公开(公告)号：WO2016044788A2

公开(公告)日：2016-03-24

申请号：PCT/US2015/051054

申请日：2015-09-18

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. ,  HARRINGTON, Joel

Inventor： HARRINGTON, Joel ,  LUMAUIG, Rommel ,  PACETTI, Stephen D. ,  DING, Ni ,  MA, Xiao ,  OBERHAUSER, James ,  MCCOY, Jill ,  ABUNASSAR, Chad J. ,  ESWARAN, Senthil ,  TA, Diem

IPC: A61L31/06

CPC classification number: A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  B29C71/02 ,  B29C2035/046 ,  B29C2035/048 ,  B29C2035/0811 ,  B29C2035/0822 ,  B29C2035/0855 ,  B29C2035/0861 ,  B29C2071/022 ,  B29K2067/046 ,  B29K2995/006 ,  B29L2031/7534 ,  C08G63/08 ,  C08L67/04

Abstract: Method is disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

Abstract translation: 公开了包括热处理支架以在支架从卷曲状态展开到展开状态（例如标称展开直径）时增加支架的径向强度的方法。 当热膨胀超过公称直径时，热处理可进一步保持或增加支架的膨胀能力。

公开(公告)号：WO2017003746A1

公开(公告)日：2017-01-05

申请号：PCT/US2016/038418

申请日：2016-06-20

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： PACETTI, Stephen D. ,  SHEEHY, Alexander J. ,  ABUNASSAR, Chad J.

IPC: A61L31/06 ,  A61L31/10 ,  A61L31/16

CPC classification number: A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61L31/06 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  C08L67/04

Abstract: Stents including a poly(D,L-lactide)(PDLLA)-based scaffold and PDLLA based therapeutic layer are disclosed. The PDLLA based scaffold may be amorphous and may include a primer layer. Methods of applying the PDLLA-based coating to the scaffold are disclosed with solvent processing methods using a solvent blend are also disclosed. Methods of removing residual solvent from a PDLLA-base coating that also condition the scaffold are disclosed. Methods of treating restenosis that release drugs to prevent restenosis without interfering with the natural positive remodeling of a vessel are disclosed.

Abstract translation: 公开了包含基于聚（D，L-丙交酯）（PDLLA）的支架和基于PDLLA的治疗层的支架。 基于PDLLA的支架可以是无定形的，并且可以包括底漆层。 公开了使用溶剂共混物的溶剂处理方法将基于PDLLA的涂层施用于支架的方法。 公开了从处于支架状态的PDLLA基底涂层除去残余溶剂的方法。 公开了治疗释放药物以预防再狭窄而不干扰血管的天然阳性重塑的再狭窄的方法。

公开(公告)号：WO2013074226A1

公开(公告)日：2013-05-23

申请号：PCT/US2012/060059

申请日：2012-10-12

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： ABUNASSAR, Chad J. ,  SCHIKORR, Tanya B. ,  KALVASS, Laura M. ,  ELI, Erik D. ,  TA, Diem U.

IPC: A61F2/06

CPC classification number: A61F2/89 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0037

Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by links. The links between adjacent rings provide axial strength when subjected to longitudinal compressive forces.

Abstract translation: 本发明涉及用于植入体腔（例如冠状动脉，外周动脉或其他体腔）的可扩张支架。 本发明提供一种具有通过连杆连接的多个圆柱形环的血管内支架。 当受到纵向压缩力时，相邻环之间的连接提供轴向强度。

公开(公告)号：WO2014065885A1

公开(公告)日：2014-05-01

申请号：PCT/US2013/036434

申请日：2013-04-12

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： HOSSAINY, Syed ,  ABUNASSAR, Chad J. ,  NGO, Michael Huy ,  ELI, Erik David ,  PRABHU, Santosh V. ,  TROLLSAS, Mikael ,  RAPOZA, Richard

IPC: A61F2/915 ,  A61L31/06 ,  B29C55/26 ,  A61F2/958

CPC classification number: A61F2/915 ,  A61F2/958 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0054 ,  A61F2240/00 ,  A61F2240/008 ,  A61F2250/0071 ,  A61L31/06 ,  B29C55/24 ,  B29C55/26 ,  B29C69/001 ,  B29L2031/753 ,  Y10T29/49 ,  Y10T29/49927 ,  C08L67/04

