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公开(公告)号：WO2013052318A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/057155
申请日：2012-09-25
Applicant: THERANOS, INC. , HOLMES, Elizabeth , BALWANI, Sunny , ROY, Joy , FRANKOVICH, John, Kent , FRENZEL, Gary
Inventor： HOLMES, Elizabeth , BALWANI, Sunny , ROY, Joy , FRANKOVICH, John, Kent , FRENZEL, Gary
CPC classification number: G01N35/1065 , G01N35/00 , G01N2035/00326
Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.
Abstract translation: 提供系统和方法用于样品处理。 可以提供能够接收样品并执行样品制备，样品测定和检测步骤中的一种或多种的装置。 该装置可能能够进行多个测定。 该装置可以包括一个或多个可以执行样品制备，样品测定和检测步骤中的一个或多个的模块。 该装置可以能够使用小体积的样品来执行步骤。
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公开(公告)号：WO2006116616A2
公开(公告)日：2006-11-02
申请号：PCT/US2006/016060
申请日：2006-04-26
Applicant: APPLERA CORPORATION , YUE, Min , LIU, David M. , CHIANG, Yuh-Min , YANG, Joon Mo , LEHTO, Dennis , VANN, Charles S. , BEARD, Nigel P. , HARDING, Ian A. , VAN CAMP, John , DROMARETSKY, Alexander , ERMAKOV, Sergey V. , OLDHAM, Mark F. , ROY, Joy , SHARIATI, Maryam , ULMANELLA, Umberto
Inventor： YUE, Min , LIU, David M. , CHIANG, Yuh-Min , YANG, Joon Mo , LEHTO, Dennis , VANN, Charles S. , BEARD, Nigel P. , HARDING, Ian A. , VAN CAMP, John , DROMARETSKY, Alexander , ERMAKOV, Sergey V. , OLDHAM, Mark F. , ROY, Joy , SHARIATI, Maryam , ULMANELLA, Umberto
IPC: G01N33/00
CPC classification number: C12Q1/6806 , B01J2219/00317 , B01J2219/00722 , B01L3/502707 , B01L3/502723 , B01L3/50853 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/041 , B01L2300/048 , B01L2300/0636 , B01L2300/0816 , B01L2300/0829 , B01L2300/0864 , B01L2300/087 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0694 , G01N35/028 , Y10T436/2575
Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.
Abstract translation: 用于多个分析物检测的系统和方法包括用于分配包括衬底的生物样品的系统，其中所述衬底包括多个样品室，用于每个样品室的样品引入通道和用于每个样品室的排气通道。 该系统可以进一步包括包含在每个样品室中并被配置用于进入基底的生物样品的核酸分析的预加载试剂和被配置为与基底接触以密封每个样品室以便基本上防止 每个样品室中包含的样品从每个样品室流出。 底物可以由检测兼容和测定相容的材料构成。
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公开(公告)号：WO2006116616A3
公开(公告)日：2007-09-27
申请号：PCT/US2006016060
申请日：2006-04-26
Applicant: APPLERA CORP , YUE MIN , LIU DAVID M , CHIANG YUH-MIN , YANG JOON MO , LEHTO DENNIS , VANN CHARLES S , BEARD NIGEL P , HARDING IAN A , VAN CAMP JOHN , DROMARETSKY ALEXANDER , ERMAKOV SERGEY V , OLDHAM MARK F , ROY JOY , SHARIATI MARYAM , ULMANELLA UMBERTO
Inventor： YUE MIN , LIU DAVID M , CHIANG YUH-MIN , YANG JOON MO , LEHTO DENNIS , VANN CHARLES S , BEARD NIGEL P , HARDING IAN A , VAN CAMP JOHN , DROMARETSKY ALEXANDER , ERMAKOV SERGEY V , OLDHAM MARK F , ROY JOY , SHARIATI MARYAM , ULMANELLA UMBERTO
IPC: C12M1/38
CPC classification number: C12Q1/6806 , B01J2219/00317 , B01J2219/00722 , B01L3/502707 , B01L3/502723 , B01L3/50853 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/041 , B01L2300/048 , B01L2300/0636 , B01L2300/0816 , B01L2300/0829 , B01L2300/0864 , B01L2300/087 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B01L2400/0694 , G01N35/028 , Y10T436/2575
Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.
Abstract translation: 用于多个分析物检测的系统和方法包括用于分配包括衬底的生物样品的系统，其中所述衬底包括多个样品室，用于每个样品室的样品引入通道和用于每个样品室的排气通道。 该系统可以进一步包括包含在每个样品室中并被配置用于进入基底的生物样品的核酸分析的预加载试剂和被配置为与基底接触以密封每个样品室以便基本上防止 每个样品室中包含的样品从每个样品室流出。 底物可以由检测兼容和测定相容的材料构成。
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公开(公告)号：WO2013043203A2
公开(公告)日：2013-03-28
申请号：PCT/US2011/053188
申请日：2011-09-25
Applicant: THERANOS, INC. , HOLMES, Elizabeth , BALWANI, Sunny , ROY, Joy , FRANKOVICH, John, Kent , FRENZEL, Gary
Inventor： HOLMES, Elizabeth , BALWANI, Sunny , ROY, Joy , FRANKOVICH, John, Kent , FRENZEL, Gary
CPC classification number: G01N35/00 , B01L3/0217 , B01L3/5021 , B01L3/523 , B01L7/52 , B01L9/06 , B01L2200/028 , B01L2200/0631 , B01L2200/0647 , B01L2200/0684 , B01L2200/0689 , B01L2200/082 , B01L2200/141 , B01L2200/16 , B01L2300/044 , B01L2300/0829 , B01L2400/0409 , B01L2400/043 , B01L2400/0677 , G01N35/0092 , G01N2035/00326 , G01N2035/00495
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