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公开(公告)号：WO2013150496A1
公开(公告)日：2013-10-10
申请号：PCT/IB2013/052736
申请日：2013-04-05
发明人： GUARDIA GIROS, Pablo , RIEDINGER, Andreas , NITTI, Simone , PELLEGRINO, Teresa , MANNA, Liberato , CINGOLANI, Roberto
CPC分类号： C01G49/02 , B82Y30/00 , C01G45/02 , C01G49/0018 , C01G49/0072 , C01G49/06 , C01G49/08 , C01G51/04 , C01P2002/84 , C01P2002/88 , C01P2004/04 , C01P2004/38 , C01P2004/64
摘要： Method for producing iron-based ferrite nanocrystals, where the ferrite is selected from iron oxides and iron/cobalt or iron/manganese mixed salts, by thermal decomposition of one or more precursors of the ferrite, consisting of an organic salt of the metal or metals constituting the ferrite of interest, comprising the operation of heating a solution comprising said precursor(s) in the presence of a surfactant and of a non-aqueous organic solvent comprising an ether, at temperature sufficient to cause thermal decomposition of said precursor, characterized in that the solvent further comprises a saturated or unsaturated, linear or branched aliphatic hydrocarbon, liquid at temperatures above 45°C and having a boiling point above the boiling point of the ethereal solvent.
摘要翻译： 铁氧体铁氧体纳米晶体的制造方法，铁氧体选自氧化铁和铁/钴或铁/锰混合盐，通过热分解一种或多种铁素体前体，由金属或金属的有机盐组成 构成感兴趣的铁氧体，包括在足以引起所述前体热分解的温度下，在表面活性剂和包含醚的非水有机溶剂的存在下加热包含所述前体的溶液的操作，其特征在于 溶剂在高于45℃的温度下进一步包含饱和或不饱和的直链或支链脂族烃，其沸点高于醚类溶剂的沸点。
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2.发明申请
公开(公告)号：WO2012077043A3
公开(公告)日：2012-06-14
申请号：PCT/IB2011/055479
申请日：2011-12-06
申请人： FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA , MAIORANO, Gabriele , RIZZELLO, Loris , SANGARU, Shiv Shankar , CINGOLANI, Roberto , POMPA, Pier Paolo
发明人： MAIORANO, Gabriele , RIZZELLO, Loris , SANGARU, Shiv Shankar , CINGOLANI, Roberto , POMPA, Pier Paolo
摘要： A method of synthesizing branched gold nanoparticles is described, starting from an aqueous solution of gold nanoparticle spherical seeds, which is subjected to a growth treatment with an aqueous solution comprising hydroxylamine or a salt thereof as a reducing agent and 4-(2-hydroxyethyl)-l-piperazineethanesulfonic acid (HEPES) as an agent that directs the shape of the nanostructure, and by subsequent addition of an aqueous solution of chloroauric acid (HAuCl4). The structural features and the properties of the branched gold nanoparticles obtained by the method of the invention are also described.
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公开(公告)号：WO2018138677A1
公开(公告)日：2018-08-02
申请号：PCT/IB2018/050477
申请日：2018-01-26
发明人： PELLEGRINO, Teresa , MAI, Thanh Binh , BARTHEL, Markus Joachim , BALAKRISHNAN, Preethi Bala , KAKWERE, Hamilton , CINGOLANI, Roberto
摘要： Process for preparing magnetic nanoparticles coated with a thermo- or Ph-responsive polymer, characterized in that it comprises the radical polymerization of a monomer or co-monomers susceptible of forming a thermo-polymer or Ph-responsive copolymer in a solution including magnetic nanoparticles functionalized at their surface with a polymerization initiator of formula (I): wherein: R 3 is hydrogen or hydroxyl, Hal is a halogen selected from bromine, chlorine and iodine, m is an integer from 1 to 10, preferably from 1 to 3, and R 1 and R 2 , independently of one another, are selected from hydrogen, methyl and phenyl. The coated particles are useful, particularly as carriers of a drug in therapeutic treatments by hyperthermia and/or in situ release of the drug.
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公开(公告)号：WO2015004593A3
公开(公告)日：2015-01-15
申请号：PCT/IB2014/062919
申请日：2014-07-07
摘要： Process for producing a hydrophobic composite bioelastomer, comprising a cross-linked bioelastomer matrix in which an organic phase is dispersed, comprising the reaction of cross-linking of a hydroxyl-terminated polysiloxane with a silane coupling agent, comprising an acetoxysilane, to obtain a cross-linked polysiloxane with release of acetic acid. The reaction of cross-linking is carried out in the presence of starch to cause at least partial in situ acetylation by the acetic acid released from said starch that is incorporated in the cross-linked bioelastomer matrix.
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公开(公告)号：WO2014002076A1
公开(公告)日：2014-01-03
申请号：PCT/IB2013/055337
申请日：2013-06-28
CPC分类号： H01G9/2031 , G02F1/155 , G02F2001/1555 , G02F2202/04 , G02F2203/68 , H01G9/2022 , H01M4/8647 , H01M14/005 , Y02E10/542 , Y02P70/521
摘要： A photovoltachromic device (50) having a photoelectrode (86) and a counterelectrode (66), the counterelectrode including an electrochromic region (70) and a catalytic region (72) that are physically separate. The electrochromic region and the catalytic region are interdigitated.