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架具有当植入在外周血管内时产生较低的晚期管腔损失并且也表现出高的轴向疲劳寿命的结构。 在优选实施例中，支架形成通过连杆互连的环形结构，其中环具有12个冠部，并且至多两个连接相邻环件的连杆。

公开(公告)号：WO2016057402A1

公开(公告)日：2016-04-14

申请号：PCT/US2015/054017

申请日：2015-10-05

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： ABUNASSAR, Chad J.

IPC: A61F2/915

CPC classification number: A61F2/915 ,  A61F2/844 ,  A61F2/89 ,  A61F2002/91525 ,  A61F2002/91566 ,  A61F2002/91583 ,  A61F2210/0004 ,  A61F2210/0057 ,  A61F2230/0004 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0036 ,  A61F2250/0067 ,  A61F2250/0071

Abstract: A stent (10) includes a plurality of rings (20) which form a tubular scaffold. The rings include an elongation mechanism (30) which allows for further expansion of the stent.

Abstract translation: 支架（10）包括形成管状支架的多个环（20）。 环包括允许支架进一步膨胀的伸长机构（30）。

公开(公告)号：WO2015187659A2

公开(公告)日：2015-12-10

申请号：PCT/US2015/033733

申请日：2015-06-02

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： CONSIGNY, Paul ,  RAPOZA, Richard J. ,  HOSSAINY, Syed Faiyaz Ahmed ,  ABUNASSAR, Chad J. ,  SHEEHY, Alexander J. ,  PERKINS, Laura E. ,  PRABHU, Santosh V. ,  CHEONG, Wai-Fung ,  SADARANGANI, Pooja A. ,  PACETTI, Stephen D.

IPC: A61L31/14

CPC classification number: A61L31/148 ,  A61F2/915 ,  A61F2002/91566 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/402 ,  A61L2300/416

Abstract: Methods of treating coronary artery disease (CAD) with bioresorbable stents resulting in reduced angina or non-ischemic chest pain are described. Methods of treatment and devices for treatment of angina and post-procedural chest pain that include anti-angina agents incorporated into the device are disclosed.

Abstract translation: 描述了具有导致心绞痛或非缺血性胸痛减轻的生物可再吸收支架的冠状动脉疾病（CAD）的方法。 公开了治疗方法和治疗心绞痛和手术后胸痛的装置，其包括并入装置中的抗心绞痛药物。

公开(公告)号：WO2014109822A2

公开(公告)日：2014-07-17

申请号：PCT/US2013/068953

申请日：2013-11-07

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS, INC.

Inventor： ABUNASSAR, Chad J.

IPC: A61F2/95

CPC classification number: A61F2/95 ,  A61F2/91 ,  A61F2250/0036

Abstract: A stent for implantation in a body lumen, comprising a plurality of rings, each ring being connected to an adjacent ring by at least one link, each ring including a plurality of peaks and valleys, wherein each peak is connected to an adjacent valley by a strut to provide an undulating pattern within each ring. Further, wherein each of a plurality of the struts comprise a first portion and a second portion; each portion has a thickness that is substantially constant throughout both first and second portions; and each portion has a width that is substantially constant throughout both first and second portions. The first portion is connected to the second portion through a reduced zone positioned at a mid-point of the strut, wherein the reduced zone has a minimum thickness between 30% and 80% of the thickness of the first and second portions.

Abstract translation: 一种用于植入体腔的支架，包括多个环，每个环通过至少一个环连接到相邻的环，每个环包括多个峰和谷，其中每个峰通过一个相邻的谷连接 在每个戒指中提供起伏的图案。 此外，其中多个支柱中的每一个包括第一部分和第二部分; 每个部分具有在第一和第二部分中基本恒定的厚度; 并且每个部分具有在第一和第二部分中基本上恒定的宽度。 第一部分通过位于支柱的中点处的减小区域连接到第二部分，其中减小区域具有在第一和第二部分的厚度的30％至80％之间的最小厚度。