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1.发明申请PROMOTION OF HEALING OF INTESTINAL MUCOSA USING PROLINE, SERINE AND THREONINE 审中-公开促进精油，丝氨酸和精神分裂素治疗肠胃粘膜炎
公开(公告)号：WO2016116585A1
公开(公告)日：2016-07-28
申请号：PCT/EP2016/051287
申请日：2016-01-22
Applicant: NESTEC S.A.
Inventor： FAURE, Magali , BLUM-SPERISEN, Stéphanie , BOSCO, Mohamed Nabil , BRAHMBHATT, Viral , BREUILLE, Denis
IPC: A61K31/198 , A61P29/00 , A61P19/00
CPC classification number: A61K31/401 , A23L33/175 , A23V2002/00 , A61K31/198
Abstract: Methods and compositions are provided that use proline, serine and threonine to promote healing of the intestinal mucosa. A therapeutically effective amount of proline, serine and threonine is administered to an individual in need thereof, for example a human or other mammal, such as an individual that has damaged intestinal mucosa. The methods and compositions can promote mucosal healing, restore gut barrier function, repair intestinal epithelial cells, promote protection of the colonic epithelium, and/or promote the replenishment of goblet cells in the intestinal and colonic mucosa.
Abstract translation: 提供了使用脯氨酸，丝氨酸和苏氨酸促进肠粘膜愈合的方法和组合物。 向有需要的个体施用治疗有效量的脯氨酸，丝氨酸和苏氨酸，例如人或其它哺乳动物，例如具有损伤的肠粘膜的个体。 方法和组合物可以促进粘膜愈合，恢复肠屏障功能，修复肠上皮细胞，促进结肠上皮的保护和/或促进肠和结肠粘膜中杯状细胞的补充。
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2.发明申请FIBER AND PROBIOTICS FOR REDUCING INTESTINAL SYMPTOMS RELATED TO CHRONIC STRESS 审中-公开用于减少与慢性应激相关的症状的纤维和生物学
公开(公告)号：WO2012089784A1
公开(公告)日：2012-07-05
申请号：PCT/EP2011/074189
申请日：2011-12-28
Applicant: NESTEC S.A. , FAURE, Magali , BERGONZELLI DEGONDA, Gabriela
Inventor： FAURE, Magali , BERGONZELLI DEGONDA, Gabriela
CPC classification number: A61K35/747 , A23L5/00 , A23L7/00 , A23L29/30 , A23L29/35 , A23L33/125 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K2300/00 , A23V2200/3202 , A23V2200/3204 , A23V2250/284 , A23V2250/5114
Abstract: The present invention provides a composition that is suitable to reduce the impact of chronic stress on intestinal symptoms and/or conditions. The composition comprises a probiotic microorganism and soluble fiber. Preferably, the soluble fiber is a low viscosity soluble fiber. The composition is in particular suitable to alleviate abdominal discomfort, abdominal pain, abdominal cramps, and bowel movement disturbances; in as far as these conditions and symptoms are associated with stress.
Abstract translation: 本发明提供了适合于减少慢性应激对肠道症状和/或病症的影响的组合物。 组合物包含益生菌微生物和可溶性纤维。 优选地，可溶性纤维是低粘度可溶性纤维。 该组合物特别适合于缓解腹部不适，腹痛，腹部痉挛和排便紊乱; 只要这些条件和症状与压力相关。
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3.发明申请
公开(公告)号：WO2005039318A1
公开(公告)日：2005-05-06
申请号：PCT/EP2004/011539
申请日：2004-10-14
Applicant: NESTEC S.A. , SCHIFFRIN, Eduardo , BREUILLÉ, Denis , BLUM-SPERISEN, Stéphanie , DONNET-HUGHES, Anne , FAURE, Magali , ROESSLE, Claudia , TURINI, Marco, Enrico
Inventor： SCHIFFRIN, Eduardo , BREUILLÉ, Denis , BLUM-SPERISEN, Stéphanie , DONNET-HUGHES, Anne , FAURE, Magali , ROESSLE, Claudia , TURINI, Marco, Enrico
IPC: A23L1/29
Abstract: The present invention relates to a nutritional composition suitable for patients undergoing chemotherapy and/or radiation such as cancer patients. The composition, which may be in powder or liquid form, comprises casein and whey proteins, TGF-β and free glutamine.
Abstract translation: 本发明涉及适合于接受化疗和/或放射的患者（例如癌症患者）的营养组合物。 可以是粉末或液体形式的组合物包含酪蛋白和乳清蛋白，TGF-β和游离谷氨酰胺。
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公开(公告)号：WO2016116580A1
公开(公告)日：2016-07-28
申请号：PCT/EP2016/051275
申请日：2016-01-22
Applicant: NESTEC S.A.
