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1.发明申请
公开(公告)号：WO2009098229A3
公开(公告)日：2010-05-27
申请号：PCT/EP2009051268
申请日：2009-02-04
Applicant: DANISCO US INC GENENCOR DIV , DANISCO , KRAGH KARSTEN MATTHIAS , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER WILLEM , WEYLER WALTER , PEREIRA LUIS GUSTAVO CASCAO , KELLIS JAMES T
Inventor： KRAGH KARSTEN MATTHIAS , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER WILLEM , WEYLER WALTER , PEREIRA LUIS GUSTAVO CASCAO , KELLIS JAMES T
CPC classification number: C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
Abstract: The present invention relates to the use of a parent AmyTS-23 alpha-amylase as well as variants, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase in the production of food products, such as the use in a baking composition.
Abstract translation: 本发明涉及母体AmyTS-23α-淀粉酶以及变体，其中变体具有α-淀粉酶活性并在食品生产中相对于母体α-淀粉酶具有改变的性质，例如使用 在烘焙组合物中。
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公开(公告)号：WO2012001139A9
公开(公告)日：2012-02-23
申请号：PCT/EP2011061082
申请日：2011-06-30
Applicant: DANISCO , DANISCO US INC , DEGN PETER EDVARD , BOTT RICHARD R , VROEMEN CASPER WILLEM , SCHEFFERS MARTIJN SILVAN , AEHLE WOLFGANG , PETERSEN ELIN
Inventor： DEGN PETER EDVARD , BOTT RICHARD R , VROEMEN CASPER WILLEM , SCHEFFERS MARTIJN SILVAN , AEHLE WOLFGANG , PETERSEN ELIN
CPC classification number: C12N9/2408 , A23L29/35 , C12C5/004 , C12C7/04 , C12N9/2428 , C12P19/02 , C12P19/20 , C12Y302/01003 , C13K1/06 , Y02P20/52
Abstract: The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
Abstract translation: 本发明涉及母体葡糖淀粉酶的组合变体，其在淀粉水解期间具有降低缩合产物合成的性质。 因此，母体葡糖淀粉酶的变体是适合的，例如用于酿造和葡萄糖浆生产中。 还公开了编码在宿主细胞中产生葡糖淀粉酶变体的变体和方法的DNA构建体。
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公开(公告)号：WO2009100102A2
公开(公告)日：2009-08-13
申请号：PCT/US2009/033027
申请日：2009-02-04
Applicant: DANISCO US INC., GENENCOR DIVISION , CASCAO-PEREIRA, Luis , CHANG, Claudine , CHOY, Clement , ESTABROOK, Melodie , JONES, Brian, E. , KELLIS, James, T., Jr. , KOLKMAN, Marc , LEEFLANG, Chris , VROEMEN, Casper , WEYLER, Walter
Inventor： CASCAO-PEREIRA, Luis , CHANG, Claudine , CHOY, Clement , ESTABROOK, Melodie , JONES, Brian, E. , KELLIS, James, T., Jr. , KOLKMAN, Marc , LEEFLANG, Chris , VROEMEN, Casper , WEYLER, Walter
IPC: C07K14/435
CPC classification number: C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
Abstract translation: 描述了具有α-淀粉酶活性并且相对于母体α-淀粉酶具有改变的性质的亲本α-淀粉酶的变体（突变体）及其使用方法。
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公开(公告)号：WO2009048488A1
公开(公告)日：2009-04-16
申请号：PCT/US2008/004574
申请日：2008-04-08
Applicant: DANISCO US, INC., GENENCOR DIVISION , AEHLE, Wolfgang , BOTT, Richard, R. , NIKOLAEV, Igor , SCHEFFERS, Martijn , VAN SOLINGEN, Piet , VROEMEN, Casper
Inventor： AEHLE, Wolfgang , BOTT, Richard, R. , NIKOLAEV, Igor , SCHEFFERS, Martijn , VAN SOLINGEN, Piet , VROEMEN, Casper
CPC classification number: C12N9/2428 , Y02E50/17
Abstract: The present invention relates to variant glucoamylases wherein the variant has altered properties (e.g., improved thermostability and/or specific activity) compared to a corresponding parent glucoamylase. The present invention also relates to enzyme compositions comprising a variant glucoamylase (e.g., starch hydrolyzing compositions); DNA constructs comprising polynucleotides encoding the variants and methods of producing the variant glucoamylases in host cells
Abstract translation: 本发明涉及变体葡糖淀粉酶，其中与相应的母体葡糖淀粉酶相比，变体具有改变的性质（例如改善的热稳定性和/或比活性）。 本发明还涉及包含变体葡糖淀粉酶（例如淀粉水解组合物）的酶组合物; 包含编码变体的多核苷酸的DNA构建体和在宿主细胞中产生变体葡糖淀粉酶的方法
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公开(公告)号：WO2008024372A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/018523
申请日：2007-08-21
Applicant: DANISCO US, INC., GENENCOR DIVISION , ENGLAND, George , KOLKMAN, Marc , MILLER, Brian S. , VROEMEN, Casper
Inventor： ENGLAND, George , KOLKMAN, Marc , MILLER, Brian S. , VROEMEN, Casper
CPC classification number: C12Y302/01041 , C12N9/2457
Abstract: The invention relates to novel variants of the enzymatic peptide pullulanase, the gene sequences encoding said novel peptides, expression vectors comprising those gene sequences as well as organisms expressing the novel pullulanase variants. The novel pullulanase variants of the present invention were made empirically by the use of codon-optimization procedures, selective truncation of “wild-type” molecules and through the replacement of selected amino acid residues. Furthermore, the invention relates to the use of these novel pullulanase peptides in the textile, fermentation, food and other industries.
