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    FIXATION MEMBER ASSEMBLY HAVING BI-DIRECTIONAL CONTROLLED DRUG RELEASE
    1.
    发明申请
    FIXATION MEMBER ASSEMBLY HAVING BI-DIRECTIONAL CONTROLLED DRUG RELEASE 审中-公开

    公开(公告)号：WO2019152417A1

    公开(公告)日：2019-08-08

    申请号：PCT/US2019/015674

    申请日：2019-01-29

    申请人： MEDTRONIC, INC.

    发明人： YANG, Zhongping ,  ASLESON, Andrea ,  MARTINEZ, Gonzalo ,  MCVENES, Rick D. ,  STORMENT, Christopher W.

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0575 ,  A61N1/365 ,  A61N1/37512 ,  A61N1/3756

    摘要： An implantable medical lead having an elongated lead body extending from a proximal end to a distal end, at least one conductor extending within the lead body from the proximal end to the distal end, and a fixation member having a proximal end and a distal end, the proximal end of the electrode configured to be electrically coupled to the distal end of the lead body. The fixation member includes a first delivery port and second delivery port for releasing a therapeutic agent from the fixation member to tissue of a patient, wherein the first delivery port is positioned along the proximal end of the fixation member to deliver the therapeutic agent to endothelial cells along an endothelial layer of tissue, and the second delivery port is positioned along the distal end of the fixation member and spaced a distance from the first delivery port.

    SEALED PACKAGE AND METHOD OF FORMING SAME
    3.
    发明申请
    SEALED PACKAGE AND METHOD OF FORMING SAME 审中-公开
    密封包装及其形成方法

    公开(公告)号：WO2017112356A1

    公开(公告)日：2017-06-29

    申请号：PCT/US2016/063859

    申请日：2016-11-28

    申请人： MEDTRONIC, INC.

    发明人： RUBEN, David, A. ,  SCHMIDT, Craig, L.

    IPC分类号： A61N1/372 ,  A61N1/375

    CPC分类号： A61B5/686 ,  A61B5/0245 ,  A61N1/05 ,  A61N1/372 ,  A61N1/37512 ,  A61N1/3754 ,  A61N2001/37294 ,  H05K1/115 ,  H05K1/183 ,  H05K3/0017 ,  H05K3/32 ,  H05K3/4038 ,  H05K5/0247 ,  H05K5/03 ,  H05K5/066 ,  H05K5/069 ,  H05K2201/09036

    摘要： Various embodiments of a sealed package and a method of forming such package are disclosed. The package can include a non-conductive substrate that includes a cavity disposed in a first major surface. A cover layer can be disposed over the cavity and attached to the first major surface of the non-conductive substrate to form a sealed enclosure. The sealed package can also include a feedthrough that includes a via between a recessed surface of the cavity and a second major surface of the substrate, and a conductive material disposed in the via. An external contact can be disposed over the via on the second major surface of the non-conductive substrate, where the external contact is electrically connected to the conductive material disposed in the via. The sealed package can also include an electronic device disposed within the sealed enclosure that is electrically connected to the external contact.

    摘要翻译： 公开了密封包装的各种实施例和形成这种包装的方法。 该封装可以包括非导电衬底，该非导电衬底包括设置在第一主表面中的空腔。 覆盖层可以设置在空腔上并且附着到非导电基板的第一主表面以形成密封外壳。 密封封装还可以包括馈通件，该馈通件包括在腔的凹陷表面和基板的第二主表面之间的通路以及设置在通路中的导电材料。 可以在非导电衬底的第二主表面上的通孔上设置外部触点，其中外部触点电连接到设置在通孔中的导电材料。 密封包装还可以包括设置在密封外壳内的电子设备，其与外部触点电连接。

    SUBCUTANEOUS DEFIBRILLATION
    9.
    发明申请
    SUBCUTANEOUS DEFIBRILLATION 审中-公开
    皮下去纤颤

    公开(公告)号：WO2017196477A1

    公开(公告)日：2017-11-16

    申请号：PCT/US2017/026751

    申请日：2017-04-10

    申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

    发明人： CATANZARO, John, N.

