公开(公告)号：WO2012177624A3

公开(公告)日：2013-04-25

申请号：PCT/US2012043124

申请日：2012-06-19

Applicant: UNIV JOHNS HOPKINS ,  ZENG JING ,  DRAKE CHARLES GEORGE ,  PARDOLL DREW M ,  LIM MICHAEL

Inventor： ZENG JING ,  DRAKE CHARLES GEORGE ,  PARDOLL DREW M ,  LIM MICHAEL

IPC: A61K39/395 ,  A61K51/10 ,  A61P35/00

CPC classification number: A61N5/1001 ,  A61K39/39558 ,  A61K41/00 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2300/00 ,  A61N5/1042 ,  C07K16/24 ,  C07K16/2818 ,  C07K16/2878

Abstract: An approach combining immune-based therapies with focused radiation, including stereotactic radiation, to treat cancers is disclosed. The use of focused radiation primes the immune system in a similar manner to vaccines to augment immune-based therapies and can counteract the suppressive effects of a tumor. The combination of focused radiation and immune-based therapies, including administration of at least one immunotherapeutic agent, improves survival compared to each therapy alone and can, in some cases, lead to a durable cure. Accordingly, focused radiation can be an adjuvant for immune-based therapies for treating cancers.

Abstract translation: 公开了一种将基于免疫的疗法与聚焦辐射（包括立体定向辐射）结合治疗癌症的方法。 使用聚焦辐射以与疫苗相似的方式对免疫系统进行补充，以增强基于免疫的疗法，并可抵消肿瘤的抑制作用。 聚焦辐射和基于免疫的疗法的组合，包括施用至少一种免疫治疗剂，与单独的每种治疗相比，改善了存活，并且在一些情况下可以导致持久的治愈。 因此，聚焦辐射可以是用于治疗癌症的基于免疫的疗法的佐剂。

公开(公告)号：WO2007112311A2

公开(公告)日：2007-10-04

申请号：PCT/US2007064798

申请日：2007-03-23

Applicant: SBC KNOWLEDGE VENTURES LP ,  KATIBEH MO ,  FLORES JUAN G ,  MICHETICH ROBERT ,  JIANG BAOFENG ,  LIM MICHAEL

Inventor： KATIBEH MO ,  FLORES JUAN G ,  MICHETICH ROBERT ,  JIANG BAOFENG ,  LIM MICHAEL

IPC: H04L5/16

CPC classification number: H04L12/2856 ,  H04L1/24 ,  H04L41/0253 ,  H04L41/06 ,  H04L41/5009 ,  H04L41/5035 ,  H04L41/507 ,  H04L41/5074 ,  H04M3/306 ,  H04W4/18 ,  H04W8/26 ,  H04W24/00

Abstract: A method and system for managing performance data of communication lines, such as digital subscriber lines, is disclosed. The method includes receiving from a remote used device an identifier for a particular communication line at a web server; initiating a real-time performance analysis of the line at a network end of the line; receiving real-time performance data and converting the real-time performance data to analyze data; receiving field performance data from the user device; and converting at least one of the field performance data and the real-time performance data from a web-based format to a mainframe format; and sending the converted data to a mainframe for storage corresponding to a file associated with the identifier.

Abstract translation: 公开了一种用于管理诸如数字用户线路的通信线路的性能数据的方法和系统。 该方法包括从远程使用的设备接收web服务器上的特定通信线路的标识符; 在线路的网络端启动线路的实时性能分析; 接收实时性能数据并将实时性能数据转换为分析数据; 从用户设备接收现场演奏数据; 以及将所述现场演奏数据和所述实时演奏数据中的至少一个从基于网络的格式转换为主机格式; 并将转换的数据发送到与该标识符相关联的文件相对应的主机。

公开(公告)号：WO2006096794A8

公开(公告)日：2007-06-28

申请号：PCT/US2006008335

申请日：2006-03-07

Applicant: LUMINUS DEVICES INC ,  ERCHAK ALEXEI A ,  LIM MICHAEL ,  KARLICEK ROBERT F JR ,  BROWN MICHAEL GREGORY ,  VENEZIA JO A

Inventor： ERCHAK ALEXEI A ,  LIM MICHAEL ,  KARLICEK ROBERT F JR ,  BROWN MICHAEL GREGORY ,  VENEZIA JO A

IPC: G02F1/13357

CPC classification number: G02B6/0073 ,  G02B6/0018 ,  G02B6/4298 ,  G02F1/133615 ,  H01L2224/48091 ,  H01L2224/49113 ,  H01L2224/73265 ,  H04N9/315 ,  H04N9/3152 ,  H01L2924/00014

Abstract: A system including a panel (2212), a light emitting device (2202), and an optical component (2208) disposed in an optical path (2206, 2210) from the light emitting device (2202) to the edge (2211) of the panel (2212). The optical component (2208) includes an aperture, wherein a ratio of the area of the surface of the light emitting device (2202) to the area of the aperture is from about 0.5 to about 1.1.

