METHOD OF MAKING SOLID BEADS
    2.
    发明申请
    METHOD OF MAKING SOLID BEADS 审中-公开
    制造实心珠的方法

    公开(公告)号:WO2012042274A1

    公开(公告)日:2012-04-05

    申请号:PCT/GB2011/051859

    申请日:2011-09-30

    IPC分类号: B01J2/08 B01J2/18

    CPC分类号: B01J2/06 B01J2/08 B01J2/18

    摘要: A method of forming solid beads, the method comprising: Providing a first liquid comprising a solute and a solvent Forming liquid droplets of the first liquid Contacting the liquid droplets with a second liquid so as to cause the solvent to exit the droplets, thus forming solid beads, the solute comprising a polymer, the concentration of polymer in the first liquid being at least 7% w/v., the solubility of the solvent in the second liquid being at least 5g of solvent per 100ml of second liquid.

    摘要翻译: 一种形成固体珠的方法,所述方法包括:提供包含溶质和溶剂的第一液体形成第一液体的液滴将液滴与第二液体接触,以使溶剂离开液滴,从而形成固体 小珠,包含聚合物的溶质,第一液体中聚合物的浓度为至少7%w / v,溶剂在第二液体中的溶解度为每100ml第二液体至少为5g溶剂。

    PROCEDE DE PREPARATION DE BILLES CONTENANT UNE MATRICE MINERALE RETICULEE.
    4.
    发明申请
    PROCEDE DE PREPARATION DE BILLES CONTENANT UNE MATRICE MINERALE RETICULEE. 审中-公开
    用于制备含有交联矿物基质的珠粒的方法

    公开(公告)号:WO2004009229A1

    公开(公告)日:2004-01-29

    申请号:PCT/FR2003/002285

    申请日:2003-07-18

    IPC分类号: B01J13/14

    摘要: L'invention concerne un procédé pour la préparation de billes contenant une matrice minérale réticulée, et les billes obtenues. Le procédé consiste à préparer des billes gélifiées en versant goutte à goutte une suspension contenant un précurseur de la matrice minérale et un alginate, dans une solution d'un sel de cation plurivalent dont le pH est inférieur à 3, et à réticuler le précurseur de la matrice minérale par un procédé sol-gel. Le procédé est particulièrement utile pour la préparation de billes de silice ou d'alumine réticulée ayant une dimension millimétrique.

    摘要翻译: 本发明涉及一种制备含有交联矿物基质的珠粒和所得珠粒的方法。 该方法包括通过将含有矿物基质和藻酸盐前体的悬浮液滴入到pH小于3的多价阳离子盐溶液中,并通过溶胶 - 凝胶法将矿物基质前体交联,从而制备凝胶珠, 凝胶过程。 该方法对于制备具有毫米尺寸的交联二氧化硅或氧化铝珠粒特别有用。

    MICROPARTICLE PRODUCTION PROCESS AND APPARATUS
    7.
    发明申请
    MICROPARTICLE PRODUCTION PROCESS AND APPARATUS 审中-公开
    微粒生产方法和设备

    公开(公告)号:WO2017103113A2

    公开(公告)日:2017-06-22

    申请号:PCT/EP2016/081436

    申请日:2016-12-16

    IPC分类号: B01J2/04 B01J2/08 B01J2/18

    CPC分类号: B01J2/04 B01J2/08 B01J2/18

    摘要: Provided is an apparatus for producing solid polymeric microparticles, the apparatus comprising a plurality of liquid droplet generators for forming liquid droplets of a first liquid, and a nozzle for forming a jet of a second liquid, wherein the plurality of liquid droplet generators and the nozzle are arranged relative to each other such that, in use, liquid droplets from the plurality of liquid droplet generators pass through a gas into said jet of second liquid. Also provided is a process for producing solid microparticles, the process comprising: providing a first liquid comprising a solute and a solvent, the solute comprising a biocompatible polymer, the concentration of polymer in the first liquid being at least 10% w/v, 'w' being the weight of the polymer and 'ν' being the volume of the solvent, providing a plurality of liquid droplet generators operable to generate liquid droplets, providing a jet of a second liquid, causing the plurality of liquid droplet generators to form liquid droplets of the first liquid, passing the liquid droplets through a gas to contact the jet of the second liquid so as to cause the solvent to exit the droplets, thus forming solid microparticles, the solubility of the solvent in the second liquid being at least 5g of solvent per 100ml of second liquid, the solvent being substantially miscible with the second liquid.