摘要翻译： 具有光电极（86）和反电极（66）的光电装置（50），反电极包括物理分离的电致变色区域（70）和催化区域（72）。 电致变色区域和催化区域是交错的。
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6.发明申请ORDERED SUPERSTRUCTURES OF OCTAPOD - SHAPED NANOCRYSTALS, THEIR PROCESS OF FABRICATION AND USE THEREOF 审中-公开OCTAPOD - 形状纳米晶体的订购超导结构及其制造及其应用
公开(公告)号：WO2013017166A1
公开(公告)日：2013-02-07
申请号：PCT/EP2011/063304
申请日：2011-08-02
申请人： FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA , MISZTA, Karol , DORFS, Dirk , BERTONI, Giovanni , MANNA, Liberato , BRESCIA, Rosaria , MARRAS, Sergio , CINGOLANI, Roberto , KRAHNE, Roman , ZHANG, Yang , QIAN, Fen
发明人： MISZTA, Karol , DORFS, Dirk , BERTONI, Giovanni , MANNA, Liberato , BRESCIA, Rosaria , MARRAS, Sergio , CINGOLANI, Roberto , KRAHNE, Roman , ZHANG, Yang , QIAN, Fen
IPC分类号： C30B29/60 , C30B7/00 , C09K11/02 , C09K11/56 , C09K11/88 , H01L21/02 , H01L31/0352 , C30B5/00
CPC分类号： H01L31/0352 , B82Y10/00 , B82Y40/00 , C30B5/00 , C30B29/60 , H01L21/02595 , H01L29/0665 , H01L29/127 , H01L29/151 , Y10T428/24372
摘要： This invention relates to the controlled realization of ordered superstructures of octapod-shaped colloidal nanocrystals, formed either in the liquid phase or on a solid substrate. These structures can be applied in many fields of technology.
摘要翻译： 本发明涉及在液相或固体基质上形成的八脚形胶体纳米晶体的有序上层结构的受控实现。 这些结构可以应用于许多技术领域。
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7.发明申请
公开(公告)号：WO2012077043A4
公开(公告)日：2012-06-14
申请号：PCT/IB2011/055479
申请日：2011-12-06
申请人： FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA , MAIORANO, Gabriele , RIZZELLO, Loris , SANGARU, Shiv Shankar , CINGOLANI, Roberto , POMPA, Pier Paolo
发明人： MAIORANO, Gabriele , RIZZELLO, Loris , SANGARU, Shiv Shankar , CINGOLANI, Roberto , POMPA, Pier Paolo
摘要： A method of synthesizing branched gold nanoparticles is described, starting from an aqueous solution of gold nanoparticle spherical seeds, which is subjected to a growth treatment with an aqueous solution comprising hydroxylamine or a salt thereof as a reducing agent and 4-(2-hydroxyethyl)-l-piperazineethanesulfonic acid (HEPES) as an agent that directs the shape of the nanostructure, and by subsequent addition of an aqueous solution of chloroauric acid (HAuCl4). The structural features and the properties of the branched gold nanoparticles obtained by the method of the invention are also described.
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8.发明申请ELECTRICAL TRANSDUCTION METHOD AND DEVICE FOR THE DETECTION OF BIORECOGNITION EVENTS IN BIOMOLECULAR INTERACTION PROCESSES FOR GENOME/PROTEOME ANALYSIS 审中-公开用于检测生物分子生物活性的电传递方法和装置用于基因组/保护分析的生物分子相互作用过程
公开(公告)号：WO2008139421A2
公开(公告)日：2008-11-20
申请号：PCT/IB2008/051900
申请日：2008-05-14
申请人： CONSIGLIO NAZIONALE DELLE RICERCHE - INFM ISTITUTO NAZIONALE PER LA FISICA DELLA MATERIA , FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA , MARUCCIO, Giuseppe , PRIMICERI, Elisabetta , MARZO, Pasquale , ARIMA, Valentina , KRAHNE, Roman , PELLEGRINO, Teresa , DELLA TORRE, Antonio , CALABI, Franco , CINGOLANI, Roberto , RINALDI, Rosaria
发明人： MARUCCIO, Giuseppe , PRIMICERI, Elisabetta , MARZO, Pasquale , ARIMA, Valentina , KRAHNE, Roman , PELLEGRINO, Teresa , DELLA TORRE, Antonio , CALABI, Franco , CINGOLANI, Roberto , RINALDI, Rosaria
IPC分类号： G01N33/543
CPC分类号： H01L51/0595 , B82Y5/00 , B82Y10/00 , C12Q1/6825 , G01N27/3278 , G01N33/5438 , G01N33/587 , H01L51/0093 , C12Q2563/155 , C12Q2563/137 , C12Q2563/113 , C12Q2545/114
摘要： A method is described for detecting biorecognition events in biomolecular interaction processes, including the provision, on at least one biorecognition site, of molecular probes (P) adapted to interact with target molecular species (T) which are coupled to conductive nanoparticles (NP), in which the probes (P) are associated with a nanojunction transducer device (12) comprising a pair of conductive electrodes (22, 24) separated by a nanometric gap of the same order of magnitude as the dimensions of said conductive nanoparticles (NP), adapted to detect a condition of coupling between at least one molecular probe (P) and a specimen of a target species (T) which interact with each other. A biorecognition event includes the coupling of a probe (P) to at least one specimen of the target species (T) and results in the positioning of the conductive nanoparticle (NP) coupled to the target species (T) (by being directly conjugated with the latter or with a signal molecule which can interact with it) between the electrodes (22, 24) of the nanojunction device (12), with the consequent creation of a conductive path between the electrodes. The occurrence of biorecognition events is evaluated according to the intensity of the current which is made to flow between the electrodes (22, 24) of the nanojunction device (12) by the application of a potential difference.