Abstract translation: 一种系统，包括设置在从发光装置（2202）到光源（2202）的边缘（2211）的光路（2206,2210）中的面板（2212），发光装置（2202）和光学部件（2208） 面板（2212）。 光学元件（2208）包括孔径，其中发光器件（2202）的表面的面积与孔径的面积之比为约0.5至约1.1。

公开(公告)号：WO2006078522A3

公开(公告)日：2006-10-19

申请号：PCT/US2006000977

申请日：2006-01-12

Applicant: LUMINUS DEVICES INC ,  ERCHAK ALEXEI A ,  PANNACIONE PAUL ,  KARLICEK ROBERT F JR ,  LIM MICHAEL ,  LIDORIKIS ELEFTERIOS ,  VENEZIA JO A ,  HOEPFNER CHRISTIAN

Inventor： ERCHAK ALEXEI A ,  PANNACIONE PAUL ,  KARLICEK ROBERT F JR ,  LIM MICHAEL ,  LIDORIKIS ELEFTERIOS ,  VENEZIA JO A ,  HOEPFNER CHRISTIAN

IPC: H01L27/15 ,  H01L33/56 ,  H01L33/62

CPC classification number: H01L25/0753 ,  H01L33/56 ,  H01L33/62 ,  H01L2224/48091 ,  H01L2224/73265 ,  H01L2924/01012 ,  H01L2924/01046 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/12041 ,  H01L2924/12044 ,  H01L2924/00014 ,  H01L2924/00

Abstract: Light-emitting devices, and related components, processes, systems and methods are disclosed.

公开(公告)号：WO2006096767A1

公开(公告)日：2006-09-14

申请号：PCT/US2006/008225

申请日：2006-03-08

Applicant: LUMINUS DEVICES, INC. ,  ERCHAK, Alexei, A. ,  LIM, Michael ,  LIDORIKIS, Elefterios ,  VENEZIA, Jo, A. ,  KARLICEK, JR., Robert, F. ,  NEMCHUK, Nikolay, L.

Inventor： ERCHAK, Alexei, A. ,  LIM, Michael ,  LIDORIKIS, Elefterios ,  VENEZIA, Jo, A. ,  KARLICEK, JR., Robert, F. ,  NEMCHUK, Nikolay, L.

IPC: H01L33/00

CPC classification number: H01L33/22 ,  H01L33/20 ,  H01L33/24 ,  H01L2924/12041 ,  H01L2933/0083

Abstract: Light-emitting devices (e.g., LEDs) and methods associated with such devices are provided. The devices may include a first pattern and a second pattern which are formed at one or more interfaces of the device (e.g., the emission surface). The patterns may be positioned such that light generated by the device passes through the interfaces of the patterns when being emitted. The patterns can be defined by a series of features (e.g., vias, posts) having certain characteristics (e.g., feature size, depth, periodicity, nearest neighbor distance, etc.) which may be controlled to influence properties of the light emitted from the device, including improving extraction and/or collimation of the emitted light.

Abstract translation: 提供了与这种装置相关联的发光装置（例如，LED）和方法。 器件可以包括在器件的一个或多个界面（例如，发射表面）处形成的第一图案和第二图案。 可以将图案定位成使得由设备产生的光在发射时通过图案的界面。 这些图案可以由具有特定特征（例如，特征尺寸，深度，周期性，最近相邻距离等）的一系列特征（例如，通孔，柱）来定义，这些特征可被控制以影响从 装置，包括提高发射光的提取和/或准直。

公开(公告)号：WO2006096671A2

公开(公告)日：2006-09-14

申请号：PCT/US2006/007996

申请日：2006-03-07

Applicant: LUMINUS DEVICES, INC. ,  ERCHAK, Alexei, A. ,  LIM, Michael ,  KARLICEK, Robert, F., Jr. ,  BROWN, Michael, Gregory ,  VENEZIA, Jo, A.