    摘要翻译: 提供了一种用于生产固体聚合物微粒的装置,所述装置包括用于形成第一液体的液滴的多个液滴发生器和用于形成第二液体的射流的喷嘴,其中, 多个液滴产生器和喷嘴相对于彼此布置,使得在使用中,来自多个液滴产生器的液滴通过气体进入所述第二液体射流。 还提供了生产固体微粒的方法,所述方法包括:提供包含溶质和溶剂的第一液体,所述溶质包含生物相容性聚合物,第一液体中聚合物的浓度为至少10%w / v, w'为聚合物的重量,'v'为溶剂的体积,提供多个可操作以产生液滴的液滴发生器,提供第二液体的射流,使多个液滴发生器形成液体 使液滴通过气体与第二液体的射流接触以使溶剂离开液滴从而形成固体微粒,溶剂在第二液体中的溶解度至少为5g 的溶剂,每100ml第二液体溶剂与第二液体基本上混溶。

    PRODUCTION OF PARTICLES
    9.
    发明申请
    PRODUCTION OF PARTICLES 审中-公开
    生产颗粒物

    公开(公告)号:WO2014057424A3

    公开(公告)日:2014-10-16

    申请号:PCT/IB2013059211

    申请日:2013-10-08

    申请人: CSIR

    摘要: A process for producing product particles includes producing, by means of a droplet-based microfluidic technique, a plurality of primary droplets of a first liquid phase dispersed in a continuous second liquid phase. The first liquid phase is immiscible with the second liquid phase. An emulsion of the primary droplets in the second liquid phase is formed. A liquid adjunct is admixed with the emulsion. The liquid adjunct comprises secondary droplets of a third liquid phase, and/or particles, dispersed in a fourth liquid phase. The third liquid phase and/or the particles and/or the fourth liquid phase include a reagent capable of reacting with a component of the first liquid phase. The secondary droplets and/or the particles (whichever is/are present) are smaller than the primary droplets. The secondary droplets are allowed to coalesce with the primary droplets, and/or the particles are allowed to mix with primary droplets, thereby to form tertiary droplets. In the tertiary droplets, the reagent is allowed to react with the component of the first liquid phase, so that product particles are formed from the tertiary droplets. The product particles are recovered from the second liquid phase.

    摘要翻译: 用于生产产品颗粒的方法包括通过基于液滴的微流体技术制备分散在连续的第二液相中的第一液相的多个初级液滴。 第一液相与第二液相不混溶。 在第二液相中形成初级液滴的乳液。 液体助剂与乳液混合。 液体助剂包括分散在第四液相中的第三液相和/或颗粒的二次液滴。 第三液相和/或颗粒和/或第四液相包括能够与第一液相的组分反应的试剂。 次级液滴和/或颗粒(以存在的数量为准)小于初级液滴。 允许二次液滴与主液滴聚结,和/或允许颗粒与初级液滴混合,从而形成三次液滴。 在第三液滴中,允许试剂与第一液相的组分反应,使得产物颗粒由第三液滴形成。 产物颗粒从第二液相中回收。

    METHOD OF PREPARING SILICA AEROGEL GRANULES
    10.
    发明申请
    METHOD OF PREPARING SILICA AEROGEL GRANULES 审中-公开
    制备硅胶气凝胶颗粒的方法

    公开(公告)号:WO2012044052A2

    公开(公告)日:2012-04-05

    申请号:PCT/KR2011/007125

    申请日:2011-09-28

    摘要: Disclosed herein is a method of method of preparing transparent or nontransparent silica aerogel granules. The method includes forming a granular wet gel by spraying a silica sol into alcohol, the silica sol being prepared by mixing a water glass solution or an opacifier-containing water glass solution with an inorganic acid solution, forming a granular alcohol gel through gelation aging and solvent substitution of the granular wet gel in alcohol, hydrophobically modifying the surface of the granular alcohol gel using an organic silane compound, and drying the surface modified gel at ambient pressure or in a vacuum. The method may prepare silica aerogel granules in a short period of time through heat treatment at a relatively low temperature and at ambient pressure or in a vacuum, thereby ensuring excellent economic feasibility, continuity and reliability, suited for mass production.

    摘要翻译: 本文公开了制备透明或不透明二氧化硅气凝胶颗粒的方法。 该方法包括通过将硅溶胶喷雾到醇中形成粒状湿凝胶,所述硅溶胶通过将水玻璃溶液或含有不透明剂的水玻璃溶液与无机酸溶液混合,通过凝胶老化形成粒状醇凝胶而制备, 用醇溶剂置换粒状湿凝胶,用有机硅烷化合物疏水改性粒状醇凝胶表面,并在环境压力或真空下干燥表面改性凝胶。 该方法可以在相对较低的温度和环境压力下或在真空中通过热处理在短时间内制备二氧化硅气凝胶颗粒,从而确保优良的经济可行性,连续性和可靠性,适合大规模生产。