摘要翻译： 描述了用于检测生物分子相互作用过程中的生物识别事件的方法，包括在至少一个生物识别位点上提供适于与与导电纳米颗粒（NP）偶联的靶分子物质（T）相互作用的分子探针（P） 其中所述探针（P）与包括由与所述导电纳米颗粒（NP）的尺寸相同数量级的纳米间隙分开的一对导电电极（22,24））的纳米结转换器装置（12）相关联， 适于检测至少一个分子探针（P）和彼此相互作用的目标物种（T）的样品之间的耦合条件。 生物识别事件包括探针（P）与目标物种（T）的至少一个样品的偶联，并导致与靶物种（T）偶联的导电纳米颗粒（NP）的定位（通过直接与 后者或具有与其相互作用的信号分子）在纳米结装置（12）的电极（22,24）之间，从而在电极之间产生导电路径。 根据通过施加电位差在纳米结装置（12）的电极（22,24）之间流动的电流的强度来评价生物识别事件的发生。
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9.发明申请PACKAGING MATERIAL WITH BARRIER PROPERTIES TO THE MIGRATION OF MINERAL OILS AND PROCESS PREPARATION THEREOF 审中-公开包装材料具有阻挡矿物转移的特性及其制备方法
公开(公告)号：WO2015092714A1
公开(公告)日：2015-06-25
申请号：PCT/IB2014/067030
申请日：2014-12-17
发明人： ATHANASIOU, Athanasia , PAUL, Uttam C. , MELE, Elisa , FRAGOULI, Despina , BAYER, Ilker S. , CINGOLANI, Roberto
IPC分类号： D21H27/10 , D21H19/56 , D21H19/58 , D21H19/82 , D21H21/16 , B65D65/42 , D21H11/14 , B32B27/10 , B32B27/30 , B32B27/32 , B32B29/00
摘要： Process for inhibiting the migration to the exterior of mineral oils consisting of saturated and/or aromatic hydrocarbons and/or of their volatile components, having from 10 to 25 carbon atoms included in packaging materials comprising recycled cellulosic fibres, characterized in that it comprises the operations of surface treatment of said packaging material to form a first polymer coating comprising an acrylic polymer, in contact with said fibres, and a second surface treatment by application of a second polymer coating comprising a cyclic olefin polymer on said first coating, where the total amount of acrylic polymer and of cyclic olefin polymer of the first and second coating is between 15 and 50 g/m 2 .
摘要翻译： 用于抑制由包含再循环纤维素纤维的包装材料中包含10至25个碳原子的饱和和/或芳族烃和/或其挥发性组分组成的矿物油的迁移过程，其特征在于其包括操作 对所述包装材料进行表面处理以形成包含与所述纤维接触的丙烯酸类聚合物的第一聚合物涂层和通过在所述第一涂层上施加包含环烯烃聚合物的第二聚合物涂层进行第二表面处理，其中总量 的丙烯酸类聚合物和第一和第二涂层的环烯烃聚合物为15-50g / m 2。
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10.发明申请
公开(公告)号：WO2014027323A8
公开(公告)日：2014-02-20
申请号：PCT/IB2013/056645
申请日：2013-08-14
IPC分类号： G01N13/00
摘要： A device (1) is described for determining the dissolution kinetics of colloidal nanoparticles (2) in respective derivation ions (3) in a solution (4), which comprises a dissolution compartment (5) containing the solution (4), and feedable with the colloidal nanoparticles (2); an analysis compartment (6) separate from the dissolution compartment (5); a fixed filtering membrane (7) which separates the dissolution compartment (5) from the analysis compartment (6), is selectively permeable to the derivation ion (3) and is adapted to filter the solution (4); compressing means (8) to induce passage of the solution (4) from the dissolution compartment (5) to the analysis compartment (6) through the filtering membrane (7); a determination device (9) for determining the quantity of the derivation ion (3); the device furthermore comprises mixing means (10) associated to the dissolution compartment (5) and distinct from the compressing means (8) and the filtering membrane (7) has pores of size smaller than 10 nm. Relative determination methods for determining the dissolution kinetics and the toxicity of colloidal nanoparticles (2), are also described.
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