Inventor： ERCHAK, Alexei, A. ,  LIM, Michael ,  KARLICEK, Robert, F., Jr. ,  BROWN, Michael, Gregory ,  VENEZIA, Jo, A.

IPC: H01L31/12

CPC classification number: G02B6/0073 ,  G02B6/0018 ,  G02B6/4298 ,  G02F1/133615 ,  H01L2224/48091 ,  H01L2224/49113 ,  H01L2224/73265 ,  H04N9/315 ,  H04N9/3152 ,  H01L2924/00014

Abstract: Light-emitting devices, and related components, processes, systems and methods are disclosed.

Abstract translation:

披露了发光器件及相关部件，工艺，系统和方法。

公开(公告)号：WO2006078522A2

公开(公告)日：2006-07-27

申请号：PCT/US2006/000977

申请日：2006-01-12

Applicant: LUMINUS DEVICES, INC. ,  ERCHAK, Alexei, A. ,  PANNACIONE, Paul ,  KARLICEK, Robert, F., Jr. ,  LIM, Michael ,  LIDORIKIS, Elefterios ,  VENEZIA, Jo, A. ,  HOEPFNER, Christian

Inventor： ERCHAK, Alexei, A. ,  PANNACIONE, Paul ,  KARLICEK, Robert, F., Jr. ,  LIM, Michael ,  LIDORIKIS, Elefterios ,  VENEZIA, Jo, A. ,  HOEPFNER, Christian

IPC: H01L31/12

CPC classification number: H01L25/0753 ,  H01L33/56 ,  H01L33/62 ,  H01L2224/48091 ,  H01L2224/73265 ,  H01L2924/01012 ,  H01L2924/01046 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/12041 ,  H01L2924/12044 ,  H01L2924/00014 ,  H01L2924/00

Abstract: Light-emitting devices, and related components, processes, systems and methods are disclosed.

Abstract translation:

披露了发光器件及相关部件，工艺，系统和方法。

公开(公告)号：WO2013003569A3

公开(公告)日：2014-05-08

申请号：PCT/US2012044606

申请日：2012-06-28

Applicant: LUMINUS DEVICES INC ,  MCDANIEL DONALD L JR ,  LIM MICHAEL ,  BROWN MICHAEL GREGORY ,  DUNCAN SCOTT W ,  KAZMIERSKI ANDREI ,  PANACCIONE PAUL

Inventor： MCDANIEL DONALD L JR ,  LIM MICHAEL ,  BROWN MICHAEL GREGORY ,  DUNCAN SCOTT W ,  KAZMIERSKI ANDREI ,  PANACCIONE PAUL

IPC: H01L33/00

CPC classification number: H01L33/38 ,  G02B5/005 ,  G02B21/06 ,  G02B21/361 ,  G03B21/2033 ,  G03B21/208 ,  H01L25/0753 ,  H01L33/145 ,  H01L33/20 ,  H01L33/24 ,  H01L33/54 ,  H01L33/58 ,  H01L2924/0002 ,  H01L2924/00

Abstract: The present invention relates to light-emitting diodes (LEDs), and related components, processes, systems, and methods. In certain embodiments, an LED that provides improved optical and thermal efficiency when used in optical systems with a non-rectangular input aperture (e.g., a circular aperture) is described. In some embodiments, the emission surface of the LED and/or an emitter output aperture can be shaped (e.g., in a non-rectangular shape) such that enhanced optical and thermal efficiencies are achieved. In addition, in some embodiments, chip designs and processes that may be employed in order to produce such devices are described.

Abstract translation: 本发明涉及发光二极管（LED）及相关组件，工艺，系统和方法。 在某些实施例中，描述了当在具有非矩形输入孔径（例如圆形孔径）的光学系统中使用时提供改进的光学和热效率的LED。 在一些实施例中，LED和/或发射器输出孔的发射表面可以被成形（例如，以非矩形形状），使得实现增强的光学和热效率。 此外，在一些实施例中，描述了可以用于产生这种装置的芯片设计和工艺。

公开(公告)号：WO2007047469A3

公开(公告)日：2009-04-30

申请号：PCT/US2006040149

申请日：2006-10-13

Applicant: LUMINUS DEVICES INC ,  ERCHAK ALEXEI A ,  LIM MICHAEL ,  VENEZIA JO A ,  NEMCHUK NIKOLAY I ,  KARLICEK ROBERT F JR ,  LIDORIKIS ELEFTERIOS