Abstract translation: 本发明涉及酶促支链淀粉酶的新变体，编码所述新肽的基因序列，包含那些基因序列的表达载体以及表达新型支链淀粉酶变体的生物。 通过使用密码子优化程序，选择性截短“野生型”分子和通过置换所选择的氨基酸残基，凭经验提供本发明的新型支链淀粉酶变体。 此外，本发明涉及这些新型支链淀粉酶肽在纺织，发酵，食品和其它工业中的用途。
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Patent Agency Ranking6.发明申请VARIANTS OF BACILLUS sp. TS-23 ALPHA-AMYLASE WITH ALTERED PROPERTIES 审中-公开BACILLUS sp。 具有改性特性的TS-23 ALPHA-AMYLASE
公开(公告)号：WO2009061380A8
公开(公告)日：2017-03-23
申请号：PCT/US2008012412
申请日：2008-11-03
Applicant: DANISCO US INC , SHAW ANDREW , RAMER SANDRA , POWER SCOTT D , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN E , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER , WEYLER WALTER , KRAGH KARSTEN M , GOYAL MANSI , GRAYCAR THOMAS , HUANG VICTORIA
Inventor： SHAW ANDREW , RAMER SANDRA , POWER SCOTT D , CHANG CLAUDINE , ESTABROOK MELODIE , JONES BRIAN E , CHOY CLEMENT , KOLKMAN MARC , LEEFLANG CHRIS , VROEMEN CASPER , WEYLER WALTER , KRAGH KARSTEN M , GOYAL MANSI , GRAYCAR THOMAS , HUANG VICTORIA
CPC classification number: C11D3/386 , C11D3/38681 , C12N9/2417
Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing / cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.
Abstract translation: 芽孢杆菌的变种 TS-23菌株α-淀粉酶表现出改善的酶性能，包括增加其稳定性，降低钙依赖性，提高洗涤/清洁性能和烘烤能力。 包含这些变体的组合物可用于淀粉加工，淀粉液化，粉化，淀粉糖化，清洗，洗衣，纺织品退浆，烘烤和生物膜除去的方法。
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7.发明申请COMPOSITIONS AND USES FOR AN ALPHA-AMYLASE POLYPEPTIDE OF BACILLUS SPECIES 195 审中-公开贝类物种的ALPHA-AMYLASE多肽的组合物和用途195
公开(公告)号：WO2008088493A3
公开(公告)日：2009-01-22
申请号：PCT/US2007024959
申请日：2007-12-06
Applicant: DANISCO US INC GENENCOR DIV , AMIN NEELAM S , ESTABROOK MELODIE , JONES BRIAN E , KOLKMAN MARC , MITCHINSON COLIN , VROEMEN CASPER , WEYLER WALTER
Inventor： AMIN NEELAM S , ESTABROOK MELODIE , JONES BRIAN E , KOLKMAN MARC , MITCHINSON COLIN , VROEMEN CASPER , WEYLER WALTER
CPC classification number: C12N9/2417
Abstract: Disclosed herein are compositions comprising an alpha-amylase enzyme obtained from Bacillus sp. no. 195, and methods of using the enzyme to clean surfaces and textiles. Also disclosed are variants of the enzyme with different signal sequences.
