公开(公告)号：WO2018170320A1

公开(公告)日：2018-09-20

申请号：PCT/US2018/022738

申请日：2018-03-15

Applicant: IMMUTRIX THERAPEUTICS, INC.

Inventor： RAE, Carol A. ,  SIMONI, Jan ,  MOELLER, John F. ,  USMANOV, Serguei

IPC: A61M1/36 ,  A61M1/34 ,  A61M1/16 ,  B01D63/02 ,  B01D71/68

CPC classification number: A61M1/3679 ,  A61M1/34 ,  B01D63/02 ,  B01D69/02 ,  B01D69/08 ,  B01D69/081 ,  B01D69/12 ,  B01D69/141 ,  B01D69/148 ,  B01D71/021 ,  B01D71/38 ,  B01D71/40 ,  B01D71/44 ,  B01D71/68 ,  B01D71/82 ,  B01D2325/02 ,  B01D2325/04 ,  B01D2325/14 ,  B01D2325/16 ,  B01D2325/20

Abstract: An extracorporeal method of treating a metabolic disorder comprising contacting a bodily fluid with (a) a hollow fiber membrane comprising a synthetic polymeric hemobiocompatible material; (b) a hollow fiber composite membrane comprising a carbonaceous material and a membrane-forming material; (c) a hollow fiber composite membrane comprising a carbonaceous material, an ion-exchange resin and a membrane-forming material, or (d) combinations thereof. A hollow fiber composite membrane comprising a micronized carbonaceous material and a membrane-forming material.

公开(公告)号：WO2017182801A1

公开(公告)日：2017-10-26

申请号：PCT/GB2017/051089

申请日：2017-04-19

Applicant: IMPERIAL INNOVATIONS LIMITED

Inventor： WANG, Bo ,  JI, Jing ,  LI, Kang

IPC: B01D61/14 ,  B01D67/00 ,  B01D71/34

CPC classification number: B01D67/0013 ,  B01D61/14 ,  B01D67/0011 ,  B01D71/34 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2325/02 ,  B01D2325/028 ,  B01D2325/20 ,  B01D2325/24

Abstract: A process for the preparation of ultrafiltration and microfiltration polymeric flat sheet separation membranes is disclosed, the process comprising a unidirectional cooling step. Membranes prepared according to the process exhibit numerous advantages over ultrafiltration and microfiltration membranes prepared via conventional processes. In particular, the membranes prepared by the present process exhibit remarkable pure water flux, superior mechanical properties and increased anti-fouling characteristics. Also disclosed are particular PVDF ultrafiltration and microfiltration membranes having improved flux, mechanical and anti-fouling properties.

Abstract translation: 公开了一种制备超滤和微滤聚合物平片分离膜的方法，该方法包括单向冷却步骤。 根据该方法制备的膜与通过常规方法制备的超滤和微滤膜相比显示出许多优点。 特别地，通过本发明方法制备的膜表现出显着的纯水通量，优异的机械性能和增加的防污特性。 还公开了具有改进的通量，机械和防污性能的特定PVDF超滤膜和微滤膜。

公开(公告)号：WO2017120195A1

公开(公告)日：2017-07-13

申请号：PCT/US2017/012136

申请日：2017-01-04

Applicant: SAUDI ARABIAN OIL COMPANY ,  ARAMCO SERVICES COMPANY

Inventor： YAHAYA, Garba, Oloriegbe ,  BAHAMDAN, Ahmad, A. ,  AL-QAHTANI, Mohammad, S. ,  HAMAD, Feras ,  AMEEN, Ahmed ,  AL-AMMAR, Abdulaziz, Y.