Inventor： ERCHAK ALEXEI A ,  LIM MICHAEL ,  VENEZIA JO A ,  NEMCHUK NIKOLAY I ,  KARLICEK ROBERT F JR ,  LIDORIKIS ELEFTERIOS

IPC: F21V5/00 ,  F21K99/00 ,  F21V7/20 ,  F21V29/00

CPC classification number: F21V29/89 ,  F21K9/00 ,  F21V29/006 ,  F21V29/20 ,  F21V29/71 ,  F21Y2115/10 ,  G02B6/0028 ,  G02B6/0068 ,  G02B6/0085 ,  H01L24/45 ,  H01L2224/45144 ,  H01L2224/48091 ,  H01L2224/48227 ,  H01L2224/49113 ,  H01L2924/01013 ,  H01L2924/01014 ,  H01L2924/01046 ,  H01L2924/0105 ,  H01L2924/01079 ,  H01L2924/12041 ,  Y10S362/80 ,  H01L2924/00014 ,  H01L2924/00

Abstract: Light-emitting devices can include a package that supports one or more light-emitting die (e.g., light-emitting diode die, laser diode die) and which can ensure mechanically stability, can facilitate electrical and/or thermal coupling with light-emitting die, and can manipulate the manner by which light generated by the die is emitted out of the light-emitting device. The package can also facilitate the integration of the light-emitting devices in various components and systems. For example, suitable packages may facilitate the use of light-emitting devices in components and systems such as light-emitting panel assemblies, LCD back lighting, general lighting, decorative or display lighting, automotive lighting, and other types of lighting components and systems.

Abstract translation: 发光装置可以包括支撑一个或多个发光管芯（例如，发光二极管管芯，激光二极管管芯）并且可以确保机械稳定性的封装，可以促进与发光管芯的电和/或热耦合 并且可以操纵由管芯产生的光从发光器件发出的方式。 该封装还可以促进各种组件和系统中的发光器件的集成。 例如，合适的包装可以促进在诸如发光面板组件，LCD后照明，一般照明，装饰或显示照明，汽车照明和其他类型的照明部件和系统的部件和系统中使用发光装置。

公开(公告)号：WO2009017794A1

公开(公告)日：2009-02-05

申请号：PCT/US2008/009262

申请日：2008-07-30

Applicant: LUMINUS DEVICES, INC. ,  LIM, Michael ,  DOYLE, David ,  POKROVSKIY, Alexander, L. ,  ERCHAK, Alexei, A. ,  TARASCHI, Gianni ,  NEMCHUK, Nikolay, I.

Inventor： LIM, Michael ,  DOYLE, David ,  POKROVSKIY, Alexander, L. ,  ERCHAK, Alexei, A. ,  TARASCHI, Gianni ,  NEMCHUK, Nikolay, I.

IPC: H01J1/62

CPC classification number: G02B6/0061 ,  G02B6/0041 ,  G02B6/0043 ,  G02B6/0068 ,  G02F1/133617

Abstract: Illumination assemblies, components, and related methods are described. An illumination assembly can include at least one solid state light-emitting device, and at least one light guide including a light homogenization region configured to receive light emitted by the solid state light-emitting device and including a light output boundary. The light homogenization region substantially uniformly distributes light outputted over the light output boundary. A wavelength converting material can be disposed within at least a portion of the light homogenization region. In some assemblies, a light extraction region can be configured to receive light from the light output boundary of the light homogenization region, and can have a length along which received light propagates and an emission surface through which light is emitted. The light extraction region can include a wavelength converting material disposed within at least a portion of the light extraction region.

Abstract translation: 描述照明组件，组件和相关方法。 照明组件可以包括至少一个固态发光器件，以及至少一个光导，其包括被配置为接收由固态发光器件发射的光并包括光输出边界的光均质化区域。 光匀化区域基本均匀地分布在光输出边界上输出的光。 波长转换材料可以设置在光均质化区域的至少一部分内。 在一些组件中，光提取区域可以被配置为从光均质化区域的光输出边界接收光，并且可以具有接收光传播的长度和发射光的发射表面。 光提取区域可以包括设置在光提取区域的至少一部分内的波长转换材料。