibodies having specific binding affinity for the polypeptides encoded by the paratuberculosis- specific nucleic acid molecules. The invention further provides for methods of detecting M. paratuberculosis in a sample using nucleic acid molecules, polypeptides, and antibodies of the invention. The invention additionally provides methods of preventing a M. paratuberculosis infection in an animal.

公开(公告)号：WO9608569A3

公开(公告)日：1996-07-18

申请号：PCT/US9511723

申请日：1995-09-13

Applicant: BAYLOR COLLEGE MEDICINE ,  MUSSER JAMES A ,  KAPUR VIVEK

Inventor： MUSSER JAMES A ,  KAPUR VIVEK

IPC: C12N15/09 ,  A61K39/00 ,  A61K39/09 ,  A61P7/00 ,  A61P11/04 ,  A61P13/12 ,  A61P17/00 ,  A61P29/00 ,  A61P31/04 ,  C07K7/06 ,  C07K7/08 ,  C07K14/315 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/52 ,  C12N15/02 ,  C12N15/57 ,  C12P21/08 ,  C12Q1/14 ,  C12Q1/37 ,  C12Q1/68 ,  C12R1/46 ,  G01N33/53 ,  G01N33/566 ,  G01N33/569 ,  G01N33/573 ,  G01N33/577 ,  C07K16/40 ,  C12N5/02

CPC classification number: G01N33/56944 ,  C12N9/52

Abstract: Methods and compositions are provided for identifying a group A Streptococcus in any of a variety of physiological samples, such as blood, saliva, throat swabs, cerebrospinal fluid, brocheolar lavage material, and biopsy material. The compositions used include an extracellular cysteine protease or a fragment thereof, obtainable from S. pyogenes and containing at least one conserved epitope, or nucleic acid encoding the cysteine protease or fragment thereof. The compositions also find use in eliciting a protective immune response against a group A Streptococcus infection.