    IPC分类号： A61N1/05 ,  A61N1/372 ,  A61N1/375 ,  A61N1/39

    CPC分类号： A61N1/375 ,  A61N1/0504 ,  A61N1/0563 ,  A61N1/37512 ,  A61N1/3756 ,  A61N1/3918 ,  A61N1/3956

    摘要： Cardioversion or defibrillation of the heart is carried out by passing electrical energy through the heart. An electrical energy storage device, such as a battery and capacitor, are connected to an electronic processor. The energy storage device and the electronic processor are sized to be implantable within the body of the patient. Two leads are subcutaneously implanted and connected to the energy storage device under control of the processor. An electrode is connected to each lead, and are also subcutaneously implanted, the first able proximate the heart and an anterior portion of the ribcage in the patient's chest, and the second proximate the heart and a posterior portion of the ribcage in the patients back. Sensors transmit information to the processor relating to heart function, and under control of software, the processor causes the electrodes to be energized to restore normal heart function.

    摘要翻译： 心脏的心脏复律或除颤通过使电能通过心脏来进行。 诸如电池和电容器的电能存储装置连接到电子处理器。 能量存储装置和电子处理器的尺寸设定为可植入患者体内。 在处理器的控制下，两根导线皮下植入并连接到能量存储装置。 电极连接到每条引线，并且还被皮下植入，第一个能够靠近心脏并且胸腔的前部位于患者的胸腔中，并且第二个靠近心脏和患者背部的胸腔的后部。 传感器向处理器传输与心脏功能有关的信息，并且在软件的控制下，处理器使电极通电以恢复正常的心脏功能。

    FLEXIBLE SEMI-HERMETIC IMPLANTABLE MEDICAL DEVICE STRUCTURE
    10.
    发明申请
    FLEXIBLE SEMI-HERMETIC IMPLANTABLE MEDICAL DEVICE STRUCTURE 审中-公开
    灵活的半密封可植入医疗器械结构

    公开(公告)号：WO2017191507A1

    公开(公告)日：2017-11-09

    申请号：PCT/IB2017/000595

    申请日：2017-05-03

    申请人： NEWPACE LTD.

    发明人： SHMARAK, lTZHAK ,  BRODER, Avraham ,  MOCHA, Mordechay ,  STROMMER, Gera ,  BELSKY, Ziv ,  SETER, Dan ,  BAR OR, Jonathan

    IPC分类号： A61N1/08 ,  A61N1/02 ,  A61N1/05 ,  A61N1/36

    CPC分类号： A61N1/3752 ,  A61N1/056 ,  A61N1/08 ,  A61N1/37512 ,  A61N1/3968

    摘要： Flexible semi-hermetic implantable medical device (IMD) structure, including a flexible device body, at least one flexible lead and at least one respective transition unit, for respectively coupling each flexible lead to the flexible device body, the flexible device body including a plurality of hermetically sealed components, at least one electrical cable harness and an external flexible polymer structure, each one of the hermetically sealed components including at least one hermetically sealed electrical connection and at least some of the hermetically sealed components including at least one separation dome, the electrical cable harness for electrically and mechanically coupling the plurality of hermetically sealed components together and the external flexible polymer structure for encapsulating the hermetically sealed components, the electrical cable harness and the respective transition unit.

    摘要翻译： 包括柔性装置本体，至少一个柔性引线和至少一个相应的过渡单元的柔性半气密性可植入医疗装置（IMD）结构，用于将每个柔性引线分别连接到柔性装置本体 ，所述柔性装置主体包括多个密封部件，至少一个电缆线束和外部柔性聚合物结构，所述密封部件中的每一个包括至少一个气密密封的电连接部，并且至少一些所述密封部件 包括至少一个分离圆顶，用于将多个气密密封部件电气地和机械地连接在一起的电缆线束以及用于包封气密密封部件，电缆线束和相应的过渡单元的外部柔性聚合物结构。