IPC: C10L3/10 ,  B01D53/22 ,  B01D71/64 ,  C08G73/10

CPC classification number: B01D53/228 ,  B01D67/0009 ,  B01D67/002 ,  B01D67/0093 ,  B01D69/02 ,  B01D71/64 ,  B01D71/80 ,  B01D2256/18 ,  B01D2256/245 ,  B01D2257/11 ,  B01D2257/304 ,  B01D2257/504 ,  B01D2325/20 ,  C08G73/1007 ,  C10L3/10 ,  C10L3/103 ,  C10L3/104 ,  C10L3/105 ,  C10L2290/548 ,  C10L2290/58 ,  Y02C10/10

Abstract: Compositions of and methods for separating components of a natural gas stream are disclosed. In one embodiment, the method includes receiving an inlet stream comprising natural gas, the inlet stream having an inlet pressure, and the inlet stream further comprising methane, helium, and an impurity. The method includes allowing the inlet stream to contact a block co-polyimide membrane, the block co-polyimide membrane exhibiting both higher permeability for and higher selectivity for the helium and the impurity than for the methane at the inlet pressure of the inlet stream and separating the methane from the helium and the impurity to create a retentate stream, the retentate stream comprising an increased concentration of methane relative to the inlet stream. The method also includes creating a permeate stream comprising the helium and the impurity at an increased concentration of helium and impurity relative to a concentration of helium and impurity in the inlet stream.

Abstract translation: 公开了用于分离天然气流组分和方法的组合物。 在一个实施例中，该方法包括接收包含天然气的入口流，入口流具有入口压力，并且入口流还包含甲烷，氦气和杂质。 该方法包括允许入口物流接触嵌段共聚酰亚胺膜，嵌段共聚酰亚胺膜对入口物流的入口压力表现出对于氦气和杂质具有更高的渗透性和更高的选择性以及对甲烷更高的选择性， 来自氦气和杂质的甲烷产生滞留物流，滞留物流包含相对于入口物流增加的甲烷浓度。 该方法还包括相对于入口流中的氦和杂质浓度，以增加的氦气和杂质浓度产生包含氦气和杂质的渗透物流。

公开(公告)号：WO2017103164A1

公开(公告)日：2017-06-22

申请号：PCT/EP2016/081517

申请日：2016-12-16

Applicant: VITO NV

Inventor： ORMEROD, Dominic ,  BUEKENHOUDT, Anita ,  DORBEC, Matthieu ,  PORTO-CARRERO, Wim

IPC: C11B3/00 ,  C11B3/10 ,  C11C1/08 ,  B01D67/00 ,  B01D71/02

CPC classification number: C11B3/10 ,  B01D61/027 ,  B01D67/0088 ,  B01D67/0093 ,  B01D71/024 ,  B01D2325/20 ,  C11B3/008 ,  C11C1/08

Abstract: The present invention provides a membrane based separation method for the separation or enrichment of one or more unsaturated compounds from mixtures of chemically similar organic compounds having a different degree of unsaturation, using a membrane, such as an inorganic membrane, functionalized with a metal, such as silver. The present invention also provides an inorganic membrane, preferably modified or grafted with an organic functional group, further functionalized with a metal, such as silver, for use in the membrane based separation methods of the present invention.

Abstract translation: 本发明提供了一种基于膜的分离方法，用于从具有不同不饱和度的化学类似有机化合物的混合物中分离或富集一种或多种不饱和化合物，使用膜如无机 膜，用金属例如银官能化。 本发明还提供了一种无机膜，优选用有机官能团改性或接枝，用金属例如银进一步官能化，用于本发明的基于膜的分离方法。

公开(公告)号：WO2017030937A1

公开(公告)日：2017-02-23

申请号：PCT/US2016/046722

申请日：2016-08-12

Applicant: GRADIANT CORPORATION

Inventor： ST. JOHN, Maximus, G. ,  CHOONG, Looh, Tchuin ,  GOVINDAN, Prakash, Narayan

IPC: C22B60/02 ,  C25C1/22 ,  C22B3/44

CPC classification number: B01D61/58 ,  B01D61/002 ,  B01D61/025 ,  B01D61/027 ,  B01D69/02 ,  B01D2311/25 ,  B01D2325/20

Abstract: Disclosed herein are systems and methods in which ion-selective separation and multi-stage osmotic separation is used to produce multivalent-ion-rich process streams. According to certain embodiments, multiple separations may be used to process an aqueous feed stream containing solubilized monovalent ions and solubilized multivalent ions to produce a stream enriched in the multivalent ions. The separations may be arranged, according to certain embodiments, to enhance the overall separation process such that the product stream contains - relative to the initial aqueous feed stream - a high amount of multivalent ions, a high amount of water from the aqueous feed stream, and/or a high ratio of multivalent ions to monovalent ions.