Inventor： BLUM-SPERISEN, Stéphanie , FAURE, Magali , BREUILLE, Denis , CHUANG, Emil
IPC: A61K31/198 , A61K31/401 , A61K38/18 , A61K31/70 , A61K31/715 , A61K31/718 , A61K35/20 , A61K31/202 , A61P29/00 , A61K31/20 , A23L2/00
CPC classification number: A61K31/401 , A23L2/00 , A23V2250/064 , A23V2250/0642 , A23V2250/0648 , A23V2250/1868 , A23V2250/28 , A23V2250/50 , A23V2250/54252 , A61K31/198 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/70 , A61K31/715 , A61K31/718 , A61K35/20 , A61K38/1841 , A61K2300/00
Abstract: Compositions and methods are provided that are useful in the treatment of inflammatory bowel disease (IBD) patients. The Compositions and methods are suitable in the prevention or postponement of a relapse in inflammatory bowel disease patients.
Abstract translation: 提供了可用于治疗炎性肠病（IBD）患者的组合物和方法。 组合物和方法适用于预防或推迟炎症性肠病患者复发。
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公开(公告)号：WO2015075257A1
公开(公告)日：2015-05-28
申请号：PCT/EP2014/075515
申请日：2014-11-25
Applicant: NESTEC S.A.
Inventor： BERGONZELLI DEGONDA, Gabriela , DONATO-CAPEL, Laurence , FAURE, Magali , IDIEDER, Benoit , LABBE, David Philippe , BRICKELL, Oliver Robert
IPC: A23L1/303 , A23L1/305 , A23L1/19 , A23L1/29 , A61P1/04 , A23C9/15 , A23C9/13 , A23C11/00 , A23L2/385 , A23L2/52 , A23L2/56 , A23L2/66
CPC classification number: A23L2/66 , A23C9/1512 , A23C9/1522 , A23C9/158 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2200/32 , A23V2200/3204 , A23V2250/1578 , A23V2250/5424 , A23V2250/54252 , A23V2250/702 , A23V2250/71
Abstract: The invention relates generally to the field of maintaining good health and wellbeing. A composition is provided that can be used to alleviate or prevent gastric discomfort, and which may comprise milk SNF, milk fat, demineralized whey powder, dibasic sodium phosphate, monobasic sodium phosphate, and a cooling agent. In particular, the composition is shelf stable at ambient temperatures, stable in liquid products, and can be used to alleviate or prevent gastritis, its symptoms and/or gastritis-like symptoms.
Abstract translation: 本发明一般涉及维持身体健康和福祉的领域。 提供了可用于缓解或预防胃不适的组合物，其可以包括牛奶SNF，乳脂肪，软化乳清粉末，磷酸氢二钠，磷酸二氢钠和冷却剂。 特别地，组合物在环境温度下是稳定的，在液体产品中稳定，并且可用于缓解或预防胃炎，其症状和/或胃炎样症状。
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Patent Agency Ranking
公开(公告)号：WO2011037712A2
公开(公告)日：2011-03-31
申请号：PCT/US2010/046301
申请日：2010-08-23
Applicant: GREENBERG, Norman Alan , MCLEAN, Peter Geoffrey , FAURE, Magali , NESTEC S.A.
Inventor： GREENBERG, Norman Alan , MCLEAN, Peter Geoffrey , FAURE, Magali
IPC: A23L1/30
CPC classification number: A23L33/175 , A23L33/13 , A23V2002/00 , A23V2250/0646 , A23V2200/31 , A23V2200/32
Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including theanine and one or more exogenous nucleotides. The nutritional compositions can be specifically used to treat functional bowel disorders, including inflammatory bowel syndrome.
Abstract translation: 提供营养组合物和制备和使用营养组合物的方法。 在一般的实施方案中，本公开提供了包含茶氨酸和一种或多种外源核苷酸的营养组合物。 营养组合物可以专门用于治疗功能性肠病，包括炎性肠综合症。
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7.发明申请
公开(公告)号：WO2016116583A1
公开(公告)日：2016-07-28
申请号：PCT/EP2016/051283
申请日：2016-01-22
Applicant: NESTEC S.A.
IPC: G01N33/50
CPC classification number: G01N33/5091 , A23L33/10 , A23L33/40 , A23V2002/00 , A61K45/06 , G01N33/50 , G01N33/5308 , G01N33/6803 , G01N33/6806 , G01N33/6848 , G01N33/6893 , G01N33/82 , G01N33/84 , G01N33/92 , G01N2333/90254 , G01N2800/02 , G01N2800/065 , G01N2800/7009
Abstract: The present invention relates to a method for determining the distinctive nutritional requirements of a patient with specific nutritional needs and providing a composition meeting the distinctive nutritional requirements of said patient.