Abstract translation: 本文公开了包含从芽孢杆菌属（Bacillus sp。）获得的α-淀粉酶的组合物。 没有。 195，以及使用酶清洁表面和纺织品的方法。 还公开了具有不同信号序列的酶的变体。
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8.发明申请ENHANCED AMYLASE PRODUCTION BY N-TERMINAL ADDITION TO MATURE AMYLASE PROTEIN 审中-公开通过N末端添加成熟的淀粉酶蛋白增强了淀粉酶的生产
公开(公告)号：WO2008118377A3
公开(公告)日：2008-10-02
申请号：PCT/US2008/003778
申请日：2008-03-20
Applicant: DANISCO US, INC., GENENCOR DIVISION , ENGLAND, George , KOLKMAN, Marc , VROEMEN, Casper
Inventor： ENGLAND, George , KOLKMAN, Marc , VROEMEN, Casper
IPC: C12N15/52
Abstract: A method of making a Bacillus alpha-amylase variant that increases alpha-amylase production and the alpha-amylases produced thereby. The recombinant alpha-amylases can be placed in compositions and used for purposes of laundry detergents, cleaning and dishwashing detergents, fabric desizing, starch liquefaction, cereal liquefaction, starch saccharification, biofilm removal, and starch hydrolysis in cane sugar processing.
Abstract translation: 制备增加α-淀粉酶产生的芽孢杆菌属α-淀粉酶变体和由此产生的α-淀粉酶的方法。 可以将重组α-淀粉酶置于组合物中，并用于蔗糖加工中的洗衣洗涤剂，清洁和洗碟洗涤剂，织物退浆，淀粉液化，谷物液化，淀粉糖化，生物膜去除和淀粉水解。
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9.发明申请ENHANCED AMYLASE PRODUCTION BY N-TERMINAL ADDITION TO MATURE AMYLASE PROTEIN 审中-公开通过N-末端添加对成熟的AMYLASE蛋白的增强的AMYLASE生产
公开(公告)号：WO2008118377A2
公开(公告)日：2008-10-02
申请号：PCT/US2008003778
申请日：2008-03-20
Applicant: DANISCO US INC GENENCOR DIV , ENGLAND GEORGE , KOLKMAN MARC , VROEMEN CASPER
Inventor： ENGLAND GEORGE , KOLKMAN MARC , VROEMEN CASPER
IPC: D06L4/40
CPC classification number: C11D3/386 , C12N9/2417
Abstract: A method of making a Bacillus alpha-amylase variant that increases alpha-amylase production and the alpha-amylases produced thereby. The recombinant alpha-amylases can be placed in compositions and used for purposes of laundry detergents, cleaning and dishwashing detergents, fabric desizing, starch liquefaction, cereal liquefaction, starch saccharification, biofilm removal, and starch hydrolysis in cane sugar processing.
Abstract translation: 制备增加α-淀粉酶产生的芽孢杆菌α-淀粉酶变体和由此产生的α-淀粉酶的方法。 重组α-淀粉酶可以放置在组合物中，并用于蔗糖加工中洗衣洗涤剂，清洁和餐具洗涤剂，织物退浆，淀粉液化，谷物液化，淀粉糖化，生物膜去除和淀粉水解的目的。
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10.发明申请ALKALIPHILIC BACILLUS SPECIES A-AMYLASE VARIANTS, COMPOSITIONS COMPRISING A-AMYLASE VARIANTS, AND METHODS OF USE 审中-公开碱性玻璃菌属A-AMYLASE变种，包含α-氨基酸变体的组合物及其使用方法
公开(公告)号：WO2008112459A2
公开(公告)日：2008-09-18
申请号：PCT/US2008055780
申请日：2008-03-04
Applicant: DANISCO US INC GENENCOR DIV , CHANG CLAUDINE , DE NOBEL HANS , JONES BRIAN E , NAAB COREY , KOLKMAN MARC , VROEMEN CASPER , WEYLER WALTER
Inventor： CHANG CLAUDINE , DE NOBEL HANS , JONES BRIAN E , NAAB COREY , KOLKMAN MARC , VROEMEN CASPER , WEYLER WALTER
CPC classification number: C11D3/38609 , C11D3/38618 , C12N9/2417 , C12P19/14 , C12Y302/01001 , D06M16/003
Abstract: Disclosed are variants of the a-amylase derived from Bacillus sp. no. 707, compositions comprising said variants, compositions comprising the variants, and methods of using the variants. The methods of use include methods of cleaning surfaces, laundering textiles, desizing, hydrolyzing biofilms off various substrates, and treating starch (e.g., liquefaction and saccharification).
Abstract translation: 公开了衍生自芽孢杆菌属的α-淀粉酶的变体。 没有。 707，包含所述变体的组合物，包含变体的组合物和使用变体的方法。 使用的方法包括清洗表面，洗涤织物，脱浆，从各种底物上水解生物膜和处理淀粉（例如液化和糖化）的方法。
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