Abstract translation: 本文公开了使用离子选择分离和多级渗透分离来制备多价离子富集工艺流的系统和方法。 根据某些实施方案，多次分离可用于处理含有溶解的一价离子和溶解的多价离子的含水进料流，以产生富含多价离子的物流。 根据某些实施方案，分离可以被布置为增强总体分离过程，使得产物流相对于初始含水进料流含有大量的多价离子，来自含水进料流的大量水， 和/或多价离子与一价离子的高比例。

公开(公告)号：WO2017017171A1

公开(公告)日：2017-02-02

申请号：PCT/EP2016/067979

申请日：2016-07-28

Applicant: GAMBRO LUNDIA AB

Inventor： MALARD, Benjamin

IPC: B01D67/00 ,  B01D69/08 ,  B01D71/42 ,  B01D71/44

CPC classification number: B01D67/0009 ,  B01D67/0011 ,  B01D67/0027 ,  B01D69/08 ,  B01D69/087 ,  B01D71/42 ,  B01D71/44 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2323/28 ,  B01D2325/20

Abstract: The present disclosure relates to improved semipermeable membranes based on acrylonitrile copolymers for use in dialyzers for the extracorporeal treatment of blood in conjunction with hemodialysis, hemofiltration or hemodiafiltration. The present disclosure further relates to methods of producing such membranes.

Abstract translation: 本公开涉及基于丙烯腈共聚物的改进的半透膜，其用于透析器中，用于结合血液透析，血液滤过或血液透析滤过的体外体外治疗血液。 本公开还涉及生产这种膜的方法。

公开(公告)号：WO2016203215A1

公开(公告)日：2016-12-22

申请号：PCT/GB2016/051757

申请日：2016-06-14

Applicant: FUJIFILM MANUFACTURING EUROPE BV ,  FUJIFILM CORPORATION ,  FUJIFILM IMAGING COLORANTS LIMITED

Inventor： YONEYAMA, Satoshi ,  ITAMI, Yujiro

IPC: B01D53/22 ,  B01D69/02 ,  B01D69/12 ,  B01D71/70

CPC classification number: B01D69/12 ,  B01D53/228 ,  B01D67/0002 ,  B01D69/02 ,  B01D71/16 ,  B01D71/64 ,  B01D71/70 ,  B01D2325/04 ,  B01D2325/20

Abstract: A composite membrane comprising: (A) a porous support; (B) optionally a gutter layer; (C) a first discriminating layer; (D) an outermost layer; and (E) a non-discriminating layer interposed between the first discriminating layer (C) and the outermost layer (D); wherein the outermost layer (D) is a discriminating layer comprising a polyimide polymer.

Abstract translation: 一种复合膜，包括：（A）多孔载体; （B）任选的沟槽层; （C）第一鉴别层; （D）最外层; 和（E）插入在第一识别层（C）和最外层（D）之间的非鉴别层; 其中最外层（D）是包含聚酰亚胺聚合物的鉴别层。

公开(公告)号：WO2016196542A1

公开(公告)日：2016-12-08

申请号：PCT/US2016/035145

申请日：2016-06-01

Applicant: TUFTS UNIVERSITY

Inventor： ALEXIOU, Ayse, Asatekin ,  THOMAS, Samuel ,  KANER, Papatya ,  HU, Xiaoran

IPC: B01D69/10 ,  B01D71/06 ,  B01D67/00 ,  C02F1/44

CPC classification number: B01D67/00 ,  B01D65/08 ,  B01D69/02 ,  B01D69/10 ,  B01D71/06 ,  B01D71/62 ,  B01D71/78 ,  B01D2325/04 ,  B01D2325/20 ,  B01D2325/28 ,  B01D2325/34 ,  B01D2325/36 ,  B01D2325/38 ,  C02F1/44

Abstract: A two-layer photo-responsive membrane including a polymer layer and a support layer, the polymer layer being disposed on a surface of the support layer. The polymer layer is formed of a graft copolymer that contains a hydrophobic backbone and multiple side chains, the side chains each consisting of repeat units that switch between a hydrophobic form and a hydrophilic form upon exposure to a light of a specific wavelength. The polymer layer has a molecular weight cut-off of 3,000 to 250,000 Daltons and a thickness of 50 nm to 10 µm; and the support layer has a molecular weight cut-off of 50 to 250,000 Daltons. Also disclosed is a method of preparing this two-layer photo-responsive membrane.