Abstract translation: 本发明涉及一种用于确定具有特定营养需要的患者的独特营养需求并提供满足所述患者的独特营养需求的组合物的方法。
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8.发明申请A NUTRITIONAL COMPOSITION COMPRISING FIBER AND PROBIOTICS FOR REDUCING STRESS-RELATED INTESTINAL SYMPTOMS 审中-公开包含纤维和减少与应激相关的症状的PROBIOTICS的营养组合物
公开(公告)号：WO2012089783A1
公开(公告)日：2012-07-05
申请号：PCT/EP2011/074188
申请日：2011-12-28
Applicant: NESTEC S.A. , FAURE, Magali , BERGONZELLI DEGONDA, Gabriela
Inventor： FAURE, Magali , BERGONZELLI DEGONDA, Gabriela
IPC: A61K35/74 , A61K31/702 , A61P1/14 , A23L1/302 , A23L1/304 , A23L1/308 , A23L1/03 , A23L1/305 , A61K38/01
CPC classification number: A23L1/3014 , A23L33/10 , A23L33/135 , A23L33/15 , A23L33/16 , A23L33/19 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K35/747 , A61K38/018 , A23V2200/32 , A23V2200/3202 , A23V2200/3204 , A23V2250/156 , A23V2250/1842 , A23V2250/284 , A23V2250/5114 , A23V2250/54246 , A23V2250/54252 , A23V2250/612 , A23V2250/70
Abstract: The present invention provides a nutritional composition that is suitable to reduce the impact of stress on intestinal symptoms and/or conditions. The composition comprises one or more selected from a probiotic microorganism,one or more inactive probiotic, and one or more culture medium of one or more probiotic; and soluble fiber, and possibly other ingredients such as a milk ingredient, a source of carbohydrates and a source of protein. Preferably, the soluble fiber is a low viscosity soluble fiber. The composition is in particular suitable to alleviate abdominal discomfort, abdominal pain, abdominal cramps, and bowel movement disturbances, such as abdominal bloating, flatulence, in particular in as far as these conditions and symptoms are associated with stress.
Abstract translation: 本发明提供了适合于减轻压力对肠道症状和/或病症的影响的营养组合物。 组合物包含选自益生菌微生物，一种或多种无活性益生菌和一种或多种益生菌的一种或多种培养基中的一种或多种; 和可溶性纤维，以及可能的其它成分如牛奶成分，碳水化合物源和蛋白质来源。 优选地，可溶性纤维是低粘度可溶性纤维。 该组合物特别适合于减轻腹部不适，腹痛，腹部痉挛和肠运动障碍，例如腹部腹胀，肠胃气胀，特别是在这些病症和症状与压力相关的情况下。
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9.发明申请LACTOFERRIN AND BRAIN HEALTH AND PROTECTION IN ADULTS 审中-公开LACTOFERRIN和BRAIN HEALTH AND PROTECTION IN ADULTS
公开(公告)号：WO2010130646A1
公开(公告)日：2010-11-18
申请号：PCT/EP2010/056241
申请日：2010-05-07
Applicant: NESTEC S.A. , WANG, Bing , FAURE, Magali , SCHMITT, Jeroen
Inventor： WANG, Bing , FAURE, Magali , SCHMITT, Jeroen
CPC classification number: A61K38/40 , A23L2/66 , A23L33/17 , A23V2002/00 , A61K35/20 , A23V2200/322 , A23V2250/54248 , A23V2250/54252 , A23V2250/1882
Abstract: The present invention relates generally to the field of brain health, brain protection, maintenance of cognitive function, prevention of cognitive decline and cognitive disorders. Neuronal cells in the brain can be protected. Also cognitive performance can be increased.
Abstract translation: 本发明一般涉及脑健康，脑保护，认知功能维持，认知衰退预防和认知障碍领域。 大脑中的神经元细胞可以被保护。 也可以增加认知能力。
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10.发明申请COMBINATION OF (A) A PHOSPHOINOSITIDE 3-KINASE INHIBITOR AND (B) AN ANTIDIABETIC COMPOUND FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES 审中-公开（A）磷酸三磷酸激酶抑制剂的组合和（B）用于治疗增殖性疾病的抗生素化合物
公开(公告)号：WO2010130644A1
公开(公告)日：2010-11-18
申请号：PCT/EP2010/056238
申请日：2010-05-07
Applicant: NESTEC S.A. , FAURE, Magali , WANG, Bing , SCHMITT, Jeroen
Inventor： FAURE, Magali , WANG, Bing , SCHMITT, Jeroen
CPC classification number: A61K38/40 , A23L2/66 , A23L33/19 , A23L33/40 , A23V2002/00 , A61K35/20 , A23V2250/54248 , A23V2200/322 , A23V2200/32
Abstract: The present invention relates generally to the field of neuronal health and neuronal protection. One embodiment of the present invention relates to a composition that can be used for the protection of the enteric nervous system from neurodegeneration. Disorders linked to an impaired enteric nervous system can be treated or prevented by the administration of lactoferrin containing compositions according to the present invention.
Abstract translation: 本发明一般涉及神经元健康和神经元保护领域。 本发明的一个实施方案涉及可用于保护肠神经系统免于神经变性的组合物。 可以通过施用根据本发明的含有乳铁蛋白的组合物来治疗或预防与受损的肠神经系统相关的疾病。
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