Abstract translation: 包括聚合物层和支撑层的双层光响应膜，聚合物层设置在支撑层的表面上。 聚合物层由含有疏水骨架和多个侧链的接枝共聚物形成，侧链各自由在特定波长的光下暴露于疏水形式和亲水形式之间的重复单元组成。 聚合物层的分子量截留值为3000〜250,000道尔顿，厚度为50nm〜10μm; 支撑层的分子量截止值为50〜250,000道尔顿。 还公开了制备该双层光响应膜的方法。

公开(公告)号：WO2016182886A1

公开(公告)日：2016-11-17

申请号：PCT/US2016/031130

申请日：2016-05-06

Applicant: COMPACT MEMBRANE SYSTEMS, INC.

Inventor： KOIZUMI, Yosuke

IPC: C07C7/144 ,  B01J39/18 ,  B01J47/12 ,  B01D71/32 ,  B01D53/52 ,  B01D71/82 ,  B01D67/00

CPC classification number: B01D71/76 ,  B01D53/228 ,  B01D69/02 ,  B01D69/12 ,  B01D71/26 ,  B01D71/32 ,  B01D71/34 ,  B01D71/82 ,  B01D2325/20 ,  B32B3/26 ,  B32B27/08 ,  B32B27/205 ,  B32B27/28 ,  B32B27/286 ,  B32B27/322 ,  B32B2307/70 ,  B32B2307/724 ,  B32B2307/732 ,  C07C7/144 ,  C08F4/00 ,  C08F214/202 ,  C08F216/1466 ,  C08F2216/1475 ,  C08G61/10

Abstract: Improved membranes which can separate alkanes and alkenes, and have at least one layer of a Group 11 metal ionomer, are made by exposing the ionomer to a strong Bronsted acid having a pKa of about 1 or less. The membranes have longer useful lives and have better initial permeances of alkenes.

Abstract translation: 通过将离聚物暴露于pKa为约1或更小的强布朗斯台德酸制备可分离烷烃和烯烃并具有至少一层第11族金属离聚物的改进的膜。 膜具有更长的使用寿命并且具有更好的烯烃的初始渗透性。

公开(公告)号：WO2016105614A1

公开(公告)日：2016-06-30

申请号：PCT/US2015/053135

申请日：2015-09-30

Applicant: EMD MILLIPORE CORPORATION

Inventor： PETERS, Antoni ,  GODDARD, Philip, M.

IPC: B01D65/08 ,  A61L2/00 ,  B01D67/00 ,  B01D71/68 ,  C07K16/00 ,  C07K1/34

CPC classification number: C12M37/02 ,  A61L2/0017 ,  B01D61/14 ,  B01D65/08 ,  B01D67/0088 ,  B01D67/009 ,  B01D67/0093 ,  B01D71/68 ,  B01D71/82 ,  B01D2323/30 ,  B01D2323/36 ,  B01D2323/40 ,  B01D2325/20 ,  C07K1/34

Abstract: Compositions and methods are provided for removing viral contaminants from a chemically defined cell culture medium by using microporous membranes having a coating with acomposition resistant to or exhibiting reduced fouling by one or more components in a chemically defined cell culture medium. The coating comprises a copolymer formed from monomer solutions comprising diacetone acrylamide (DACm) and poly(ethylene glycol) diacrylate (PEGDA).

Abstract translation: 提供了组合物和方法，用于通过使用具有抗化学定义的细胞培养基中一种或多种组分的抗结皮或显示减少结垢的涂层的微孔膜从化学确定的细胞培养基中除去病毒污染物。 涂层包含由包含双丙酮丙烯酰胺（DACm）和聚（乙二醇）二丙烯酸酯（PEGDA）的单体溶液形成的共聚物。